ATA208987A - Immortalisierte zellinie, verfahren zu ihrer herstellung und verfahren zur herstellung von monoklonalen antikörpern sowie diagnoseverfahren und -mittel - Google Patents

Immortalisierte zellinie, verfahren zu ihrer herstellung und verfahren zur herstellung von monoklonalen antikörpern sowie diagnoseverfahren und -mittel

Info

Publication number
ATA208987A
ATA208987A AT0208987A AT208987A ATA208987A AT A208987 A ATA208987 A AT A208987A AT 0208987 A AT0208987 A AT 0208987A AT 208987 A AT208987 A AT 208987A AT A208987 A ATA208987 A AT A208987A
Authority
AT
Austria
Prior art keywords
production
cell line
monoclonal antibodies
diagnostic methods
immortalized cell
Prior art date
Application number
AT0208987A
Other languages
English (en)
Other versions
AT398080B (de
Original Assignee
Genetic Systems Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genetic Systems Corp filed Critical Genetic Systems Corp
Publication of ATA208987A publication Critical patent/ATA208987A/de
Application granted granted Critical
Publication of AT398080B publication Critical patent/AT398080B/de

Links

Classifications

    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
    • F04B25/00—Multi-stage pumps
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
    • C07K16/1036—Retroviridae, e.g. leukemia viruses
    • C07K16/1045—Lentiviridae, e.g. HIV, FIV, SIV
    • C07K16/1054—Lentiviridae, e.g. HIV, FIV, SIV gag-pol, e.g. p17, p24
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701—Specific hybridization probes
    • C12Q1/702—Specific hybridization probes for retroviruses
    • C12Q1/703—Viruses associated with AIDS
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16111—Human Immunodeficiency Virus, HIV concerning HIV env
    • C12N2740/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16211—Human Immunodeficiency Virus, HIV concerning HIV gagpol
    • C12N2740/16222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • AIDS & HIV (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Mechanical Engineering (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AT0208987A 1986-08-20 1987-08-20 Immortalisierte zellinie, verfahren zu ihrer herstellung und verfahren zur herstellung von monoklonalen antikörpern sowie diagnoseverfahren und -mittel AT398080B (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US89827386A 1986-08-20 1986-08-20
US4502687A 1987-05-01 1987-05-01
US6799687A 1987-06-29 1987-06-29

Publications (2)

Publication Number Publication Date
ATA208987A true ATA208987A (de) 1994-01-15
AT398080B AT398080B (de) 1994-09-26

Family

ID=27366600

Family Applications (1)

Application Number Title Priority Date Filing Date
AT0208987A AT398080B (de) 1986-08-20 1987-08-20 Immortalisierte zellinie, verfahren zu ihrer herstellung und verfahren zur herstellung von monoklonalen antikörpern sowie diagnoseverfahren und -mittel

Country Status (28)

