AR079835A1 - CHLORHYDRATE SALT OF 1- (9 - ((3-FLUORO-4-HIDROXI-BENZOIL) -METIL-AMINO) -NONIL) -PIPERIDIN-4-IL ESTER OF ACID BIFENIL-2-IL-CARBAMICO - Google Patents

CHLORHYDRATE SALT OF 1- (9 - ((3-FLUORO-4-HIDROXI-BENZOIL) -METIL-AMINO) -NONIL) -PIPERIDIN-4-IL ESTER OF ACID BIFENIL-2-IL-CARBAMICO

Info

Publication number
AR079835A1
AR079835A1 ARP110100020A ARP110100020A AR079835A1 AR 079835 A1 AR079835 A1 AR 079835A1 AR P110100020 A ARP110100020 A AR P110100020A AR P110100020 A ARP110100020 A AR P110100020A AR 079835 A1 AR079835 A1 AR 079835A1
Authority
AR
Argentina
Prior art keywords
piperidin
fluoro
ester
amino
carbamico
Prior art date
Application number
ARP110100020A
Other languages
Spanish (es)
Original Assignee
Pfizer Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Ltd filed Critical Pfizer Ltd
Publication of AR079835A1 publication Critical patent/AR079835A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40—Oxygen atoms
    • C07D211/44—Oxygen atoms attached in position 4
    • C07D211/46—Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

La presente se refiere a la sal clorhidrato del 1-{9-[(3-fluoro-4-hidroxi-benzoil)-metil-amino]-nonil}-piperidin-4-il éster del ácido bifenil-2-il-carbámico de formula (1), y a procedimientos para la preparacion de, a intermedios usados en la preparacion de, a composiciones que contienen y los usos de, dicho compuesto. También se refiere a los hidratos, solvatos y polimorfos. Es antagonista de receptores M3, util para enfermedades respiratorias.This refers to the hydrochloride salt of 1- {9 - [(3-fluoro-4-hydroxy-benzoyl) -methyl-amino] -nonyl} -piperidin-4-yl ester of biphenyl-2-yl-carbamic acid of formula (1), and processes for the preparation of, to intermediates used in the preparation of, to compositions containing and the uses of said compound. It also refers to hydrates, solvates and polymorphs. It is an antagonist of M3 receptors, useful for respiratory diseases.

ARP110100020A 2010-01-07 2011-01-05 CHLORHYDRATE SALT OF 1- (9 - ((3-FLUORO-4-HIDROXI-BENZOIL) -METIL-AMINO) -NONIL) -PIPERIDIN-4-IL ESTER OF ACID BIFENIL-2-IL-CARBAMICO AR079835A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US29297110P 2010-01-07 2010-01-07

Publications (1)

Publication Number Publication Date
AR079835A1 true AR079835A1 (en) 2012-02-22

Family

ID=43759799

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP110100020A AR079835A1 (en) 2010-01-07 2011-01-05 CHLORHYDRATE SALT OF 1- (9 - ((3-FLUORO-4-HIDROXI-BENZOIL) -METIL-AMINO) -NONIL) -PIPERIDIN-4-IL ESTER OF ACID BIFENIL-2-IL-CARBAMICO

Country Status (4)

Country Link
JP (1) JP2011153136A (en)
AR (1) AR079835A1 (en)
TW (1) TW201139375A (en)
WO (1) WO2011083387A1 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI2834244T1 (en) * 2012-03-13 2016-12-30 Respivert Limited Crystalline pi3 kinase inhibitors
SG11201902523UA (en) * 2016-10-20 2019-05-30 Pfizer Anti-proliferative agents for treating pah
ES2927715T3 (en) 2017-10-05 2022-11-10 Fulcrum Therapeutics Inc p38 kinase inhibitors reduce the expression of dux4 and the genes that follow it for the treatment of FSHD
US10342786B2 (en) 2017-10-05 2019-07-09 Fulcrum Therapeutics, Inc. P38 kinase inhibitors reduce DUX4 and downstream gene expression for the treatment of FSHD

