AR020013A1 - Procedimiento para el encapsulado de una masa de relleno sensible al cizallamiento dentro de una capsula - Google Patents

Procedimiento para el encapsulado de una masa de relleno sensible al cizallamiento dentro de una capsula

Info

Publication number
AR020013A1
AR020013A1 ARP990105797A ARP990105797A AR020013A1 AR 020013 A1 AR020013 A1 AR 020013A1 AR P990105797 A ARP990105797 A AR P990105797A AR P990105797 A ARP990105797 A AR P990105797A AR 020013 A1 AR020013 A1 AR 020013A1
Authority
AR
Argentina
Prior art keywords
capsule
active agent
present
capsules
filling mass
Prior art date
Application number
ARP990105797A
Other languages
English (en)
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of AR020013A1 publication Critical patent/AR020013A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/07—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4833—Encapsulating processes; Filling of capsules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/07—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use
    • A61J3/071—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use into the form of telescopically engaged two-piece capsules
    • A61J3/072—Sealing capsules, e.g. rendering them tamper-proof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/07—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use
    • A61J3/071—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use into the form of telescopically engaged two-piece capsules
    • A61J3/074—Filling capsules; Related operations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Basic Packing Technique (AREA)
  • Confectionery (AREA)

Abstract

La presente invencion se refiere a un procedimiento para el encapsulado de una masa de relleno sensible al cizallamiento en una cápsula , caracterizadoporque dicha masa de relleno se calienta y seguidamente se enfría inmediatamente antes delencapsul ado. La invencion se refiere también a las cápsulas quepueden obtenerse mediante dicho procedimiento. El procedimiento de acuerdo con la presente invencion permite la obtencion de cápsulas que presentan una alta yconstante velocidad dedisolucion. La cantidad de agente activo ingerido puede por lo tanto disminuirse dado que el propio agente activo se disuelverápidamente. Los costos totales del medicamento por lo tanto también disminuyen. La alta homogeneidad (y por lo tanto laalta y constante v elocidad dedisolucion) de las cápsulas elaboradas con el procedimiento de acuerdo con la presente invencion garantiza la disponibilidad y efecto terapéutico reproduciblesdel agente activo que está contenido en la misma.
ARP990105797A 1998-11-17 1999-11-15 Procedimiento para el encapsulado de una masa de relleno sensible al cizallamiento dentro de una capsula AR020013A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP98121831 1998-11-17

Publications (1)

Publication Number Publication Date
AR020013A1 true AR020013A1 (es) 2002-03-27

Family

ID=8232985

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP990105797A AR020013A1 (es) 1998-11-17 1999-11-15 Procedimiento para el encapsulado de una masa de relleno sensible al cizallamiento dentro de una capsula

Country Status (35)

Country Link
US (1) US6352717B2 (es)
EP (1) EP1131037B1 (es)
JP (1) JP3623166B2 (es)
KR (1) KR100446118B1 (es)
CN (1) CN1172649C (es)
AR (1) AR020013A1 (es)
AT (1) ATE274895T1 (es)
AU (1) AU751446B2 (es)
BR (1) BR9915444B1 (es)
CA (1) CA2350943C (es)
CO (1) CO5150161A1 (es)
CZ (1) CZ299800B6 (es)
DE (1) DE69919889T2 (es)
DK (1) DK1131037T3 (es)
ES (1) ES2228141T3 (es)
HK (1) HK1042227B (es)
HR (1) HRP20010341A2 (es)
HU (1) HU226498B1 (es)
ID (1) ID30128A (es)
IL (2) IL143119A0 (es)
MA (1) MA26761A1 (es)
MY (1) MY120081A (es)
NO (1) NO20012384L (es)
NZ (1) NZ511663A (es)
PE (1) PE20001240A1 (es)
PL (1) PL190382B1 (es)
PT (1) PT1131037E (es)
RU (1) RU2219911C2 (es)
SI (1) SI1131037T1 (es)
TR (1) TR200101358T2 (es)
TW (1) TWI221767B (es)
UY (1) UY25803A1 (es)
WO (1) WO2000028942A1 (es)
YU (1) YU33001A (es)
ZA (1) ZA200103891B (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE292453T1 (de) * 1999-12-09 2005-04-15 Alza Corp Antivirale arznei
GB0027954D0 (en) * 2000-11-16 2001-01-03 Mw Encap Ltd Liquid filled capsules
ES2257998T3 (es) * 2000-12-20 2006-08-16 Swiss Caps Rechte Und Lizenzen Ag Procedimiento de troquelado rotatorio y cuña de llenado para fabricar capsulas, en especial capsulas blandas.
US7247010B2 (en) 2003-10-01 2007-07-24 Technophar Equipment & Service Limited Servo control for capsule making machine
GB0712972D0 (en) * 2007-07-04 2007-08-15 Glaxosmithkline Consumer Healt Formulation
EP2042180A1 (de) * 2007-09-28 2009-04-01 Swiss Caps Rechte und Lizenzen AG Phytosterol-haltige Präparate
CL2010000098A1 (es) * 2009-02-04 2011-01-21 Kalamazoo Holdings Inc Composicion antioxidante de extracto de hierbas comestibles, especies, frutas y/o verduras; metodos para estabilizar diferentes alimentos que comprende incorporar el antioxidante que se obtiene por extraccion con solvente polar hierbas comestibles, especias y/o frutas previamente desgrasadas por extraccion con solvente no polar.
EP2410970B1 (de) * 2009-03-26 2013-02-13 Swiss Caps Rechte und Lizenzen AG Verfahren und vorrichtung zur herstellung von weichkapseln
WO2013031972A1 (ja) * 2011-09-02 2013-03-07 株式会社三協 カプセル製造装置における内包液の供給用ポンプユニット 並びにこのポンプユニットを適用したカプセル剤の製造装置並びに製造方法 並びにこれによって製造されるカプセル剤
US10568811B2 (en) * 2016-02-22 2020-02-25 R.P. Scherer Technologies, Llc Multiple-fluid injection pump
CN109645530A (zh) * 2019-01-09 2019-04-19 安徽亳药千草国药股份有限公司 一种用于灌注富硒灵芝孢子油的软胶囊机