Country Link
JP (1) JPS6485928A (de)
KR (1) KR920008744B1 (de)
AT (1) AT398080B (de)
AU (1) AU616156B2 (de)
BE (1) BE1000811A4 (de)
CH (1) CH675728A5 (de)
CS (1) CS275838B6 (de)
DE (1) DE3727703A1 (de)
DK (1) DK433087A (de)
ES (1) ES2010727A6 (de)
FI (1) FI873553A (de)
FR (1) FR2603107B1 (de)
GB (1) GB2196634B (de)
GR (1) GR871298B (de)
HU (1) HU214439B (de)
IE (1) IE60671B1 (de)
IL (1) IL83580A (de)
IT (1) IT1222518B (de)
LU (1) LU86972A1 (de)
NL (1) NL8701950A (de)
NO (2) NO300462B1 (de)
NZ (1) NZ221440A (de)
OA (1) OA08652A (de)
PL (1) PL155084B1 (de)
PT (1) PT85567B (de)
SE (1) SE506025C2 (de)
YU (1) YU152587A (de)
ZW (1) ZW15487A1 (de)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AP96A (en) * 1986-06-03 1990-08-12 The Usa Dept Of Commerce Small peptides which inhibit binding to T-4 receptors and act as immunogens.
AU625720B2 (en) * 1987-05-01 1992-07-16 Genetic Systems Corporation Monoclonal antibodies to specific antigenic regions of the human immunodeficiency virus and methods for use
US6657050B1 (en) 1987-05-29 2003-12-02 Tanox, Inc. Chimeric viral-neutralizing immunoglobulins
DE3853779T2 (de) * 1987-05-29 1995-09-07 Baylor College Medicine Hiv-1 neutralisierende monoklonale antikörper.
US5834599A (en) * 1987-05-29 1998-11-10 Tanox Biosystems, Inc. Immunoconjugates which neutralize HIV-1 infection
US5981278A (en) * 1987-05-29 1999-11-09 Tanox, Inc. Chimeric monoclonal antibodies which neutralize HIV-1 infection and their applications in therapy and prevention for AIDS
DE68926499T2 (de) * 1988-01-26 1996-12-19 The United States Of America, Represented By The Secretary, U.S. Department Of Commerce, Springfield, Va. Synthetisches antigen zum bewirken einer anti-hiv-reaktion
CA1341285C (en) * 1988-02-12 2001-08-14 Chang Yi Wang Synthetic peptides for the detection of antibodies to hiv gp120 envelope protein for diagnosis of aids and pre-aids conditions and as vaccines
IL90048A0 (en) * 1988-04-25 1989-12-15 Merck & Co Inc Recombinant gag precursor of hiv,its preparation and its use as aids vaccine
US5562905A (en) * 1988-04-26 1996-10-08 E. I. Du Pont De Nemours And Company Human immunodeficiency virus (hiv) env-coded peptide capable of eliciting hiv-inhibiting antibodies in mammals
EP0339504A3 (de) * 1988-04-26 1990-09-12 The Du Pont Merck Pharmaceutical Company Menschliches immunoinsuffizientes Virus (HIV) env-codiertes Peptid, welches im Stande ist, die HIV hemmenden Antikörper bei Säugetieren hervorzurufen
FR2632310B1 (fr) * 1988-06-06 1992-04-10 Pasteur Institut Peptides ayant des proprietes protectrices d'un virus pathogene du type hiv dans des cellules sensibles
EP0436634A1 (de) * 1988-10-03 1991-07-17 Repligen Corporation Hiv-proteine und peptide und deren verwendung zur diagnose, prophylaxe und therapie von aids
EP0421626A1 (de) * 1989-09-19 1991-04-10 Merck & Co. Inc. Vakzin gegen AIDS und Hepatitis B
SE9000333D0 (sv) * 1990-01-31 1990-01-31 Britta Wahren Monoklonal antikropp
SE468168B (sv) * 1990-02-20 1992-11-16 Replico Medical Ab Hiv-1, p24 peptider, diagnostiska antigener och foerfarande foer saerskiljande diagnostik av preliminaert hiv-1 positiva serumprov
JPH03271233A (ja) * 1990-03-19 1991-12-03 Inst Pasteur ウイルスエンベロープ糖タンパク質及びその糖タンパク質の中和エピトープに対応するペプチドの間の相乗作用による、ウイルス性感染に対する防御の誘発
CA2047042A1 (en) * 1990-07-19 1992-01-20 John Hannah Cyclic hiv principal neutralizing determinant peptides
CA2047078A1 (en) * 1990-07-19 1992-01-20 Steven S. Bondy Cyclic hiv principal neutralizing determinant peptides
JPH05310785A (ja) * 1991-09-30 1993-11-22 Nitto Denko Corp Ｈｉｖ関連環状ペプチドおよびこれを固定化した吸着体
WO1993020102A1 (en) * 1992-03-27 1993-10-14 Peptide Technology Limited Peptide t and related peptides in the treatment of inflammation, including multiple sclerosis
BRPI0620566B8 (pt) 2005-12-09 2021-05-25 Vectus Biosystems Ltd composição, composição para o tratamento profilático ou terapêutico de fibrose miocardial ou uma condição associada, composição para o tratamento profilático ou terapêutico de hipertensão, uso de uma composição, uso de vip ou de um fragmento do mesmo e uso de um vip
WO2010026940A1 (ja) 2008-09-02 2010-03-11 日本特殊陶業株式会社 スパークプラグ

