AR056591A1 - Polipeptidos ligandos para receptor 4 simil toll (tlr4) - Google Patents

Polipeptidos ligandos para receptor 4 simil toll (tlr4)

Info

Publication number
AR056591A1
AR056591A1 ARP060104709A ARP060104709A AR056591A1 AR 056591 A1 AR056591 A1 AR 056591A1 AR P060104709 A ARP060104709 A AR P060104709A AR P060104709 A ARP060104709 A AR P060104709A AR 056591 A1 AR056591 A1 AR 056591A1
Authority
AR
Argentina
Prior art keywords
tlr4
polypeptides
toll
simil
receiver
Prior art date
Application number
ARP060104709A
Other languages
English (en)
Inventor
Valerie Odegar
Dennis William Powell
Original Assignee
Vaxinnate Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vaxinnate Corp filed Critical Vaxinnate Corp
Publication of AR056591A1 publication Critical patent/AR056591A1/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/06Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)

Abstract

La presente proporciona nuevos polipéptidos ligandos para el receptor 4 simil Toll (TLR4). Los nuevos ligandos polipeptídicos modulan la senalizacion de TLR4 y de esta manera regulan la Respuesta Inmune Innata. La presente proporciona métodos para modular la senalizacion de TLR4 empleando los polipéptidos ligandos TLR4 de la misma. La presente también proporciona vacunas que comprenden los nuevos polipéptidos ligandos de TLR4 y un antígeno. Proporciona además métodos para estimular una respuesta inmune empleando los polipéptidos polipeptídicos de TLR4 y vacunas de la misma.
ARP060104709A 2005-10-28 2006-10-27 Polipeptidos ligandos para receptor 4 simil toll (tlr4) AR056591A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US73159505P 2005-10-28 2005-10-28

Publications (1)

Publication Number Publication Date
AR056591A1 true AR056591A1 (es) 2007-10-10

Family

ID=38006399

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP060104709A AR056591A1 (es) 2005-10-28 2006-10-27 Polipeptidos ligandos para receptor 4 simil toll (tlr4)

Country Status (2)

Country Link
AR (1) AR056591A1 (es)
WO (1) WO2007053455A2 (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2638760A1 (en) 2006-03-07 2007-09-13 Vaxinnate Corporation Compositions that include hemagglutinin, methods of making and methods of use thereof
US7629135B2 (en) 2006-12-22 2009-12-08 The Board Of Trustees Of The University Of Illinois Toll-like receptor agonists and antagonists and methods of use thereof
AU2013229432A1 (en) 2012-03-08 2014-10-16 Novartis Ag Adjuvanted formulations of booster vaccines
CN104159603A (zh) 2012-03-08 2014-11-19 诺华股份有限公司 带有tlr4激动剂的联合疫苗
WO2013148072A1 (en) 2012-03-28 2013-10-03 University Of Maryland Administration of eritoran or pharmaceutically acceptable salts thereof to treat orthomyxovirus infections
RU2015106930A (ru) 2012-09-06 2016-10-20 Новартис Аг Комбинированные вакцины с менингококком серогруппы в и к/д/с
KR20150065878A (ko) 2012-10-12 2015-06-15 글락소스미스클라인 바이오로지칼즈 에스.에이. 조합 백신에서 사용하기 위한 가교되지 않은 무세포 백일해 항원
US9827190B2 (en) 2013-02-01 2017-11-28 Glaxosmithkline Biologicals Sa Intradermal delivery of immunological compositions comprising toll-like receptor 7 agonists
WO2014184683A2 (en) * 2013-04-26 2014-11-20 Oslo Universitetssykehus Hf Compositions and methods for targeting antigen-presenting cells
CN109310730A (zh) * 2016-02-17 2019-02-05 佩普蒂康姆有限责任公司 Tlr4活化的肽激动剂和拮抗剂
AU2019216873A1 (en) * 2018-02-07 2020-08-20 Imugene Limited A vaccine composition and uses thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090087878A9 (en) * 1999-05-06 2009-04-02 La Rosa Thomas J Nucleic acid molecules associated with plants

Also Published As

Publication number Publication date
WO2007053455A2 (en) 2007-05-10
WO2007053455A3 (en) 2007-06-14

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