AR104691A1 - Composición veterinaria de imidacloprid, moxidectina y praziquantel de administración tópica cutánea (spot on) para tratamiento y prevención de las ecto y endoparasitosis que afectan a los perros - Google Patents

Composición veterinaria de imidacloprid, moxidectina y praziquantel de administración tópica cutánea (spot on) para tratamiento y prevención de las ecto y endoparasitosis que afectan a los perros

Info

Publication number
AR104691A1
AR104691A1 ARP160101448A ARP160101448A AR104691A1 AR 104691 A1 AR104691 A1 AR 104691A1 AR P160101448 A ARP160101448 A AR P160101448A AR P160101448 A ARP160101448 A AR P160101448A AR 104691 A1 AR104691 A1 AR 104691A1
Authority
AR
Argentina
Prior art keywords
praziquantel
imidacloprid
spot
veterinary composition
endoparasitosis
Prior art date
Application number
ARP160101448A
Other languages
English (en)
Original Assignee
Labyes De Uruguay S A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Labyes De Uruguay S A filed Critical Labyes De Uruguay S A
Priority to ARP160101448A priority Critical patent/AR104691A1/es
Priority to PCT/US2017/032851 priority patent/WO2017201010A1/en
Priority to CN202211444401.7A priority patent/CN115737649A/zh
Priority to MX2018013630A priority patent/MX2018013630A/es
Priority to CN201780018784.2A priority patent/CN108883092A/zh
Priority to CN202211444380.9A priority patent/CN115645412A/zh
Priority to US16/074,696 priority patent/US10695331B2/en
Priority to ES17799990T priority patent/ES2954856T3/es
Priority to JP2019512939A priority patent/JP2019516793A/ja
Priority to EP17799990.1A priority patent/EP3458051B1/en
Priority to BR112018073613-9A priority patent/BR112018073613A2/pt
Publication of AR104691A1 publication Critical patent/AR104691A1/es
Priority to JP2021206614A priority patent/JP7255043B2/ja

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A61K9/0017—Non-human animal skin, e.g. pour-on, spot-on
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/14—Ectoparasiticides, e.g. scabicides

Abstract

Una composición veterinaria monodosis de aplicación tópica (spot-on) para canes que comprende: (a) Imidacloprid, entre 8,18 y 10,00%; (b) Moxidectina, entre 2,86 y 3,50%; (c) Praziquantel, entre 8,18 y 10,00%; y (d) un solvente aprótico seleccionado de Dimetil sulfóxido (DMSO), N,N-dimetilacetamida (DMAC), N,N-dimetilformamida (DMF), y sus mezclas, entre 65,45 y 80,00%; junto con excipientes veterinariamente aceptables, y en donde los % están referidos al peso total de la composición. Uso de una cantidad efectiva de: (a) Imidacloprid; (b) Moxidectina; (c) Praziquantel; y (d) un solvente aprótico seleccionado de Dimetil sulfóxido (DMSO), N,N-dimetilacetamida (DMAC), N,N-dimetilformamida (DMF) y sus mezclas, junto con excipientes veterinariamente aceptables, para la preparación de una composición veterinaria monodosis para el tratamiento, control y prevención de las ecto y endoparasitosis de canes, en donde dicha composición veterinaria está adaptada para ser administrada tópicamente (spot-on).
ARP160101448A 2016-05-18 2016-05-18 Composición veterinaria de imidacloprid, moxidectina y praziquantel de administración tópica cutánea (spot on) para tratamiento y prevención de las ecto y endoparasitosis que afectan a los perros AR104691A1 (es)

Priority Applications (12)

