AR010377A1 - Composiciones farmaceuticas para secar por congelacion que contienen compuestos de nucleosidos, procedimiento para su preparacion y uso de dichas composiciones para fabricar medicamentos. - Google Patents
Composiciones farmaceuticas para secar por congelacion que contienen compuestos de nucleosidos, procedimiento para su preparacion y uso de dichas composiciones para fabricar medicamentos.Info
- Publication number
- AR010377A1 AR010377A1 ARP970106075A ARP970106075A AR010377A1 AR 010377 A1 AR010377 A1 AR 010377A1 AR P970106075 A ARP970106075 A AR P970106075A AR P970106075 A ARP970106075 A AR P970106075A AR 010377 A1 AR010377 A1 AR 010377A1
- Authority
- AR
- Argentina
- Prior art keywords
- compositions
- procedure
- preparation
- independently represent
- pharmaceutical compositions
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7076—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
- A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
- A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Diabetes (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Organic Chemistry (AREA)
- Hematology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Dermatology (AREA)
- Inorganic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Saccharide Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
Composicion farmacéutica para secar por congelacion que comprende un nucleotido análogo, por ejemplo, un compuesto de la formula I en la cual R1 yR2 representan independientemente hidrogeno o halogeno, R3 y R4 representan independientement efenilo, o alquilo C1-C6 optativamente sustituido por uno omás sustituyentes seleccionados entre OR5, alquiltio C1-C6, NR6R7, fenilo, COOR8 y halogeno, R5, R6, R7 y R8 representan independientemente hidrogeno oalquilo C1-C6, y X representa unaporcion ácida, o una sal farmacéuticamente aceptable de la misma; manitol y un aditivo modificador que es cloruro de sodioo un poliol, que es adecuada para secar por congelacion; procedimiento para su preparacion y uso de dicha composicion paraf abricar un medicamento para eltratamiento de un transtorno de agregacion de plaquetas.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE9604795A SE9604795D0 (sv) | 1996-12-20 | 1996-12-20 | New pharmaceutical formulation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR010377A1 true AR010377A1 (es) | 2000-06-07 |
Family
ID=20405148
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP970106075A AR010377A1 (es) | 1996-12-20 | 1997-12-19 | Composiciones farmaceuticas para secar por congelacion que contienen compuestos de nucleosidos, procedimiento para su preparacion y uso de dichas composiciones para fabricar medicamentos. |
Country Status (36)
| Country | Link |
|---|---|
| US (1) | US6114313A (es) |
| EP (1) | EP1007094B1 (es) |
| JP (1) | JP4488538B2 (es) |
| KR (1) | KR100552880B1 (es) |
| CN (1) | CN1121875C (es) |
| AR (1) | AR010377A1 (es) |
| AT (1) | ATE221787T1 (es) |
| AU (1) | AU758857B2 (es) |
| BR (1) | BR9713974B1 (es) |
| CA (1) | CA2275153C (es) |
| CZ (1) | CZ300635B6 (es) |
| DE (1) | DE69714616T2 (es) |
| DK (1) | DK1007094T3 (es) |
| EE (1) | EE03857B1 (es) |
| ES (1) | ES2182133T3 (es) |
| FR (1) | FR15C0060I2 (es) |
| HK (1) | HK1026366A1 (es) |
| HU (1) | HU226616B1 (es) |
| ID (1) | ID21635A (es) |
| IL (1) | IL130449A0 (es) |
| IS (1) | IS1897B (es) |
| MY (1) | MY121982A (es) |
| NO (1) | NO327142B1 (es) |
| NZ (1) | NZ336027A (es) |
| PL (1) | PL190493B1 (es) |
| PT (1) | PT1007094E (es) |
| RU (1) | RU2205012C2 (es) |
| SA (1) | SA97180719B1 (es) |
| SE (1) | SE9604795D0 (es) |
| SI (1) | SI1007094T1 (es) |
| SK (1) | SK283137B6 (es) |
| TR (1) | TR199901412T2 (es) |
| TW (1) | TW522015B (es) |
| UA (1) | UA66779C2 (es) |
| WO (1) | WO1998028009A1 (es) |
| ZA (1) | ZA9711055B (es) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE9702680D0 (sv) * | 1997-07-11 | 1997-07-11 | Astra Pharma Prod | New formulation |
| US9427448B2 (en) | 2009-11-11 | 2016-08-30 | The Medicines Company | Methods of treating, reducing the incidence of, and/or preventing ischemic events |
