AP27A - Substituted indoloquinoxalines. - Google Patents
Substituted indoloquinoxalines. Download PDFInfo
- Publication number
- AP27A AP27A APAP/P/1987/000055A AP8700055A AP27A AP 27 A AP27 A AP 27A AP 8700055 A AP8700055 A AP 8700055A AP 27 A AP27 A AP 27A
- Authority
- AP
- ARIPO
- Prior art keywords
- group
- lower alkyl
- iodine
- substituted
- adducts
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE8600260A SE8600260D0 (sv) | 1986-01-21 | 1986-01-21 | Substituerade indolokinoxaliner |
Publications (2)
Publication Number | Publication Date |
---|---|
AP8700055A0 AP8700055A0 (en) | 1986-11-01 |
AP27A true AP27A (en) | 1988-12-02 |
Family
ID=20363170
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
APAP/P/1987/000055A AP27A (en) | 1986-01-21 | 1987-01-09 | Substituted indoloquinoxalines. |
Country Status (19)
Country | Link |
---|---|
US (1) | US4990510A (da) |
EP (1) | EP0238459B1 (da) |
JP (1) | JPH07107066B2 (da) |
KR (1) | KR880700801A (da) |
AP (1) | AP27A (da) |
AT (1) | ATE74920T1 (da) |
AU (1) | AU606047B2 (da) |
CA (1) | CA1303613C (da) |
DE (1) | DE3778190D1 (da) |
DK (1) | DK492587D0 (da) |
ES (1) | ES2037105T3 (da) |
FI (1) | FI883373A0 (da) |
HU (1) | HU201937B (da) |
IL (1) | IL81209A (da) |
NO (1) | NO873945D0 (da) |
OA (1) | OA08744A (da) |
RU (1) | RU1776259C (da) |
SE (1) | SE8600260D0 (da) |
WO (1) | WO1987004436A1 (da) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE8600261D0 (sv) * | 1986-01-21 | 1986-01-21 | Lundblad Leif | Indolokinoxaliner med substituenter i 6-position som innehaller cykliska grupper |
US5597921A (en) * | 1993-04-22 | 1997-01-28 | Taisho Pharmaceutical Co., Ltd. | Indolo[2,3-b]quinoxaline derivatives |
US5700823A (en) * | 1994-01-07 | 1997-12-23 | Sugen, Inc. | Treatment of platelet derived growth factor related disorders such as cancers |
SE504289C2 (sv) * | 1994-06-23 | 1996-12-23 | Leif J I Lundblad | Användning av vissa indolo-2,3b-kinoxaliner för framställning av ett läkemedel för inhibering av enzymet HIV-integras |
SE504862C2 (sv) * | 1994-12-27 | 1997-05-20 | Leif J I Lundblad | Användning av vissa indolo-§2,3b¤-kinoxaliner för framställning av ett läkemedel för skydd av DNA i initieringsfasen och/eller promotionsfasen av karcinogenes och för förhindrande av oxidativ stress i patienter med sjukdomar relaterade till fria radikaler |
US5721277A (en) * | 1995-04-21 | 1998-02-24 | Sugen, Inc. | Compounds and methods for inhibiting hyper-proliferative cell growth |
US6331555B1 (en) | 1995-06-01 | 2001-12-18 | University Of California | Treatment of platelet derived growth factor related disorders such as cancers |
US6465466B1 (en) | 1995-12-22 | 2002-10-15 | Leif J. I. Lundblad | Uses of indolo-2 [2,3b] -quinoxalines |
US6316479B1 (en) | 1997-05-19 | 2001-11-13 | Sugen, Inc. | Isoxazole-4-carboxamide compounds active against protein tryosine kinase related disorders |
SE9704723D0 (sv) * | 1997-12-17 | 1997-12-17 | Leif J I Lundblad | Ligands |
SE516067C2 (sv) * | 2000-02-18 | 2001-11-12 | Lundblad Leif J I | Användning av en förening för framställning av ett läkemedel |
US6333327B2 (en) * | 2000-02-18 | 2001-12-25 | Leif J. I. Lundblad | Method for the treatment of Multiple Sclerosis |