Application Number Priority Date Filing Date Title
ARP160101448A AR104691A1 (es) 2016-05-18 2016-05-18 Composición veterinaria de imidacloprid, moxidectina y praziquantel de administración tópica cutánea (spot on) para tratamiento y prevención de las ecto y endoparasitosis que afectan a los perros
CN202211444380.9A CN115645412A (zh) 2016-05-18 2017-05-16 治疗和预防犬的外寄生虫病和内寄生虫病的兽药组合物
CN202211444401.7A CN115737649A (zh) 2016-05-18 2017-05-16 治疗和预防犬的外寄生虫病和内寄生虫病的兽药组合物
MX2018013630A MX2018013630A (es) 2016-05-18 2017-05-16 Composicion veterinaria de imidacloprid, moxidectina y praziquantel de administracion topica cutanea (spot on) para tratamiento y prevencion de las ecto y endoparasitosis que afectan a los perros.
CN201780018784.2A CN108883092A (zh) 2016-05-18 2017-05-16 用于治疗和预防影响犬的外寄生虫病和内寄生虫病的用于皮肤表面施用(喷滴)的包含吡虫啉、莫昔克丁和吡喹酮的兽药组合物
PCT/US2017/032851 WO2017201010A1 (en) 2016-05-18 2017-05-16 Veterinary composition comprising imidacloprid, moxidectin and praziquantel for cutaneous topical application (spot on), for the treatment and prevention of ecto and endoparasitoses affecting dogs
US16/074,696 US10695331B2 (en) 2016-05-18 2017-05-16 Veterinary composition comprising imidacloprid, moxidectin and praziquantel for cutaneous topical application (spot on), for the treatment and prevention of ecto and endoparasitoses affecting dogs
ES17799990T ES2954856T3 (es) 2016-05-18 2017-05-16 Composición veterinaria de imidacloprid, moxidectina y praziquantel de administración tópica cutánea (spot on) para tratamiento y prevención de las ecto y endoparasitosis que afectan a los perros
JP2019512939A JP2019516793A (ja) 2016-05-18 2017-05-16 イミダクロプリド、モキシデクチン及びプラジカンテルを含む、イヌを冒す外部及び内部の寄生虫病の治療及び予防用の皮膚局所適用（スポットオン）するための獣医学的組成物
EP17799990.1A EP3458051B1 (en) 2016-05-18 2017-05-16 Veterinary composition comprising imidacloprid, moxidectin and praziquantel for cutaneous topical application (spot on), for the treatment and prevention of ecto and endoparasitoses affecting dogs
BR112018073613-9A BR112018073613A2 (pt) 2016-05-18 2017-05-16 composição veterinária monodose para aplicação tópica (spot on) para caninos e uso de uma quantidade eficaz de imidacloprido, moxidectina, praziquantel e um solvente aprótico
JP2021206614A JP7255043B2 (ja) 2016-05-18 2021-12-21 イミダクロプリド、モキシデクチン及びプラジカンテルを含む、イヌ（犬）を冒す外部及び内部の寄生虫病の治療及び予防用の皮膚局所適用（スポットオン）するための獣医学的組成物

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ARP160101448A AR104691A1 (es) 2016-05-18 2016-05-18 Composición veterinaria de imidacloprid, moxidectina y praziquantel de administración tópica cutánea (spot on) para tratamiento y prevención de las ecto y endoparasitosis que afectan a los perros

Publications (1)

Publication Number Publication Date
AR104691A1 true AR104691A1 (es) 2017-08-09

Family

ID=59714807

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP160101448A AR104691A1 (es) 2016-05-18 2016-05-18 Composición veterinaria de imidacloprid, moxidectina y praziquantel de administración tópica cutánea (spot on) para tratamiento y prevención de las ecto y endoparasitosis que afectan a los perros

Country Status (9)

Country Link
US (1) US10695331B2 (es)
EP (1) EP3458051B1 (es)
JP (2) JP2019516793A (es)
CN (3) CN115645412A (es)
AR (1) AR104691A1 (es)
BR (1) BR112018073613A2 (es)
ES (1) ES2954856T3 (es)
MX (1) MX2018013630A (es)
WO (1) WO2017201010A1 (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114698369A (zh) * 2019-08-14 2022-07-01 威隆股份公司 用于防治寄生虫的包含替戈拉纳的组合物
CN110772509A (zh) * 2019-10-17 2020-02-11 广东省农业科学院动物卫生研究所 一种吡虫啉与莫昔克丁二元醇质体及其制备方法和应用
SI3815677T1 (sl) 2019-10-30 2023-12-29 Krka, D.D., Novo Mesto Stabilni veterinarski sestavek, ki obsega moksidektin in imidakloprid
CN114259464B (zh) * 2021-11-25 2022-11-22 吉林大学 一种复方莫昔克丁外用滴剂

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US4447414A (en) * 1982-12-21 1984-05-08 Cutter Laboratories, Inc. Carnivore anthelmintics
JPS6058914A (ja) * 1983-09-12 1985-04-05 Shionogi & Co Ltd イミダゾ−ル系抗真菌性外用ゲル製剤
JP2006522154A (ja) * 2003-04-04 2006-09-28 メリアル リミテッド 動物用駆虫局所製剤
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WO2011075592A1 (en) * 2009-12-17 2011-06-23 Merial Limited Compositions comprising macrocyclic lactone compounds and spirodioxepinoindoles
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Also Published As

Publication number Publication date
EP3458051B1 (en) 2023-06-07
JP2019516793A (ja) 2019-06-20
CN115737649A (zh) 2023-03-07
US20190070158A1 (en) 2019-03-07
EP3458051A1 (en) 2019-03-27
WO2017201010A1 (en) 2017-11-23
JP2022052770A (ja) 2022-04-04
MX2018013630A (es) 2019-06-17
CN108883092A (zh) 2018-11-23
BR112018073613A2 (pt) 2019-02-26
EP3458051C0 (en) 2023-06-07
EP3458051A4 (en) 2020-01-08
CN115645412A (zh) 2023-01-31
JP7255043B2 (ja) 2023-04-11
ES2954856T3 (es) 2023-11-27
US10695331B2 (en) 2020-06-30

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