AR027484A1 - Proteina de fusion util en el tratamiento o prevencion del herpes zoster y en la prevencion o tratamiento de infecciones de varicela, adn y arn quecodifican dicha proteina; vectores de expresion y microorganismos recombinantes que comprenden dicho adn o arn; composiciones de vacuna que incluyen dich - Google Patents
Proteina de fusion util en el tratamiento o prevencion del herpes zoster y en la prevencion o tratamiento de infecciones de varicela, adn y arn quecodifican dicha proteina; vectores de expresion y microorganismos recombinantes que comprenden dicho adn o arn; composiciones de vacuna que incluyen dichInfo
- Publication number
- AR027484A1 AR027484A1 ARP000100224A ARP000100224A AR027484A1 AR 027484 A1 AR027484 A1 AR 027484A1 AR P000100224 A ARP000100224 A AR P000100224A AR P000100224 A ARP000100224 A AR P000100224A AR 027484 A1 AR027484 A1 AR 027484A1
- Authority
- AR
- Argentina
- Prior art keywords
- rna
- dna
- treatment
- prevention
- protein
- Prior art date
Links
- 108090000623 proteins and genes Proteins 0.000 title abstract 5
- 102000004169 proteins and genes Human genes 0.000 title abstract 5
- 108020001507 fusion proteins Proteins 0.000 title abstract 2
- 208000015181 infectious disease Diseases 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title abstract 2
- 229960005486 vaccine Drugs 0.000 title abstract 2
- 230000002265 prevention Effects 0.000 title 2
- 101100331550 Antirrhinum majus DICH gene Proteins 0.000 title 1
- 208000007514 Herpes zoster Diseases 0.000 title 1
- XQFRJNBWHJMXHO-RRKCRQDMSA-N IDUR Chemical compound C1[C@H](O)[C@@H](CO)O[C@H]1N1C(=O)NC(=O)C(I)=C1 XQFRJNBWHJMXHO-RRKCRQDMSA-N 0.000 title 1
- 239000013604 expression vector Substances 0.000 title 1
- 244000005700 microbiome Species 0.000 title 1
- 241000701085 Human alphaherpesvirus 3 Species 0.000 abstract 3
- 239000012634 fragment Substances 0.000 abstract 2
- 102000037865 fusion proteins Human genes 0.000 abstract 1
- 239000013598 vector Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16711—Varicellovirus, e.g. human herpesvirus 3, Varicella Zoster, pseudorabies
- C12N2710/16722—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16711—Varicellovirus, e.g. human herpesvirus 3, Varicella Zoster, pseudorabies
- C12N2710/16734—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Virology (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Abstract
Una proteína de fusion que comprende (1) una proteína gE del virus de la varicela Zoster o un fragmento inmunologicamente activo de la misma fusionados a(2) una proteína diferente del virus de la Varicela Zoster o un fragmento inmunologicamente activ o de la misma. También se propone el ADN y/o ARN y vectoresrecombinantes que codifican dicha proteína y composiciones de vacuna formuladas con dichas proteínas de aplicacion para el tratamiento de pacientes afectados osusceptibles de ser afectados po r infecciones o recurrencias del virus de la varicela zoster.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9901254.4A GB9901254D0 (en) | 1999-01-20 | 1999-01-20 | Vaccines |
Publications (1)
