ATA204576A - Verfahren zur herstellung von neuen fluor- prostaglandinen - Google Patents

Verfahren zur herstellung von neuen fluor- prostaglandinen

Info

Publication number
ATA204576A
ATA204576A AT204576A AT204576A ATA204576A AT A204576 A ATA204576 A AT A204576A AT 204576 A AT204576 A AT 204576A AT 204576 A AT204576 A AT 204576A AT A204576 A ATA204576 A AT A204576A
Authority
AT
Austria
Prior art keywords
prostaglandines
manufacturing new
new fluorine
fluorine
manufacturing
Prior art date
Application number
AT204576A
Other languages
English (en)
Other versions
AT351189B (de
Original Assignee
Erba Carlo Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from IT21493/75A external-priority patent/IT1049373B/it
Application filed by Erba Carlo Spa filed Critical Erba Carlo Spa
Publication of ATA204576A publication Critical patent/ATA204576A/de
Application granted granted Critical
Publication of AT351189B publication Critical patent/AT351189B/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C07D307/935Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D309/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/10Oxygen atoms
    • C07D309/12Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D319/00Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/101,4-Dioxanes; Hydrogenated 1,4-dioxanes
    • C07D319/121,4-Dioxanes; Hydrogenated 1,4-dioxanes not condensed with other rings

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT204576A 1975-03-21 1976-03-19 Verfahren zur herstellung von neuen fluor- prostaglandinen AT351189B (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT149375 1975-03-21
IT21493/75A IT1049373B (it) 1975-03-21 1975-03-21 Fluoro prostaglandine

Publications (2)

Publication Number Publication Date
ATA204576A true ATA204576A (de) 1978-12-15
AT351189B AT351189B (de) 1979-07-10

Family

ID=26325130

Family Applications (1)

Application Number Title Priority Date Filing Date
AT204576A AT351189B (de) 1975-03-21 1976-03-19 Verfahren zur herstellung von neuen fluor- prostaglandinen

Country Status (10)

Country Link
US (4) US4338332A (de)
AT (1) AT351189B (de)
AU (1) AU501803B2 (de)
BE (1) BE839789A (de)
CA (1) CA1103663A (de)
CH (2) CH629769A5 (de)
DE (1) DE2611788C2 (de)
FR (1) FR2313029A1 (de)
GB (1) GB1493557A (de)
NL (1) NL7602862A (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL51877A (en) * 1976-06-01 1981-09-13 Carlo Erba Sa -nor-16-benzyl or phenoxy-13,14-dehydro-prostaglandins and process for their preparation
DE3004795A1 (de) * 1980-02-07 1981-08-13 Schering Ag Berlin Und Bergkamen, 1000 Berlin Neue prostacyclinderivate, ihre herstellung und anwendung
GB8324004D0 (en) * 1983-09-07 1983-10-12 Erba Farmitalia 16-fluoro-16 17-didehydro prostanoids
SU1256394A1 (ru) * 1984-04-24 1987-06-07 Институт Органического Синтеза Ан Латвсср Производные 15( @ + @ )-фтор-11,15-дидезоксипростагландина @ ,обладающие антиагрегационной активностью
EP0597095B1 (de) * 1991-04-22 1996-10-30 Taisho Pharmaceutical Co. Ltd Prostaglandin e1-analoge
AU5355498A (en) * 1996-11-12 1998-06-03 Alcon Laboratories, Inc. 15-fluoro prostaglandins as ocular hypotensives

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3959346A (en) * 1969-03-14 1976-05-25 The Upjohn Company Racemic prostaglandins of the 2-series and analogs thereof
GB1425962A (en) * 1972-04-13 1976-02-25 Erba Carlo Spa Lactols and lactones
DE2317019A1 (de) * 1972-04-27 1973-11-08 Upjohn Co Neue 4,5-didehydro-prostaglandine
US3862979A (en) * 1972-06-15 1975-01-28 Erba Carlo Spa 9-desoxy-prosta-5,9(10),13-trienoic acid derivatives
US3933899A (en) * 1972-10-30 1976-01-20 The Upjohn Company PGE2 -oxa-phenylene compounds
US3914282A (en) * 1973-01-16 1975-10-21 Upjohn Co Prostaglandin E{HD 1{B , F{HD 1{B , and A{HD 1 {B analogs
JPS5720305B2 (de) * 1973-02-28 1982-04-27
US3962293A (en) * 1973-07-20 1976-06-08 The Upjohn Company 13,14-Dihydro-16-fluoro prostaglandin F1
US3932463A (en) * 1974-06-03 1976-01-13 American Cyanamid Company 11-Deoxy-13-dihydro-prostaglandin-9-ketals
IT1053781B (it) * 1974-09-25 1981-10-10 Erba C S P A Ora Farmitalia Omega nor cicloalcil 13.14 deidro prostaglandine
IT1037126B (it) * 1975-03-14 1979-11-10 Erba Carlo Spa 13.4 deidro ii desossi prosta glandine

Also Published As

Publication number Publication date
US4338249A (en) 1982-07-06
AU501803B2 (en) 1979-06-28
AU1191776A (en) 1977-09-15
CH623570A5 (de) 1981-06-15
BE839789A (fr) 1976-07-16
US4320143A (en) 1982-03-16
CH629769A5 (de) 1982-05-14
GB1493557A (en) 1977-11-30
DE2611788A1 (de) 1976-09-30
NL7602862A (nl) 1976-09-23
FR2313029B1 (de) 1979-09-21
US4229585A (en) 1980-10-21
US4338332A (en) 1982-07-06
AT351189B (de) 1979-07-10
DE2611788C2 (de) 1986-03-27
CA1103663A (en) 1981-06-23
FR2313029A1 (fr) 1976-12-31

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Legal Events

Date Code Title Description
ELJ Ceased due to non-payment of the annual fee
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties