AR110919A1 - Membrana de fibras huecas con biocompatibilidad mejorada y elución reducida de polímeros hidrofílicos - Google Patents

Membrana de fibras huecas con biocompatibilidad mejorada y elución reducida de polímeros hidrofílicos

Info

Publication number
AR110919A1
AR110919A1 ARP180100226A ARP180100226A AR110919A1 AR 110919 A1 AR110919 A1 AR 110919A1 AR P180100226 A ARP180100226 A AR P180100226A AR P180100226 A ARP180100226 A AR P180100226A AR 110919 A1 AR110919 A1 AR 110919A1
Authority
AR
Argentina
Prior art keywords
membrane
polymers
hollow fibers
hydrophyl
improved biocompatibility
Prior art date
Application number
ARP180100226A
Other languages
English (en)
Inventor
Dietmar Hansel
Rainer Fislage
Michael Paul
Original Assignee
Fresenius Medical Care Deutschland Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fresenius Medical Care Deutschland Gmbh filed Critical Fresenius Medical Care Deutschland Gmbh
Publication of AR110919A1 publication Critical patent/AR110919A1/es

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D69/00—Semi-permeable membranes for separation processes or apparatus characterised by their form, structure or properties; Manufacturing processes specially adapted therefor
    • B01D69/08—Hollow fibre membranes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
    • A61M1/1621—Constructional aspects thereof
    • A61M1/1623—Disposition or location of membranes relative to fluids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
    • B01D61/24—Dialysis ; Membrane extraction
    • B01D61/243—Dialysis
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D67/00—Processes specially adapted for manufacturing semi-permeable membranes for separation processes or apparatus
    • B01D67/0002—Organic membrane manufacture
    • B01D67/0009—Organic membrane manufacture by phase separation, sol-gel transition, evaporation or solvent quenching
    • B01D67/0011—Casting solutions therefor
    • B01D67/00111—Polymer pretreatment in the casting solutions
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D67/00—Processes specially adapted for manufacturing semi-permeable membranes for separation processes or apparatus
    • B01D67/0002—Organic membrane manufacture
    • B01D67/0009—Organic membrane manufacture by phase separation, sol-gel transition, evaporation or solvent quenching
    • B01D67/0016—Coagulation
    • B01D67/00165—Composition of the coagulation baths
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D69/00—Semi-permeable membranes for separation processes or apparatus characterised by their form, structure or properties; Manufacturing processes specially adapted therefor
    • B01D69/02—Semi-permeable membranes for separation processes or apparatus characterised by their form, structure or properties; Manufacturing processes specially adapted therefor characterised by their properties
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D69/00—Semi-permeable membranes for separation processes or apparatus characterised by their form, structure or properties; Manufacturing processes specially adapted therefor
    • B01D69/08—Hollow fibre membranes
    • B01D69/087—Details relating to the spinning process
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D69/00—Semi-permeable membranes for separation processes or apparatus characterised by their form, structure or properties; Manufacturing processes specially adapted therefor
    • B01D69/14—Dynamic membranes
    • B01D69/141—Heterogeneous membranes, e.g. containing dispersed material; Mixed matrix membranes
    • B01D69/142—Heterogeneous membranes, e.g. containing dispersed material; Mixed matrix membranes with "carriers"
    • B01D69/144—Heterogeneous membranes, e.g. containing dispersed material; Mixed matrix membranes with "carriers" containing embedded or bound biomolecules
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D71/00—Semi-permeable membranes for separation processes or apparatus characterised by the material; Manufacturing processes specially adapted therefor
    • B01D71/06—Organic material
    • B01D71/44—Polymers obtained by reactions only involving carbon-to-carbon unsaturated bonds, not provided for in a single one of groups B01D71/26-B01D71/42
    • B01D71/441—Polyvinylpyrrolidone
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D71/00—Semi-permeable membranes for separation processes or apparatus characterised by the material; Manufacturing processes specially adapted therefor
    • B01D71/06—Organic material
    • B01D71/66—Polymers having sulfur in the main chain, with or without nitrogen, oxygen or carbon only
    • B01D71/68—Polysulfones; Polyethersulfones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/75—General characteristics of the apparatus with filters
    • A61M2205/7527—General characteristics of the apparatus with filters liquophilic, hydrophilic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/75—General characteristics of the apparatus with filters
    • A61M2205/7536—General characteristics of the apparatus with filters allowing gas passage, but preventing liquid passage, e.g. liquophobic, hydrophobic, water-repellent membranes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2207/00—Methods of manufacture, assembly or production
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2323/00—Details relating to membrane preparation
    • B01D2323/15—Use of additives
    • B01D2323/218—Additive materials
    • B01D2323/2182—Organic additives
    • B01D2323/21839—Polymeric additives
    • B01D2323/2187—Polyvinylpyrolidone
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2325/00—Details relating to properties of membranes
    • B01D2325/36—Hydrophilic membranes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2325/00—Details relating to properties of membranes
    • B01D2325/38—Hydrophobic membranes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Dispersion Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Manufacturing & Machinery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Water Supply & Treatment (AREA)
  • Hematology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Vascular Medicine (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Emergency Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • External Artificial Organs (AREA)
  • Artificial Filaments (AREA)
  • Compositions Of Macromolecular Compounds (AREA)

