ATA224988A - WATER-SOLUBLE MONOESTERS AS SOLUBILIZERS FOR PHARMACOLOGICAL ACTIVE SUBSTANCES AND PHARMACEUTICAL AUXILIARY SUBSTANCES - Google Patents

WATER-SOLUBLE MONOESTERS AS SOLUBILIZERS FOR PHARMACOLOGICAL ACTIVE SUBSTANCES AND PHARMACEUTICAL AUXILIARY SUBSTANCES

Info

Publication number
ATA224988A
ATA224988A AT0224988A AT224988A ATA224988A AT A224988 A ATA224988 A AT A224988A AT 0224988 A AT0224988 A AT 0224988A AT 224988 A AT224988 A AT 224988A AT A224988 A ATA224988 A AT A224988A
Authority
AT
Austria
Prior art keywords
solubilizers
water
substances
pharmacological active
pharmaceutical auxiliary
Prior art date
Application number
AT0224988A
Other languages
German (de)
Other versions
AT395819B (en
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of ATA224988A publication Critical patent/ATA224988A/en
Application granted granted Critical
Publication of AT395819B publication Critical patent/AT395819B/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
AT0224988A 1987-09-15 1988-09-14 WATER-SOLUBLE MONOESTERS AS SOLUBILIZERS FOR PHARMACOLOGICAL ACTIVE SUBSTANCES AND PHARMACEUTICAL AUXILIARY SUBSTANCES AT395819B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3730909 1987-09-15
DE3802355 1988-01-27

Publications (2)

Publication Number Publication Date
ATA224988A true ATA224988A (en) 1992-08-15
AT395819B AT395819B (en) 1993-03-25

Family

ID=25859774

Family Applications (1)

Application Number Title Priority Date Filing Date
AT0224988A AT395819B (en) 1987-09-15 1988-09-14 WATER-SOLUBLE MONOESTERS AS SOLUBILIZERS FOR PHARMACOLOGICAL ACTIVE SUBSTANCES AND PHARMACEUTICAL AUXILIARY SUBSTANCES

Country Status (24)

Country Link
JP (1) JP3090666B2 (en)
KR (1) KR0131084B1 (en)
AT (1) AT395819B (en)
AU (1) AU628787B2 (en)
BE (1) BE1001204A5 (en)
CA (1) CA1338775C (en)
CH (1) CH683672A5 (en)
DK (1) DK175132B1 (en)
ES (1) ES2012118A6 (en)
FI (1) FI94837C (en)
FR (1) FR2620336B1 (en)
GB (1) GB2209671B (en)
GR (1) GR1002243B (en)
HU (1) HU205010B (en)
IE (1) IE61195B1 (en)
IL (1) IL87746A (en)
IT (1) IT1224886B (en)
LU (1) LU87335A1 (en)
MY (1) MY103769A (en)
NL (1) NL195094C (en)
NO (1) NO179434C (en)
NZ (1) NZ226163A (en)
PT (1) PT88492B (en)
SE (1) SE503279C2 (en)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6007840A (en) * 1988-09-16 1999-12-28 Novartis Ag Pharmaceutical compositions comprising cyclosporins
KR0148748B1 (en) * 1988-09-16 1998-08-17 장 크라메르, 한스 루돌프 하우스 A multiphase cyclosporin composition
GR1000466B (en) * 1989-01-28 1992-07-30 Sandoz Ag Preparation method of novel pharmaceutical forms of cyclosporine
GB2230440B (en) * 1989-02-09 1993-05-19 Sandoz Ltd Novel cyclosporin galenic forms
GB8916901D0 (en) 1989-07-24 1989-09-06 Sandoz Ltd Improvements in or relating to organic compounds
US6262022B1 (en) 1992-06-25 2001-07-17 Novartis Ag Pharmaceutical compositions containing cyclosporin as the active agent
ATE147619T1 (en) 1992-05-13 1997-02-15 Sandoz Ag OPTHALMIC COMPOSITIONS CONTAINING A CYCLOSPORIN
ES2168271T3 (en) 1992-09-25 2002-06-16 Novartis Ag PHARMACEUTICAL COMPOSITIONS CONTAINING CYCLOSPORINS.
DE69435104D1 (en) * 1993-09-28 2008-07-31 Scherer Gmbh R P Production of soft gelatine capsules
CA2231404C (en) 1994-11-03 2009-02-17 Arzneimittelwerk Dresden Gmbh Novel cyclosporine preparation forms for oral administration of simple composition and high bio-availability, and process for producing them
US5827822A (en) * 1996-03-25 1998-10-27 Sangstat Medical Corporation Cyclosporin a formulations as nanoparticles
US5766629A (en) 1995-08-25 1998-06-16 Sangstat Medical Corporation Oral cyclosporin formulations
US5962019A (en) * 1995-08-25 1999-10-05 Sangstat Medical Corporation Oral cyclosporin formulations
US5834017A (en) * 1995-08-25 1998-11-10 Sangstat Medical Corporation Oral cyclopsporin formulations
DE19544507B4 (en) 1995-11-29 2007-11-15 Novartis Ag Cyclosporin containing preparations
TW414696B (en) * 1996-07-01 2000-12-11 Mitsubishi Kagaku Foods Kk Anti-bacteria agent
DE29824679U1 (en) 1997-01-30 2002-03-28 Novartis Ag Pharmaceutical compositions
GB2326337A (en) * 1997-06-20 1998-12-23 Phares Pharma Holland Homogeneous lipid compositions for drug delivery
US7732404B2 (en) 1999-12-30 2010-06-08 Dexcel Ltd Pro-nanodispersion for the delivery of cyclosporin
EP1558215A4 (en) * 2003-10-14 2007-09-12 Wockhardt Ltd Sterile gelling agents
JP5422871B2 (en) * 2006-10-24 2014-02-19 不二製油株式会社 Isoflavones composition

