AR056591A1 - LIGHT POLYPEPTIDES FOR RECEIVER 4 SIMIL TOLL (TLR4) - Google Patents
LIGHT POLYPEPTIDES FOR RECEIVER 4 SIMIL TOLL (TLR4)Info
- Publication number
- AR056591A1 AR056591A1 ARP060104709A ARP060104709A AR056591A1 AR 056591 A1 AR056591 A1 AR 056591A1 AR P060104709 A ARP060104709 A AR P060104709A AR P060104709 A ARP060104709 A AR P060104709A AR 056591 A1 AR056591 A1 AR 056591A1
- Authority
- AR
- Argentina
- Prior art keywords
- tlr4
- polypeptides
- toll
- simil
- receiver
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
Abstract
La presente proporciona nuevos polipéptidos ligandos para el receptor 4 simil Toll (TLR4). Los nuevos ligandos polipeptídicos modulan la senalizacion de TLR4 y de esta manera regulan la Respuesta Inmune Innata. La presente proporciona métodos para modular la senalizacion de TLR4 empleando los polipéptidos ligandos TLR4 de la misma. La presente también proporciona vacunas que comprenden los nuevos polipéptidos ligandos de TLR4 y un antígeno. Proporciona además métodos para estimular una respuesta inmune empleando los polipéptidos polipeptídicos de TLR4 y vacunas de la misma.This provides new ligand polypeptides for the 4-like Toll receptor (TLR4). The new polypeptide ligands modulate the signaling of TLR4 and thus regulate the Innate Immune Response. This provides methods to modulate TLR4 signaling using TLR4 ligand polypeptides thereof. This also provides vaccines comprising the new TLR4 ligand polypeptides and an antigen. It also provides methods to stimulate an immune response using TLR4 polypeptide polypeptides and vaccines thereof.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US73159505P | 2005-10-28 | 2005-10-28 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR056591A1 true AR056591A1 (en) | 2007-10-10 |
Family
ID=38006399
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP060104709A AR056591A1 (en) | 2005-10-28 | 2006-10-27 | LIGHT POLYPEPTIDES FOR RECEIVER 4 SIMIL TOLL (TLR4) |
Country Status (2)
| Country | Link |
|---|---|
| AR (1) | AR056591A1 (en) |
| WO (1) | WO2007053455A2 (en) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106237316A (en) | 2006-03-07 | 2016-12-21 | 法克斯因内特公司 | The compositions comprising hemagglutinin, the method manufacturing it and the method using it |
| US7629135B2 (en) | 2006-12-22 | 2009-12-08 | The Board Of Trustees Of The University Of Illinois | Toll-like receptor agonists and antagonists and methods of use thereof |
| EP2822584A1 (en) | 2012-03-08 | 2015-01-14 | Novartis AG | Combination vaccines with tlr4 agonists |
| MX2014010417A (en) | 2012-03-08 | 2014-09-22 | Novartis Ag | Adjuvanted formulations of booster vaccines. |
| AU2013240456B2 (en) | 2012-03-28 | 2017-04-13 | University Of Maryland, Baltimore | Administration of eritoran or pharmaceutically acceptable salts thereof to treat orthomyxovirus infections |
| EP2892553A1 (en) | 2012-09-06 | 2015-07-15 | Novartis AG | Combination vaccines with serogroup b meningococcus and d/t/p |
| CA2886938A1 (en) | 2012-10-12 | 2014-04-17 | Glaxosmithkline Biologicals S.A. | Non-cross-linked acellular pertussis antigens for use in combination vaccines |
| EP2950819B1 (en) | 2013-02-01 | 2018-03-28 | GlaxoSmithKline Biologicals SA | Intradermal delivery of immunological compositions comprising toll-like receptor agonists |
| WO2014184683A2 (en) * | 2013-04-26 | 2014-11-20 | Oslo Universitetssykehus Hf | Compositions and methods for targeting antigen-presenting cells |
| EP3416667A4 (en) | 2016-02-17 | 2020-02-26 | Pepticom Ltd | Peptide agonists and antagonists of tlr4 activation |
| EP3749356A4 (en) * | 2018-02-07 | 2021-11-24 | Imugene Limited | A vaccine composition and uses thereof |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20090087878A9 (en) * | 1999-05-06 | 2009-04-02 | La Rosa Thomas J | Nucleic acid molecules associated with plants |
-
2006
- 2006-10-27 AR ARP060104709A patent/AR056591A1/en unknown
- 2006-10-27 WO PCT/US2006/042051 patent/WO2007053455A2/en active Application Filing
Also Published As
| Publication number | Publication date |
|---|---|
| WO2007053455A2 (en) | 2007-05-10 |
| WO2007053455A3 (en) | 2007-06-14 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FB | Suspension of granting procedure |