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2692404A (en) * 1949-12-07 1954-10-26 Gennell Capsulations Inc Method and apparatus for forming capsules
JPS56163656A (en) * 1980-05-22 1981-12-16 Nippon Elanco Device for filling hard gelatin capsule with viscous substance
US4656066A (en) * 1982-12-20 1987-04-07 Warner-Lambert Company Apparatus and method for sealing capsules
JPS59131355A (ja) * 1983-01-17 1984-07-28 森下仁丹株式会社 多重軟カプセルの製法
US4609403A (en) * 1984-03-12 1986-09-02 Warner-Lambert Company Foam soft gelatin capsules and their method of manufacture
DE8536337U1 (de) * 1985-12-23 1986-02-13 R.P. Scherer GmbH, 6930 Eberbach Füllkeil für eine Maschine zum Herstellen von Gelatinekapseln
FI80828C (fi) * 1988-04-08 1990-08-10 Piscina Oy Anordning foer vaermning av en vattenbaedd.
IL110752A (en) * 1993-09-13 2000-07-26 Abbott Lab Liquid semi-solid or solid pharmaceutical composition for an HIV protease inhibitor
SI0649651T1 (en) * 1993-09-28 2001-02-28 Scherer Gmbh R P Soft gelatin capsule manufacture
GB9403449D0 (en) * 1994-02-23 1994-04-13 Wellcome Found Therapeutic benzonitriles
KR960016371U (ko) * 1994-11-11 1996-06-17 김덕흥 소프트젤라틴 캡슐제조기의 젤라틴시트 냉각장치

Also Published As

Publication number Publication date
WO2000028942A1 (en) 2000-05-25
CN1326335A (zh) 2001-12-12
PE20001240A1 (es) 2000-11-14
ATE274895T1 (de) 2004-09-15
JP2002529200A (ja) 2002-09-10
CN1172649C (zh) 2004-10-27
BR9915444A (pt) 2001-08-07
NO20012384D0 (no) 2001-05-15
NZ511663A (en) 2003-08-29
AU751446B2 (en) 2002-08-15
RU2219911C2 (ru) 2003-12-27
KR100446118B1 (ko) 2004-08-30
IL143119A0 (en) 2002-04-21
KR20010075711A (ko) 2001-08-09
PL348350A1 (en) 2002-05-20
DE69919889T2 (de) 2005-09-15
YU33001A (sh) 2004-05-12
SI1131037T1 (en) 2004-12-31
HUP0104464A2 (hu) 2002-03-28
HK1042227A1 (en) 2002-08-09
DE69919889D1 (de) 2004-10-07
UY25803A1 (es) 2000-08-21
MA26761A1 (fr) 2004-12-20
US6352717B2 (en) 2002-03-05
TWI221767B (en) 2004-10-11
ZA200103891B (en) 2002-08-14
HK1042227B (zh) 2005-03-18
CO5150161A1 (es) 2002-04-29
HRP20010341A2 (en) 2002-06-30
DK1131037T3 (da) 2005-01-10
ID30128A (id) 2001-11-08
CA2350943A1 (en) 2000-05-25
PT1131037E (pt) 2004-12-31
IL143119A (en) 2007-05-15
HU226498B1 (en) 2009-03-02
ES2228141T3 (es) 2005-04-01
CZ299800B6 (cs) 2008-11-26
EP1131037A1 (en) 2001-09-12
BR9915444B1 (pt) 2013-10-22
TR200101358T2 (tr) 2001-12-21
JP3623166B2 (ja) 2005-02-23
US20020006417A1 (en) 2002-01-17
CZ20011644A3 (cs) 2001-08-15
MY120081A (en) 2005-08-30
HUP0104464A3 (en) 2006-06-28
PL190382B1 (pl) 2005-12-30
AU1775100A (en) 2000-06-05
CA2350943C (en) 2006-06-20
NO20012384L (no) 2001-05-15
EP1131037B1 (en) 2004-09-01

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