AR053360A1 - Formulaciones novedosas de vacunas - Google Patents

Formulaciones novedosas de vacunas

Info

Publication number
AR053360A1
AR053360A1 ARP060101492A ARP060101492A AR053360A1 AR 053360 A1 AR053360 A1 AR 053360A1 AR P060101492 A ARP060101492 A AR P060101492A AR P060101492 A ARP060101492 A AR P060101492A AR 053360 A1 AR053360 A1 AR 053360A1
Authority
AR
Argentina
Prior art keywords
oil
water
ionic
vaccines
immunogen
Prior art date
Application number
ARP060101492A
Other languages
English (en)
Inventor
Alexis Guy Andre Parisot
Stephanie Desgouilles-Blechet
Catherine Charreyre
Claude Jean Marie Roulet
Original Assignee
Merial Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merial Ltd filed Critical Merial Ltd
Publication of AR053360A1 publication Critical patent/AR053360A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Dispersion Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Cosmetics (AREA)

Abstract

Emulsiones aceite en agua, su uso como adyuvantes y composiciones farmacéuticas inmunologicas o de vacuna que las pueden comprender. En una realizacion, la emulsion aceite en agua (O/W) puede comprender una solucion acuosa que contiene un inmunogeno, un aceite mineral, un alcohol graso etoxilado lipofilo no ionico y un surfactante hidrofilo no ionico. En otra realizacion, la emulsion aceite en agua (O/W) puede comprender una solucion acuosa que contiene un inmunogeno, un surfactante lipofilo no ionico, un aceite mineral y un alcohol graso etoxilado hidrofilo no ionico. También comprende un método para preparar una composicion de vacuna, que utiliza el adyuvante de la presente solicitud, la composicion de vacuna obtenida y métodos de uso.
ARP060101492A 2005-04-15 2006-04-17 Formulaciones novedosas de vacunas AR053360A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US11/107,000 US7691368B2 (en) 2005-04-15 2005-04-15 Vaccine formulations

Publications (1)

Publication Number Publication Date
AR053360A1 true AR053360A1 (es) 2007-05-02

Family

ID=36950184

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP060101492A AR053360A1 (es) 2005-04-15 2006-04-17 Formulaciones novedosas de vacunas

Country Status (25)

Country Link
US (1) US7691368B2 (es)
EP (2) EP1888107B1 (es)
JP (1) JP5093902B2 (es)
KR (1) KR101292874B1 (es)
CN (1) CN101184501A (es)
AR (1) AR053360A1 (es)
AU (2) AU2006236711B2 (es)
BR (1) BRPI0610633B1 (es)
CA (1) CA2604432C (es)
CY (1) CY1113104T1 (es)
DK (1) DK1888107T3 (es)
ES (1) ES2389377T3 (es)
HK (1) HK1116085A1 (es)
IL (1) IL186600A (es)
MX (1) MX2007012785A (es)
MY (1) MY144189A (es)
NZ (2) NZ584420A (es)
PL (1) PL1888107T3 (es)
PT (1) PT1888107E (es)
RU (1) RU2422155C2 (es)
SI (1) SI1888107T1 (es)
TW (1) TWI376232B (es)
UA (1) UA94404C2 (es)
WO (1) WO2006113373A2 (es)
ZA (1) ZA200708634B (es)

