AR011577A1 - COMPOSITION FOR THE TRANSDERMIC ADMINISTRATION OF A STEROID DRUG AND TRANSDERMIC FORMULATION INCLUDING IT - Google Patents

COMPOSITION FOR THE TRANSDERMIC ADMINISTRATION OF A STEROID DRUG AND TRANSDERMIC FORMULATION INCLUDING IT

Info

Publication number
AR011577A1
AR011577A1 ARP980100352A ARP980100352A AR011577A1 AR 011577 A1 AR011577 A1 AR 011577A1 AR P980100352 A ARP980100352 A AR P980100352A AR P980100352 A ARP980100352 A AR P980100352A AR 011577 A1 AR011577 A1 AR 011577A1
Authority
AR
Argentina
Prior art keywords
transdermic
composition
drug
formulation including
administration
Prior art date
Application number
ARP980100352A
Other languages
Spanish (es)
Original Assignee
Lg Chemical Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lg Chemical Ltd filed Critical Lg Chemical Ltd
Publication of AR011577A1 publication Critical patent/AR011577A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
    • A61K31/569—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone substituted in position 17 alpha, e.g. ethisterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A61K9/7061—Polyacrylates

Abstract

Una composicion para la administracion transdérmica de una droga esteroide y formulacion transdérmica que la incluye, donde la composicion contiene unacantidad terapéuticamente efectiva de la droga; un promotor de absorcion que consisteesencialm ente de un dietilenglicol éter y un éster sorbitán; y unamatriz adhesiva farmacéuticamente aceptable, comprendiendo la formulacion una capa soporte protectora y una capa reservorio de droga, un lado de la cualestá laminado sobre lacapa protect ora y el otro lado está unido a una capa desprendible.A composition for transdermal administration of a steroid drug and a transdermal formulation including it, wherein the composition contains a therapeutically effective amount of the drug; an absorption promoter consisting essentially of a diethylene glycol ether and a sorbitan ester; and a pharmaceutically acceptable adhesive matrix, the formulation comprising a protective backing layer and a drug reservoir layer, one side of which is laminated onto the protective layer and the other side is bonded to a release layer.

ARP980100352A 1997-01-27 1998-01-27 COMPOSITION FOR THE TRANSDERMIC ADMINISTRATION OF A STEROID DRUG AND TRANSDERMIC FORMULATION INCLUDING IT AR011577A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR1019970002233A KR100215027B1 (en) 1997-01-27 1997-01-27 Composition for transdermal administration of steroid drugs and formulation containing same

Publications (1)

Publication Number Publication Date
AR011577A1 true AR011577A1 (en) 2000-08-30

Family

ID=19495561

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP980100352A AR011577A1 (en) 1997-01-27 1998-01-27 COMPOSITION FOR THE TRANSDERMIC ADMINISTRATION OF A STEROID DRUG AND TRANSDERMIC FORMULATION INCLUDING IT

Country Status (12)

