AR228596A1 - 9-(2-cianoetil)-9-carbamoil-fluorenos,exentos de aplicaciones terapeuticas y utiles como intermediarios para preparar 9-carbamoil-9-amino-propil-fluorenos - Google Patents

9-(2-cianoetil)-9-carbamoil-fluorenos,exentos de aplicaciones terapeuticas y utiles como intermediarios para preparar 9-carbamoil-9-amino-propil-fluorenos

Info

Publication number: AR228596A1
Authority: AR; Argentina
Prior art keywords: fluorenos; carbamoil; cianoetil; propil; intermediaries
Prior art date: 1980-04-17

Application number

AR284966A

Other languages

English (en)

Original Assignee

Lilly Co Eli

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1980-04-17

Filing date

1981-04-14

Publication date

1983-03-30

1981-04-14 Application filed by Lilly Co Eli filed Critical Lilly Co Eli

1983-03-30 Application granted granted Critical

1983-03-30 Publication of AR228596A1 publication Critical patent/AR228596A1/es

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C253/00—Preparation of carboxylic acid nitriles
- C07C253/30—Preparation of carboxylic acid nitriles by reactions not involving the formation of cyano groups
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
- C07C255/45—Carboxylic acid nitriles having cyano groups bound to carbon atoms of rings other than six-membered aromatic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
- C07C255/01—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms
- C07C255/24—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms containing cyano groups and singly-bound nitrogen atoms, not being further bound to other hetero atoms, bound to the same saturated acyclic carbon skeleton
- C07C255/29—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms containing cyano groups and singly-bound nitrogen atoms, not being further bound to other hetero atoms, bound to the same saturated acyclic carbon skeleton containing cyano groups and acylated amino groups bound to the carbon skeleton
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2603/00—Systems containing at least three condensed rings
- C07C2603/02—Ortho- or ortho- and peri-condensed systems
- C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
- C07C2603/06—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members
- C07C2603/10—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings
- C07C2603/12—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings only one five-membered ring
- C07C2603/18—Fluorenes; Hydrogenated fluorenes

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
General Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Heart & Thoracic Surgery (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Cardiology (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Bioinformatics & Cheminformatics (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

AR284966A 1980-04-17 1981-04-14 9-(2-cianoetil)-9-carbamoil-fluorenos,exentos de aplicaciones terapeuticas y utiles como intermediarios para preparar 9-carbamoil-9-amino-propil-fluorenos AR228596A1 (es)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US06/141,229 US4282170A (en)	1980-04-17	1980-04-17	9-Carbamoyl-9-(2-cyanoethyl)fluorenes

Publications (1)

Publication Number	Publication Date
AR228596A1 true AR228596A1 (es)	1983-03-30

Family

ID=22494758

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AR284966A AR228596A1 (es)	1980-04-17	1981-04-14	9-(2-cianoetil)-9-carbamoil-fluorenos,exentos de aplicaciones terapeuticas y utiles como intermediarios para preparar 9-carbamoil-9-amino-propil-fluorenos

Country Status (26)

Country	Link
US (1)	US4282170A (es)
EP (1)	EP0038676B1 (es)
JP (2)	JPS574954A (es)
KR (1)	KR840001071B1 (es)
AR (1)	AR228596A1 (es)
AT (1)	ATE9897T1 (es)
AU (1)	AU543345B2 (es)
BG (1)	BG35464A3 (es)
CA (1)	CA1172646A (es)
CS (1)	CS225833B2 (es)
DD (1)	DD158395A5 (es)
DE (1)	DE3166679D1 (es)
DK (1)	DK172181A (es)
ES (1)	ES8302632A1 (es)
FI (1)	FI75337C (es)
GB (1)	GB2074161B (es)
GR (1)	GR73824B (es)
IE (1)	IE51221B1 (es)
IL (1)	IL62669A (es)
NZ (1)	NZ196814A (es)
PH (1)	PH15857A (es)
PL (1)	PL131122B1 (es)
PT (1)	PT72854B (es)
RO (1)	RO82739B (es)
SU (1)	SU1297724A3 (es)
ZA (1)	ZA812482B (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4552982A (en) *	1983-08-01	1985-11-12	Eli Lilly And Company	Synthesis of 9-carbamoyl-9-(3-aminopropyl)fluorenes
US4508735A (en) *	1983-09-21	1985-04-02	Eli Lilly And Company	Anti-arrhythmic N-alkanoylaminoalkyl fluorenes
US4585894A (en) *	1983-10-19	1986-04-29	Eli Lilly And Company	Process for producing 9-carbamoyl fluorene derivatives
FI844067L (fi) *	1983-10-19	1985-04-20	Lilly Co Eli	Foerfarande foer framstaellning av 9-karbamoylfluorenderivat.
US4486592A (en) *	1983-10-19	1984-12-04	Eli Lilly And Company	9-Carbamoylfluorene derivatives
US4842420A (en) *	1987-12-14	1989-06-27	Mobil Oil Corporation	Variable-width draw tape for thermoplastic bags
US5736578A (en) *	1995-06-06	1998-04-07	Bristol-Myers Squibb Company	Ethylamido fluorenes and improved method of making same
ATE264833T1 (de) *	1996-01-16	2004-05-15	Bristol Myers Squibb Co	Konformationseingeschränkte aromatische inhibitoren des microsomalen triglyceridtransferproteins und verfahren
US5760246A (en)	1996-12-17	1998-06-02	Biller; Scott A.	Conformationally restricted aromatic inhibitors of microsomal triglyceride transfer protein and method
CN100463249C (zh) *	2006-01-24	2009-02-18	吉林大学	电化学沉积制备有机发光薄膜的方法及在发光器件中的应用
US7520124B2 (en) *	2006-09-12	2009-04-21	United Technologies Corporation	Asymmetric serrated nozzle for exhaust noise reduction

