AR021663A1 - Clatratos de dehidroepiandrosterona y composiciones farmaceuticas correspondientes - Google Patents

Clatratos de dehidroepiandrosterona y composiciones farmaceuticas correspondientes

Info

Publication number
AR021663A1
AR021663A1 ARP990106362A ARP990106362A AR021663A1 AR 021663 A1 AR021663 A1 AR 021663A1 AR P990106362 A ARP990106362 A AR P990106362A AR P990106362 A ARP990106362 A AR P990106362A AR 021663 A1 AR021663 A1 AR 021663A1
Authority
AR
Argentina
Prior art keywords
dehydroepiandrosterone
clarrates
corresponding pharmaceutical
pharmaceutical compositions
insufficiencies
Prior art date
Application number
ARP990106362A
Other languages
English (en)
Original Assignee
Euphar Group Srl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Euphar Group Srl filed Critical Euphar Group Srl
Publication of AR021663A1 publication Critical patent/AR021663A1/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/40Cyclodextrins; Derivatives thereof
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6949Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
    • A61K47/6951Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/24Drugs for disorders of the endocrine system of the sex hormones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/24Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/26Androgens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/38Drugs for disorders of the endocrine system of the suprarenal hormones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/38Drugs for disorders of the endocrine system of the suprarenal hormones
    • A61P5/40Mineralocorticosteroids, e.g. aldosterone; Drugs increasing or potentiating the activity of mineralocorticosteroids

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Reproductive Health (AREA)
  • Nanotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Ophthalmology & Optometry (AREA)
  • Biotechnology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Gynecology & Obstetrics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

La presente invencion se refiere a clatratos de dehidroepiandrosterona, posiblemente en la forma de sulfatos, en una matriz que consiste de unaciclodextrina y opcionalmente comprende un agente de co-solubilizacion, y la correspondiente composicion farmacéutica adecuada para terapias de sustitucionpara el tratamiento de insuficiencias adrenocorticales.
ARP990106362A 1998-12-18 1999-12-14 Clatratos de dehidroepiandrosterona y composiciones farmaceuticas correspondientes AR021663A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT1998MI002745A IT1304190B1 (it) 1998-12-18 1998-12-18 Clatrati di deidroepiandrosterone e relative composizionifarmaceutiche

Publications (1)

Publication Number Publication Date
AR021663A1 true AR021663A1 (es) 2002-07-31

Family

ID=11381280

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP990106362A AR021663A1 (es) 1998-12-18 1999-12-14 Clatratos de dehidroepiandrosterona y composiciones farmaceuticas correspondientes

Country Status (24)

Country Link
EP (1) EP1140110B1 (es)
JP (1) JP2002532565A (es)
KR (1) KR100693514B1 (es)
CN (1) CN1198620C (es)
AR (1) AR021663A1 (es)
AT (1) ATE243517T1 (es)
AU (1) AU759979B2 (es)
BR (1) BR9916288A (es)
CA (1) CA2355148A1 (es)
CO (1) CO5231137A1 (es)
DE (1) DE69909128T2 (es)
DK (1) DK1140110T3 (es)
EA (1) EA003304B1 (es)
ES (1) ES2203232T3 (es)
HU (1) HU225414B1 (es)
IL (2) IL143776A0 (es)
IT (1) IT1304190B1 (es)
NZ (1) NZ512795A (es)
PE (1) PE20001379A1 (es)
PT (1) PT1140110E (es)
TR (1) TR200101766T2 (es)
TW (1) TWI225791B (es)
WO (1) WO2000037109A2 (es)
ZA (1) ZA200105223B (es)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2815860B1 (fr) * 2000-10-26 2003-12-12 Oreal Composition, notamment cosmetique, comprenant la dhea et/ou precurseur ou derive de celle-ci et au moins un agent myorelaxant
EP1285927A3 (de) * 2001-08-16 2005-06-29 Schering Aktiengesellschaft Verwendung von Glucocorticoid-Rezeptorantagonisten zur Vorbeugung und Behandlung von Erkrankungen des männlichen Reproduktionssystems
ITMI20021074A1 (it) * 2002-05-20 2003-11-20 Actimex S R L Composizione ternaria comprendente una sostanza attiva e processo di comacinazione per la sua preparazione
ITMI20022549A1 (it) * 2002-12-02 2004-06-03 Actimex S R L Composizione quaternaria comprendente come sostanza attiva la propolis.
CN1950110B (zh) * 2004-04-01 2012-11-21 列日大学 嘧啶-2,4,6-三酮的药物组合物
JPWO2006137433A1 (ja) * 2005-06-21 2009-01-22 わかもと製薬株式会社 レボカバスチンを可溶化させた水性薬剤
ITPD20050224A1 (it) * 2005-07-19 2007-01-20 Actimex Srl Composizioni contenenti micronutrienti aventi in particolare attivita' antiossidante e loro impiego
US8268806B2 (en) * 2007-08-10 2012-09-18 Endorecherche, Inc. Pharmaceutical compositions
EP2734193B1 (en) * 2011-07-19 2015-05-20 Pantarhei Bioscience B.V. Tablet containing dehydroepiandrosterone (dhea)
DE102012101680A1 (de) * 2012-02-29 2013-08-29 Aicuris Gmbh & Co. Kg Pharmazeutische Zubereitung enthaltend ein antiviral wirksames Dihydrochinazolinderivat
EP2986634B1 (en) * 2013-04-19 2019-11-20 University of Houston System Cocrystalline dhea formulations
ES2914305T3 (es) 2017-12-26 2022-06-09 Ind Tech Res Inst Composición para mejorar la solubilidad de sustancias poco solubles, uso de la misma y formulación compleja que contiene la misma
EP3666260A1 (en) 2018-12-13 2020-06-17 Laboratorios Leon Farma SA Ethinyl estradiol-beta-cyclodextrin complex and process for preparing thereof