Country Link
EP (1) EP1001812A1 (en)
JP (1) JP2000508349A (en)
KR (1) KR100215027B1 (en)
CN (1) CN1244806A (en)
AR (1) AR011577A1 (en)
AU (1) AU727811B2 (en)
BR (1) BR9807009A (en)
CA (1) CA2277970A1 (en)
ID (1) ID19755A (en)
RU (1) RU2176499C2 (en)
TW (1) TW537899B (en)
WO (1) WO1998032465A1 (en)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100294084B1 (en) * 1998-06-02 2001-09-22 성재갑 Composition for transdermal administration of non-steroid drugs and formulation containing same
WO2000040230A2 (en) * 1999-01-06 2000-07-13 Cedars-Sinai Medical Center Hormone replacement for breast cancer patients
KR100403051B1 (en) * 2000-07-25 2003-10-23 일양약품주식회사 Composition of matrix type patch for transdermal testosterone delivery and process for preparing the same
US6503894B1 (en) 2000-08-30 2003-01-07 Unimed Pharmaceuticals, Inc. Pharmaceutical composition and method for treating hypogonadism
DE10107663B4 (en) * 2001-02-19 2004-09-09 Lts Lohmann Therapie-Systeme Ag Testosterone-containing transdermal therapeutic system, process for its preparation and its use
FR2848112B1 (en) * 2002-12-10 2007-02-16 Besins Int Belgique PHARMACEUTICAL COMPOSITION FOR TRANSDERMAL OR TRANSMUCTIVE DELIVERY COMPRISING AT LEAST ONE PROGESTATIVE AND / OR AT LEAST ONE OESTROGEN, PREPARATION METHOD AND USES THEREOF
AU2003296810A1 (en) * 2002-12-10 2004-07-09 Besins International Belgique Pharmaceutical composition for transdermal or transmucous administration comprising a progestin or an estrogen, method for preparing same and uses thereof
FR2851470B1 (en) 2003-02-20 2007-11-16 Besins Int Belgique PHARMACEUTICAL COMPOSITION FOR TRANSDERMAL OR TRANSMUCTIVE DELIVERY
JP4422430B2 (en) * 2003-05-14 2010-02-24 帝國製薬株式会社 External patch containing estrogen and / or progestogen
GB0409498D0 (en) * 2004-04-28 2004-06-02 Hunter Fleming Ltd Transdermal steroid formulation
CN1313084C (en) * 2004-11-05 2007-05-02 郑会义 Percutaneous contraceptive drugs delivery system and method
DE102004059880A1 (en) * 2004-12-10 2006-06-14 Grünenthal GmbH Stable, hormone-containing (intermediate) product
JP2007045808A (en) * 2005-01-07 2007-02-22 Rohto Pharmaceut Co Ltd Skin care preparation
JP4969050B2 (en) * 2005-01-07 2012-07-04 ロート製薬株式会社 Topical skin preparation
US10080760B2 (en) 2009-10-27 2018-09-25 Besins Healthcare Luxembourg Sarl Transdermal pharmaceutical compositions comprising active agents
WO2013054809A1 (en) * 2011-10-14 2013-04-18 大正製薬株式会社 External preparation for skin
ES2885523T3 (en) 2011-11-23 2021-12-14 Therapeuticsmd Inc Natural combination hormone replacement formulations and therapies
US9301920B2 (en) 2012-06-18 2016-04-05 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
US20130338122A1 (en) 2012-06-18 2013-12-19 Therapeuticsmd, Inc. Transdermal hormone replacement therapies
US10806697B2 (en) 2012-12-21 2020-10-20 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10806740B2 (en) 2012-06-18 2020-10-20 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
US20150196640A1 (en) 2012-06-18 2015-07-16 Therapeuticsmd, Inc. Progesterone formulations having a desirable pk profile
US11246875B2 (en) 2012-12-21 2022-02-15 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10471072B2 (en) 2012-12-21 2019-11-12 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
JP5521025B2 (en) * 2012-12-21 2014-06-11 日本精化株式会社 Penetration enhancer
US9180091B2 (en) 2012-12-21 2015-11-10 Therapeuticsmd, Inc. Soluble estradiol capsule for vaginal insertion
US11266661B2 (en) 2012-12-21 2022-03-08 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10568891B2 (en) 2012-12-21 2020-02-25 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10537581B2 (en) 2012-12-21 2020-01-21 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
AU2015264003A1 (en) 2014-05-22 2016-11-17 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
US10328087B2 (en) 2015-07-23 2019-06-25 Therapeuticsmd, Inc. Formulations for solubilizing hormones
WO2017173071A1 (en) 2016-04-01 2017-10-05 Therapeuticsmd, Inc. Steroid hormone pharmaceutical composition
US10286077B2 (en) 2016-04-01 2019-05-14 Therapeuticsmd, Inc. Steroid hormone compositions in medium chain oils
KR101968873B1 (en) * 2018-09-21 2019-04-29 아이큐어 주식회사 Cosmetic composition comprising peptide derived from Botulinum toxin having improved cell penetrating ability