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US2280058A (en) *		1942-04-21		Cyanoethylation of carbocycijc
NL287095A (es)	1962-12-21	1965-02-25
US3325544A (en) *	1965-06-10	1967-06-13	Upjohn Co	9-(2-amino-1-methylethyl) fluoren-9-ol and salts thereof
US3660485A (en) *	1970-10-05	1972-05-02	Searle & Co	Fluorene-9-carboxylic acid hydrazides
US3843657A (en) *	1972-12-08	1974-10-22	Searle & Co	9-dialkylamin oalkyl-n-substituted fluorene-9-carboxamides

1980
- 1980-04-17 US US06/141,229 patent/US4282170A/en not_active Expired - Lifetime
1981
- 1981-04-14 GR GR64688A patent/GR73824B/el unknown
- 1981-04-14 PH PH25498A patent/PH15857A/en unknown
- 1981-04-14 AR AR284966A patent/AR228596A1/es active
- 1981-04-14 PT PT72854A patent/PT72854B/pt not_active IP Right Cessation
- 1981-04-14 NZ NZ196814A patent/NZ196814A/en unknown
- 1981-04-14 CA CA000375408A patent/CA1172646A/en not_active Expired
- 1981-04-14 ZA ZA00812482A patent/ZA812482B/xx unknown
- 1981-04-14 CS CS812820A patent/CS225833B2/cs unknown
- 1981-04-14 ES ES501339A patent/ES8302632A1/es not_active Expired
- 1981-04-15 DE DE8181301666T patent/DE3166679D1/de not_active Expired
- 1981-04-15 GB GB8111886A patent/GB2074161B/en not_active Expired
- 1981-04-15 AT AT81301666T patent/ATE9897T1/de active
- 1981-04-15 FI FI811176A patent/FI75337C/fi not_active IP Right Cessation
- 1981-04-15 DK DK172181A patent/DK172181A/da active IP Right Grant
- 1981-04-15 EP EP81301666A patent/EP0038676B1/en not_active Expired
- 1981-04-16 PL PL1981230714A patent/PL131122B1/pl unknown
- 1981-04-16 IE IE873/81A patent/IE51221B1/en not_active IP Right Cessation
- 1981-04-16 AU AU69611/81A patent/AU543345B2/en not_active Ceased
- 1981-04-16 JP JP5835681A patent/JPS574954A/ja active Granted
- 1981-04-16 RO RO104045A patent/RO82739B/ro unknown
- 1981-04-16 SU SU813310061A patent/SU1297724A3/ru active
- 1981-04-16 DD DD81229304A patent/DD158395A5/de not_active IP Right Cessation
- 1981-04-16 BG BG8151701A patent/BG35464A3/xx unknown
- 1981-04-17 IL IL62669A patent/IL62669A/xx unknown
- 1981-04-17 KR KR1019810001317A patent/KR840001071B1/ko active
1988
- 1988-10-04 JP JP63251711A patent/JPH01125363A/ja active Granted