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9328391B1 (en) * 1984-08-22 2016-05-03 The United States Of America As Represented By The Secretary, Department Of Health And Human Services Cloning and expression of HIV-1 DNA
GB8501473D0 (en) * 1985-01-21 1985-02-20 Pasteur Institut Cloned dna sequences
DE3587181T2 (de) * 1984-10-18 1993-06-24 Centre Nat Rech Scient F antigene vom menschlichen immunodefizienz-virus und deren verwendungen.
CA1341423C (en) * 1984-10-31 2003-03-04 Paul A. Luciw Recombinant proteins of viruses associated with lymphadenopathy syndrome and/or acquired immune deficiency syndrome
IE64785B1 (en) * 1985-04-08 1995-09-06 Genetic Systems Corp Expression of immunologically reactive viral proteins
EP0220234B1 (de) * 1985-04-08 1994-08-03 Genetic Systems Corporation EXPRESSION UND DIAGNOSE MIT gag-KODIERTEN PEPTIDEN, DIE MIT ANTIKÖRPERN GEGEN LAV IMMUNOLOGISCH REAKTIV SIND
FI861626A (fi) * 1985-04-19 1986-10-20 Hoffmann La Roche Foervaervat immunbristsyndrom (aids) -relaterat viralt rekombinant hoeljeprotein samt ett testfoerfarande foer aids.
WO1986006414A1 (en) * 1985-04-29 1986-11-06 Genetic Systems Corporation Synthetic antigens for the detection of aids-related disease
GB8525615D0 (en) * 1985-10-17 1985-11-20 Hoffmann La Roche Polypeptides
EP0245362B1 (de) * 1985-10-24 1994-06-29 Ronald C. Kennedy Synthetische peptide und deren verwendung zur diagnose und impfung für aids und arc
WO1987002988A1 (en) * 1985-11-07 1987-05-21 President And Fellows Of Harvard College T-cell lymphotrophic virus protein and assay
US4734362A (en) * 1986-02-03 1988-03-29 Cambridge Bioscience Corporation Process for purifying recombinant proteins, and products thereof
US4772547A (en) * 1986-02-03 1988-09-20 Hoffmann-La Roche Inc. HTLV-III envelope peptides
US4925784A (en) * 1986-04-04 1990-05-15 Hoffmann-La Roche Inc. Expression and purification of an HTLV-III gag/env gene protein
IE63109B1 (en) * 1986-06-23 1995-03-22 Genetic Systems Corp Human monoclonal antibody to lymphadenopathy-associated virus
EP0255190A3 (de) * 1986-08-01 1990-08-29 Repligen Corporation Rekombinante Polypeptide und ihre Verwendungen sowie Test für den AIDS-Virus
WO1988005051A1 (en) * 1986-12-30 1988-07-14 United States Of America, Represented By The Unite Synthetic peptides which induce cellular immunity of the aids virus and aids viral proteins

Also Published As

Publication number Publication date
PL155084B1 (en) 1991-10-31
CS275838B6 (en) 1992-03-18
IT1222518B (it) 1990-09-05
HUT44619A (en) 1988-03-28
PL267401A1 (en) 1988-07-21
NO934897L (no) 1993-12-29
AU616156B2 (en) 1991-10-24
NO934897D0 (no) 1993-12-29
NO873495L (no) 1988-02-22
DK433087D0 (da) 1987-08-19
KR890002547A (ko) 1989-04-10
IE60671B1 (en) 1994-08-10
SE506025C2 (sv) 1997-11-03
NO302176B1 (no) 1998-02-02
KR920008744B1 (ko) 1992-10-09
FI873553A0 (fi) 1987-08-17
CS8706136A2 (en) 1990-08-14
PT85567A (en) 1987-09-01
BE1000811A4 (fr) 1989-04-11
GB2196634A (en) 1988-05-05
AT398080B (de) 1994-09-26
IE872219L (en) 1988-02-20
NO873495D0 (no) 1987-08-19
CH675728A5 (de) 1990-10-31
HU214439B (hu) 1998-03-30
AU7720187A (en) 1988-05-19
LU86972A1 (fr) 1988-03-02
GB2196634B (en) 1991-05-15
DK433087A (da) 1988-02-21
NL8701950A (nl) 1988-03-16
ES2010727A6 (es) 1989-12-01
NO300462B1 (no) 1997-06-02
PT85567B (pt) 1991-02-08
FR2603107B1 (fr) 1992-04-24
NZ221440A (en) 1991-11-26
YU152587A (sh) 1992-09-07
IT8721678A0 (it) 1987-08-19
IL83580A0 (en) 1988-01-31
OA08652A (fr) 1988-11-30
SE8703225D0 (sv) 1987-08-19
ZW15487A1 (en) 1988-09-14
FI873553A (fi) 1988-02-21
SE8703225L (sv) 1988-02-21
IL83580A (en) 1992-11-15
DE3727703A1 (de) 1988-05-05
GB8719587D0 (en) 1987-09-23
FR2603107A1 (fr) 1988-02-26
GR871298B (en) 1988-01-12
JPS6485928A (en) 1989-03-30

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RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties