AR056749A1 - Formulaciones de dosificacion oral de ibuprofeno organolepticamente aceptables metodos para su preparacion y uso - Google Patents
Formulaciones de dosificacion oral de ibuprofeno organolepticamente aceptables metodos para su preparacion y usoInfo
- Publication number
- AR056749A1 AR056749A1 ARP060104770A ARP060104770A AR056749A1 AR 056749 A1 AR056749 A1 AR 056749A1 AR P060104770 A ARP060104770 A AR P060104770A AR P060104770 A ARP060104770 A AR P060104770A AR 056749 A1 AR056749 A1 AR 056749A1
- Authority
- AR
- Argentina
- Prior art keywords
- organoleptically
- preparation
- ibuprophen
- dosage formulations
- acceptable
- Prior art date
Links
- HEFNNWSXXWATRW-UHFFFAOYSA-N Ibuprofen Chemical compound CC(C)CC1=CC=C(C(C)C(O)=O)C=C1 HEFNNWSXXWATRW-UHFFFAOYSA-N 0.000 title abstract 3
- 239000000203 mixture Substances 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 2
- 238000002360 preparation method Methods 0.000 title abstract 2
- 238000009472 formulation Methods 0.000 abstract 2
- 229960001680 ibuprofen Drugs 0.000 abstract 2
- 230000000873 masking effect Effects 0.000 abstract 2
- 229920000858 Cyclodextrin Polymers 0.000 abstract 1
- 239000002826 coolant Substances 0.000 abstract 1
- 150000007524 organic acids Chemical class 0.000 abstract 1
- HFHDHCJBZVLPGP-UHFFFAOYSA-N schardinger α-dextrin Chemical compound O1C(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(O)C2O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC2C(O)C(O)C1OC2CO HFHDHCJBZVLPGP-UHFFFAOYSA-N 0.000 abstract 1
- 239000007787 solid Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/716—Glucans
- A61K31/724—Cyclodextrins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/534—Mentha (mint)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/04—Drugs for disorders of the respiratory system for throat disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/10—Expectorants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pulmonology (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Alternative & Traditional Medicine (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Medical Informatics (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Mycology (AREA)
- Physiology (AREA)
- Nutrition Science (AREA)
- Zoology (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Otolaryngology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
Abstract
Formulaciones de dosificacion oral solidas organolépticamente aceptables de ibuprofeno, y métodos para su preparacion y utilizacion. Una característica de las presentes formulaciones es que incluyen ibuprofeno y un componente de enmascaramiento. El componente de enmascaramiento incluye uno o más de un agente de enfriamiento, un ácido orgánico y una ciclodextrina. La presente encuentra utilidad en una variedad de aplicaciones.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US73312705P | 2005-11-02 | 2005-11-02 | |
US81041706P | 2006-06-01 | 2006-06-01 |
Publications (1)
Publication Number | Publication Date |
---|---|
AR056749A1 true AR056749A1 (es) | 2007-10-24 |
Family
ID=38023574
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP060104770A AR056749A1 (es) | 2005-11-02 | 2006-10-31 | Formulaciones de dosificacion oral de ibuprofeno organolepticamente aceptables metodos para su preparacion y uso |
Country Status (12)
Country | Link |
---|---|
US (1) | US20070098789A1 (es) |
EP (1) | EP1942877A4 (es) |
JP (2) | JP2009514857A (es) |
KR (1) | KR20080034166A (es) |
CN (1) | CN103622926A (es) |
AR (1) | AR056749A1 (es) |
AU (2) | AU2006312119B2 (es) |
BR (1) | BRPI0618273A2 (es) |
CA (1) | CA2620219A1 (es) |
RU (2) | RU2008116871A (es) |
TW (1) | TW200733954A (es) |
