WO2001055353A3 - Recombinant attenuation of prrsv - Google Patents
Recombinant attenuation of prrsv Download PDFInfo
- Publication number
- WO2001055353A3 WO2001055353A3 PCT/EP2001/000865 EP0100865W WO0155353A3 WO 2001055353 A3 WO2001055353 A3 WO 2001055353A3 EP 0100865 W EP0100865 W EP 0100865W WO 0155353 A3 WO0155353 A3 WO 0155353A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- orf
- viruses
- prrsv
- prrs
- attenuation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
- C12N7/04—Inactivation or attenuation; Producing viral sub-units
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
- A61K2039/522—Bacterial cells; Fungal cells; Protozoal cells avirulent or attenuated
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5254—Virus avirulent or attenuated
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/10011—Arteriviridae
- C12N2770/10022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/10011—Arteriviridae
- C12N2770/10061—Methods of inactivation or attenuation
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Virology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Gastroenterology & Hepatology (AREA)
- Molecular Biology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biophysics (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Surface Acoustic Wave Elements And Circuit Networks Thereof (AREA)
Abstract
Priority Applications (9)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
BR0107827-5A BR0107827A (en) | 2000-01-26 | 2001-01-26 | Recombinant attenuation of prrsv |
AU2001228502A AU2001228502A1 (en) | 2000-01-26 | 2001-01-26 | Recombinant attenuation of prrsv |
MXPA02007198A MXPA02007198A (en) | 2000-01-26 | 2001-01-26 | Recombinant attenuation of prrsv. |
EP01946891A EP1254213A2 (en) | 2000-01-26 | 2001-01-26 | Recombinant attenuation of prrsv |
HU0204176A HUP0204176A3 (en) | 2000-01-26 | 2001-01-26 | Recombinant attenuation of prrsv |
SK1093-2002A SK10932002A3 (en) | 2000-01-26 | 2001-01-26 | Live attenuated prrs virus containing orf 1a, 1b and 2, a nucleotide sequence coding said virus, method of generating such virus, pharmaceutical composition comprising same and use thereof |
EA200200743A EA200200743A1 (en) | 2000-01-26 | 2001-01-26 | RECOMBINANT REDUCTION OF THE VIRUS REPRODUCTIVE AND RESPIRATORY SYNDROME OF PIGS (PRRSV) |
CA002396454A CA2396454A1 (en) | 2000-01-26 | 2001-01-26 | Recombinant attenuation of prrsv |
JP2001554384A JP2003520601A (en) | 2000-01-26 | 2001-01-26 | Recombinant attenuation of PRRSV |
Applications Claiming Priority (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE2000103372 DE10003372A1 (en) | 2000-01-26 | 2000-01-26 | Novel live porcine reproductive and respiratory syndrome virus attenuated by mutations in specific site of viral protein coded by specified open reading frames, useful for prophylaxis/treatment of viral infections |
DE10003371.7 | 2000-01-26 | ||
DE10003372.5 | 2000-01-26 | ||
DE2000103373 DE10003373A1 (en) | 2000-01-26 | 2000-01-26 | Novel live porcine reproductive and respiratory syndrome virus attenuated by mutations in specific site of viral protein coded by specified open reading frames, useful for prophylaxis/treatment of viral infections |
DE2000103371 DE10003371A1 (en) | 2000-01-26 | 2000-01-26 | Novel live porcine reproductive and respiratory syndrome virus attenuated by mutations in specific site of viral protein coded by specified open reading frames, useful for prophylaxis/treatment of viral infections |
DE10003373.3 | 2000-01-26 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2001055353A2 WO2001055353A2 (en) | 2001-08-02 |
WO2001055353A3 true WO2001055353A3 (en) | 2001-12-27 |
Family
ID=27213605
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/EP2001/000865 WO2001055353A2 (en) | 2000-01-26 | 2001-01-26 | Recombinant attenuation of prrsv |
Country Status (15)
Country | Link |
---|---|
EP (1) | EP1254213A2 (en) |
JP (1) | JP2003520601A (en) |
KR (1) | KR20030032910A (en) |
CN (1) | CN1406277A (en) |
AR (1) | AR027291A1 (en) |
AU (1) | AU2001228502A1 (en) |
BR (1) | BR0107827A (en) |
CA (1) | CA2396454A1 (en) |
CZ (1) | CZ20022554A3 (en) |
EA (1) | EA200200743A1 (en) |
HU (1) | HUP0204176A3 (en) |
MX (1) | MXPA02007198A (en) |
PL (1) | PL356274A1 (en) |
SK (1) | SK10932002A3 (en) |
WO (1) | WO2001055353A2 (en) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BR0207988A (en) * | 2001-03-09 | 2004-10-26 | Boehringer Ingelheim Vetmed | Live attenuated strains of prrs virus |
US6841364B2 (en) * | 2002-01-22 | 2005-01-11 | Protatek International, Inc. | Infectious cDNA clones of porcine reproductive and respiratory syndrome virus and expression vectors thereof |
AU2004223808B2 (en) | 2003-03-27 | 2009-03-26 | Ottawa Health Research Institute | Mutant vesicular stomatitis viruses and use thereof |