Families Citing this family (114)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UA95602C2 (ru) 2004-12-30 2011-08-25 Берингер Ингельхейм Ветмедика, Инк. Иммуногенная композиция цвс2 и способы приготовления такой композиции
US7833707B2 (en) * 2004-12-30 2010-11-16 Boehringer Ingelheim Vetmedica, Inc. Methods of overexpression and recovery of porcine circovirus type 2 ORF2
US7700285B1 (en) 2005-12-29 2010-04-20 Boehringer Ingelheim Vetmedica, Inc. PCV2 immunogenic compositions and methods of producing such compositions
US8703095B2 (en) 2005-07-07 2014-04-22 Sanofi Pasteur S.A. Immuno-adjuvant emulsion
EP1926496B1 (en) * 2005-09-09 2013-06-26 Intervet International B.V. Pcv-2 vaccine
JP2009514850A (ja) 2005-11-04 2009-04-09 ノバルティス ヴァクシンズ アンド ダイアグノスティクス エスアールエル アジュバントとして減少した量の水中油型エマルションを有するインフルエンザワクチン
AU2006310337B9 (en) 2005-11-04 2013-11-28 Novartis Ag Adjuvanted influenza vaccines including cytokine-inducing agents
JP2009514838A (ja) 2005-11-04 2009-04-09 ノバルティス ヴァクシンズ アンド ダイアグノスティクス エスアールエル 細胞培養物において増殖されたインフルエンザウイルスから調製された非ビリオン抗原を含むアジュバントワクチン
MY149398A (en) * 2005-12-29 2013-08-30 Boehringer Ingelheim Vetmed Multivalent pcv2 immunogenic compositions and methods of producing such compositions
MX2008008311A (es) * 2005-12-29 2009-03-04 Boehringer Ingelheim Vetmed Uso de una composicion inmunogenica de pcv2 para reducir los sintomas clinicos en cerdos.
FR2896162B1 (fr) 2006-01-13 2008-02-15 Sanofi Pasteur Sa Emulsion huile dans eau thermoreversible
EP1991262A4 (en) * 2006-03-03 2009-11-04 Merial Ltd MYCOPLASMA HYOPNEUMONIAE VACCINE
EP2004226A1 (en) 2006-03-24 2008-12-24 Novartis Vaccines and Diagnostics GmbH & Co. KG Storage of influenza vaccines without refrigeration
GB0614460D0 (en) 2006-07-20 2006-08-30 Novartis Ag Vaccines
BRPI0716536A2 (pt) 2006-09-11 2013-09-24 Novartis Ag produÇço de vacinas de vÍrus influenza, sem a utilizaÇço de ovos
US20100136060A1 (en) * 2006-11-22 2010-06-03 Boehringer Ingelheim Vetmedica, Inc. Methods of reducing porcine circovirus-associated disease outbreaks
CA2671629C (en) 2006-12-06 2017-08-15 Novartis Ag Vaccines including antigen from four strains of influenza virus
EP2101815A4 (en) 2006-12-11 2010-10-06 Boehringer Ingelheim Vetmed EFFICIENT PROCESS FOR THE TREATMENT OF PORCINE CIRCOVIRUS AND LAWSONIA INTRACELLULARIS INFECTIONS
US8865183B2 (en) 2006-12-15 2014-10-21 Boehringer Ingelheim Vetmedica, Inc. Treatment of pigs with PCV2 antigent
EP1941903A1 (en) 2007-01-03 2008-07-09 Boehringer Ingelheim Vetmedica Gmbh Prophylaxis and treatment of PRDC
EP1958644A1 (en) 2007-02-13 2008-08-20 Boehringer Ingelheim Vetmedica Gmbh Prevention and treatment of sub-clinical pcvd
KR20150082667A (ko) 2007-04-06 2015-07-15 인비라젠 인코포레이티드 살아있는 약독화된 바이러스를 위한 방법 및 조성물
WO2009001217A2 (en) 2007-06-27 2008-12-31 Novartis Ag Low-additive influenza vaccines
US20090017064A1 (en) * 2007-07-10 2009-01-15 Wyeth Methods and Compositions for Immunizing Pigs Against Porcine Circovirus
GB0714963D0 (en) 2007-08-01 2007-09-12 Novartis Ag Compositions comprising antigens