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL284933A (en) * 1961-10-31
GB1134878A (en) * 1966-05-12 1968-11-27 Suga Kazuo Improvements in and relating to oryzanol solutions and compositions
FR5986M (en) * 1966-11-22 1968-06-21
BE787842A (en) * 1971-08-25 1972-12-18 Sumito Chemical Cy Ltd PROCESS FOR PREPARING AN AQUEOUS SUSPENSION OF STABLE CRYSTALS OF THE NON-BETA TYPE OF HIGHER FATTY ACID ESTERS OF CHLORAMPHENICOL
JPS53107408A (en) * 1977-02-28 1978-09-19 Yamanouchi Pharmaceut Co Ltd Micellar preparation for rectal infusion
DE2907460A1 (en) * 1978-03-07 1979-09-13 Sandoz Ag NEW RESORBABLE GALENIC COMPOSITIONS
JPS57128634A (en) * 1981-02-03 1982-08-10 Eisai Co Ltd Elastase-containing compound increasing absorption
EP0179583A1 (en) * 1984-10-04 1986-04-30 Merck & Co. Inc. A system for enhancing the water dissolution rate and solubility of poorly soluble drugs
JPS61280435A (en) * 1985-04-04 1986-12-11 Kanji Takada Lymph orienting preparation of cyclosporin

Also Published As

Publication number Publication date
IL87746A (en) 1992-07-15
GB8821443D0 (en) 1988-10-12
FI884192A0 (en) 1988-09-13
DK511188D0 (en) 1988-09-14
DK511188A (en) 1989-03-16
GR880100602A (en) 1989-06-22
CA1338775C (en) 1996-12-10
LU87335A1 (en) 1989-04-06
DK175132B1 (en) 2004-06-14
IE882772L (en) 1989-03-15
FR2620336A1 (en) 1989-03-17
NL8802275A (en) 1989-04-03
AU2217288A (en) 1989-04-27
MY103769A (en) 1993-09-30
BE1001204A5 (en) 1989-08-16
IT8848349A0 (en) 1988-09-14
NO179434C (en) 1996-10-09
FI94837B (en) 1995-07-31
NO884052D0 (en) 1988-09-13
NO179434B (en) 1996-07-01
HU205010B (en) 1992-03-30
NL195094C (en) 2003-12-17
SE8803221D0 (en) 1988-09-13
FR2620336B1 (en) 1991-10-25
FI94837C (en) 1995-11-10
KR0131084B1 (en) 1998-04-17
FI884192A (en) 1989-03-16
HUT49494A (en) 1989-10-30
CH683672A5 (en) 1994-04-29
IE61195B1 (en) 1994-10-19
GB2209671B (en) 1991-11-13
GB2209671A (en) 1989-05-24
JPH01151526A (en) 1989-06-14
NZ226163A (en) 1991-08-27
IT1224886B (en) 1990-10-24
SE8803221L (en) 1989-03-16
AU628787B2 (en) 1992-09-24
ES2012118A6 (en) 1990-03-01
IL87746A0 (en) 1989-02-28
NO884052L (en) 1989-03-16
GR1002243B (en) 1996-04-22
SE503279C2 (en) 1996-05-13
PT88492B (en) 1993-03-31
PT88492A (en) 1988-10-01
KR890004694A (en) 1989-05-09
AT395819B (en) 1993-03-25
JP3090666B2 (en) 2000-09-25