Abstract

Preparación de membranas de fibras huecas a base de un polímero hidrofóbico y un polímero hidrofílico, que contienen un antioxidante no hidrosoluble, en especial la presente se refiere a la preparación de membranas de fibras huecas para el tratamiento extracorpóreo de la sangre, en donde las membranas de fibras huecas presentan biocompatibilidad mejorada respecto a la sangre de tratamiento, en especial provocan una menor activación del complemento y una menor pérdida de trombocitos respecto de la sangre de tratamiento. Al mismo tiempo, se reduce la elución de polímeros hidrofílicos del lumen de la membrana de fibras huecas.
ARP180100226A 2017-02-01 2018-01-31 Membrana de fibras huecas con biocompatibilidad mejorada y elución reducida de polímeros hidrofílicos AR110919A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE102017201630.2A DE102017201630A1 (de) 2017-02-01 2017-02-01 Hohlfasermembran mit verbesserter Biokompatibilität

Publications (1)

Publication Number Publication Date
AR110919A1 true AR110919A1 (es) 2019-05-15

Family

ID=61244551

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP180100226A AR110919A1 (es) 2017-02-01 2018-01-31 Membrana de fibras huecas con biocompatibilidad mejorada y elución reducida de polímeros hidrofílicos

Country Status (13)

Country Link
US (2) US11484844B2 (es)
EP (2) EP4368282A2 (es)
JP (2) JP7200133B2 (es)
KR (1) KR102499302B1 (es)
CN (1) CN110234421A (es)
AR (1) AR110919A1 (es)
AU (1) AU2018215971B2 (es)
BR (2) BR112019015665A2 (es)
CA (1) CA3052222A1 (es)
DE (1) DE102017201630A1 (es)
EA (1) EA038775B1 (es)
TW (1) TWI805566B (es)
WO (1) WO2018141780A1 (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102017201630A1 (de) 2017-02-01 2018-08-02 Fresenius Medical Care Deutschland Gmbh Hohlfasermembran mit verbesserter Biokompatibilität
DE102018100568A1 (de) * 2018-01-11 2019-07-11 B. Braun Avitum Ag Blutbehandlungsmaschine mit einem Hohlfaserfiltermodul zur horizontalen Anordnung sowie ein Hohlfaserfiltermodul und dessen Verwendung
US11149969B2 (en) * 2018-02-23 2021-10-19 Andersen Corporation Controlled low humidity storage device and methods
US20210316045A1 (en) * 2018-10-25 2021-10-14 Hollister Incorporated Hydrophilic coatings for medical devices
DE102020206867A1 (de) 2020-06-02 2021-12-02 Fresenius Medical Care Deutschland Gmbh Hohlfasermembran für die abtrennung von blutplasma aus blut
EP4232184A1 (en) 2020-10-30 2023-08-30 Fresenius Medical Care Holdings, Inc. Hemodialyzer
CN112505081A (zh) * 2020-11-18 2021-03-16 中国科学院生态环境研究中心 一种中空纤维膜ToF-SIMS测试的制样方法
DE102021112314A1 (de) 2021-05-11 2022-11-17 Fresenius Medical Care Deutschland Gmbh Hohlfasermembranfilter mit verbesserten Trenneigenschaften

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DE102017201630A1 (de) 2017-02-01 2018-08-02 Fresenius Medical Care Deutschland Gmbh Hohlfasermembran mit verbesserter Biokompatibilität

Also Published As

Publication number Publication date
CA3052222A1 (en) 2018-08-09
US11484844B2 (en) 2022-11-01
EP4368282A2 (de) 2024-05-15
EA201991814A1 (ru) 2019-12-30
BR122024002579A2 (pt) 2024-03-12
TW201835394A (zh) 2018-10-01
AU2018215971B2 (en) 2023-04-13
DE102017201630A1 (de) 2018-08-02
JP7506127B2 (ja) 2024-06-25
US20200188860A1 (en) 2020-06-18
JP2020508869A (ja) 2020-03-26
BR112019015665A2 (pt) 2020-03-31
EP3576866B1 (de) 2024-05-01
US20230054223A1 (en) 2023-02-23
JP2022189872A (ja) 2022-12-22
EP3576866A1 (de) 2019-12-11
TWI805566B (zh) 2023-06-21
KR20190107685A (ko) 2019-09-20
JP7200133B2 (ja) 2023-01-06
WO2018141780A1 (de) 2018-08-09
CN110234421A (zh) 2019-09-13
AU2018215971A1 (en) 2019-09-19
KR102499302B1 (ko) 2023-02-10
US11872530B2 (en) 2024-01-16
EA038775B1 (ru) 2021-10-18

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