AR040545A1 - Cefalosporinas - Google Patents
CefalosporinasInfo
- Publication number
- AR040545A1 AR040545A1 AR20030102508A ARP030102508A AR040545A1 AR 040545 A1 AR040545 A1 AR 040545A1 AR 20030102508 A AR20030102508 A AR 20030102508A AR P030102508 A ARP030102508 A AR P030102508A AR 040545 A1 AR040545 A1 AR 040545A1
- Authority
- AR
- Argentina
- Prior art keywords
- carbon atoms
- alkyl
- carbonyl
- hydrogen
- formula
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
- C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
- C07D501/38—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof
- C07D501/46—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof with the 7-amino radical acylated by carboxylic acids containing hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
- A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
- A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
- A61K31/546—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine containing further heterocyclic rings, e.g. cephalothin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
- C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
- C07D501/38—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Oncology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cephalosporin Compounds (AREA)
Abstract
Un compuesto de la fórmula (1): o de la fórmula (2). Reivindicación 1: Un compuesto de la fórmula (1): o de la fórmula (2): en donde: W es CH ó N, R1 es hidroxilo, alcoxilo (de 1 a 6 átomos de carbono), haloalcoxilo (de 1 a 6 átomos de carbono), hidroxicarbonilalcoxilo (de 1 a 6 átomos de carbono), o alcoxilo (de 1 a 6 átomos de carbono)-carbonilalcoxilo (de 1 a 6 átomos de carbono), R2 es hidrógeno o una fracción de éster, R3 es hidrógeno, alquilo (de 1 a 6 átomos de carbono), alquenilo (de 2 a 6 átomos de carbono), o cicloalquilo (de 3 a 8 átomos de carbono), R4 es hidrógeno o alquilo (de 1 a 6 átomos de carbono), en las fórmulas (1) y (2) la parte cíclica A es ciclohexilo o fenilo, R5 y R6, independientemente uno del otro, son hidrógeno; alquilo (de 1 a 6 átomos de carbono); alquenilo (de 2 a 6 átomos de carbono); arilcarbonilo (de 6 a 18 átomos de carbono); alquilo (de 1 a 6 átomos de carbono)-carbonilo; ariloxilo (de 6 a 18 átomos de carbono)-alquilo (de 1 a 4 átomos de carbono)-carbonilo; alquilo (de 1 a 6 átomos de carbono)-carbonilarilo (de 6 a 18 átomos de carbono)-carbonilo; heterociclilalquilo (de 1 a 6 átomos de carbono)-carbonilo, en donde heterociclilo comprende 5 ó 6 miembros del anillo y de 1 a 4 heteroátomos seleccionados a partir de N, O, ó S; alquilo (de 1 a 6 átomos de carbono)-sulfonilo, o arilo (de 6 a 18 átomos de carbono)-sulfonilo, X es NH, O, S, ó N-R8, en donde R8 es alquilo (de 1 a 6 átomos de carbono), o cicloalquilo (de 3 a 8 átomos de carbono), Y es O ó S, y n y m, independientemente uno del otro, son 0 ó 1.
Applications Claiming Priority (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB0216418A GB0216418D0 (en) | 2002-07-15 | 2002-07-15 | Organic compound |
GB0222177A GB0222177D0 (en) | 2002-09-24 | 2002-09-24 | Organic compounds |
GB0223975A GB0223975D0 (en) | 2002-10-15 | 2002-10-15 | Organic compounds |
GB0223977A GB0223977D0 (en) | 2002-10-15 | 2002-10-15 | Organic compounds |
GB0223974A GB0223974D0 (en) | 2002-10-15 | 2002-10-15 | Organic compounds |
GB0223976A GB0223976D0 (en) | 2002-10-15 | 2002-10-15 | Organic compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
AR040545A1 true AR040545A1 (es) | 2005-04-13 |
Family
ID=30119477
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AR20030102508A AR040545A1 (es) | 2002-07-15 | 2003-07-11 | Cefalosporinas |
Country Status (23)
Country | Link |
---|---|
US (1) | US7485632B2 (es) |
EP (1) | EP1529050B1 (es) |
JP (1) | JP2005536499A (es) |
KR (1) | KR20050037553A (es) |
CN (1) | CN1678616A (es) |
