AR037046A1 - Un procedimiento para la preparacion de tetralona racemica opticamente pura o enriquecida - Google Patents

Un procedimiento para la preparacion de tetralona racemica opticamente pura o enriquecida

Info

Publication number
AR037046A1
AR037046A1 ARP020104076A ARP020104076A AR037046A1 AR 037046 A1 AR037046 A1 AR 037046A1 AR P020104076 A ARP020104076 A AR P020104076A AR P020104076 A ARP020104076 A AR P020104076A AR 037046 A1 AR037046 A1 AR 037046A1
Authority
AR
Argentina
Prior art keywords
tetralone
optically pure
procedure
preparation
racemic tetralone
Prior art date
Application number
ARP020104076A
Other languages
English (en)
Inventor
Luarent Berger
Raphael Duval
Philippe Taillasson
Ingo Weber
Alexander Wick
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of AR037046A1 publication Critical patent/AR037046A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/78—Separation; Purification; Stabilisation; Use of additives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/78—Separation; Purification; Stabilisation; Use of additives
    • C07C45/79—Separation; Purification; Stabilisation; Use of additives by solid-liquid treatment; by chemisorption

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Reivindicación 1:Un procedimiento para resolver cromatográficamente tetralona quiral sustancial y enantioméricamente pura a partir de una mezcla de dos enantiómeros de tetralona que comprende la provisión de una fase móvil líquida que comprende al menos un solvente; la provisión de una fase quiral estacionaria que comprende un portador inorgánico que tiene un complejo metálico-orgánico ópticamente puro; y, la separación cromatográfica de la mezcla para obtener al menos una tetralona sustancial y enantioméricamente pura.
ARP020104076A 2001-10-31 2002-10-28 Un procedimiento para la preparacion de tetralona racemica opticamente pura o enriquecida AR037046A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US33542901P 2001-10-31 2001-10-31

Publications (1)

Publication Number Publication Date
AR037046A1 true AR037046A1 (es) 2004-10-20

Family

ID=23311732

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP020104076A AR037046A1 (es) 2001-10-31 2002-10-28 Un procedimiento para la preparacion de tetralona racemica opticamente pura o enriquecida

Country Status (22)

Country Link
US (1) US6683220B2 (es)
EP (1) EP1444188A1 (es)
JP (1) JP2005507935A (es)
KR (1) KR20040070345A (es)
CN (1) CN1578756A (es)
AR (1) AR037046A1 (es)
BR (1) BR0213787A (es)
CA (1) CA2464916A1 (es)
EG (1) EG23132A (es)
HN (1) HN2002000308A (es)
IL (1) IL161256A0 (es)
MX (1) MXPA04003289A (es)
MY (1) MY133291A (es)
PA (1) PA8557601A1 (es)
PL (1) PL369722A1 (es)
RS (1) RS37204A (es)
RU (1) RU2004116325A (es)
SV (1) SV2003001293A (es)
TN (1) TNSN02087A1 (es)
TW (1) TWI221468B (es)
WO (1) WO2003037840A1 (es)
ZA (1) ZA200402652B (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004092110A2 (en) * 2003-04-14 2004-10-28 Teva Pharmaceutical Industries Ltd. Hydrogenation of imine intermediates of sertraline with catalysts
US20060128955A1 (en) * 2003-05-09 2006-06-15 Vela Pharmaceuticals, Inc. Method of isolating (R)-tofisopam
KR100739537B1 (ko) 2004-01-07 2007-07-13 주식회사 카이로라이트 카이랄 무기-유기 혼성 다공성 물질 및 이의 제조 방법
US7345201B2 (en) * 2005-02-23 2008-03-18 Teva Pharmaceutical Industries, Ltd. Processes for preparing sertraline
US7413660B2 (en) * 2005-09-30 2008-08-19 3M Innovative Properties Company Single pass method and apparatus for separating a target molecule from a liquid mixture
KR100925316B1 (ko) * 2007-12-20 2009-11-04 노운섭 접합필름인쇄용 잉크조성물

