AR002947A1 - Composicion para la liberacion controlada de un estimulante de xantina o de un derivado de xantina y metodo para preparar dicha composicion - Google Patents
Composicion para la liberacion controlada de un estimulante de xantina o de un derivado de xantina y metodo para preparar dicha composicionInfo
- Publication number
- AR002947A1 AR002947A1 ARP950100500A AR10050095A AR002947A1 AR 002947 A1 AR002947 A1 AR 002947A1 AR P950100500 A ARP950100500 A AR P950100500A AR 10050095 A AR10050095 A AR 10050095A AR 002947 A1 AR002947 A1 AR 002947A1
- Authority
- AR
- Argentina
- Prior art keywords
- composition
- stimulant
- xantina
- preparing
- controlled release
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/52—Purines, e.g. adenine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
- A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Cosmetics (AREA)
Abstract
Una composición para la liberación controlada de una estimulante de xantina o un derivado de xantina, que comprende micropartículas que incluyen una matrizbiodegrable de por lo menos un material soluble en agua y el estimulante, estando dicho estimulante en forma de partículas sólidas que estánsubstancialmente distribuidas uniformemente a través de toda la matriz. Además, se da a conocer un método para preparar esta composición mediante la dispersióndel estimulante en forma de una pluralidad de partículas en una matriz biodegradable. Dicha composición puede administrarse ventajosamente en formaoral aumentando el estado de alerta de un individuo.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/357,689 US5744164A (en) | 1994-12-16 | 1994-12-16 | Sustained release microparticulate caffeine formulation |
Publications (1)
Publication Number | Publication Date |
---|---|
AR002947A1 true AR002947A1 (es) | 1998-05-27 |
Family
ID=23406640
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP950100500A AR002947A1 (es) | 1994-12-16 | 1995-12-11 | Composicion para la liberacion controlada de un estimulante de xantina o de un derivado de xantina y metodo para preparar dicha composicion |
Country Status (21)
Country | Link |
---|---|
US (2) | US5744164A (es) |
EP (2) | EP0716853A1 (es) |
JP (1) | JPH10510529A (es) |
AR (1) | AR002947A1 (es) |
AT (1) | ATE201986T1 (es) |
AU (1) | AU694810B2 (es) |
CA (1) | CA2208149C (es) |
CO (1) | CO4600671A1 (es) |
DE (1) | DE69521328T2 (es) |
DK (1) | DK0789562T3 (es) |
ES (1) | ES2158956T3 (es) |
GR (1) | GR3036501T3 (es) |
HK (1) | HK1000878A1 (es) |
IL (1) | IL116066A (es) |
NZ (1) | NZ295245A (es) |
PE (1) | PE55396A1 (es) |
PT (1) | PT789562E (es) |
RU (1) | RU2144353C1 (es) |
TR (1) | TR199501560A2 (es) |
WO (1) | WO1996018389A1 (es) |
ZA (1) | ZA9510687B (es) |
Families Citing this family (47)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1997000674A1 (en) * | 1995-06-20 | 1997-01-09 | Pharma-Vinci A/S | A method of preparing an oral preparation provided on the outer side with an enteric coating, as well as an oral preparation obtained by the method |
US7163705B2 (en) * | 1998-12-15 | 2007-01-16 | Wm. Wrigley Jr. Company | Coated chewing gum product and method of making |
US6586023B1 (en) | 1998-12-15 | 2003-07-01 | Wm. Wrigley Jr. Company | Process for controlling release of active agents from a chewing gum coating and product thereof |
US6627234B1 (en) | 1998-12-15 | 2003-09-30 | Wm. Wrigley Jr. Company | Method of producing active agent coated chewing gum products |
US6531114B1 (en) | 1999-04-06 | 2003-03-11 | Wm. Wrigley Jr. Company | Sildenafil citrate chewing gum formulations and methods of using the same |
US20020159956A1 (en) * | 1999-04-06 | 2002-10-31 | Ream Ronald L. | Over-coated chewing gum formulations |
US6426090B1 (en) * | 1999-04-06 | 2002-07-30 | Wm. Wrigley Jr. Company | Over-coated product including tableted center and medicament |
