AR241590A1 - Procedimiento para elaborar 1-fenil-3-azabiciclo(3.1.0)hexan-2,4-dionas y sus sales. - Google Patents

Procedimiento para elaborar 1-fenil-3-azabiciclo(3.1.0)hexan-2,4-dionas y sus sales.

Info

Publication number
AR241590A1
AR241590A1 AR83295196A AR29519683A AR241590A1 AR 241590 A1 AR241590 A1 AR 241590A1 AR 83295196 A AR83295196 A AR 83295196A AR 29519683 A AR29519683 A AR 29519683A AR 241590 A1 AR241590 A1 AR 241590A1
Authority
AR
Argentina
Prior art keywords
salts
phenyl
procedure
alkyl
azabicyclic
Prior art date
Application number
AR83295196A
Other languages
English (en)
Original Assignee
Ciba Geigy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy filed Critical Ciba Geigy
Application granted granted Critical
Publication of AR241590A1 publication Critical patent/AR241590A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/52—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring condensed with a ring other than six-membered
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/49—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups
    • C07C205/55—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups having nitro groups or carboxyl groups bound to carbon atoms of rings other than six-membered aromatic rings of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/49—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups
    • C07C205/56—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups having nitro groups bound to carbon atoms of six-membered aromatic rings and carboxyl groups bound to acyclic carbon atoms of the carbon skeleton

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Indole Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Steroid Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

PROCEDIMIENTO PARA LA ELABORACION DE COMPUESTOS DE 1-FENIL-3- AZABICICLO(3.1.0.)HEXAN-2,4-DIONAS DE FORMULA (I), DONDE R1 ES H, R2 ES H, ALCANOILO O -ALCANSULFONILO Y R3 ES H O R1 ES -ALQUILO, -ALQUENILO, - CICLOALQUIL-ALQUILO O BENCILO; R2 ES H, -ALQUILO, -ALCANOILO O - ALCANSULFONILO Y R3 ES H O -ALQUILO, Y SUS SALES. UN COMPUESTO DE FORMULA (II), DONDE R1 TIENE LOS VALORES INDICADOS, SEREDUCE EL GRUPO NO2 CON UN REDUCTOR ELEGIDO ENTRE H Y SALES DE ESTANO (II)- O HIERRO
AR83295196A 1982-12-21 1983-12-21 Procedimiento para elaborar 1-fenil-3-azabiciclo(3.1.0)hexan-2,4-dionas y sus sales. AR241590A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH745082 1982-12-21

Publications (1)

Publication Number Publication Date
AR241590A1 true AR241590A1 (es) 1992-09-30

Family

ID=4325317

Family Applications (2)

Application Number Title Priority Date Filing Date
AR83295196A AR241590A1 (es) 1982-12-21 1983-12-21 Procedimiento para elaborar 1-fenil-3-azabiciclo(3.1.0)hexan-2,4-dionas y sus sales.
AR86303163A AR241421A1 (es) 1982-12-21 1986-02-18 Procedimiento para la elaboracion de azacicloalcanos-sustitutivos.

Family Applications After (1)

Application Number Title Priority Date Filing Date
AR86303163A AR241421A1 (es) 1982-12-21 1986-02-18 Procedimiento para la elaboracion de azacicloalcanos-sustitutivos.

Country Status (23)

Country Link
US (1) US4839379A (es)
EP (1) EP0114033B1 (es)
JP (1) JPS59118748A (es)
KR (1) KR900009007B1 (es)
AR (2) AR241590A1 (es)
AT (1) ATE37871T1 (es)
AU (1) AU565914B2 (es)
CA (1) CA1208649A (es)
DD (1) DD222306A5 (es)
DE (1) DE3378208D1 (es)
DK (1) DK165977C (es)
ES (3) ES528179A0 (es)
FI (1) FI79838C (es)
GR (1) GR81359B (es)
HK (1) HK24291A (es)
HU (1) HU192836B (es)
IE (1) IE56421B1 (es)
IL (1) IL70478A (es)
NO (1) NO163529C (es)
NZ (1) NZ206654A (es)
PH (1) PH22052A (es)
PT (1) PT77857B (es)
ZA (1) ZA839437B (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0166692B1 (de) * 1984-06-20 1990-07-11 Ciba-Geigy Ag Substituierte Azabicycloheptane, ihre Verwendung, pharmazeutische Präparate, welche diese Verbindungen enthalten, und Verfahren zur Herstellung dieser Verbindungen
CH683151A5 (de) * 1991-04-24 1994-01-31 Ciba Geigy Ag Antikonzeption bei weiblichen Primaten ohne Beeinflussung des menstruellen Zyklus.
WO1993007141A1 (en) * 1991-10-11 1993-04-15 Smithkline Beecham Corporation Heterocyclic 3-phenylpyrrolidin-2-ones, their preparation and use for the manufacture of a medicament for inhibiting tumor necrosis factor production
US5511916A (en) * 1991-12-06 1996-04-30 Aldon Pattern, Inc. Shipping container for dunnage
MX2007000851A (es) * 2004-07-22 2007-03-26 Wyeth Corp Procedimiento para el tratamiento de trastornos y dolencias del sistema nervioso.
US20060019966A1 (en) * 2004-07-22 2006-01-26 Wyeth Method for treating nervous system disorders and conditions
CA2574310A1 (en) * 2004-07-22 2006-02-02 Wyeth Method for treating nervous system disorders and conditions
US20070021488A1 (en) * 2005-07-21 2007-01-25 Wyeth Method for treating nervous system disorders and conditions

