AT381091B - Verfahren zur herstellung von neuen ergolinderivaten - Google Patents

Verfahren zur herstellung von neuen ergolinderivaten

Info

Publication number
AT381091B
AT381091B AT0399682A AT399682A AT381091B AT 381091 B AT381091 B AT 381091B AT 0399682 A AT0399682 A AT 0399682A AT 399682 A AT399682 A AT 399682A AT 381091 B AT381091 B AT 381091B
Authority
AT
Austria
Prior art keywords
producing new
derivatives
ergol derivatives
new ergol
producing
Prior art date
Application number
AT0399682A
Other languages
English (en)
Other versions
ATA399682A (de
Inventor
Luigi Bernardi
Aldemio Temperilli
Daniela Ruggieri
Giuliana Arcari
Patricia Salvati
Original Assignee
Erba Farmitalia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Erba Farmitalia filed Critical Erba Farmitalia
Publication of ATA399682A publication Critical patent/ATA399682A/de
Application granted granted Critical
Publication of AT381091B publication Critical patent/AT381091B/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/02—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hydrocarbon or substituted hydrocarbon radicals, attached in position 8
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/10—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hetero atoms directly attached in position 8
    • C07D457/12—Nitrogen atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT0399682A 1981-11-06 1982-11-02 Verfahren zur herstellung von neuen ergolinderivaten AT381091B (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8133631 1981-11-06

Publications (2)

Publication Number Publication Date
ATA399682A ATA399682A (de) 1986-01-15
AT381091B true AT381091B (de) 1986-08-25

Family

ID=10525712

Family Applications (1)

Application Number Title Priority Date Filing Date
AT0399682A AT381091B (de) 1981-11-06 1982-11-02 Verfahren zur herstellung von neuen ergolinderivaten

Country Status (21)

Country Link
US (1) US4500712A (de)
JP (1) JPS5885886A (de)
AT (1) AT381091B (de)
AU (1) AU553903B2 (de)
BE (1) BE894927A (de)
CA (1) CA1191841A (de)
CH (1) CH650506A5 (de)
CS (1) CS232000B2 (de)
DE (1) DE3240727A1 (de)
DK (1) DK494882A (de)
FI (1) FI73214C (de)
FR (1) FR2516083A1 (de)
GB (1) GB2112382B (de)
GR (1) GR77055B (de)
IE (1) IE54327B1 (de)
IL (1) IL67155A (de)
IT (1) IT1205272B (de)
NL (1) NL8204225A (de)
SE (1) SE452884B (de)
SU (1) SU1189347A3 (de)
ZA (1) ZA828095B (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3151912A1 (de) * 1981-12-23 1983-06-30 Schering Ag, 1000 Berlin Und 4619 Bergkamen Neue ergolin-aminoderivate, verfahren zu ihrer herstellung und deren verwendung als arzneimittel
PH21123A (en) * 1983-04-28 1987-07-27 Erba Farmitalia Ergoline derivatives
DE3413657A1 (de) * 1984-04-09 1985-10-17 Schering AG, 1000 Berlin und 4709 Bergkamen Neue ergoline
ATE107647T1 (de) * 1984-04-09 1994-07-15 Schering Ag 2-substituierte ergolin-derivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel.
GB2173189B (en) * 1985-02-21 1988-04-27 Maruko Pharmaceutical Co Ergoline derivatives and salts thereof and pharmaceutical compositions thereof
GB8515528D0 (en) * 1985-06-19 1985-07-24 Erba Farmitalia Ergoline derivatives
DE3528584A1 (de) * 1985-08-06 1987-02-19 Schering Ag Neue 1-alkyl-ergolin-thioharnstoffderivate
DE3533672A1 (de) * 1985-09-19 1987-03-26 Schering Ag Neue 12- und 13-substituierte ergolinderivate
DE3535930A1 (de) * 1985-10-04 1987-04-09 Schering Ag Neue 2-substituierte ergolinderivate
DE19832191A1 (de) * 1998-07-17 2000-01-27 Knoell Hans Forschung Ev Neuartige Ergolinamin-Derivate und ihre Verwendung
ES2325880T3 (es) 2001-06-08 2009-09-23 Ipsen Pharma Analogos quimericos de somatostatina-dopamina.
TW200637559A (en) * 2005-03-29 2006-11-01 Shionogi & Co 3-propenylcefem derivative
TWI523863B (zh) 2012-11-01 2016-03-01 艾普森藥品公司 體抑素－多巴胺嵌合體類似物
US9777039B2 (en) 2012-11-01 2017-10-03 Ipsen Pharma S.A.S. Somatostatin analogs and dimers thereof