AR (1) | AR040545A1 (es) |
AT (1) | ATE327239T1 (es) |
AU (1) | AU2003250056A1 (es) |
BR (1) | BR0312698A (es) |
CA (1) | CA2492373A1 (es) |
CO (1) | CO5680481A2 (es) |
DE (1) | DE60305506T2 (es) |
EC (1) | ECSP055538A (es) |
ES (1) | ES2268429T3 (es) |
HK (1) | HK1077299A1 (es) |
IL (1) | IL166120A0 (es) |
MX (1) | MXPA05000664A (es) |
NO (1) | NO20050781L (es) |
PE (1) | PE20040657A1 (es) |
PL (1) | PL373104A1 (es) |
SI (1) | SI1529050T1 (es) |
TW (1) | TW200422044A (es) |
WO (1) | WO2004007505A1 (es) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2000189171A (ja) * | 1998-12-25 | 2000-07-11 | Banyu Pharmaceut Co Ltd | 新規なグアノシン三リン酸(gtp)結合タンパク質共役型のレセプタ―タンパク質 |
WO2015158863A1 (de) * | 2014-04-16 | 2015-10-22 | Sika Technology Ag | Schnell härtende migrationsfreie zusammensetzung auf basis von silangruppen-haltigen organischen polymeren |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5093989A (es) | 1973-10-25 | 1975-07-26 | ||
NZ308518A (en) * | 1995-05-11 | 2000-01-28 | Biochemie Gmbh | Antibacterial cephalosporins |
GB0301938D0 (en) * | 2003-01-28 | 2003-02-26 | Biochemie Gmbh | Organic compounds |
-
2003
- 2003-07-11 AR AR20030102508A patent/AR040545A1/es unknown
- 2003-07-11 PE PE2003000698A patent/PE20040657A1/es not_active Application Discontinuation
- 2003-07-14 TW TW092119157A patent/TW200422044A/zh unknown
- 2003-07-14 KR KR1020057000767A patent/KR20050037553A/ko not_active Application Discontinuation
- 2003-07-14 AU AU2003250056A patent/AU2003250056A1/en not_active Abandoned
- 2003-07-14 WO PCT/EP2003/007603 patent/WO2004007505A1/en active IP Right Grant
- 2003-07-14 BR BR0312698-6A patent/BR0312698A/pt not_active IP Right Cessation
- 2003-07-14 AT AT03763841T patent/ATE327239T1/de not_active IP Right Cessation
- 2003-07-14 DE DE60305506T patent/DE60305506T2/de not_active Withdrawn - After Issue
- 2003-07-14 CN CNA038199750A patent/CN1678616A/zh active Pending
- 2003-07-14 SI SI200330397T patent/SI1529050T1/sl unknown
- 2003-07-14 MX MXPA05000664A patent/MXPA05000664A/es unknown
- 2003-07-14 ES ES03763841T patent/ES2268429T3/es not_active Expired - Lifetime
- 2003-07-14 US US10/527,882 patent/US7485632B2/en not_active Expired - Fee Related
- 2003-07-14 CA CA002492373A patent/CA2492373A1/en not_active Abandoned
- 2003-07-14 PL PL03373104A patent/PL373104A1/xx not_active Application Discontinuation
- 2003-07-14 JP JP2004520619A patent/JP2005536499A/ja not_active Withdrawn
- 2003-07-14 EP EP03763841A patent/EP1529050B1/en not_active Expired - Lifetime
-
2005
- 2005-01-03 IL IL16612005A patent/IL166120A0/xx unknown
- 2005-01-13 EC EC2005005538A patent/ECSP055538A/es unknown
- 2005-01-17 CO CO05003029A patent/CO5680481A2/es not_active Application Discontinuation
- 2005-02-14 NO NO20050781A patent/NO20050781L/no not_active Application Discontinuation
- 2005-10-20 HK HK05109278A patent/HK1077299A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
JP2005536499A (ja) | 2005-12-02 |
WO2004007505A1 (en) | 2004-01-22 |
AU2003250056A1 (en) | 2004-02-02 |
MXPA05000664A (es) | 2005-04-25 |
IL166120A0 (en) | 2006-01-15 |
PE20040657A1 (es) | 2004-11-08 |
DE60305506D1 (de) | 2006-06-29 |
EP1529050B1 (en) | 2006-05-24 |
ES2268429T3 (es) | 2007-03-16 |
HK1077299A1 (en) | 2006-02-10 |
ATE327239T1 (de) | 2006-06-15 |
CO5680481A2 (es) | 2006-09-29 |
US20050234233A1 (en) | 2005-10-20 |
US7485632B2 (en) | 2009-02-03 |
TW200422044A (en) | 2004-11-01 |
CA2492373A1 (en) | 2004-01-22 |
EP1529050A1 (en) | 2005-05-11 |
DE60305506T2 (de) | 2007-04-19 |
PL373104A1 (en) | 2005-08-08 |
BR0312698A (pt) | 2005-05-03 |
KR20050037553A (ko) | 2005-04-22 |
SI1529050T1 (sl) | 2006-10-31 |
NO20050781L (no) | 2005-02-14 |
ECSP055538A (es) | 2005-03-10 |
CN1678616A (zh) | 2005-10-05 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FB | Suspension of granting procedure |