US6322806B1 (en) | 1999-04-06 | 2001-11-27 | Wm. Wrigley Jr. Company | Over-coated chewing gum formulations including tableted center |
US7935362B2 (en) * | 1999-04-06 | 2011-05-03 | Wm. Wrigley Jr. Company | Over-coated product including consumable center and medicament |
US6355265B1 (en) | 1999-04-06 | 2002-03-12 | Wm. Wrigley Jr. Company | Over-coated chewing gum formulations |
US6773716B2 (en) | 1999-04-06 | 2004-08-10 | Wm. Wrigley Jr. Company | Over-coated chewing gum formulations |
US6663849B1 (en) | 2000-09-01 | 2003-12-16 | Wm. Wrigley Jr. Company | Antacid chewing gum products coated with high viscosity materials |
US6541048B2 (en) | 1999-09-02 | 2003-04-01 | Wm. Wrigley Jr. Company | Coated chewing gum products containing an acid blocker and process of preparing |
US6645535B2 (en) | 1999-09-02 | 2003-11-11 | Wm. Wrigley Jr. Company | Method of making coated chewing gum products containing various antacids |
US6569472B1 (en) | 2000-09-01 | 2003-05-27 | Wm. Wrigley Jr. Company | Coated chewing gum products containing antacid and method of making |
US9387168B2 (en) | 1999-09-20 | 2016-07-12 | Jack Barreca | Chewing gum with tomatidine |
WO2001021147A1 (en) * | 1999-09-20 | 2001-03-29 | Mastercare | Diet and weight control gum and sucker |
US9253991B2 (en) | 1999-09-20 | 2016-02-09 | Jack Barreca | Chewing gum with B vitamins |
US7892586B2 (en) | 2001-02-22 | 2011-02-22 | Suzanne Jaffe Stillman | Water containing soluble fiber |
US8178150B2 (en) | 2000-02-22 | 2012-05-15 | Suzanne Jaffe Stillman | Water containing soluble fiber |
US7115297B2 (en) | 2000-02-22 | 2006-10-03 | Suzanne Jaffe Stillman | Nutritionally fortified liquid composition with added value delivery systems/elements/additives |
US6572900B1 (en) | 2000-06-09 | 2003-06-03 | Wm. Wrigley, Jr. Company | Method for making coated chewing gum products including a high-intensity sweetener |
US7115288B2 (en) * | 2000-06-09 | 2006-10-03 | Wm. Wrigley Jr. Company | Method for making coated chewing gum products with a coating including an aldehyde flavor and a dipeptide sweetener |
US6444241B1 (en) | 2000-08-30 | 2002-09-03 | Wm. Wrigley Jr. Company | Caffeine coated chewing gum product and process of making |
US6579545B2 (en) | 2000-12-22 | 2003-06-17 | Wm. Wrigley Jr. Company | Coated chewing gum products containing an antigas agent |
US7897141B2 (en) * | 2002-04-01 | 2011-03-01 | Drexel University | Echogenic polymer microcapsules and nanocapsules and methods for production and use thereof |
US20030220351A1 (en) * | 2002-05-24 | 2003-11-27 | Gilbert Gonzales | Enteric coated caffeine tablet |
AU2003292110A1 (en) * | 2002-11-25 | 2004-06-18 | Phares Pharmaceutical Research N.V. | Confectionery composition |
US20050181044A1 (en) * | 2004-02-18 | 2005-08-18 | Jaime Romero | Compositions and methods for timed release of water-soluble nutritional supplements, green coffee extract |
US20050220875A1 (en) * | 2004-03-31 | 2005-10-06 | Agency For Science, Technology And Research | Sustained-release tablet formulation |
FR2883179B1 (fr) | 2005-03-18 | 2009-04-17 | Ethypharm Sa | Comprime enrobe |
US8486452B2 (en) | 2007-07-20 | 2013-07-16 | Mylan Pharmaceuticals Inc. | Stabilized tolterodine tartrate formulations |
US8110226B2 (en) * | 2007-07-20 | 2012-02-07 | Mylan Pharmaceuticals Inc. | Drug formulations having inert sealed cores |
US9173890B2 (en) * | 2007-09-20 | 2015-11-03 | Abbott Cardiovascular Systems Inc. | Sustained release of Apo A-I mimetic peptides and methods of treatment |
US8044021B2 (en) * | 2007-09-20 | 2011-10-25 | Abbott Cardiovascular Systems Inc. | Sustained release of apo A-I mimetic peptides and methods of treatment |