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE548074A (es) *
US2673205A (en) * 1951-02-13 1954-03-23 Ciba Pharm Prod Inc 3-disubstituted dioxopiperidines and the manufacture thereof
US2848455A (en) * 1955-07-18 1958-08-19 Ciba Pharm Prod Inc Alpha-(p-amino-phenyl)-alpha-lower alkyl glutarimides
GB1015618A (en) * 1962-04-10 1966-01-05 Aspro Nicholas Ltd Glutarimide therapeutic compositions
US3166571A (en) * 1962-06-06 1965-01-19 American Cyanamid Co 1-phenyl-1, 2-cyclopropane dicarboximides
US3621012A (en) * 1969-08-18 1971-11-16 Union Carbide Corp Oxidation of lactams to cyclic imides
US4164404A (en) * 1973-06-25 1979-08-14 American Cyanamid Company Dithiindicarboximide, dithiolanedicarboximide, thiapyrandicarboximide and pyrandicarboximide derivatives as plant growth regulants
US4131611A (en) * 1975-07-31 1978-12-26 American Cyanamid Company Azabicyclohexanes
US4231935A (en) * 1975-07-31 1980-11-04 American Cyanamid Company 1-Phenyl-3-azabicyclo[3.1.0]hexanes
IL65843A (en) * 1977-08-11 1986-12-31 American Cyanamid Co Pharmaceutical compositions for the treatment of depression containing 3-aza-bicyclo(3.1.0)hexane derivatives and certain novel compounds of this type
US4289762A (en) * 1980-06-27 1981-09-15 Merrell Dow Pharmaceuticals Inc. 10-(1,2-Propadienyl) steroids as irreversible aromatase inhibitors
US4322416A (en) * 1980-06-27 1982-03-30 Merrell Dow Pharmaceuticals Inc. 10-Alkynyl steroids
DE3121153A1 (de) * 1981-05-22 1982-12-09 Schering Ag, 1000 Berlin Und 4619 Bergkamen "verwendung von aromatase-hemmern zur prophylaxe und therapie der prostatahyperplasie"
US4435419A (en) * 1981-07-01 1984-03-06 American Cyanamid Company Method of treating depression using azabicyclohexanes
EP0166692B1 (de) * 1984-06-20 1990-07-11 Ciba-Geigy Ag Substituierte Azabicycloheptane, ihre Verwendung, pharmazeutische Präparate, welche diese Verbindungen enthalten, und Verfahren zur Herstellung dieser Verbindungen

Also Published As

Publication number Publication date
GR81359B (es) 1984-12-11
US4839379A (en) 1989-06-13
NZ206654A (en) 1987-01-23
ES8603832A1 (es) 1986-01-01
ES8607941A1 (es) 1986-06-01
IL70478A (en) 1987-09-16
AU565914B2 (en) 1987-10-01
HK24291A (en) 1991-04-04
JPS59118748A (ja) 1984-07-09
ES543431A0 (es) 1986-06-01
IL70478A0 (en) 1984-03-30
ZA839437B (en) 1984-07-25
EP0114033B1 (de) 1988-10-12
NO834710L (no) 1984-06-22
DK586283D0 (da) 1983-12-20
PH22052A (en) 1988-05-13
EP0114033A1 (de) 1984-07-25
DK586283A (da) 1984-06-22
ATE37871T1 (de) 1988-10-15
HU192836B (en) 1987-07-28
ES8601130A1 (es) 1985-11-01
IE833006L (en) 1984-06-21
CA1208649A (en) 1986-07-29
IE56421B1 (en) 1991-07-31
PT77857B (de) 1986-04-21
NO163529B (no) 1990-03-05
FI79838B (fi) 1989-11-30
HUT34444A (en) 1985-03-28
FI834663A0 (fi) 1983-12-19
FI79838C (fi) 1990-03-12
NO163529C (no) 1990-06-13
FI834663A (fi) 1984-06-22
ES543430A0 (es) 1986-01-01
KR840006966A (ko) 1984-12-04
ES528179A0 (es) 1985-11-01
DE3378208D1 (en) 1988-11-17
PT77857A (de) 1984-01-01
AU2270483A (en) 1984-06-28
AR241421A1 (es) 1992-07-31
KR900009007B1 (ko) 1990-12-17
DK165977B (da) 1993-02-22
DD222306A5 (de) 1985-05-15
DK165977C (da) 1993-07-26

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