WO (1) | WO2007055887A1 (es) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
RU2008116871A (ru) * | 2005-11-02 | 2009-12-10 | ТЕЙКОКУ ФАРМА ЮЭсЭй, ИНК. (US) | Органолептически приемлемые пероральные лекарственные формы ибупрофена, способы их приготовления и применения |
US20080113021A1 (en) * | 2006-10-25 | 2008-05-15 | Robert Shen | Ibuprofen composition |
JP5821247B2 (ja) * | 2010-04-07 | 2015-11-24 | 大正製薬株式会社 | イブプロフェンの昇華抑制方法 |
JP6067676B2 (ja) * | 2011-04-11 | 2017-01-25 | アヤンダ グループ エーエス | 経口医薬分散組成物 |
CN102258490B (zh) * | 2011-07-01 | 2012-10-03 | 中美天津史克制药有限公司 | 布洛芬咀嚼片 |
US9914968B2 (en) | 2012-09-26 | 2018-03-13 | Cepheid | Honeycomb tube |
FR2997856B1 (fr) * | 2012-11-14 | 2015-04-24 | Pf Medicament | Pastille medicamenteuse a base d'ibuprofene sodique dihydrate |
CN103690474B (zh) * | 2013-12-04 | 2015-09-30 | 郑州大明药物科技有限公司 | 布洛芬乳膏的制备方法 |
Family Cites Families (35)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8623557D0 (en) * | 1986-10-01 | 1986-11-05 | Boots Co Plc | Therapeutic agents |
GB8813682D0 (en) * | 1988-06-09 | 1988-07-13 | Reckitt & Colmann Prod Ltd | Pharmaceutical compositions |
CH677606A5 (es) * | 1988-07-12 | 1991-06-14 | Aesculapius Pharma Sa | |
US4916161A (en) * | 1988-10-25 | 1990-04-10 | Bristol-Myers Squibb | Taste-masking pharmaceutical agents |
US5055461A (en) * | 1989-02-15 | 1991-10-08 | Richardson-Vicks Inc. | Anesthetic oral compositions and methods of use |
JPH0426618A (ja) * | 1990-05-21 | 1992-01-29 | Japan Tobacco Inc | トローチ剤 |
US5024997A (en) * | 1990-06-22 | 1991-06-18 | American Home Products Corporation | Palatable ibuprofen solutions |
DE69331839T2 (de) * | 1992-01-29 | 2002-12-12 | Takeda Chemical Industries, Ltd. | Schnellösliche Tablette und ihre Herstellung |
GB9207990D0 (en) * | 1992-04-10 | 1992-05-27 | Smithkline Beecham Plc | Pharmaceutical composition |
CA2161217A1 (en) * | 1993-04-30 | 1994-11-10 | Carmelita Macklin Russell | Coated pharmaceutical compositions |
US5866162A (en) * | 1993-08-10 | 1999-02-02 | Smithkline Beecham P.L.C. | Pharmaceutical composition containing a drug/β-cyclodextrin complex in combination with an acid-base couple |
US5616344A (en) * | 1994-06-14 | 1997-04-01 | Fuisz Technologies Ltd. | Apparatus and process for strengthening low density compression dosage units and product therefrom |
US5560913A (en) * | 1995-01-27 | 1996-10-01 | The Procter & Gamble Company | Pharmaceutical compositions |
TW442287B (en) * | 1995-06-13 | 2001-06-23 | American Home Produits Corp | Organoleptically acceptable oral pharmaceutical composition comprising the S(+)1,8-diethyl-1-1,3,4,9-tetrahydropyrano[3,4-b] indole-1-acetic acid (Etodolac) |
EP0769294B1 (en) * | 1995-10-17 | 2001-12-12 | Reckitt Benckiser Healthcare (UK) Limited | Taste-masked aqueous solutions comprising ibuprofen and menthol |
GB9523833D0 (en) * | 1995-11-22 | 1996-01-24 | Boots Co Plc | Medical treatment |
US5912007A (en) * | 1996-02-29 | 1999-06-15 | Warner-Lambert Company | Delivery system for the localized administration of medicaments to the upper respiratory tract and methods for preparing and using same |
WO1998002182A1 (en) * | 1996-07-12 | 1998-01-22 | Novartis Consumer Health S.A. | Oral pharmaceutical combinations of nsaids with terpenoids |
GB9710521D0 (en) * | 1997-05-22 | 1997-07-16 | Boots Co Plc | Process |
ES2224634T3 (es) * | 1998-04-29 | 2005-03-01 | Sumitomo Pharmaceuticals Company, Limited | Formulacion oral que comprende biguanida y un acido organico. |
US20020110581A1 (en) * | 1999-04-06 | 2002-08-15 | Ream Ronald L. | Over-coated product including consumable center and medicament |