KR20100090311A (en) * | 2005-02-25 | 2010-08-13 | 화이자 프로덕츠 인크. | N protein mutants of porcine reproductive and respiratory syndrome virus |
CN100439494C (en) * | 2007-03-14 | 2008-12-03 | 中国动物疫病预防控制中心 | Swine reproduction and respiration syndrome vaccine and its prepn process and application |
US7666585B2 (en) | 2007-06-15 | 2010-02-23 | Protatek International, Inc. | Construction of chimera PRRSV, compositions and vaccine preparations |
CN101307305B (en) * | 2008-04-30 | 2010-06-16 | 中国动物疫病预防控制中心 | Low virulent strain of porcine reproductive and respiratory syndrome virus, immunogenicity immunogenicity material and vaccine |
UA108902C2 (en) * | 2010-11-10 | 2015-06-25 | NORTH AMERICAN REPRODUCTIVE AND RESPIRATORY PIG SYNDROME (PRRS) VIRUS | |
KR20170002393A (en) * | 2014-03-21 | 2017-01-06 | 엔유테크 벤처스 | A non-naturally occuring porcine reproductive and respiratory syndrome virus (prrsv) and methods of using |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1996004010A1 (en) * | 1994-08-05 | 1996-02-15 | Regents Of The University Of Minnesota | Vr-2332 viral nucleotide sequence and methods of use |
WO1996040932A1 (en) * | 1995-06-07 | 1996-12-19 | Paul Prem S | Vaccine for porcine reproductive and respiratory syndrome virus |
EP0839912A1 (en) * | 1996-10-30 | 1998-05-06 | Instituut Voor Dierhouderij En Diergezondheid (Id-Dlo) | Infectious clones of RNA viruses and vaccines and diagnostic assays derived thereof |
-
2001
- 2001-01-26 EA EA200200743A patent/EA200200743A1/en unknown
- 2001-01-26 HU HU0204176A patent/HUP0204176A3/en unknown
- 2001-01-26 AU AU2001228502A patent/AU2001228502A1/en not_active Abandoned
- 2001-01-26 CA CA002396454A patent/CA2396454A1/en not_active Abandoned
- 2001-01-26 EP EP01946891A patent/EP1254213A2/en not_active Withdrawn
- 2001-01-26 PL PL01356274A patent/PL356274A1/en not_active Application Discontinuation
- 2001-01-26 JP JP2001554384A patent/JP2003520601A/en active Pending
- 2001-01-26 CZ CZ20022554A patent/CZ20022554A3/en unknown
- 2001-01-26 BR BR0107827-5A patent/BR0107827A/en active Pending
- 2001-01-26 CN CN01804245A patent/CN1406277A/en active Pending
- 2001-01-26 KR KR1020027008256A patent/KR20030032910A/en not_active Application Discontinuation
- 2001-01-26 SK SK1093-2002A patent/SK10932002A3/en unknown
- 2001-01-26 MX MXPA02007198A patent/MXPA02007198A/en unknown
- 2001-01-26 AR ARP010100333A patent/AR027291A1/en not_active Suspension/Interruption
- 2001-01-26 WO PCT/EP2001/000865 patent/WO2001055353A2/en not_active Application Discontinuation
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1996004010A1 (en) * | 1994-08-05 | 1996-02-15 | Regents Of The University Of Minnesota | Vr-2332 viral nucleotide sequence and methods of use |
WO1996040932A1 (en) * | 1995-06-07 | 1996-12-19 | Paul Prem S | Vaccine for porcine reproductive and respiratory syndrome virus |
EP0839912A1 (en) * | 1996-10-30 | 1998-05-06 | Instituut Voor Dierhouderij En Diergezondheid (Id-Dlo) | Infectious clones of RNA viruses and vaccines and diagnostic assays derived thereof |
Non-Patent Citations (4)
Title |
---|
ALLENDE R. ET AL.: "Mutations in the genome of porcine reproductive and respiratory syndrome virus responsible for the attenuation phenotype", ARCHIVES OF VIROLOGY, vol. 145, no. 6, June 2000 (2000-06-01), VIENNA AT, pages 1149 - 1161, XP000926571 * |
SNIJDER E J ET AL: "THE MOLECULAR BIOLOGY OF ARTERIVIRUSES", JOURNAL OF GENERAL VIROLOGY READING, vol. 79, 1998, GB, pages 961 - 979, XP000791110, ISSN: 0022-1317 * |
YANG S X ET AL: "Comparative sequence analysis of open reading frames 2 to 7 of the modified live vaccine virus and other North American isolates of the porcine reproductive and respiratory syndrome virus.", ARCHIVES OF VIROLOGY, vol. 143, no. 3, 1998, pages 601 - 612, XP000926565, ISSN: 0304-8608 * |
YUAN SHISHAN ET AL: "Complete genome comparison of porcine reproductive and respiratory syndrome virus parental and attenuated strains.", VIRUS RESEARCH, vol. 74, no. 1-2, April 2001 (2001-04-01), pages 99 - 110, XP000926563, ISSN: 0168-1702 * |
Also Published As
Publication number | Publication date |
---|---|
EA200200743A1 (en) | 2002-12-26 |
CZ20022554A3 (en) | 2002-10-16 |
AR027291A1 (en) | 2003-03-19 |
HUP0204176A3 (en) | 2003-12-29 |
AU2001228502A1 (en) | 2001-08-07 |
HUP0204176A2 (en) | 2003-04-28 |
CN1406277A (en) | 2003-03-26 |
CA2396454A1 (en) | 2001-08-02 |
EP1254213A2 (en) | 2002-11-06 |
MXPA02007198A (en) | 2002-12-09 |
KR20030032910A (en) | 2003-04-26 |
JP2003520601A (en) | 2003-07-08 |
WO2001055353A2 (en) | 2001-08-02 |
PL356274A1 (en) | 2004-06-28 |
BR0107827A (en) | 2002-11-05 |
SK10932002A3 (en) | 2002-11-06 |
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