US7829274B2 (en) * 2007-09-04 2010-11-09 Boehringer Ingelheim Vetmedica, Inc. Reduction of concomitant infections in pigs by the use of PCV2 antigen
AU2008313424B2 (en) 2007-10-19 2014-05-22 Novartis Ag Meningococcal vaccine formulations
GB0810305D0 (en) 2008-06-05 2008-07-09 Novartis Ag Influenza vaccination
CN106562927A (zh) * 2007-12-21 2017-04-19 硕腾服务有限责任公司 经热处理的菌苗，及由这些经热处理的菌苗制备的乳剂疫苗
US20110020394A1 (en) * 2007-12-31 2011-01-27 Boehringer Ingelheim Vetmedica, Inc. Pcv2 orf2 virus like particle with foreign amino acid insertion
KR20100113582A (ko) 2008-01-23 2010-10-21 베링거잉겔하임베트메디카인코퍼레이티드 Ｐｃｖ2 마이코플라즈마 히오뉴모니에 면역원성 조성물 및 당해 조성물의 생산 방법
ES2535101T3 (es) 2008-03-18 2015-05-05 Novartis Ag Mejoras en la preparación de antígenos en vacuna de virus de la gripe
AU2009277107B2 (en) * 2008-07-30 2014-02-27 University Of Kentucky Research Foundation Equine disease model for herpesvirus neurologic disease and uses thereof
WO2010032138A2 (en) 2008-09-18 2010-03-25 Novartis Ag Vaccine adjuvant combinations
MX2011005604A (es) 2008-11-28 2011-09-01 Merial Ltd Vacuna recombinante para influenza aviar y sus usos.
ES2608841T3 (es) 2009-02-10 2017-04-17 Seqirus UK Limited Vacunas contra la gripe con cantidades reducidas de escualeno
US20120093860A1 (en) 2009-02-10 2012-04-19 Novartis Ag Influenza vaccines with increased amounts of h3 antigen
ES2552383T3 (es) 2009-02-10 2015-11-27 Novartis Ag Regímenes de vacuna de la gripe para cepas asociadas a pandemias
CA2754618A1 (en) 2009-03-06 2010-09-10 Novartis Ag Chlamydia antigens
EP2228054A1 (en) * 2009-03-13 2010-09-15 ITALFARMACO S.p.A. Riluzole aqueous suspensions
BRPI1009829A2 (pt) 2009-03-24 2016-11-16 Novartis Ag combinações de proteína de ligação de fator h meningocócico e conjugados de sacarídeos pneumocócicos
RU2508126C2 (ru) 2009-04-14 2014-02-27 Новартис Аг Композиции для иммунизации против staphylococcus aureus
ES2579935T3 (es) * 2009-05-19 2016-08-17 Bioproperties Pty Ltd Cepa de vacuna de Mycoplasma Hyopneumoniae sensible a temperatura y uso de la misma
JP5836266B2 (ja) 2009-05-21 2015-12-24 ノバルティス アーゲー 非内因性ｐｏｌＩプロモーターを使用した逆遺伝学
US20120237545A1 (en) 2009-05-29 2012-09-20 Norvartis Ag Assays for influenza virus hemagglutinins
WO2011004263A2 (en) 2009-07-07 2011-01-13 Novartis Ag Conserved escherichia coli immunogens
CA2768343A1 (en) 2009-07-16 2011-01-20 Novartis Ag Detoxified escherichia coli immunogens
CN102482646B (zh) * 2009-07-31 2015-09-16 加拿大国家研究委员会 幽门螺杆菌脂多糖外部核心表位
AR078253A1 (es) * 2009-09-02 2011-10-26 Boehringer Ingelheim Vetmed Metodos para reducir la actividad antivirica en composiciones pcv-2 y composiciones pcv-2 con mejor inmunogenicidad
ES2600929T3 (es) * 2009-09-10 2017-02-13 Merial, Inc. Nuevas formulaciones de vacuna que comprenden adyuvantes que contienen saponina
JP2013504556A (ja) 2009-09-10 2013-02-07 ノバルティス アーゲー 気道疾患に対する組み合わせワクチン
GB0917003D0 (en) 2009-09-28 2009-11-11 Novartis Vaccines Inst For Global Health Srl Purification of bacterial vesicles
GB0917002D0 (en) 2009-09-28 2009-11-11 Novartis Vaccines Inst For Global Health Srl Improved shigella blebs
WO2011039631A2 (en) 2009-09-30 2011-04-07 Novartis Ag Expression of meningococcal fhbp polypeptides