US7985728B1 (en) | 2007-09-20 | 2011-07-26 | Abbott Cardiovascular Systems Inc. | Sustained release of Apo A-I mimetic peptides and methods of treatment |
US8101565B2 (en) * | 2007-09-20 | 2012-01-24 | Abbott Cardiovascular Systems Inc. | Sustained release of Apo A-I mimetic peptides and methods of treatment |
US7985727B1 (en) | 2007-09-20 | 2011-07-26 | Abbott Cardiovascular Systems Inc. | Apo A-I mimetic peptides and methods of treatment |
EP2389174A4 (en) * | 2009-01-22 | 2014-05-07 | Abbot Healthcare Private Ltd | PHARMACEUTICAL COMPOSITION FOR CHRONOTHERAPY |
US8545892B2 (en) | 2009-06-26 | 2013-10-01 | Nano Pharmaceutical Laboratories, Llc | Sustained release beads and suspensions including the same for sustained delivery of active ingredients |
US8992898B2 (en) | 2010-04-17 | 2015-03-31 | Shannon Elizabeth Klingman | Antiperspirants and deodorants |
WO2014197601A1 (en) * | 2013-06-04 | 2014-12-11 | KVK-Tech, Inc. | Controlled release caffeine dosage forms |
JP2018504454A (ja) | 2015-01-12 | 2018-02-15 | ナノ ファーマシューティカル ラボラトリーズ エルエルシーNano Pharmaceutical Laboratories LLC | 積層徐放型マイクロビーズ及びその作製方法 |
KR101644154B1 (ko) * | 2015-09-08 | 2016-07-29 | 주식회사 스킨앤테크 | 수용성 카페인 및 그 제조방법 |
US10582716B1 (en) | 2019-06-14 | 2020-03-10 | Lennham Pharmaceuticals, Inc. | Deuterated caffeine and uses thereof |
US20220288083A1 (en) * | 2021-03-09 | 2022-09-15 | Lennham Pharmaceuticals, Inc. | D9-caffeine compositions and uses thereof |
EP4378456A1 (en) * | 2021-07-30 | 2024-06-05 | Panion & BF Biotech Inc. | Controlled-release oral preparation and preparation method therefor |
Family Cites Families (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3265629A (en) * | 1958-12-22 | 1966-08-09 | Ncr Co | Coating by phase separation |
DE1249219B (de) * | 1958-12-22 | 1967-09-07 | The National Cash Register Company, Dayton, Ohio (V. St. A.) | Herstellen von Mikrokapseln, die eine Emulsion aus Öl in hydrophiler Flüssigkeit enthalten |
DE2010416B2 (de) * | 1970-03-05 | 1979-03-29 | Hoechst Ag, 6000 Frankfurt | Oral anwendbare Arzneiform mit Retardwirkung |
US4001480A (en) * | 1974-08-16 | 1977-01-04 | Swift & Company | Encapsulation process utilizing microorganisms and products produced thereby |
IE55745B1 (en) * | 1983-04-06 | 1991-01-02 | Elan Corp Plc | Sustained absorption pharmaceutical composition |
NZ207813A (en) * | 1983-06-24 | 1986-12-05 | Dridrinks Nv | Effervescent mixture:component(s)coated with water-soluble polysaccharide composition |
DE3474099D1 (en) * | 1983-06-24 | 1988-10-27 | Dridrinks Nv | Treatment of acids as compounds of water-soluble, powdery compositions intended for preparing beverages with lasting gaseous delivery. |
NZ210785A (en) * | 1984-01-13 | 1987-11-27 | Battelle Development Corp | Liquid dispersions of layered controlled release dosage forms |
DE3403329A1 (de) * | 1984-02-01 | 1985-08-01 | Horst Dr. 4019 Monheim Zerbe | Pharmazeutisches produkt in form von pellets mit kontinuierlicher, verzoegerter wirkstoffabgabe |
DE3586600T2 (de) * | 1984-02-10 | 1993-02-18 | Benzon Pharma As | Dosierungsform eine vielzahl mit einer diffusionshuelle ueberzogener einheiten enthaltend. |
DK62184D0 (da) * | 1984-02-10 | 1984-02-10 | Benzon As Alfred | Diffusionsovertrukket polydepotpraeparat |
NL8500724A (nl) * | 1985-03-13 | 1986-10-01 | Univ Groningen | Inrichtingen voor geregelde afgifte van werkzame stoffen, alsmede werkwijze ter vervaardiging daarvan. |
DE3537770A1 (de) * | 1985-10-24 | 1987-04-30 | Basf Ag | Salze mehrwertiger kationen von polymerisaten von konjugierten dienen |
US4853249A (en) * | 1985-11-15 | 1989-08-01 | Taisho Pharmaceutical Co., Ltd. | Method of preparing sustained-release pharmaceutical/preparation |
US5026709A (en) * | 1986-04-07 | 1991-06-25 | Rorer Pharmaceutical Corporation | Method for the preparation of a theophylline sustained release pharmaceutical composition and the composition prepared thereby |