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2647343B1 (fr) * 1989-05-24 1994-05-06 Rhone Poulenc Sante Nouvelle forme pharmaceutique poreuse et sa preparation
US4978532A (en) * 1989-08-11 1990-12-18 Pharmedic Co. Dosage form for administration of dehydroepiandrosterone
US5120720A (en) * 1990-09-20 1992-06-09 The United States Of America As Represented By The Secretary Of The Department Of Health & Human Services Preparation of lipophile:hydroxypropylcyclodextrin complexes by a method using co-solubilizers
WO1994004155A1 (en) * 1992-08-19 1994-03-03 Health Resource Institute, Ltd. Dehydroepiandrosterone therapy for the treatment of eye disorders
WO1995015746A1 (en) * 1993-12-10 1995-06-15 The School Of Pharmacy Liposome delivery systems
WO1997017992A1 (en) * 1995-11-13 1997-05-22 Supergen, Inc. Improved formulation for administration of steroid compounds

Also Published As

Publication number Publication date
ES2203232T3 (es) 2004-04-01
JP2002532565A (ja) 2002-10-02
CN1198620C (zh) 2005-04-27
IL143776A0 (en) 2002-04-21
PT1140110E (pt) 2003-11-28
BR9916288A (pt) 2001-10-16
DK1140110T3 (da) 2003-10-20
IL143776A (en) 2007-03-08
WO2000037109A3 (en) 2000-09-14
PE20001379A1 (es) 2000-11-25
NZ512795A (en) 2003-08-29
ATE243517T1 (de) 2003-07-15
CA2355148A1 (en) 2000-06-29
DE69909128D1 (de) 2003-07-31
WO2000037109A2 (en) 2000-06-29
HUP0104822A2 (hu) 2002-05-29
EA003304B1 (ru) 2003-04-24
ZA200105223B (en) 2002-09-25
CN1333686A (zh) 2002-01-30
AU759979B2 (en) 2003-05-01
AU1981000A (en) 2000-07-12
EP1140110A2 (en) 2001-10-10
HUP0104822A3 (en) 2002-08-28
CO5231137A1 (es) 2002-12-27
HU225414B1 (en) 2006-11-28
DE69909128T2 (de) 2004-05-06
KR100693514B1 (ko) 2007-03-14
IT1304190B1 (it) 2001-03-08
ITMI982745A1 (it) 2000-06-18
EA200100674A1 (ru) 2001-12-24
TWI225791B (en) 2005-01-01
EP1140110B1 (en) 2003-06-25
KR20010086109A (ko) 2001-09-07
TR200101766T2 (tr) 2001-12-21

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Legal Events

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