GB0022922D0 (en) * | 2000-09-19 | 2000-11-01 | Chapman Robert E | Compounds for use in medicine |
SE529777C2 (sv) * | 2006-01-23 | 2007-11-20 | Vironova Ab | Nya föreningar och användning därav |
DE602008001795D1 (de) | 2008-04-30 | 2010-08-26 | Univ Duisburg Essen | IndolÄ2,3-bÜ-, IndenÄ1,2-bÜ- und IndenÄ2,1-bÜpyridoÄ2,3-fÜ Quinoxalin-3-Carboxylsäuren und Ester, Verfahren zu ihrer Herstellung und ihre Verwendung als Antivirus- und Antitumormittel |
EP2489354A1 (en) | 2011-02-18 | 2012-08-22 | Vironova AB | Pharmaceutical formulation of B220 for topical treatment of herpes |
CN105061432B (zh) * | 2015-07-16 | 2017-09-29 | 河北大学 | 6H‑吲哚[2,3‑b]喹喔啉衍生物、药物组合物及其制备和应用 |
WO2022002897A1 (en) * | 2020-06-29 | 2022-01-06 | Vironova Medical Ab | 6h-indolo[2,3-b]quinoxaline derivatives useful in therapy |
WO2022002898A1 (en) * | 2020-06-29 | 2022-01-06 | Vironova Medical Ab | 6h-indolo(2,3-b)quinoxaline derivatives useful in therapy in particular in a virus infection |
-
1986
- 1986-01-21 SE SE8600260A patent/SE8600260D0/xx unknown
-
1987
- 1987-01-08 IL IL81209A patent/IL81209A/xx not_active IP Right Cessation
- 1987-01-09 AP APAP/P/1987/000055A patent/AP27A/en active
- 1987-01-19 AT AT87850012T patent/ATE74920T1/de not_active IP Right Cessation
- 1987-01-19 DE DE8787850012T patent/DE3778190D1/de not_active Expired - Lifetime
- 1987-01-19 US US07/102,147 patent/US4990510A/en not_active Expired - Lifetime
- 1987-01-19 HU HU847A patent/HU201937B/hu not_active IP Right Cessation
- 1987-01-19 ES ES198787850012T patent/ES2037105T3/es not_active Expired - Lifetime
- 1987-01-19 WO PCT/SE1987/000019 patent/WO1987004436A1/en active Application Filing
- 1987-01-19 AU AU68995/87A patent/AU606047B2/en not_active Ceased
- 1987-01-19 EP EP87850012A patent/EP0238459B1/en not_active Expired - Lifetime
- 1987-01-19 JP JP62500757A patent/JPH07107066B2/ja not_active Expired - Fee Related
- 1987-01-20 CA CA000527660A patent/CA1303613C/en not_active Expired - Lifetime
- 1987-09-18 DK DK492587A patent/DK492587D0/da not_active Application Discontinuation
- 1987-09-21 KR KR870700852A patent/KR880700801A/ko not_active Application Discontinuation
- 1987-09-21 NO NO873945A patent/NO873945D0/no unknown
-
1988
- 1988-07-15 FI FI883373A patent/FI883373A0/fi not_active Application Discontinuation
- 1988-07-19 RU SU884356314A patent/RU1776259C/ru active
- 1988-07-21 OA OA59390A patent/OA08744A/xx unknown
Non-Patent Citations (1)
Title |
---|
CHEMICAL ABSTRACTS, Vol. 84 (1986) No. 180.1667 Sci Phorm, 1975 (4) p. 249-260 * |
Also Published As
Publication number | Publication date |
---|---|
KR880700801A (ko) | 1988-04-12 |
HUT47937A (en) | 1989-04-28 |
DE3778190D1 (de) | 1992-05-21 |
SE8600260D0 (sv) | 1986-01-21 |
DK492587A (da) | 1987-09-18 |
OA08744A (en) | 1989-03-31 |
JPH07107066B2 (ja) | 1995-11-15 |
IL81209A (en) | 1991-04-15 |
AU6899587A (en) | 1987-08-14 |
EP0238459B1 (en) | 1992-04-15 |
JPS63502588A (ja) | 1988-09-29 |
CA1303613C (en) | 1992-06-16 |
NO873945L (no) | 1987-09-21 |
HU201937B (en) | 1991-01-28 |
ATE74920T1 (de) | 1992-05-15 |
EP0238459A1 (en) | 1987-09-23 |
IL81209A0 (en) | 1987-08-31 |