US20050042271A1 (en) * | 1999-11-19 | 2005-02-24 | Xel Herbaceuticals, Inc . | Transdermal delivery system for alkaloids of aconitum species |
ES2171110B1 (es) * | 2000-03-03 | 2003-06-16 | Aplicaciones Farmacodinamicas | Composicion farmaceutica a base de ibuprofeno y procedimiento para su preparacion. |
WO2003009834A1 (en) * | 2000-08-17 | 2003-02-06 | Battey Alyce S | Oral delivery of pharmaceuticals via encapsulation |
PT1321140E (pt) * | 2000-08-25 | 2005-06-30 | Kowa Co | Solucoes de ibuprofeno para o enchimento de capsulas e preparacoes de capsula |
IT1319229B1 (it) * | 2000-10-20 | 2003-09-26 | Savio Macchine Tessili Spa | Dispositivo portarocche perfezionato per avvolgimento di filato conpressione regolata, particolarmente per ritorcitoi a doppia torsione. |
WO2002096406A1 (fr) * | 2001-05-25 | 2002-12-05 | Ssp Co., Ltd. | Compositions medicinales |
US8859028B2 (en) * | 2002-06-14 | 2014-10-14 | Cereal Ingredients, Inc. | Coated food particle and method for making a swirl |
GB0217382D0 (en) * | 2002-07-26 | 2002-09-04 | Pfizer Ltd | Process for making orally consumable dosage forms |
US20040071852A1 (en) * | 2002-10-09 | 2004-04-15 | Yael Vodovotz | Compositions and processes for making high soy protein-containing bakery products |
ATE372059T1 (de) * | 2002-10-11 | 2007-09-15 | Novozymes As | Verfahren zur herstellung von wärmebehandelten produkten |
JP4815867B2 (ja) * | 2004-05-11 | 2011-11-16 | 大正製薬株式会社 | 安定化された固形製剤 |
US20060263475A1 (en) * | 2004-08-25 | 2006-11-23 | Cadbury Adams Usa, Llc. | Center-filled chewing gum composition |
EP1835886A1 (en) * | 2004-12-23 | 2007-09-26 | Warner-Lambert Company LLC | Orally disintegrating pharmaceutical compositions with sensory cue agents |
RU2008116871A (ru) * | 2005-11-02 | 2009-12-10 | ТЕЙКОКУ ФАРМА ЮЭсЭй, ИНК. (US) | Органолептически приемлемые пероральные лекарственные формы ибупрофена, способы их приготовления и применения |
-
2006
- 2006-10-17 RU RU2008116871/15A patent/RU2008116871A/ru unknown
- 2006-10-17 BR BRPI0618273-9A patent/BRPI0618273A2/pt not_active IP Right Cessation
- 2006-10-17 CA CA002620219A patent/CA2620219A1/en not_active Abandoned
- 2006-10-17 KR KR1020087004052A patent/KR20080034166A/ko active Search and Examination
- 2006-10-17 WO PCT/US2006/041024 patent/WO2007055887A1/en active Application Filing
- 2006-10-17 CN CN201310629706.XA patent/CN103622926A/zh active Pending
- 2006-10-17 US US11/582,850 patent/US20070098789A1/en not_active Abandoned
- 2006-10-17 AU AU2006312119A patent/AU2006312119B2/en not_active Ceased
- 2006-10-17 EP EP06817206A patent/EP1942877A4/en not_active Withdrawn
- 2006-10-17 JP JP2008538910A patent/JP2009514857A/ja active Pending
- 2006-10-31 AR ARP060104770A patent/AR056749A1/es not_active Application Discontinuation
- 2006-11-01 TW TW095140338A patent/TW200733954A/zh unknown
-
2010
- 2010-05-20 AU AU2010202050A patent/AU2010202050A1/en not_active Abandoned
-
2012
- 2012-08-23 JP JP2012184203A patent/JP2012255018A/ja active Pending
- 2012-09-11 RU RU2012138581/15A patent/RU2012138581A/ru not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
AU2010202050A1 (en) | 2010-06-10 |
AU2006312119A1 (en) | 2007-05-18 |
JP2012255018A (ja) | 2012-12-27 |
JP2009514857A (ja) | 2009-04-09 |
BRPI0618273A2 (pt) | 2011-08-23 |
CN103622926A (zh) | 2014-03-12 |
RU2012138581A (ru) | 2014-03-20 |
WO2007055887A1 (en) | 2007-05-18 |
CA2620219A1 (en) | 2007-05-18 |
EP1942877A4 (en) | 2011-09-14 |
US20070098789A1 (en) | 2007-05-03 |
TW200733954A (en) | 2007-09-16 |
AU2006312119B2 (en) | 2010-04-29 |
RU2008116871A (ru) | 2009-12-10 |
EP1942877A1 (en) | 2008-07-16 |
KR20080034166A (ko) | 2008-04-18 |
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