Similar Documents

Publication Publication Date Title
ATA224988A (en) WATER-SOLUBLE MONOESTERS AS SOLUBILIZERS FOR PHARMACOLOGICAL ACTIVE SUBSTANCES AND PHARMACEUTICAL AUXILIARY SUBSTANCES
ATA154489A (en) SOLID PHARMACEUTICAL RANITIDINE PREPARATIONS
ATA214289A (en) CYCLOSPORINE CONTAINING PHARMACEUTICAL COMPOSITION
DK0589843T3 (en) Cyclosporin-containing pharmaceutical preparations
NO922005D0 (en) PHARMACEUTICAL PREPARATIONS
DK481989A (en) PHARMACEUTICAL FORMULATIONS
IT1243541B (en) ADMINISTRATION DEVICE IN PARTICULAR OF PHARMACEUTICAL SUBSTANCE
DE10199066I1 (en) Pharmaceutical composition
DE69231965T2 (en) PHARMACEUTICAL FORMULATIONS
DK362189D0 (en) PHARMACEUTICAL PREPARATION FOR INTRAVENOES ADMINISTRATION
KR910700249A (en) New therapeutically active compounds and methods for their preparation
DE69332801T2 (en) TASTE-MASKED PHARMACEUTICAL SUBSTANCES
ATE188961T1 (en) 1-PHENYL-2-DIMETHYLAMINOMETHYL-CYCLOHEXANE-1-OL COMPOUNDS AS PHARMACEUTICAL ACTIVE INGREDIENTS
ATE183495T1 (en) 6-DIMETHYLAMINOMETHYL-1-PHENYL-CYCLO-HEXANE COMPOUNDS AS PHARMACEUTICAL ACTIVE INGREDIENTS
ATA27290A (en) NEW GALENIC FORMULATIONS CONTAINING CYCLOSPORINE
DE3882157D1 (en) PHARMACEUTICAL PREPARATIONS CONTAINING NON-STEROX ANTI-IGNITION AGENTS.
DE59310248D1 (en) Progestogen-based pharmaceutical preparation
DE69013557D1 (en) Bioactive compounds coupled to liposomes and their use in pharmaceutical preparations.
IT1223343B (en) PHARMACEUTICAL FORMULATIONS FOR TRANSDERMAL ADMINISTRATION
DE69012031D1 (en) Optically active benzyl alcohol compound and pharmaceutical composition.
DK298389A (en) PHARMACEUTICAL PREPARATION FOR TOPICAL USE INCLUDING AN AMINE-FUNCTIONAL MEDICINE
IL93986A0 (en) Improvements in and relating to pharmaceutical formulations
IT8822902A0 (en) LIPID PHARMACEUTICAL COMPOSITIONS FOR TOPICAL USE SUITABLE FOR CARRYING A WATER-SOLUBLE ANTI-INFLAMMATORY ACTIVE INGREDIENT
DE69122229T2 (en) PENCICLOVIR CONTAINING PHARMACEUTICAL FORMULATION
ATA133288A (en) PHARMACEUTICAL COMPOSITION

Legal Events

Date Code Title Description
ELA Expired due to lapse of time