GB0918392D0 (en) 2009-10-20 2009-12-02 Novartis Ag Diagnostic and therapeutic methods
AU2010309404B2 (en) 2009-10-20 2015-07-09 Seqirus UK Limited Improved reverse genetics methods for virus rescue
GB0919690D0 (en) 2009-11-10 2009-12-23 Guy S And St Thomas S Nhs Foun compositions for immunising against staphylococcus aureus
WO2011080595A2 (en) 2009-12-30 2011-07-07 Novartis Ag Polysaccharide immunogens conjugated to e. coli carrier proteins
GB201003333D0 (en) 2010-02-26 2010-04-14 Novartis Ag Immunogenic proteins and compositions
CA2793510A1 (en) 2010-03-18 2012-02-16 Novartis Ag Adjuvanted vaccines for serogroup b meningococcus
FR2957933B1 (fr) * 2010-03-24 2012-04-27 Seppic Sa Vaccin vivant pour maladies aviaires
GB201005625D0 (en) 2010-04-01 2010-05-19 Novartis Ag Immunogenic proteins and compositions
EP2556151A1 (en) 2010-04-07 2013-02-13 Novartis AG Method for generating a parvovirus b19 virus-like particle
US9555093B2 (en) 2010-04-30 2017-01-31 Temasek Life Sciences Laboratory Limited Universal vaccine against H5N1 lineages
WO2011141443A1 (en) * 2010-05-11 2011-11-17 Intervet International B.V. Vaccine against mycoplasma hyopneumoniae, suitable for administration in the presence of maternally derived antibodies
JP5876036B2 (ja) 2010-05-21 2016-03-02 ノバルティス アーゲー インフルエンザウイルス再集合方法
GB201009861D0 (en) 2010-06-11 2010-07-21 Novartis Ag OMV vaccines
WO2011161653A1 (en) 2010-06-25 2011-12-29 Novartis Ag Combinations of meningococcal factor h binding proteins
AU2011276328C1 (en) 2010-07-06 2016-01-21 Novartis Ag Norovirus derived immunogenic compositions and methods
GB201017519D0 (en) 2010-10-15 2010-12-01 Novartis Vaccines Inst For Global Health S R L Vaccines
WO2012072769A1 (en) 2010-12-01 2012-06-07 Novartis Ag Pneumococcal rrgb epitopes and clade combinations
US20140112950A1 (en) 2011-03-02 2014-04-24 Manmohan Singh Combination vaccines with lower doses of antigen and/or adjuvant
US10030052B2 (en) 2011-07-25 2018-07-24 Glaxosmithkline Biologicals Sa Parvovirus Vp1 unique region polypeptides and compositions thereof
US9358284B2 (en) 2011-09-14 2016-06-07 Glaxosmithkline Biologicals Sa Methods for making saccharide-protein glycoconjugates
EP2768528A1 (en) 2011-10-20 2014-08-27 Novartis AG Adjuvanted influenza b virus vaccines for pediatric priming
US20140335507A1 (en) 2011-12-12 2014-11-13 Novartis Ag Assays for influenza virus hemagglutinins
US20150044251A1 (en) 2011-12-23 2015-02-12 Novartis Ag Stable compositions for immunising against staphylococcus aureus
US9446117B2 (en) * 2012-02-14 2016-09-20 Merial, Inc. Rotavirus subunit vaccines and methods of making and use thereof
CA2813723A1 (en) 2012-03-02 2013-09-02 Novartis Ag Influenza virus reassortment
AU2013270793A1 (en) 2012-06-04 2014-12-11 Novartis Ag Improved safety testing
PL2890394T3 (pl) 2012-08-31 2019-12-31 Glaxosmithkline Biologicals Sa Stabilizowane białka do immunizacji przeciw staphylococcus aureus
JP2015528456A (ja) 2012-08-31 2015-09-28 ノバルティス アーゲー Ｓｔａｐｈｙｌｏｃｏｃｃｕｓａｕｒｅｕｓに対する免疫化のための安定化されたタンパク質
WO2014039978A2 (en) 2012-09-10 2014-03-13 Szathmary Dr Susan Vaccine to prevent mycoplasmal infection in waterfowl