Publication Number | Publication Date |
---|---|
AR027484A1 true AR027484A1 (es) | 2003-04-02 |
Family
ID=10846213
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP000100224A AR027484A1 (es) | 1999-01-20 | 2000-01-18 | Proteina de fusion util en el tratamiento o prevencion del herpes zoster y en la prevencion o tratamiento de infecciones de varicela, adn y arn quecodifican dicha proteina; vectores de expresion y microorganismos recombinantes que comprenden dicho adn o arn; composiciones de vacuna que incluyen dich |
Country Status (5)
Country | Link |
---|---|
AR (1) | AR027484A1 (es) |
AU (1) | AU2292600A (es) |
CO (1) | CO5241364A1 (es) |
GB (1) | GB9901254D0 (es) |
WO (1) | WO2000043527A1 (es) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB0504436D0 (en) * | 2005-03-03 | 2005-04-06 | Glaxosmithkline Biolog Sa | Vaccine |
AU2012213948B2 (en) * | 2005-03-03 | 2016-01-21 | Glaxosmithkline Biologicals S.A. | Vaccine |
RU2010105858A (ru) * | 2007-07-19 | 2011-08-27 | Новавакс, Инк. (Us) | Вирусоподобные частицы (vlp) вируса varicella zoster и антигены |
JP6099573B2 (ja) * | 2011-01-31 | 2017-03-22 | ザ トラスティーズ オブ ザ ユニバーシティ オブ ペンシルバニア | 新規なヘルペス抗原をコードする核酸分子、それを含むワクチン及びその使用方法 |
KR101723605B1 (ko) * | 2014-10-21 | 2017-04-07 | 진원생명과학 주식회사 | 대상포진 예방 및 치료용 dna 백신 조성물 및 이를 이용한 vzv 항원에 대한 t세포 활성화 방법 |
WO2018097642A1 (ko) * | 2016-11-25 | 2018-05-31 | 재단법인 목암생명과학연구소 | 바리셀라 조스터 바이러스 백신 |
KR102028463B1 (ko) * | 2016-11-25 | 2019-10-04 | 재단법인 목암생명과학연구소 | 바리셀라 조스터 바이러스 백신 |
CN112142828B (zh) * | 2019-06-28 | 2022-02-01 | 怡道生物科技(苏州)有限公司 | 一种gE基因及表达该基因的载体 |
WO2021115410A1 (zh) * | 2019-12-13 | 2021-06-17 | 南京远大赛威信生物医药有限公司 | 免疫刺激组合物及其用途 |
CN115819616A (zh) * | 2021-07-28 | 2023-03-21 | 江苏瑞科生物技术股份有限公司 | 一种基因重组vzv融合蛋白及其制备方法和应用 |
AU2022397292A1 (en) | 2021-11-24 | 2024-05-30 | Flagship Pioneering Innovations Vi, Llc | Varicella-zoster virus immunogen compositions and their uses |
CN114891830B (zh) * | 2022-04-02 | 2024-03-01 | 武汉博沃生物科技有限公司 | 基于水痘-带状疱疹病毒的重组表达载体、重组病毒及用途 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE69017769T2 (de) * | 1989-06-27 | 1995-07-13 | Smithkline Beecham Biologicals S.A., Rixensart | Verbindungen. |
GB9226768D0 (en) * | 1992-12-23 | 1993-02-17 | Smithkline Beecham Biolog | Vaccines |
GB9413751D0 (en) * | 1994-07-07 | 1994-08-24 | British Bio Technology | Immunodominant peptides |
ES2301175T3 (es) * | 1996-02-09 | 2008-06-16 | Smithkline Beecham Biologicals S.A. | Vacunas contra el producto del gen 63 del virus de la varicela zoster. |
-
1999
- 1999-01-20 GB GBGB9901254.4A patent/GB9901254D0/en not_active Ceased
-
2000
- 2000-01-17 WO PCT/EP2000/000352 patent/WO2000043527A1/en active Search and Examination
- 2000-01-17 AU AU22926/00A patent/AU2292600A/en not_active Abandoned
- 2000-01-18 AR ARP000100224A patent/AR027484A1/es unknown
- 2000-01-20 CO CO00002923A patent/CO5241364A1/es not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
AU2292600A (en) | 2000-08-07 |
CO5241364A1 (es) | 2003-01-31 |
GB9901254D0 (en) | 1999-03-10 |
WO2000043527A1 (en) | 2000-07-27 |
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