AR096135A1 - Derivados de la quinolona - Google Patents
Derivados de la quinolonaInfo
- Publication number
- AR096135A1 AR096135A1 ARP140101763A ARP140101763A AR096135A1 AR 096135 A1 AR096135 A1 AR 096135A1 AR P140101763 A ARP140101763 A AR P140101763A AR P140101763 A ARP140101763 A AR P140101763A AR 096135 A1 AR096135 A1 AR 096135A1
- Authority
- AR
- Argentina
- Prior art keywords
- diyl
- nitrogen atoms
- group
- quinolona
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Communicable Diseases (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Oncology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Dermatology (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Epidemiology (AREA)
Abstract
Composiciones farmacéuticas que las contienen y a los usos de estos compuestos en la elaboración de medicamentos para el tratamiento de infecciones bacterianas. Reivindicación 1: Un compuesto de la fórmula (1), donde R¹ representa alquilo C₁₋₃ o cicloalquilo C₃₋₅; U representa CH o N; V representa O ó S; y A representa un grupo de unión que consta de un grupo de cadena recta saturado de 1, 2 ó 3 miembros que se une a -o está interrumpido por- un grupo cíclico de 6 miembros que se selecciona de ciclohexan-1,4-diilo, piperidin-1,4-diilo y piperazin-1,4-diilo; donde dicho grupo de unión contiene un total de entre dos y tres átomos de nitrógeno, donde dichos átomos de nitrógeno se separan entre sí por al menos dos átomos de carbono; o una de sus sales farmacéuticamente aceptables.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IB2013053472 | 2013-05-02 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR096135A1 true AR096135A1 (es) | 2015-12-09 |
Family
ID=50819763
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP140101763A AR096135A1 (es) | 2013-05-02 | 2014-04-29 | Derivados de la quinolona |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US9540399B2 (es) |
| EP (1) | EP2991992B1 (es) |
| JP (1) | JP6337095B2 (es) |
| KR (1) | KR20160003244A (es) |
| CN (1) | CN105189520B (es) |
| AR (1) | AR096135A1 (es) |
| AU (1) | AU2014261101A1 (es) |
| CA (1) | CA2910042A1 (es) |
| ES (1) | ES2692652T3 (es) |
| MX (1) | MX2015015251A (es) |
| RU (1) | RU2015151456A (es) |
| TW (1) | TW201522348A (es) |
| WO (1) | WO2014178008A1 (es) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2016298826A1 (en) * | 2015-07-28 | 2018-02-15 | Vyome Therapeutics Limited | Antibacterial therapeutics and prophylactics |
| TW201833120A (zh) | 2017-02-17 | 2018-09-16 | 瑞士商愛杜西亞製藥有限公司 | 芳基噁唑啶酮抗生素化合物 |
| TW202116782A (zh) | 2019-07-16 | 2021-05-01 | 瑞士商愛杜西亞製藥有限公司 | 喹啉酮衍生物 |
Family Cites Families (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5649382A (en) | 1979-09-28 | 1981-05-02 | Dainippon Pharmaceut Co Ltd | 6-fluoro-7-cyclic amino-1,8-naphthylidine derivative and its salt |
| DE3508816A1 (de) | 1985-01-10 | 1986-07-10 | Bayer Ag, 5090 Leverkusen | 6,7-disubstituierte 1-cyclopropyl-1,4-dihydro-4-oxo-1,8-naphtyridin-3-carbonsaeuren |
| NZ290722A (en) | 1994-08-02 | 1999-03-29 | Procter & Gamble | A process for making derivatives of quinolonyl lactam (qla's); intermediates |
| JPH09323932A (ja) * | 1996-01-31 | 1997-12-16 | Sankyo Co Ltd | エイズ治療剤又は予防剤 |
| GB0101577D0 (en) * | 2001-01-22 | 2001-03-07 | Smithkline Beecham Plc | Compounds |
| CA2450122C (en) | 2001-06-15 | 2009-10-20 | Microbiotix, Inc. | Novel heterocyclic antibacterial compounds |
| US6777420B2 (en) | 2001-06-15 | 2004-08-17 | Microbiotix, Inc. | Heterocyclic antibacterial compounds |
| TW200507841A (en) | 2003-03-27 | 2005-03-01 | Glaxo Group Ltd | Antibacterial agents |
| AU2005279050A1 (en) * | 2004-07-30 | 2006-03-09 | Centre National De La Recherche Scientifique (Cnrs) | Hybrid molecules QA where Q is an aminoquinoline and A is an antibiotic residue, and the synthesis and uses thereof as antibacterial agents |
| US7511035B2 (en) | 2005-01-25 | 2009-03-31 | Glaxo Group Limited | Antibacterial agents |