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DD138979A1 (de) * 1978-09-27 1979-12-05 Karlheinz Seifert Verfahren zur herstellung von acylthioharnstoffen mit ergolinstruktur

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3238211A (en) * 1966-03-01 Derhvatives of g-methyl and i,g-dimethyl ergolhne
AT258479B (de) * 1961-05-29 1967-11-27 Farmaceutici Italia Verfahren zur Herstellung von neuen Verbindungen aus der Klasse des D-6-Methyl- (und -1,6-Dimethyl)-8-amino-methyl-ergolins I
GB1005880A (en) * 1961-11-10 1965-09-29 Sandoz Ag Ergolene and ergoline derivatives
NL6710210A (de) * 1966-07-29 1968-01-30
CH507248A (de) * 1967-03-16 1971-05-15 Spofa Vereinigte Pharma Werke Verfahren zur Herstellung von D-6-Methylergolin(I)ylessigsäure
BR6915443D0 (pt) * 1969-07-18 1973-03-13 Farmaceutici Italia Processo para a preparacao de derivados de ergolina
US3966941A (en) * 1970-09-23 1976-06-29 Spofa United Pharmaceutical Works Composition for preventing lactation or pregnancy in mammals and the method for using the same
SE393615B (sv) * 1971-05-19 1977-05-16 Sandoz Ag Forfarande for framstellning av 6-metyl-8 beta-ureidometyl-ergolener
NL7416120A (nl) * 1973-12-21 1975-06-24 Farmaceutici Italia Werkwijze voor het bereiden van pyrimidinoami- nomethylergolinederivaten.
US3996228A (en) * 1973-12-21 1976-12-07 Societa' Farmaceutici Italia S.P.A. Pyrimidinoaminoethyl ergoline derivatives
GB1573621A (en) * 1976-01-02 1980-08-28 Sandoz Ltd Acylated 6-methyl-8a-amino-ergoline i compounds
DE2656344A1 (de) * 1975-12-23 1977-07-07 Sandoz Ag Ergolinderivate, ihre verwendung und herstellung
HU178396B (en) * 1978-03-20 1982-04-28 Vianova Kunstharz Ag Process for producing new 8-beta-hydrazion-methyl-ergoline-and -ergolene derivatives
US4201862A (en) * 1979-03-16 1980-05-06 Eli Lilly And Company 2-Azaergolines and 2-aza-8(or 9)-ergolenes
DE3129714A1 (de) * 1981-07-23 1983-02-10 Schering Ag, 1000 Berlin Und 4619 Bergkamen Anti-psychotikum

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DD138979A1 (de) * 1978-09-27 1979-12-05 Karlheinz Seifert Verfahren zur herstellung von acylthioharnstoffen mit ergolinstruktur

Also Published As

Publication number Publication date
ATA399682A (de) 1986-01-15
DK494882A (da) 1983-05-07
SE8206282L (sv) 1983-05-07
FI73214B (fi) 1987-05-29
IT8224077A0 (it) 1982-11-04
FI823727L (fi) 1983-05-07
FI823727A0 (fi) 1982-11-01
IE54327B1 (en) 1989-08-30
SE452884B (sv) 1987-12-21
SU1189347A3 (ru) 1985-10-30
SE8206282D0 (sv) 1982-11-04
CA1191841A (en) 1985-08-13
GB2112382B (en) 1985-03-06
IL67155A0 (en) 1983-03-31
US4500712A (en) 1985-02-19
FR2516083B1 (de) 1984-05-25
GR77055B (de) 1984-09-05
AU553903B2 (en) 1986-07-31
IE822614L (en) 1983-05-06
FI73214C (fi) 1987-09-10
FR2516083A1 (fr) 1983-05-13
GB2112382A (en) 1983-07-20
CS775282A2 (en) 1984-01-16
JPS628433B2 (de) 1987-02-23
JPS5885886A (ja) 1983-05-23
AU9009082A (en) 1983-05-12
CH650506A5 (de) 1985-07-31
BE894927A (fr) 1983-05-05
ZA828095B (en) 1983-09-28
CS232000B2 (en) 1985-01-16
DE3240727A1 (de) 1983-05-19
IL67155A (en) 1985-07-31
IT1205272B (it) 1989-03-15
NL8204225A (nl) 1983-06-01

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Legal Events

Date Code Title Description
ELJ Ceased due to non-payment of the annual fee
ELJ Ceased due to non-payment of the annual fee