AU7280387A (en) * | 1986-04-07 | 1987-11-09 | Rorer International (Overseas) Inc. | Method for the preparation of a sustained release pharmaceutical composition and the compostion prepared thereby |
GB8613689D0 (en) * | 1986-06-05 | 1986-07-09 | Euro Celtique Sa | Pharmaceutical composition |
US5200193A (en) * | 1987-04-22 | 1993-04-06 | Mcneilab, Inc. | Pharmaceutical sustained release matrix and process |
JP2643222B2 (ja) * | 1988-02-03 | 1997-08-20 | エーザイ株式会社 | 多重層顆粒 |
US4971785A (en) * | 1988-03-14 | 1990-11-20 | Spectrum Consumer Products Co., Inc. | Non-alcoholic delivery system for orally ingestible active ingredients |
US5330766A (en) * | 1989-01-06 | 1994-07-19 | F. H. Faulding & Co. Limited | Sustained release pharmaceutical composition |
US5202128A (en) * | 1989-01-06 | 1993-04-13 | F. H. Faulding & Co. Limited | Sustained release pharmaceutical composition |
CA2007181C (en) * | 1989-01-06 | 1998-11-24 | Angelo Mario Morella | Sustained release pharmaceutical composition |
JPH06316517A (ja) * | 1993-02-22 | 1994-11-15 | Grelan Pharmaceut Co Ltd | 放出制御製剤 |
-
1994
- 1994-12-16 US US08/357,689 patent/US5744164A/en not_active Expired - Lifetime
-
1995
- 1995-03-17 EP EP95103931A patent/EP0716853A1/en not_active Withdrawn
- 1995-11-20 IL IL11606695A patent/IL116066A/xx not_active IP Right Cessation
- 1995-11-27 DK DK95936707T patent/DK0789562T3/da active
- 1995-11-27 ES ES95936707T patent/ES2158956T3/es not_active Expired - Lifetime
- 1995-11-27 JP JP8518527A patent/JPH10510529A/ja active Pending
- 1995-11-27 RU RU97111886A patent/RU2144353C1/ru active
- 1995-11-27 CA CA002208149A patent/CA2208149C/en not_active Expired - Lifetime
- 1995-11-27 AT AT95936707T patent/ATE201986T1/de active
- 1995-11-27 AU AU38542/95A patent/AU694810B2/en not_active Expired
- 1995-11-27 PT PT95936707T patent/PT789562E/pt unknown
- 1995-11-27 DE DE69521328T patent/DE69521328T2/de not_active Expired - Lifetime
- 1995-11-27 NZ NZ295245A patent/NZ295245A/xx not_active IP Right Cessation
- 1995-11-27 WO PCT/IB1995/001056 patent/WO1996018389A1/en active IP Right Grant
- 1995-11-27 EP EP95936707A patent/EP0789562B1/en not_active Expired - Lifetime
- 1995-12-05 PE PE1995286458A patent/PE55396A1/es not_active Application Discontinuation
- 1995-12-11 AR ARP950100500A patent/AR002947A1/es unknown
- 1995-12-12 TR TR95/01560A patent/TR199501560A2/xx unknown
- 1995-12-14 CO CO95059167A patent/CO4600671A1/es unknown
- 1995-12-15 ZA ZA9510687A patent/ZA9510687B/xx unknown
-
1996
- 1996-08-16 US US08/698,621 patent/US5700484A/en not_active Expired - Lifetime
-
1997
- 1997-12-23 HK HK97102557A patent/HK1000878A1/xx not_active IP Right Cessation
-
2001
- 2001-08-31 GR GR20010401361T patent/GR3036501T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
PT789562E (pt) | 2001-10-30 |
EP0716853A1 (en) | 1996-06-19 |
DE69521328D1 (de) | 2001-07-19 |
ZA9510687B (en) | 1996-07-03 |
IL116066A0 (en) | 1996-01-31 |
AU694810B2 (en) | 1998-07-30 |
PE55396A1 (es) | 1996-12-24 |
IL116066A (en) | 2000-10-31 |
CO4600671A1 (es) | 1998-05-08 |
EP0789562A1 (en) | 1997-08-20 |
HK1000878A1 (en) | 2001-10-26 |
US5700484A (en) | 1997-12-23 |
CA2208149A1 (en) | 1996-06-20 |
NZ295245A (en) | 1999-01-28 |
ES2158956T3 (es) | 2001-09-16 |
US5744164A (en) | 1998-04-28 |
JPH10510529A (ja) | 1998-10-13 |
CA2208149C (en) | 2007-03-27 |
DE69521328T2 (de) | 2002-01-17 |
RU2144353C1 (ru) | 2000-01-20 |
AU3854295A (en) | 1996-07-03 |
DK0789562T3 (da) | 2001-09-03 |
EP0789562B1 (en) | 2001-06-13 |
ATE201986T1 (de) | 2001-06-15 |
GR3036501T3 (en) | 2001-11-30 |
WO1996018389A1 (en) | 1996-06-20 |
TR199501560A2 (tr) | 1996-07-21 |
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