Also Published As

Publication number	Publication date
EP0038676A1 (en)	1981-10-28
PH15857A (en)	1983-04-13
IE51221B1 (en)	1986-11-12
DE3166679D1 (en)	1984-11-22
ATE9897T1 (de)	1984-11-15
GR73824B (es)	1984-05-03
FI811176L (fi)	1981-10-18
GB2074161A (en)	1981-10-28
JPS574954A (en)	1982-01-11
PT72854B (en)	1982-03-30
FI75337B (fi)	1988-02-29
ES501339A0 (es)	1983-01-16
KR830005110A (ko)	1983-07-23
AU6961181A (en)	1981-10-22
ZA812482B (en)	1982-11-24
IE810873L (en)	1981-10-17
RO82739B (ro)	1984-01-30
NZ196814A (en)	1984-07-06
IL62669A (en)	1984-06-29
CA1172646A (en)	1984-08-14
CS225833B2 (en)	1984-02-13
BG35464A3 (en)	1984-04-15
SU1297724A3 (ru)	1987-03-15
PL230714A1 (es)	1982-08-02
DK172181A (da)	1981-10-18
DD158395A5 (de)	1983-01-12
JPH0149701B2 (es)	1989-10-25
US4282170A (en)	1981-08-04
ES8302632A1 (es)	1983-01-16
KR840001071B1 (ko)	1984-07-31
IL62669A0 (en)	1981-06-29
JPH01125363A (ja)	1989-05-17
FI75337C (fi)	1988-06-09
RO82739A (ro)	1984-01-14
PT72854A (en)	1981-05-01
EP0038676B1 (en)	1984-10-17
JPH0153267B2 (es)	1989-11-13
GB2074161B (en)	1984-03-14
PL131122B1 (en)	1984-10-31
AU543345B2 (en)	1985-04-18

Publication	Publication Date	Title
MX7035E (es)	1987-03-06	Procedimiento para preparar 3-isoxazolidinona
ES493948A0 (es)	1981-06-16	Procedimiento para generar halogenos
AR226212A1 (es)	1982-06-15	Procedimiento para preparar nuevos derivados de imidazo rifamicina
MX5995E (es)	1984-09-18	Procedimiento para preparar 6-n-propil-8-metilmercapto-metilergolinas
ES489376A0 (es)	1980-12-16	Dispositivo para accionar las viseras de cascos o similares
ES493128A0 (es)	1981-04-01	Procedimiento para purificar polisacaridos capsulares neumo-coccicos
MX5926E (es)	1984-08-29	Procedimiento para preparar 4-pirimidonas
AR227453A1 (es)	1982-10-29	Poliesterimida y procedimiento para prepararla
ES496713A0 (es)	1982-05-01	Procedimiento para preparar alfa-aril-in-imidazol-1-etanoles
AR230995A1 (es)	1984-08-31	Procedimiento para producir n-fosfono-metilglicina
AR225048A1 (es)	1982-02-15	Nuevas nikkomicinas de propiedades plaguicidas,y desprovistas de actividad terapeutica,procedimientos para producirlas y composiciones plaguicidas que las contienen
ES521744A0 (es)	1984-01-16	Procedimiento para preparar ciclohexanol y ciclohexanona.
AR228596A1 (es)	1983-03-30	9-(2-cianoetil)-9-carbamoil-fluorenos,exentos de aplicaciones terapeuticas y utiles como intermediarios para preparar 9-carbamoil-9-amino-propil-fluorenos
ES491196A0 (es)	1981-04-01	Procedimiento para preparar nuevas antraceno-9, 10-bis-car- bonilhidrazonas
AR230271A1 (es)	1984-03-01	1-fenil-piridazonas,procedimiento para prepararlas y agentes herbicidas que las contienen
ES505105A0 (es)	1982-08-16	Procedimiento para esterificar alfa-l-aspartil-l-fenilalani-na
ES489694A0 (es)	1981-02-16	Procedimiento mejorado para purificar polisacaridos capsula-res
ES523497A0 (es)	1984-10-01	Procedimiento para preparar n-fosfonometilglicina.
FI801094A (fi)	1980-10-10	Underhaollningsflake som aer bildad pao ingaoende stoedbalkar
ES490121A0 (es)	1981-04-01	Procedimiento para preparar piranonas 6-sustituidas
AR225318A1 (es)	1982-03-15	Procedimiento para preparar fenil-propil-morfolinas sustituidas
AR226546A1 (es)	1982-07-30	Procedimiento para purificar(n-pirazolil-1-metil)-haloacetanilidas
MX162875B (es)	1991-07-02	Procedimiento para formar perlas de azufre
ES503266A0 (es)	1982-04-01	Procedimiento de preparar 6-hidrazonopirido(2,1-b)quinazo- lin-11-onas y similares
ES518959A0 (es)	1984-03-01	Procedimiento para preparar fenilureas.