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR0166088B1 (en) 1990-01-23 1999-01-15 . Derivatives of cyclodextrins exhibiting enhanced aqueous solubility and the use thereof
US5376645A (en) 1990-01-23 1994-12-27 University Of Kansas Derivatives of cyclodextrins exhibiting enhanced aqueous solubility and the use thereof
GB9711643D0 (en) 1997-06-05 1997-07-30 Janssen Pharmaceutica Nv Glass thermoplastic systems
GB0315509D0 (en) 2003-07-02 2003-08-06 Meridica Ltd Dispensing device
US7320990B2 (en) * 2004-02-13 2008-01-22 Theravance, Inc. Crystalline form of a biphenyl compound
WO2006099032A1 (en) * 2005-03-10 2006-09-21 Theravance, Inc. Biphenyl compounds useful as muscarinic receptor antagonists
JP2008538104A (en) 2005-03-10 2008-10-09 セラヴァンス， インコーポレーテッド Biphenyl compounds useful as muscarinic receptor antagonists
TWI372749B (en) * 2005-03-10 2012-09-21 Theravance Inc Crystalline forms of a biphenyl compound
PE20110312A1 (en) * 2008-07-15 2011-06-25 Pfizer Ltd PIPERIDINE ESTERS COMPOUNDS OF BIPHENYL-2-ILCARBAMIC ACID AS ANTAGONISTS OF THE MUSCARINIC M3 RECEPTOR

Also Published As

Publication number Publication date
WO2011083387A1 (en) 2011-07-14
JP2011153136A (en) 2011-08-11
TW201139375A (en) 2011-11-16

Similar Documents

Publication Publication Date Title
CU20130129A7 (en) QUINASE INHIBITORS RELATED TO PIRROLO [2,3-d] PIRIMIDINE TROPOMIOSINE
UY32490A (en) BETA-SECRETASA INHIBITORS
CU20110204A7 (en) SUBSTITUTED 1-CYANOETHYLETHYCLIC CARBOXAMIDE 750 COMPOUNDS
CU20110145A7 (en) SULFONAMIDE DERIVATIVES
CR20120628A (en) MORPHOLINOPIRIMIDINAS AND ITS USE IN THERAPY
ECSP12012174A (en) DERIVATIVES OF N- (IMIDAZOPIRIMIDIN-7-IL) -HETEROARILAMIDA AND ITS USE AS PDE10A INHIBITORS
CR20120264A (en) COMPOUNDS
UY31134A1 (en) PIPERIDINE / PIPERAZINE DERIVATIVES (I)
SV2009003400A (en) PIRIDINE DERIVATIVES
SV2011003802A (en) USEFUL TRIAZOL DERIVATIVES FOR THE TREATMENT OF DISEASES
SV2008003037A (en) AMINA DERIVATIVES
CR20140134A (en) PHARMACEUTICAL COMPOSITIONS
BRPI1012638B8 (en) methods and intermediates for preparing pharmaceutical agents
UY33337A (en) SUBSTITUTED DERIVATIVES OF 1H-PIRAZOL [3,4-d] PYRIMIDINE AS INHIBITORS OF PHOSFOINOSITIDE 3-KINASES
PE20151602A1 (en) SALTS OF DERIVATIVES OF 2-AMINO-1-HYDROXYETHYL-8-HYDROXYQUINOLIN-2 (1H) -ONE THAT HAVE AGONISTIC ACTIVITY OF THE B (beta) 2 ADRENERGIC RECEPTOR AS WELL AS ANTAGONIST ACTIVITY OF THE MUSCARINIC RECEPTOR M3
CU20130116A7 (en) HETEROARILO DERIVATIVES AS MODULATORS OF NACHR ALFA 7
SV2016005153A (en) COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF THE MEK
UA108378C2 (en) METHOD OF PREPARATION OF pleuromutilins
ECSP13012600A (en) CO-crystals and salts of CCR3 inhibitors
AR082968A1 (en) BICYCLE INHIBITORS OF NOTUM PECTINACETILESTERASE AND A PHARMACEUTICAL COMPOSITION BASED ON THE COMPOUND
GT201300322A (en) TYPICAL OPHTHALMOLOGICAL PHARMACEUTICAL COMPOSITION CONTAINING REGORAFENIB
AR079835A1 (en) CHLORHYDRATE SALT OF 1- (9 - ((3-FLUORO-4-HIDROXI-BENZOIL) -METIL-AMINO) -NONIL) -PIPERIDIN-4-IL ESTER OF ACID BIFENIL-2-IL-CARBAMICO
UY32744A (en) DERIVATIVES OF 2-CARBOXAMIDA-7-PIPERAZINIL-BENZOFURANO 774
ECSP13012548A (en) OXADIAZOL INHIBITORS OF LEUCOTRENE PRODUCTION.
SV2009003420A (en) NEW LIGHTING COMPOUNDS OF THE ADENOSINE A3 RECEIVER

Legal Events

Date Code Title Description
FA Abandonment or withdrawal