AR052488A1 - Derivados de 2-quinolonas como inhibidores de fosfodiesterasas - Google Patents

Derivados de 2-quinolonas como inhibidores de fosfodiesterasas

Info

Publication number
AR052488A1
AR052488A1 ARP060100661A ARP060100661A AR052488A1 AR 052488 A1 AR052488 A1 AR 052488A1 AR P060100661 A ARP060100661 A AR P060100661A AR P060100661 A ARP060100661 A AR P060100661A AR 052488 A1 AR052488 A1 AR 052488A1
Authority
AR
Argentina
Prior art keywords
phosphodesterases
quinolones
inhibitors
derivatives
compound
Prior art date
Application number
ARP060100661A
Other languages
English (en)
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of AR052488A1 publication Critical patent/AR052488A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Abstract

Reivindicacion 1: Un compuesto de formula (1) o un solvato farmacéuticamente aceptable del mismo.
ARP060100661A 2005-02-25 2006-02-23 Derivados de 2-quinolonas como inhibidores de fosfodiesterasas AR052488A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0503955.7A GB0503955D0 (en) 2005-02-25 2005-02-25 Novel compounds

Publications (1)

Publication Number Publication Date
AR052488A1 true AR052488A1 (es) 2007-03-21

Family

ID=34430239

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP060100661A AR052488A1 (es) 2005-02-25 2006-02-23 Derivados de 2-quinolonas como inhibidores de fosfodiesterasas

Country Status (5)

Country Link
AR (1) AR052488A1 (es)
GB (1) GB0503955D0 (es)
PE (1) PE20061229A1 (es)
TW (1) TW200640870A (es)
WO (1) WO2006089689A1 (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2379076B1 (en) * 2008-12-23 2014-11-12 The Trustees of Columbia University in the City of New York Phosphodiesterase inhibitors and uses thereof
AR081026A1 (es) 2010-05-10 2012-05-30 Gilead Sciences Inc Analogos de quinolina y su uso en el tratamiento de enfermedades respiratorias
US8367829B2 (en) 2010-05-10 2013-02-05 Gilead Sciences, Inc. Bi-functional pyrazolopyridine compounds
CN103508950B (zh) * 2012-06-25 2016-04-20 南开大学 含亚胺结构的4-羟基-2-喹啉酮类化合物及其制备和应用
AP2015008663A0 (en) 2013-02-19 2015-08-31 Pfizer Azabenzimidazole compounds as inhibitors of PDE4 isozymes for the treatment of cns and other disorders
JP6713982B2 (ja) 2014-07-24 2020-06-24 ファイザー・インク ピラゾロピリミジン化合物
CU20170007A7 (es) 2014-08-06 2017-06-05 Pfizer Compuestos de imidazopiridazina

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2252501A1 (en) * 1996-05-20 1997-11-27 Darwin Discovery Limited Quinoline sulfonamides as tnf inhibitors and as pde-iv inhibitors
TWI328009B (en) * 2003-05-21 2010-08-01 Glaxo Group Ltd Quinoline derivatives as phosphodiesterase inhibitors

Also Published As

Publication number Publication date
GB0503955D0 (en) 2005-04-06
PE20061229A1 (es) 2006-12-04
WO2006089689A1 (en) 2006-08-31
TW200640870A (en) 2006-12-01

Similar Documents

Publication Publication Date Title
CY1118879T1 (el) Ενωσεις τριαζινης ως αναστολεις κινασης ρ13 και mtor
EA200801381A1 (ru) Производные пиримидина
NO20081554L (no) Isoindollmidforbindelser og sammensetninger omfattende samme, og anvendelse derav
AR106942A2 (es) Compuestos de isoindolina y composiciones farmacéuticas de los mismos
DE602006011752D1 (de) Als antikoagulationsmittel geeignete phenylglycinamid- und pyridylglycinamidderivate
ME01992B (me) Jedinjenje diarilhidantoina
RS52534B (en) MACROCYCLIC COMPOUNDS OF HINOXALINE AS HCV NS3 PROTEASE INHIBITORS
TW200728307A (en) Novel spirochromanone derivatives
EA200801428A1 (ru) Производные пиридиазинона для лечения опухолей
MY149512A (en) Pyrazolylaminopyridine derivatives useful as kinase inhibitors
PT1940839E (pt) Inibidores de piridopirimidinona pi3k alfa
MX2009007077A (es) Analogos de ciclopamina.
CR20110684A (es) Derivados de imidazolidin-2-ona 1,3-disustituida como inhibidores de cyp17
EA200870117A1 (ru) Азаиндоловые ингибиторы аурора-киназ
HK1119699A1 (en) Pyridopyrimidinone inhibitors of pi3kalpha
ATE553106T1 (de) Heteroarylpyrrolopyridinone als kinaseinhibitoren
IN2012DN03085A (es)
RS50720B (sr) 3,11 b-cis-dihidrotetrabenazin za lečenje proliferativne bolesti ili inflamacije
SE0400284D0 (sv) Novel compounds
AR062211A1 (es) Derivados de 6-carboxi-normorfinano. composiciones farmaceuticas
UY30310A1 (es) Derivados 2-azetidinona, sales, solvatos, composiciones farmacéuticas conteniéndolos, procesos de preparacion y aplicaciones
ECSP088677A (es) Piperazinas y piperidinas como potenciadores 157 del mglur5
EA200801199A1 (ru) Ингибиторы киназы
UY28821A1 (es) Hidrocloruro de (4-(5-aminometil-2-fluoro-fenil)-piperidin-1-il)-(4-bromo-3-metil-5-propoxi-tiofen-2-il)-metanona como un inhibidor de la triptasa de mastocitos.
EA200801366A1 (ru) Производные 3,6-дигидро-2-оксо-6н-1,3,4-тиадиазина

Legal Events

Date Code Title Description
FA Abandonment or withdrawal