AT96964B - Process for improving the taste of the alkali salts of dialkylbarbituric acids. - Google Patents
Process for improving the taste of the alkali salts of dialkylbarbituric acids.Info
- Publication number
- AT96964B AT96964B AT96964DA AT96964B AT 96964 B AT96964 B AT 96964B AT 96964D A AT96964D A AT 96964DA AT 96964 B AT96964 B AT 96964B
- Authority
- AT
- Austria
- Prior art keywords
- taste
- improving
- alkali salts
- dialkylbarbituric acids
- dialkylbarbituric
- Prior art date
Links
Landscapes
- Medicinal Preparation (AREA)
Description
<Desc/Clms Page number 1>
Verfahren zur Geschmacitsyerbesserung der Alkalisalze der Dialkylbarbitursäm'en.
Es wurde gefunden, dass man den bitteren Geschmack der in der Therapie eine grosse Rolle spielenden Alkalisalze der Dialkylbarbitursäuren durch Verarbeiten derselben mit Dinatriumphosphat zu Mischungen
EMI1.1
Geschmack dieser Substanzen, wie auch den Salzgeschmack des Zusatzes fast völlig auszulöschen bzw. den bitteren Geschmack vollständig oder zum Teil zu unterdrücken. Über die theoretische Grundlage dieser auf sinnesphysiologischem Gebiet liegenden Beobachtungen, die noch gänzlich unerforscht sind, lässt sich keinerlei Erklärung geben.
Beispiel 1 : Gleiche Gewichtsmengen diäthylbarbitursaures Natrium und wasserfreies Dinatriumphosphat werden in Wasser gelöst. Die Lösung hat den widerlich laugig-bitteren Geschmack des diäthyl- barbitursauren Natriums fast vollständig verloren und kann in dieser Form direkte Anwendung finden.
Beispiel 2 : Die in Beispiel 1 angewandten Komponenten werden in trockenem Zustande innig miteinander vermischt und die Mischung als solche oder nach Zusatz von etwas Stärke zu Tabletten gepresst.
**WARNUNG** Ende DESC Feld kannt Anfang CLMS uberlappen**.
<Desc / Clms Page number 1>
Process for improving the taste of the alkali salts of dialkylbarbiturates.
It has been found that the bitter taste of the alkali salts of dialkylbarbituric acids, which play a major role in therapy, can be obtained by processing them with disodium phosphate to form mixtures
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To extinguish the taste of these substances, as well as the salty taste of the additive, or to suppress the bitter taste completely or partially. No explanation can be given about the theoretical basis of these sensory-physiological observations, which are still completely unexplored.
Example 1: Equal amounts by weight of sodium diethylbarbiturate and anhydrous disodium phosphate are dissolved in water. The solution has almost completely lost the disgusting lye-bitter taste of diethyl barbiturate and can be used directly in this form.
Example 2: The components used in Example 1 are intimately mixed with one another in the dry state and the mixture as such or after adding some starch is pressed into tablets.
** WARNING ** End of DESC field may overlap beginning of CLMS **.
Claims (1)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE96964X | 1922-04-11 |
Publications (1)
Publication Number | Publication Date |
---|---|
AT96964B true AT96964B (en) | 1924-05-26 |
Family
ID=5646101
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT96964D AT96964B (en) | 1922-04-11 | 1923-02-26 | Process for improving the taste of the alkali salts of dialkylbarbituric acids. |
Country Status (1)
Country | Link |
---|---|
AT (1) | AT96964B (en) |
-
1923
- 1923-02-26 AT AT96964D patent/AT96964B/en active
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