AR100846A1 - FORMULACIONES INTRAVAGINALES QUE COMPRENDEN GnRH - Google Patents

FORMULACIONES INTRAVAGINALES QUE COMPRENDEN GnRH

Info

Publication number
AR100846A1
AR100846A1 ARP150101903A ARP150101903A AR100846A1 AR 100846 A1 AR100846 A1 AR 100846A1 AR P150101903 A ARP150101903 A AR P150101903A AR P150101903 A ARP150101903 A AR P150101903A AR 100846 A1 AR100846 A1 AR 100846A1
Authority
AR
Argentina
Prior art keywords
acid
formulation
intravaginal
gnrh
amount
Prior art date
Application number
ARP150101903A
Other languages
English (en)
Inventor
P Kolbasa Karen
A Wicks Nicholas
C Sucheta Susan
Luo Laibin
L Feenstra Kenneth
Original Assignee
Zoetis Services Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zoetis Services Llc filed Critical Zoetis Services Llc
Publication of AR100846A1 publication Critical patent/AR100846A1/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08Peptides having 5 to 11 amino acids
    • A61K38/09Luteinising hormone-releasing hormone [LHRH], i.e. Gonadotropin-releasing hormone [GnRH]; Related peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12Carboxylic acids; Salts or anhydrides thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0034Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/02Suppositories; Bougies; Bases therefor; Ovules
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/02Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Reproductive Health (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Endocrinology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gynecology & Obstetrics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Urology & Nephrology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • Pregnancy & Childbirth (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Formulación intravaginal, que comprende un ácido carboxílico en una cantidad del 10 - 20% peso/peso de dicha formulación, una base oleaginosa, que tiene una temperatura de fusión entre 30ºC y 38ºC, GnRH o uno de sus análogos, en una cantidad equivalente a la cantidad de GnRH de entre 10 mg y 600 mg. También se proporciona un método para inducir ovulación en un rumiante usando la formulación. Reivindicación 15: La formulación intravaginal de una cualquiera de las reivindicaciones 1 - 14, caracterizada porque el ácido carboxílico está seleccionado entre el grupo que consiste en ácido cítrico, ácido succínico, ácido tartárico, ácido glicólico, ácido ascórbico, ácido láctico, ácido aspártico, edetato de dipotasio o una de sus combinaciones. Reivindicación 16: La formulación intravaginal de la reivindicación 15, caracterizada porque dicho ácido carboxílico es ácido cítrico.
ARP150101903A 2014-06-16 2015-06-15 FORMULACIONES INTRAVAGINALES QUE COMPRENDEN GnRH AR100846A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201462012523P 2014-06-16 2014-06-16

Publications (1)

Publication Number Publication Date
AR100846A1 true AR100846A1 (es) 2016-11-02

Family

ID=53773489

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP150101903A AR100846A1 (es) 2014-06-16 2015-06-15 FORMULACIONES INTRAVAGINALES QUE COMPRENDEN GnRH

Country Status (14)

Country Link
US (1) US20170143786A1 (es)
EP (1) EP3154519A1 (es)
JP (1) JP2017519769A (es)
CN (1) CN106456705A (es)
AR (1) AR100846A1 (es)
AU (1) AU2015277613A1 (es)
BR (1) BR112016028875A2 (es)
CA (1) CA2951532A1 (es)
CL (1) CL2016003220A1 (es)
IL (1) IL249121A0 (es)
MX (1) MX2016016768A (es)
RU (1) RU2016146994A (es)
UY (1) UY36168A (es)
WO (1) WO2015195333A1 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11376220B2 (en) 2017-06-30 2022-07-05 Therio, LLC Single-injection methods and formulations to induce and control multiple ovarian follicles in bovine, caprine, ovine, camelid and other female animals

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4211769A (en) * 1977-08-24 1980-07-08 Takeda Chemical Industries, Ltd. Preparations for vaginal administration
AU2063197A (en) * 1996-03-04 1997-09-22 Massachusetts Institute Of Technology Materials and methods for enhancing cellular internalization
CN101692985A (zh) * 2009-09-29 2010-04-14 浙江大学 一种诱导奶牛定时***进行人工授精的方法
CN101779988A (zh) * 2010-02-03 2010-07-21 李树静 一种青年牛高强度重复超数***的方法

Also Published As

Publication number Publication date
BR112016028875A2 (pt) 2017-08-22
MX2016016768A (es) 2017-04-04
CA2951532A1 (en) 2015-12-23
US20170143786A1 (en) 2017-05-25
CL2016003220A1 (es) 2017-06-02
RU2016146994A (ru) 2018-07-16
JP2017519769A (ja) 2017-07-20
RU2016146994A3 (es) 2018-07-16
IL249121A0 (en) 2017-01-31
AU2015277613A1 (en) 2016-12-08
UY36168A (es) 2016-01-29
CN106456705A (zh) 2017-02-22
EP3154519A1 (en) 2017-04-19
WO2015195333A1 (en) 2015-12-23

Similar Documents

Publication Publication Date Title
PH12019550050A1 (en) Isoxazole analogs as fxr agonists and methods of use thereof
NI201800023A (es) Compuestos antivirales de fosfodiamida de éster de beta-aminoácido
CO2019003630A2 (es) Composiciones no proteínicas de toxina clostridial
CL2018001478A1 (es) Agonistas del receptor de apelina y métodos de uso
CL2020000926A1 (es) Composiciones para la liberación controlada de ingredientes activos y método para hacer las mismas. (divisional solicitud 201802371)
MY196909A (en) Boronic acid derivatives and therapeutic uses thereof
EA201891438A1 (ru) Кислотно-аддитивные соли производных пиперазина
CL2015002628A1 (es) Compuestos de heteroarilo y sus usos.
UY36215A (es) Espirocicloheptanos como inhibidores de rock
CL2018001621A1 (es) Heteroarilhidroxipirimidinonas como agonistas del receptor de apelina (apj)
UY37073A (es) Salicilamidas espiroheptanos y compuestos relacionados como inhibidores de rock, y las composiciones que los contienen
EA201692301A1 (ru) Производные бороновой кислоты и их терапевтическое применение
EA201691988A1 (ru) Производные бороновой кислоты и их терапевтическое применение
CL2017000071A1 (es) Acidos carboxílicos hterocíclicos como activadores de guanilato ciclasa soluble.
EA201691512A1 (ru) Бензохинолиновые ингибиторы везикулярного переносчика моноамина 2
UY36118A (es) Compuestos y composiciones para inducir condrogénesis
CL2016001918A1 (es) Heteroaril amidas como inhibidores de agregación de proteína
EA201691808A1 (ru) Кортикостероидные композиции для местного применения
EA201790787A1 (ru) Снижение вязкости фармацевтических составов
CO2019011546A2 (es) Compuestos y métodos para el tratamiento de enfermedades parasitarias
BR112017004393A2 (pt) formulações de anticorpo
PE20181040A1 (es) Formulacion solida oral que contiene irinotecan y metodo de preparacion de la misma
AR101414A1 (es) Derivados de pirrolidinona como inhibidores de metap-2
EA201990998A1 (ru) Фармацевтические составы и способы их получения
CL2019001746A1 (es) Amidas aromáticas de ácido carboxílico

Legal Events

Date Code Title Description
FB Suspension of granting procedure