EP3400960A1 (en) 2012-09-18 2018-11-14 GlaxoSmithKline Biologicals S.A. Outer membrane vesicles
TR201808684T4 (tr) 2012-10-02 2018-07-23 Glaxosmithkline Biologicals Sa Lineer olmayan sakarit konjügatları.
GB201218195D0 (en) 2012-10-10 2012-11-21 Istituto Zooprofilattico Sperimentale Delle Venezie Composition
JP6340011B2 (ja) 2012-11-30 2018-06-06 グラクソスミスクライン バイオロジカルズ ソシエテ アノニム シュードモナス抗原および抗原の組み合わせ
MX2015006927A (es) 2012-12-03 2016-02-05 Novartis Ag Redistribucion de virus de la influenza.
JP6525469B2 (ja) 2013-03-13 2019-06-05 ノバルティス アーゲー インフルエンザｂ型ウイルス再集合
EP2994162B1 (en) 2013-05-08 2021-04-07 Pharmgate Biologics Inc. Vaccine for pcv2 and mycoplasma
KR20160030097A (ko) 2013-05-10 2016-03-16 노파르티스 아게 인플루엔자 백신에서 기면증 위험의 방지
DE202013005130U1 (de) 2013-06-05 2013-09-10 Novartis Ag Influenza Virus Reassortierung
DE202013005100U1 (de) 2013-06-05 2013-08-26 Novartis Ag Influenza Virus Reassortierung
CA2914604A1 (en) 2013-06-06 2014-12-11 Novartis Ag Influenza virus reassortment
US9505808B2 (en) 2013-10-02 2016-11-29 Boehringer Ingelheim Vetmedica, Inc. PCV2 ORF2 protein variant and virus like particles composed thereof
MX369039B (es) * 2013-12-03 2019-10-25 Intervet Int Bv Vacuna contra el circovirus porcino tipo 2.
CN103751779A (zh) * 2014-02-25 2014-04-30 中国农业科学院上海兽医研究所 O型***多肽的泊洛沙姆凝胶佐剂
PT3122378T (pt) 2014-03-26 2020-03-04 Glaxosmithkline Biologicals Sa Antigénios estafilocócicos mutantes
WO2015179412A1 (en) 2014-05-19 2015-11-26 Merial, Inc. Recombinant spike protein subunit based vaccine for porcine epidemic diarrhea virus (pedv)
US20150359880A1 (en) * 2014-06-16 2015-12-17 Biomune Company Dual adjuvant vaccine compositions, preparation and uses
CN105267963A (zh) * 2014-06-18 2016-01-27 潘皓 纳米乳疫苗辅剂的制备方法
JP2015120709A (ja) * 2015-01-09 2015-07-02 ラボラトリオ アヴィメキシコ エスエー ディーイー シーヴィーＬａｂｏｒａｔｏｒｉｏ Ａｖｉ−Ｍｅｘ，Ｓ．Ａ． Ｄｅ Ｃ．Ｖ． 遺伝子組み換え不活性化ウィルスベクターワクチン
MX2017016896A (es) 2015-06-26 2018-04-10 Merial Inc Vacunas inactivadas contra la influenza canina, metodos para elaborarlas y sus usos.
WO2016207853A2 (en) 2015-06-26 2016-12-29 Seqirus UK Limited Antigenically matched influenza vaccines
JP6830070B2 (ja) 2015-07-07 2021-02-17 セキラス ユーケー リミテッドＳｅｑｉｒｕｓ ＵＫ Ｌｉｍｉｔｅｄ インフルエンザ効力アッセイ
CA3001340A1 (en) 2015-10-08 2017-04-13 Merial, Inc. Live attenuated heterologous vaccine for leptospira
MA42640B1 (fr) 2015-11-23 2021-06-30 Merial Inc Protéines de fusion de dmdv et e2 et leurs utilisations
TWI760322B (zh) 2016-01-29 2022-04-11 美商百靈佳殷格翰動物保健美國有限公司 重組腺病毒載體裝載之fmdv疫苗及其用途
JOP20190088A1 (ar) 2016-10-21 2019-04-21 Us Agriculture نواقل مؤتلفة للتعبير عن مولدات مضاد فيروس انفلونزا الطيور و استخداماتها
JP7174698B2 (ja) * 2016-11-29 2022-11-17 インターベット インターナショナル ベー． フェー． ブタワクチン
KR20230170803A (ko) 2016-12-14 2023-12-19 뵈링거 잉겔하임 애니멀 헬스 유에스에이 인코포레이티드 조류 병원체의 다중 항원을 발현하는 재조합 hvt 벡터 및 그를 포함하는 백신
FR3092754B1 (fr) * 2019-02-18 2022-06-03 Total Marketing Services Composition adjuvante pour vaccin
KR20220128613A (ko) 2019-11-18 2022-09-21 세퀴러스 피티와이 리미티드 재배열 인플루엔자 바이러스의 제조 방법
CN113546162B (zh) * 2021-05-31 2023-07-18 江苏省农业科学院 一种支原体疫苗及其制备方法