FI883373A (fi) | 1988-07-15 |
ES2037105T3 (es) | 1993-06-16 |
AP8700055A0 (en) | 1986-11-01 |
US4990510A (en) | 1991-02-05 |
NO873945D0 (no) | 1987-09-21 |
FI883373A0 (fi) | 1988-07-15 |
WO1987004436A1 (en) | 1987-07-30 |
RU1776259C (ru) | 1992-11-15 |
AU606047B2 (en) | 1991-01-31 |
DK492587D0 (da) | 1987-09-18 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
AP27A (en) | Substituted indoloquinoxalines. | |
RU2126007C1 (ru) | Производные индолокарбазолимида, смесь их изомеров и их соли, фармацевтическая композиция с активностью, ингибирующей протеинкиназу c или киназу легкой миозиновой цепи или подавляющей иммунные реакции | |
US5597831A (en) | 6-[X-(2-hydroxyethyl) aminoalkyl]-5,11-dioxo-5,6-dihydro-11-H-indeno[1,2-c]isoquinolines and their use as antineoplastic agents | |
HU201773B (en) | Process for producing rebeccamycin analogs and pharmaceutical compositions comprising such active ingredient | |
CN114573586B (zh) | 一种抑制布鲁顿酪氨酸激酶活性的多环化合物、药物组合物及其应用 | |
CN101558062A (zh) | 作为激酶抑制剂的吲哚基马来酰亚胺衍生物 | |
JPS6225670B2 (da) | ||
IE921770A1 (en) | Substituted diaminophthalimides and analogues | |
US5652239A (en) | Pyridazinedione derivatives useful in treatment of neurological disorders | |
RU2120939C1 (ru) | 6-[x-(2-гидроксиэтил)аминоалкил]-5,11-диоксо-5,6-дигидро-11h-инде- но/1,2-с/изохинолины или их соли с неорганическими и органическими кислотами, способы их получения и фармацевтическая композиция на их основе | |
JPS6322082A (ja) | 1―(ヒドロキシスチリル)―5h―2,3―ベンゾジアゼピン誘導体およびその製造方法、並びに前記誘導体を含む薬剤 | |
CA1131631A (en) | Quinazoline derivatives and pharmaceutical preparations | |
KR840000794B1 (ko) | 퀴나졸린 유도체의 제조방법 | |
US4916124A (en) | Indoloquinoxalines with substituents in 6-position containing cyclic groups as antiviral agents | |
NL8600976A (nl) | (-)-1 beta-ethyl-1 alfa-hydroxymethyl-1,2,3,4,6,7,12,12 b alfa-octahydroindool2,3-achinolizine, werkwijze voor de bereiding ervan en farmaceutische preparaten met een dergelijke verbinding erin. | |
US4482714A (en) | Pyrazino[2',3'-3,4]pyrido[1,2-a]indole derivatives | |
US4515949A (en) | [2-(1H-indol-1-yl)ethyl]-2-piperazine and pyrido[1,2-a]indol-9-one as intermediates for pyrazino(2,3-3,4)pyrido(1,2-a) indoles which are useful for treating hypertension in mammals | |
US5216017A (en) | Pyrrolo[2,3-b]indole-ketones and analogs | |
US4661297A (en) | Basic ethers of 7-oxo-7H-benzo(c) fluorene and a process for their production | |
AU634654B2 (en) | Pyrrolo(2,3-b)indole-ketones and analogs, a process for their preparation and their use as medicaments | |
SU1746885A3 (ru) | Способ получени 7-амино-5-имино-2,3-дигидро-5Н-тиазоло[3,2-а]пиримидина, или его фармацевтически приемлемых кислотно-аддитивных солей, или гидратов | |
PL185709B1 (pl) | Nowy monohydrat polimorfu II 6-N-(L-Ala-L-Ala)-trowafloksacyny i środek farmaceutyczny | |
EP0558613A1 (fr) | Derives de pyridobenzoindole, leur preparation et les compositions pharmaceutiques qui les contiennent | |
FR2661411A1 (fr) | Nouveaux derives de pyridobenzoindole, leur preparation et les compositions qui les contiennent. | |
CS225848B2 (cs) | Způsob výroby 9-[3-(3,5-cis-dimethylpiperazino)propyl]l<arbazolu |