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992015617A1 (en) * 1991-02-28 1992-09-17 Daicel Chemical Industries, Ltd. Separating agent
US5403898A (en) * 1992-05-04 1995-04-04 Brigham Young University Single arm attached cyclodextrin polysiloxanes and use thereof as chiral stationary phases in chromatographic separation of enantiomers
JP2686366B2 (ja) * 1993-11-30 1997-12-08 ファイザー・インコーポレーテッド キラルテトラロンの製造方法
CA2342201C (en) * 1998-05-01 2005-08-09 Pfizer Products Inc. Process for the production of enantiomerically pure or optically enriched sertraline-tetralone using continuous chromatography
FR2785196B1 (fr) * 1998-10-29 2000-12-15 Inst Francais Du Petrole Procede et dispositif de separation avec des zones chromatographiques a longueur variable

Also Published As

Publication number Publication date
KR20040070345A (ko) 2004-08-07
WO2003037840A8 (en) 2004-07-22
MXPA04003289A (es) 2004-07-23
BR0213787A (pt) 2004-11-09
PL369722A1 (en) 2005-05-02
EP1444188A1 (en) 2004-08-11
HN2002000308A (es) 2003-01-18
TWI221468B (en) 2004-10-01
EG23132A (en) 2004-04-28
WO2003037840A1 (en) 2003-05-08
PA8557601A1 (es) 2004-02-07
CN1578756A (zh) 2005-02-09
RS37204A (en) 2006-12-15
US20030105364A1 (en) 2003-06-05
TNSN02087A1 (fr) 2004-03-05
IL161256A0 (en) 2004-09-27
MY133291A (en) 2007-11-30
US6683220B2 (en) 2004-01-27
SV2003001293A (es) 2003-04-03
CA2464916A1 (en) 2003-05-08
RU2004116325A (ru) 2005-11-10
JP2005507935A (ja) 2005-03-24
ZA200402652B (en) 2006-05-31

Similar Documents

Publication Publication Date Title
DK1073618T3 (da) Fremgangsmåde til fremstilling af enantiomerisk ren eller optisk beriget sertralin-tetralon under anvendelse af kontinuerlig kromatografi
BR0210817A (pt) Método para a preparação de escitalopram, e, intermediário
ES2141632A1 (es) Procedimiento para la obtencion de un enantiomero opticamente puro de formoterol.
EA199900561A1 (ru) Производные сульфонамида, способ их получения и их использование в качестве лекарственных средств
DK0552041T3 (da) Enzymatiske fremgangsmåder til spaltning af enantiomerblandinger af forbindelser, der er nyttige som mellemprodukter ved fr
EE03100B1 (et) Meetod taksoidide puhastamiseks
DK1133283T3 (da) Fremgangsmåde til fremstilling af lægemiddelpartikler
CO4940432A1 (es) (+)-norcisapride
AR037046A1 (es) Un procedimiento para la preparacion de tetralona racemica opticamente pura o enriquecida
ES2105510T3 (es) Resolucion enantiomerica de 4-(3,4-diclorofenil)-3,4-dihidro-1(2h)-naftalenona.
Pirkle et al. On the relevance of face-to-edge π-π interactions to chiral recognition
GB2427374A (en) Compositions and methods for separating enantiomers
Horeau et al. Secondary deuterium isotope effects in asymmetric syntheses and kinetic resolutions
Raja et al. Chiral separation of calcium channel antagonists by SFC and HPLC using different immobilized chiral stationary phases
BR9903274A (pt) Processo para isolar vitamina d3
Uray et al. Diphenylethanediamine derivatives as chiral selectors: III. Comparison of four new diastereomeric chiral stationary phases prepared by addition of mono-3, 5-dinitrobenzoyldiphenylethanediamine derivatives to optically pure epoxy silica
EA200000069A1 (ru) Способ получения 4-замещенных-1h-индол-3-глиоксамидов
IL140240A0 (en) Chiral stationary phases for enantiomer separation and their preparation
Brown et al. A new chiral acid for the resolution of racemic bases:(s)-(-)-(2-phenylcarbamoyloxy) propionic acid (carbamalactic acid)
Yi et al. Identifying lactone hydrolysis in pharmaceuticals. A tool for metabolite structural characterization
NO994928L (no) FremgangsmÕte ved fremstilling av enkelt-enantiomer narwedine
ES2099477T3 (es) Procedimiento para separar enantiomeros a partir de una mezcla racemica.
BR9908511A (pt) Processo para a preparação de um composto, e, composto
TR200103287T2 (tr) Dallanmış çözücülerle polimerler içeren sıvı fazların faz ayrılmasının hızlandırılması.
PT920447E (pt) Processo para a purificacao de ciclosporinas

Legal Events

Date Code Title Description
FG Grant, registration