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5250289A (en) 1987-07-24 1993-10-05 The Boots Company Plc Sunscreen compositions
US5376369A (en) * 1987-11-03 1994-12-27 Syntex (U.S.A.) Inc. Vaccine adjuvant
PL155558B1 (pl) * 1988-01-28 1991-12-31 Inst Ciezkiej Syntezy Orga Sposób wytwarzania kompozycji emulgującej
AU657907B2 (en) 1990-05-29 1995-03-30 Wyeth Holdings Corporation Mycoplasma hyopneumoniae vaccine
US6197311B1 (en) * 1991-07-25 2001-03-06 Idec Pharmaceuticals Corporation Induction of cytotoxic T-lymphocyte responses
US5846805A (en) 1991-08-26 1998-12-08 Boehringer Ingelheim Animal Health, Inc. Culture of swine infertility and respiratory syndrome virus in simian cells
US5338543A (en) 1992-02-27 1994-08-16 Ambico, Inc. Thimerosal inactivated mycoplasma hyopneumoniae vaccine
US5695766A (en) 1992-10-30 1997-12-09 Iowa State University Research Foundation Highly virulent porcine reproductive and respiratory syndrome viruses which produce lesions in pigs and vaccines that protect pigs against said syndrome
DE69426228T2 (de) 1993-02-08 2001-03-01 Bayer Ag Verfahren zum Vermehren des das Reproduktions- und Atemwegs-Syndrom verursachenden Schweinevirus und dessen Verwendung als Impfstoff.
FR2723740B1 (fr) 1994-08-16 1996-11-08 Pasteur Merieux Serums Vacc Procede de preparation d'antigenes du virus grippal, antigenes obtenus et leurs applications
US5985177A (en) 1995-12-14 1999-11-16 Shiseido Co., Ltd. O/W/O type multiple emulsion and method of preparing the same
US5866401A (en) 1996-03-01 1999-02-02 Schering Corporation Porcine reproductive and respiratory syndrome vaccine
US5980912A (en) 1997-03-25 1999-11-09 Zonagen, Inc. Chitosan induced immunopotentiation
US6391314B1 (en) 1997-10-03 2002-05-21 Merial Porcine circoviruses vaccines diagnostic reagents
US20030165545A1 (en) * 2002-01-30 2003-09-04 Allergan, Inc. Ophthalmic compositions including oil-in-water emulsions, and methods for making and using same
WO2005009462A2 (en) * 2003-07-24 2005-02-03 Merial Limited Vaccine formulations comprising an oil-in-water emulsion
US9390965B2 (en) 2013-12-20 2016-07-12 Taiwan Semiconductor Manufacturing Co., Ltd. Air-gap forming techniques for interconnect structures