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4291015A (en) * 1979-08-14 1981-09-22 Key Pharmaceuticals, Inc. Polymeric diffusion matrix containing a vasodilator
JPH0744940B2 (en) * 1986-12-24 1995-05-17 ライオン株式会社 Base material for oral application
CH674618A5 (en) * 1987-04-02 1990-06-29 Ciba Geigy Ag
CA1333114C (en) * 1987-11-25 1994-11-15 Daniel C. Duan Pressure-sensitive adhesives and bioelectrodes constructed with the adhesive
US4906475A (en) * 1988-02-16 1990-03-06 Paco Pharmaceutical Services Estradiol transdermal delivery system
EP0370220B1 (en) * 1988-10-27 1996-01-10 Schering Aktiengesellschaft Gestode composition for transdermal application
US4973468A (en) * 1989-03-22 1990-11-27 Cygnus Research Corporation Skin permeation enhancer compositions
DE69010076T2 (en) * 1989-05-25 1994-12-08 Takeda Chemical Industries Ltd Transdermal therapeutic agent.
US5314685A (en) * 1992-05-11 1994-05-24 Agouron Pharmaceuticals, Inc. Anhydrous formulations for administering lipophilic agents

Also Published As

Publication number Publication date
ID19755A (en) 1998-07-30
CA2277970A1 (en) 1998-07-30
WO1998032465A1 (en) 1998-07-30
EP1001812A1 (en) 2000-05-24
AU5882098A (en) 1998-08-18
KR100215027B1 (en) 1999-08-16
KR19980066583A (en) 1998-10-15
AU727811B2 (en) 2000-12-21
TW537899B (en) 2003-06-21
BR9807009A (en) 2000-03-14
CN1244806A (en) 2000-02-16
JP2000508349A (en) 2000-07-04
RU2176499C2 (en) 2001-12-10

Similar Documents

Publication Publication Date Title
AR011577A1 (en) COMPOSITION FOR THE TRANSDERMIC ADMINISTRATION OF A STEROID DRUG AND TRANSDERMIC FORMULATION INCLUDING IT
US6277401B1 (en) Drug delivery device
ES2201434T3 (en) TRANSDERMAL THERAPEUTIC SYSTEM FOR THE ADMINISTRATION OF HORMONES.
AR043248A1 (en) UV-STABLE TRANSDERMAL THERAPEUTIC SYSTEM
DK193389A (en) TRANSDERMAL PHARMACEUTICAL SYSTEM
CA2453013A1 (en) Dermal, transdermal, mucosal or transmucosal ingredient delivery devices
KR940013496A (en) Transdermal administration system
AR040822A1 (en) AN ABSORBENT ARTICLE AND A METHOD FOR MAKING SUCH ABSORBENT ARTICLE
DK0697860T3 (en) Estradiol-containing transdermal therapeutic system
BR9815378A (en) A transdermal drug delivery system for an anti-inflammatory analgesic agent comprising diethylammonium salt diclofenac and the method of manufacturing it.
FI953533A0 (en) Transdermal therapeutic system with galantamine as effective agent
ES2139806T3 (en) PREPARATION OF PERCUTANEOUS ABSORPTION CONTAINING ISOSORBIDE DINITRATE.
KR910009249A (en) Percutaneous treatment system containing buprenorphine as active ingredient
DE59207727D1 (en) TRANSDERMAL THERAPEUTIC PLASTER
DE50111208D1 (en) MATRIX-CONTROLLED TRANSDERMALES SYSTEM FOR STABLE DERIVATIVES OF ACE-HEMMER
WO2002022109A3 (en) Patch comprising diclofenac
MXPA02009103A (en) Transdermal therapeutic system for the delivery of lerisetron.
FI900315A0 (en) SAETT ATT FRAMSTAELLA ETT YTLIGT THERAPEUTIC SYSTEM FLASHING INNEHAOLLER TILLVAEXT AV ELAKARTADE CELLER OCH TILLVAEXTFOERHINDRANDE ACTIVE CREAM, SPECIFICALLY 5-FLUORURACIL.
ES2057442T5 (en) DEVICE FOR THE SUPPLY OF ESTRADIOL BY TRANSDERMAL ROUTE AND MANUFACTURING PROCESS OF SUCH DEVICE.
ES2178076T3 (en) CYTOTOXIC T-CELL ACTIVATOR AND ITS EMPLOYMENT.
BRPI0011135B8 (en) transdermal therapeutic delivery system containing neuroleptic agent
ES2138945T3 (en) DRUG DRUG SUPPLY SYSTEM FOR THE TREATMENT OF CARDIAC DISEASES.

Legal Events

Date Code Title Description
FA Abandonment or withdrawal