| WO2007125952A1 (ja) | 2006-04-28 | 2007-11-08 | Shionogi & Co., Ltd. | Ｎｐｙ ｙ５受容体拮抗作用を有するアミン誘導体 |
| WO2008006648A1 (en) | 2006-06-09 | 2008-01-17 | Glaxo Group Limited | Substituted 1-methyl-1h-quinolin-2-ones and 1-methyl-1h-1,5-naphthyridin-2-ones as antibacterials |
| WO2008143343A1 (ja) | 2007-05-24 | 2008-11-27 | Kyorin Pharmaceutical Co., Ltd. | １４位置換基に複素芳香環カルボン酸構造を有するムチリン誘導体 |
| US7884099B2 (en) | 2007-11-16 | 2011-02-08 | Cumbre Ip Ventures, L.P. | Quinolone carboxylic acid-substituted rifamycin derivatives |
| WO2010019208A1 (en) | 2008-08-11 | 2010-02-18 | Biorelix Pharmaceuticals, Inc. | Flavin derivatives |
| GB0815962D0 (en) | 2008-09-02 | 2008-10-08 | Merlion Pharmaceuticals Pte Ltd | Hybrid antibacterial compounds and their use |
| WO2010045987A1 (en) | 2008-10-23 | 2010-04-29 | Glaxo Group Limited | Substituted (aza) -1-methyl-1h-quin0lin-2-0nes as antibacterials |
| TW201022279A (en) * | 2008-11-14 | 2010-06-16 | Astrazeneca Ab | Chemical compounds |
| JP5662346B2 (ja) * | 2009-01-21 | 2015-01-28 | バジリア ファルマスーチカ アーゲーＢａｓｉｌｅａ Ｐｈａｒｍａｃｅｕｔｉｃａ ＡＧ | 新規二環式抗生物質 |
| WO2011034971A1 (en) | 2009-09-15 | 2011-03-24 | Designmedix, Inc. | Modified fluoroquinolone compounds and methods of using the same |
| TW201121965A (en) | 2009-09-28 | 2011-07-01 | Lg Life Sciences Ltd | Use of a quinolone derivative containing 7-(4-aminomethyl-3-oxime)pyrrolidine group that is capable of inducing granulocyte colony stimulating factor for treatment of neutropenia and recovery of hematopoiesis |
| WO2011094260A2 (en) | 2010-01-26 | 2011-08-04 | Stc. Unm | Novel bifunctional metnase/intnase inhibitors and related compositions and methods of treatment of cancer |
| EP2668177B1 (en) | 2011-01-28 | 2014-10-22 | Boehringer Ingelheim International GmbH | Substituted pyridinyl-pyrimidines and their use as medicaments |
| TW201718506A (zh) | 2011-08-31 | 2017-06-01 | 大塚製藥股份有限公司 | 喹啉酮化合物 |
| KR20140096337A (ko) | 2011-11-08 | 2014-08-05 | 액테리온 파마슈티칼 리미티드 | ２-옥소-옥사졸리딘-３,５-디일 항생제 유도체 |
| US20150126519A1 (en) | 2012-03-20 | 2015-05-07 | Fred Hutchinson Cancer Research Center | Antibiotic compounds and compositions, and methods for identification thereof |
-
2014
- 2014-04-29 AR ARP140101763A patent/AR096135A1/es unknown
- 2014-04-30 CN CN201480024178.8A patent/CN105189520B/zh not_active Expired - Fee Related
- 2014-04-30 AU AU2014261101A patent/AU2014261101A1/en not_active Abandoned
- 2014-04-30 RU RU2015151456A patent/RU2015151456A/ru unknown
- 2014-04-30 CA CA2910042A patent/CA2910042A1/en not_active Abandoned
- 2014-04-30 MX MX2015015251A patent/MX2015015251A/es unknown
- 2014-04-30 JP JP2016511157A patent/JP6337095B2/ja not_active Expired - Fee Related
- 2014-04-30 KR KR1020157034265A patent/KR20160003244A/ko not_active Application Discontinuation
- 2014-04-30 ES ES14726420.4T patent/ES2692652T3/es active Active
- 2014-04-30 TW TW103115665A patent/TW201522348A/zh unknown
- 2014-04-30 US US14/888,581 patent/US9540399B2/en active Active
- 2014-04-30 EP EP14726420.4A patent/EP2991992B1/en not_active Not-in-force
- 2014-04-30 WO PCT/IB2014/061099 patent/WO2014178008A1/en active Application Filing
Also Published As
| Publication number | Publication date |
|---|---|
| KR20160003244A (ko) | 2016-01-08 |
| ES2692652T3 (es) | 2018-12-04 |
| EP2991992A1 (en) | 2016-03-09 |
| AU2014261101A1 (en) | 2015-12-17 |
| CA2910042A1 (en) | 2014-11-06 |
| CN105189520B (zh) | 2017-10-10 |
| TW201522348A (zh) | 2015-06-16 |
| EP2991992B1 (en) | 2018-07-25 |
| JP6337095B2 (ja) | 2018-06-06 |
| WO2014178008A1 (en) | 2014-11-06 |
| US20160060276A1 (en) | 2016-03-03 |
| MX2015015251A (es) | 2016-02-09 |
| RU2015151456A (ru) | 2017-06-07 |
| US9540399B2 (en) | 2017-01-10 |
| JP2016517880A (ja) | 2016-06-20 |
| CN105189520A (zh) | 2015-12-23 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FB | Suspension of granting procedure |