| US20130303477A1 (en) | 2008-05-13 | 2013-11-14 | The Medicines Company | Maintenance of Platelet Inhibition During Antiplatelet Therapy |
| WO2009140092A1 (en) | 2008-05-13 | 2009-11-19 | The Medicines Company | Maintenance of platelet inhibition during antiplatelet therapy |
| US8759316B2 (en) | 2008-05-13 | 2014-06-24 | The Medicines Company | Maintenance of platelet inhibition during antiplatelet therapy |
| US20120141468A1 (en) * | 2008-05-13 | 2012-06-07 | Lisa Ruderman Chen | Maintenance of platelet inhibition during antiplatelet therapy |
| BR112012011298B1 (pt) | 2009-11-11 | 2021-12-14 | Chiesi Farmaceutici S.P.A. | Uso de cangrelor e/ou bivalirudina na preparação de medicamentos e combinação de medicamentos |
| US10376532B2 (en) | 2009-11-11 | 2019-08-13 | Chiesi Farmaceutici, S.P.A. | Methods of treating, reducing the incidence of, and/or preventing ischemic events |
| EP2672975B1 (en) | 2011-02-09 | 2016-04-20 | The Medicines Company | Methods for treating pulmonary hypertension |
| ES2904256T3 (es) | 2013-03-09 | 2022-04-04 | Chiesi Farm Spa | Métodos para tratar, reducir la incidencia de y/o prevenir eventos isquémicos |
| CN103772461A (zh) * | 2014-01-06 | 2014-05-07 | 南京正科制药有限公司 | 一种坎格雷洛晶型ⅰ |
| CN107206014A (zh) | 2015-01-14 | 2017-09-26 | 奇斯药制品公司 | 包含高纯度坎格雷洛的药物制剂以及制备和使用它们的方法 |
| EP3641784A1 (en) | 2017-06-23 | 2020-04-29 | Chiesi Farmaceutici S.p.A. | Method of preventing of systemic-to-pulmonary-artery shunt thrombosis |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5637967B2 (es) * | 1973-05-17 | 1981-09-03 | ||
| JPH01228915A (ja) * | 1988-03-09 | 1989-09-12 | Dai Ichi Seiyaku Co Ltd | Ａｔｐ凍結乾燥製剤 |
| GB8903593D0 (en) * | 1989-02-16 | 1989-04-05 | Pafra Ltd | Storage of materials |
| CZ281415B6 (cs) * | 1989-11-09 | 1996-09-11 | Masarykova Nemocnice S Poliklinikou Iii. Typu | Způsob přípravy přenosového faktoru z buffy coatu savčí krve |
| GB9010742D0 (en) * | 1990-05-14 | 1990-07-04 | Quadrant Bioresources Ltd | Stabilization of biological macromolecular substances |
| AU659645B2 (en) * | 1991-06-26 | 1995-05-25 | Inhale Therapeutic Systems | Storage of materials |
| WO1993011785A1 (en) * | 1991-12-09 | 1993-06-24 | Asahi Kasei Kogyo Kabushiki Kaisha | Stabilized parathyroid hormone composition |
-
1996
- 1996-12-20 ID IDW990482A patent/ID21635A/id unknown
- 1996-12-20 SE SE9604795A patent/SE9604795D0/xx unknown
-
1997
- 1997-12-08 TW TW086118448A patent/TW522015B/zh active
- 1997-12-09 ZA ZA9711055A patent/ZA9711055B/xx unknown
- 1997-12-11 SK SK764-99A patent/SK283137B6/sk not_active IP Right Cessation
- 1997-12-11 SI SI9730403T patent/SI1007094T1/xx unknown
- 1997-12-11 WO PCT/SE1997/002068 patent/WO1998028009A1/en active IP Right Grant
- 1997-12-11 RU RU99115747/14A patent/RU2205012C2/ru active
- 1997-12-11 CZ CZ0220199A patent/CZ300635B6/cs not_active IP Right Cessation
- 1997-12-11 KR KR1019997005584A patent/KR100552880B1/ko not_active IP Right Cessation
- 1997-12-11 EE EEP199900260A patent/EE03857B1/xx unknown
- 1997-12-11 DK DK97950542T patent/DK1007094T3/da active
- 1997-12-11 UA UA99074153A patent/UA66779C2/uk unknown
- 1997-12-11 US US09/043,159 patent/US6114313A/en not_active Expired - Lifetime
- 1997-12-11 AU AU53515/98A patent/AU758857B2/en not_active Expired
- 1997-12-11 ES ES97950542T patent/ES2182133T3/es not_active Expired - Lifetime
- 1997-12-11 EP EP97950542A patent/EP1007094B1/en not_active Expired - Lifetime
- 1997-12-11 CN CN97180744A patent/CN1121875C/zh not_active Expired - Lifetime
- 1997-12-11 PL PL97334006A patent/PL190493B1/pl unknown
- 1997-12-11 PT PT97950542T patent/PT1007094E/pt unknown
- 1997-12-11 DE DE69714616T patent/DE69714616T2/de not_active Expired - Lifetime
- 1997-12-11 AT AT97950542T patent/ATE221787T1/de active
- 1997-12-11 BR BRPI9713974-2A patent/BR9713974B1/pt not_active IP Right Cessation
- 1997-12-11 TR TR1999/01412T patent/TR199901412T2/xx unknown
- 1997-12-11 JP JP52867398A patent/JP4488538B2/ja not_active Expired - Lifetime
- 1997-12-11 HU HU0000572A patent/HU226616B1/hu unknown
- 1997-12-11 NZ NZ336027A patent/NZ336027A/en not_active IP Right Cessation
- 1997-12-11 IL IL13044997A patent/IL130449A0/xx not_active IP Right Cessation