Also Published As

Publication number Publication date
RU2007142202A (ru) 2009-05-20
IL186600A0 (en) 2008-01-20
WO2006113373A3 (en) 2007-02-01
ZA200708634B (en) 2008-10-29
AU2010206041B2 (en) 2012-08-02
MY144189A (en) 2011-08-15
RU2422155C2 (ru) 2011-06-27
TWI376232B (en) 2012-11-11
EP1888107B1 (en) 2012-06-13
BRPI0610633A2 (pt) 2010-07-13
NZ584420A (en) 2011-11-25
NZ562663A (en) 2010-04-30
PL1888107T3 (pl) 2012-11-30
AU2006236711B2 (en) 2010-07-29
JP2008536860A (ja) 2008-09-11
TW200716165A (en) 2007-05-01
US20060233831A1 (en) 2006-10-19
HK1116085A1 (en) 2008-12-19
DK1888107T3 (da) 2012-07-23
CY1113104T1 (el) 2016-04-13
IL186600A (en) 2014-05-28
UA94404C2 (ru) 2011-05-10
KR20070122550A (ko) 2007-12-31
MX2007012785A (es) 2008-01-11
ES2389377T3 (es) 2012-10-25
AU2010206041A1 (en) 2010-08-19
SI1888107T1 (sl) 2012-09-28
CA2604432C (en) 2013-06-11
AU2006236711A1 (en) 2006-10-26
EP1888107A2 (en) 2008-02-20
CN101184501A (zh) 2008-05-21
WO2006113373A2 (en) 2006-10-26
US7691368B2 (en) 2010-04-06
BRPI0610633B1 (pt) 2021-07-20
EP2422809A1 (en) 2012-02-29
JP5093902B2 (ja) 2012-12-12
CA2604432A1 (en) 2006-10-26
KR101292874B1 (ko) 2013-08-05
PT1888107E (pt) 2012-07-26

Similar Documents

Publication Publication Date Title
AR053360A1 (es) Formulaciones novedosas de vacunas
ES2585810T3 (es) Uso de un virus de la gripe y un adyuvante de emulsión de aceite en agua para inducir respuesta de células T CD4 y/o una respuesta de células B de memoria mejorada
AR121096A2 (es) Formulaciones de vacunas que comprenden adyuvantes con saponina
CO6251369A2 (es) Vacuna de influenza de emulsion de aceite en agua
AR054822A1 (es) Emulsion inmuno adyuvante
NO20091022L (no) Vaksine omfattende en olje i vann emulsjons-adjuvant
BRPI0000126B8 (pt) composição de vacina, composição adjuvante e método de produção de uma composição de vacina
NO20090062L (no) Influensavaksine
CO6251273A2 (es) Composiciones para vacuna en emulsion que comprenden antigeno y un adyuvante en la fase acuosa y su metodo de elaboracion
NO20082472L (no) Vaksinesammensetninger omfattende en saponin adjuvant
AR075437A1 (es) Composicion inmunogenica que comprende al menos un antigeno del virus del dengue inactivado y un adyuvante sin aluminio, metodo para producir dicha vacuna y su uso para preparar un medicamento
EP2377551A3 (en) Adjuvanted influenza vaccines including cytokine-inducing agents
CL2015001111A1 (es) Composición coadyuvante que comprende un hidrato de carbono unido al quitosano formando una base de schiff; formulación de vacuna que la comprende; método de elaboración; y uso de la vacuna.
BR112023019301A2 (pt) Formulações de vacina de coronavírus
UY32930A (es) Composiciones que comprenden adyuvante, macrolido y antigeno proteico y procedimientos de uso de las mismas
UY29523A1 (es) Formulaciones de vacunas novedosas
CY1113746T1 (el) Εμβολιο που περιλαμβανει ανοσοενισχυτικο γαλακτωμα ελαιου σε υδωρ
TH68146B (th) สูตรผสมวัคซีนชนิดใหม่
TH122323A (th) สูตรผสมวัคซีนชนิดใหม่
AR111910A2 (es) Composición inmunogénica que comprende una formulación de adyuvante, composición de vacuna, procedimiento, usos, métodos
UY29429A1 (es) Composición inmunogénica que contiene virus de la gripe o preparación antígena del mismo, sus usos y procedimientos de preparación.
UY29428A1 (es) Fformulaciones de vacuna contra la gripe, sus usos en medicina y procedimientos de preparación
TH72570B (th) อิมัลชันของน้ำมันในน้ำชนิดผ่านการไมโครฟลูอิดไดซ์ และองค์ประกอบของวัคซีน
UY31024A1 (es) Vacuna
WO2005072679A3 (es) Formulación adyuvante conteniendo una emulsión oleosa con aceite de jojoba

Legal Events

Date Code Title Description
FC Refusal