AT358040B - METHOD FOR PRODUCING THE NEW (R, S) -CIS- -ALPHA- (3- (2,6-DIMETHYLPIPERIDINO) -PROPYL) ALPHA -PHENYL-2-PYRIDYLMETHANOLS, ITS R- AND S- ISOMERIC AND ITS ACID ADDITION - Google Patents

METHOD FOR PRODUCING THE NEW (R, S) -CIS- -ALPHA- (3- (2,6-DIMETHYLPIPERIDINO) -PROPYL) ALPHA -PHENYL-2-PYRIDYLMETHANOLS, ITS R- AND S- ISOMERIC AND ITS ACID ADDITION

Info

Publication number
AT358040B
AT358040B AT117078A AT117078A AT358040B AT 358040 B AT358040 B AT 358040B AT 117078 A AT117078 A AT 117078A AT 117078 A AT117078 A AT 117078A AT 358040 B AT358040 B AT 358040B
Authority
AT
Austria
Prior art keywords
alpha
pyridylmethanols
dimethylpiperidino
isomeric
cis
Prior art date
Application number
AT117078A
Other languages
German (de)
Other versions
ATA117078A (en
Original Assignee
Parke Davis & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/772,203 external-priority patent/US4112103A/en
Application filed by Parke Davis & Co filed Critical Parke Davis & Co
Publication of ATA117078A publication Critical patent/ATA117078A/en
Application granted granted Critical
Publication of AT358040B publication Critical patent/AT358040B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182—Radicals derived from carboxylic acids
    • C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D317/16—Radicals substituted by halogen atoms or nitro radicals

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
AT117078A 1977-02-25 1978-02-17 METHOD FOR PRODUCING THE NEW (R, S) -CIS- -ALPHA- (3- (2,6-DIMETHYLPIPERIDINO) -PROPYL) ALPHA -PHENYL-2-PYRIDYLMETHANOLS, ITS R- AND S- ISOMERIC AND ITS ACID ADDITION AT358040B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/772,203 US4112103A (en) 1976-04-15 1977-02-25 Antiarrhythmic (+,-)-cis-α-[3-(2,6-dimethyl-1-piperidinyl)propyl]-α-phenyl-2-pyridinemethanols

Publications (2)

Publication Number Publication Date
ATA117078A ATA117078A (en) 1980-01-15
AT358040B true AT358040B (en) 1980-08-11

Family

ID=25094280

Family Applications (1)

Application Number Title Priority Date Filing Date
AT117078A AT358040B (en) 1977-02-25 1978-02-17 METHOD FOR PRODUCING THE NEW (R, S) -CIS- -ALPHA- (3- (2,6-DIMETHYLPIPERIDINO) -PROPYL) ALPHA -PHENYL-2-PYRIDYLMETHANOLS, ITS R- AND S- ISOMERIC AND ITS ACID ADDITION

Country Status (11)

Country Link
JP (1) JPS53105479A (en)
AT (1) AT358040B (en)
BE (1) BE864033A (en)
CA (1) CA1096382A (en)
CH (1) CH635095A5 (en)
DE (1) DE2806654A1 (en)
DK (1) DK143229C (en)
ES (1) ES467100A1 (en)
FR (1) FR2381761A1 (en)
GB (1) GB1581096A (en)
PH (1) PH13125A (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2818914B2 (en) * 1991-04-05 1998-10-30 シャープ株式会社 Multipurpose steam generator

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE757408A (en) * 1969-10-13 1971-04-13 Thomae Gmbh Dr K NEW TERTIARY BUTANOLS WITH BASIC CONSTITUENTS

Also Published As

Publication number Publication date
DK143229B (en) 1981-07-27
ATA117078A (en) 1980-01-15
FR2381761A1 (en) 1978-09-22
PH13125A (en) 1979-12-12
FR2381761B1 (en) 1982-03-26
GB1581096A (en) 1980-12-10
DK73278A (en) 1978-08-26
BE864033A (en) 1978-06-16
JPS53105479A (en) 1978-09-13
CA1096382A (en) 1981-02-24
DE2806654A1 (en) 1978-08-31
DK143229C (en) 1981-11-30
DE2806654C2 (en) 1987-07-16
JPS6257632B2 (en) 1987-12-02
CH635095A5 (en) 1983-03-15
ES467100A1 (en) 1978-11-01

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Legal Events

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ELJ Ceased due to non-payment of the annual fee
REN Ceased due to non-payment of the annual fee