- 1997-12-11 CA CA002275153A patent/CA2275153C/en not_active Expired - Lifetime
- 1997-12-17 SA SA97180719A patent/SA97180719B1/ar unknown
- 1997-12-19 MY MYPI97006175A patent/MY121982A/en unknown
- 1997-12-19 AR ARP970106075A patent/AR010377A1/es active IP Right Grant
-
1999
- 1999-06-03 IS IS5064A patent/IS1897B/is unknown
- 1999-06-21 NO NO19993067A patent/NO327142B1/no not_active IP Right Cessation
-
2000
- 2000-09-05 HK HK00105598A patent/HK1026366A1/xx not_active IP Right Cessation
-
2015
- 2015-09-07 FR FR15C0060C patent/FR15C0060I2/fr active Active
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| AR010377A1 (es) | Composiciones farmaceuticas para secar por congelacion que contienen compuestos de nucleosidos, procedimiento para su preparacion y uso de dichas composiciones para fabricar medicamentos. | |
| CO5070677A1 (es) | Composicion topica para aclarar o reducir la pigmentacion que contiene derivados de resorcinol | |
| HUP0401307A2 (hu) | 5-HT6 hatással rendelkező új indolszármazékok, eljárás az előállításukra, és ezeket tartalmazó gyógyszerkészítmények | |
| RU2003134544A (ru) | Амиды антраниловой кислоты, способы их получения, их применение в качестве антиаритмических средств, а также содержащие их фармацевтические композиции | |
| CO5251381A1 (es) | Derivados de adamantano, un proceso para su preparacion y composiciones farmaceuticas que los contienen | |
| ES2123654T3 (es) | Carbapenems que contienen un grupo fenilo substituido con carboxi, procesos para su preparacion, productos intermedios y uso como antibioticos. | |
| AR050261A2 (es) | Aminoacidos con afinidad por la proteina alfa-2-delta y composiciones farmaceuticas que los contienen y su uso para preparar un medicamento | |
| AR088919A2 (es) | Derivados de pirazol, composiciones que contienen dichos compuestos y uso | |
| DK0447285T3 (da) | Nephtalenderivater, fremgangsmåde til fremstilling heraf og farmaceutiske midler indeholdende dem | |
| UY24409A1 (es) | Inhibidores de la matriz metaloproteasa | |
| AR039826A1 (es) | Composiciones y metodo para el tratamiento de infeccion en ganado vacuno y porcino | |
| BR0016555A (pt) | Composições farmacêuticas que proporcionam concentrações acrescidas de droga | |
| ECSP077402A (es) | Derivados de 2-amido-4-feniltiazol, su preparación y su aplicación en terapéutica | |
| CO4940486A1 (es) | Composiciones anti-fungosas | |
| DK0499521T3 (da) | Hidtil ukendte N-myristoyltransferaseinhibitorer, fremgangsmåde til fremstilling heraf og farmaceutiske midler, som indeholder dem | |
| AR007021A1 (es) | Derivados de 3-descladinosa-2,3-anhidroeritromicina, procedimientos para su preparacion, compuestos para su exclusivo uso en dichos procedimientosy procedimiento para su preparacion, una composicion farmaceutica para tratar infecciones bacterianas y el uso de estos compuestos para preparar medicamentos | |
| AR037940A1 (es) | Compuestos antivirales de piridoquinoxalina | |
| AR040274A1 (es) | Derivados de 1-[(indol-3-il)carbonil]piperazina como agonistas de canabinoides en el tratamiento del dolor y composiciones farmaceuticas | |
| BR9911300A (pt) | Composto, composição farmacêutica, e, uso do composto | |
| AR021826A1 (es) | COMPUESTOS DE 2- FENILPIRAN-4-ONA, PROCESOS PARA PREPARARLOS, USO DE UN COMPUESTO INTERMEDIARIO EN DICHOS, COMPOSICIoN FARMACÉUTICA QUE LOS COMPRENDE Y USO DE DICHOS COMPUESTOS Y DICHA COMPOSICIoN PARA LA FABRICACIoN DE UN MEDICAMENTO | |
| RU99115747A (ru) | Фармацевтические композиции для сушки вымораживанием | |
| AR033828A1 (es) | Benzofenonas y sulfonas como inhibidores de la captacion de glicina y composicion farmaceutica | |
| CO5190692A1 (es) | Derivados de pirrolidin-2,3,4-trion-3-oxima sustituida, procedimientos para su preparacion, medicamentos que contienen estos compuestos y el uso de estos compuestos para la preparacion de medicamentos | |
| AR045912A1 (es) | Composiciones farmaceuticas que contienen derivados de azetidina | |
| AR029001A1 (es) | Derivados de bencil-3,4-metilendioxicinamico y el uso de los mismos para la manufactura de un medicamento |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant, registration |