AT309403B - Verfahren zur Herstellung der optischen Enantiomeren von α<1>-tert.Butylaminomethyl-4-hydroxy-m-xylylen-α<1>,α<3>-diol und deren Säureadditionssalze - Google Patents

Verfahren zur Herstellung der optischen Enantiomeren von α<1>-tert.Butylaminomethyl-4-hydroxy-m-xylylen-α<1>,α<3>-diol und deren Säureadditionssalze

Info

Publication number
AT309403B
AT309403B AT510171A AT510171A AT309403B AT 309403 B AT309403 B AT 309403B AT 510171 A AT510171 A AT 510171A AT 510171 A AT510171 A AT 510171A AT 309403 B AT309403 B AT 309403B
Authority
AT
Austria
Prior art keywords
butylaminomethyl
xylylene
diol
tert
hydroxy
Prior art date
Application number
AT510171A
Other languages
German (de)
English (en)
Inventor
David Middlemiss
Original Assignee
Allen & Hanburys Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Allen & Hanburys Ltd filed Critical Allen & Hanburys Ltd
Application granted granted Critical
Publication of AT309403B publication Critical patent/AT309403B/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C213/10Separation; Purification; Stabilisation; Use of additives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C213/02Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions involving the formation of amino groups from compounds containing hydroxy groups or etherified or esterified hydroxy groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C213/08Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions not involving the formation of amino groups, hydroxy groups or etherified or esterified hydroxy groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07Optical isomers
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/12Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14The ring being saturated
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT510171A 1970-06-17 1971-06-14 Verfahren zur Herstellung der optischen Enantiomeren von α<1>-tert.Butylaminomethyl-4-hydroxy-m-xylylen-α<1>,α<3>-diol und deren Säureadditionssalze AT309403B (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB29367/70A GB1298494A (en) 1970-06-17 1970-06-17 Phenylethanolamine derivatives

Publications (1)

Publication Number Publication Date
AT309403B true AT309403B (de) 1973-08-27

Family

ID=10290419

Family Applications (1)

Application Number Title Priority Date Filing Date
AT510171A AT309403B (de) 1970-06-17 1971-06-14 Verfahren zur Herstellung der optischen Enantiomeren von α<1>-tert.Butylaminomethyl-4-hydroxy-m-xylylen-α<1>,α<3>-diol und deren Säureadditionssalze

Country Status (14)

Country Link
JP (1) JPS5525181B1 (da)
AT (1) AT309403B (da)
BE (1) BE768120A (da)
CA (1) CA984854A (da)
CH (1) CH553746A (da)
DE (1) DE2128258C2 (da)
DK (1) DK130920B (da)
ES (1) ES392008A1 (da)
FR (1) FR2100772B1 (da)
GB (1) GB1298494A (da)
IL (2) IL43177A (da)
NL (1) NL173635C (da)
YU (1) YU35338B (da)
ZA (1) ZA713298B (da)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0259159A3 (en) * 1986-09-05 1989-08-09 Schering Corporation Method for the preparation of alpha1- [[(1,1-Dimethylethyl) amino] methyl]-4-hydroxy-1,3-benzenedimethanol, and intermediates used in its preparation
US4952729A (en) * 1986-09-05 1990-08-28 Schering-Plough Corp. Intermediates in the preparation of alpha1(((1,1-dimethylethyl) amino) methyl)-4-hydroxy-1,3-benzenedimethanol
WO1991009596A1 (en) * 1990-01-05 1991-07-11 Sepracor, Inc. Optically pure r(-) albuterol for treating asthma
US5362755A (en) * 1990-01-05 1994-11-08 Sepracor, Inc. Method for treating asthma using optically pure (R)-albuterol
ZA994264B (en) 1998-07-01 2000-01-25 Warner Lambert Co Stereoisomers with high affinity for adrenergic receptors.
US7232837B2 (en) 1999-06-29 2007-06-19 Mcneil-Ppc, Inc. Stereoisomers with high affinity for adrenergic receptors
EP1747189A1 (en) 2004-05-20 2007-01-31 Teva Pharmaceutical Fine Chemicals S.R.L. Preparation of levalbuterol hydrochloride
EP1832572A1 (en) * 2006-03-08 2007-09-12 Stirling Products Limited Process for the enantiomeric enrichment of salbutamol and salbutamol precursors
EP1935872A1 (en) * 2006-12-11 2008-06-25 Stirling Products Limited Process for obtaining the R-enantiomer of salbutamol
US9784726B2 (en) 2013-01-08 2017-10-10 Atrogi Ab Screening method, a kit, a method of treatment and a compound for use in a method of treatment
GB201714740D0 (en) 2017-09-13 2017-10-25 Atrogi Ab New compounds and uses
GB201714745D0 (en) 2017-09-13 2017-10-25 Atrogi Ab New compounds and uses
GB201714734D0 (en) 2017-09-13 2017-10-25 Atrogi Ab New compounds and uses
GB201714736D0 (en) 2017-09-13 2017-10-25 Atrogi Ab New compounds and uses
GB202205895D0 (en) 2022-04-22 2022-06-08 Atrogi Ab New medical uses

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1200886A (en) * 1966-09-23 1970-08-05 Allen & Hanburys Ltd Phenylaminoethanol derivatives

Also Published As

Publication number Publication date
ES392008A1 (es) 1974-08-01
CH553746A (de) 1974-09-13
YU35338B (en) 1980-12-31
NL7108368A (da) 1971-12-21
DE2128258A1 (de) 1971-12-23
JPS5525181B1 (da) 1980-07-04
DE2128258C2 (de) 1983-08-11
IL43177A (en) 1974-01-14
NL173635B (nl) 1983-09-16
ZA713298B (en) 1972-01-26
FR2100772B1 (da) 1975-06-06
YU151671A (en) 1980-06-30
IL36927A (en) 1974-01-14
DK130920C (da) 1975-10-06
FR2100772A1 (da) 1972-03-24
GB1298494A (en) 1972-12-06
CA984854A (en) 1976-03-02
DK130920B (da) 1975-05-05
IL36927A0 (en) 1971-07-28
BE768120A (fr) 1971-12-06
NL173635C (nl) 1984-02-16

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