ZA976713B - Method of preparation of physostigmine carbamate derivatives from eseroline ethers. - Google Patents

Method of preparation of physostigmine carbamate derivatives from eseroline ethers.

Info

Publication number: ZA976713B
Authority: ZA; South Africa
Prior art keywords: preparation; carbamate derivatives; eseroline; ethers; physostigmine carbamate
Prior art date: 1996-12-19

Application number

ZA9706713A

Other languages

English (en)

Inventor

Thomas B K Lee

Barbara S Rauckman

Zhongli Gao

Original Assignee

Hoechst Marion Roussel Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-12-19

Filing date

1997-07-28

Publication date

1998-06-19

1997-07-28 Application filed by Hoechst Marion Roussel Inc filed Critical Hoechst Marion Roussel Inc

1998-06-19 Publication of ZA976713B publication Critical patent/ZA976713B/xx

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

ZA9706713A 1996-12-19 1997-07-28 Method of preparation of physostigmine carbamate derivatives from eseroline ethers. ZA976713B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US08/769,409 US5677457A (en)	1996-12-19	1996-12-19	Method of preparation of physostigmine carbamate derivatives from eseroline ethers

Publications (1)

Publication Number	Publication Date
ZA976713B true ZA976713B (en)	1998-06-19

Family

ID=25085359

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA9706713A ZA976713B (en)	1996-12-19	1997-07-28	Method of preparation of physostigmine carbamate derivatives from eseroline ethers.

Country Status (13)

Country	Link
US (1)	US5677457A (fr)
EP (1)	EP0946560A1 (fr)
JP (1)	JP2001506259A (fr)
KR (1)	KR20000062263A (fr)
AR (1)	AR009311A1 (fr)
AU (1)	AU715483B2 (fr)
BR (1)	BR9714046A (fr)
CA (1)	CA2273180C (fr)
HU (1)	HUP0000046A3 (fr)
IL (1)	IL130460A0 (fr)
NO (1)	NO993011L (fr)
WO (1)	WO1998027096A1 (fr)
ZA (1)	ZA976713B (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6297237B1 (en) *	1997-10-10	2001-10-02	Chiesi Farmaceutici S.P.A.	Process for the preparation of aminocarbonyl derivatives of geneseroline having selective brain anticholinesterase activity
US6495700B1 (en)	2002-01-09	2002-12-17	Axonyx, Inc.	Process for producing phenserine and its analog
CN1898201A (zh) *	2003-10-21	2007-01-17	森蒂有限公司	可抑制胆碱酯酶和释放药理学活性试剂的氨基甲酸酯
JP2010518010A (ja) *	2007-02-02	2010-05-27	コルシド・ファーマシューティカルズ・インコーポレイテッド	コリンエステラーゼを阻害する化合物
SE531698C2 (sv)	2007-07-12	2009-07-07	Respiratorius Ab	Nya bronkdilaterande a,b-omättade amider
US20090048229A1 (en) *	2007-07-18	2009-02-19	Rupniak Nadia M J	Methods for promoting wakefulness
US8593728B2 (en) *	2009-02-19	2013-11-26	Toyota Motor Engineering & Manufacturing North America, Inc.	Multilayer photonic structures

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DE2905054C3 (de) *	1979-02-08	1982-04-29	Schering Ag, 1000 Berlin Und 4619 Bergkamen	Verfahren zur Herstellung von 4-Hydroxyindolen
IT1199076B (it) *	1984-03-01	1988-12-30	Consiglio Nazionale Ricerche	Derivati della fisostigmina con proprieta'di inibizione della aceticolinesterasi e relativo procedimento di produzione
US4791107A (en) *	1986-07-16	1988-12-13	Hoechst-Roussel Pharmaceuticals, Inc.	Memory enhancing and analgesic 1,2,3,3A,8,8A-hexahydro-3A,8 (and) 1,3A,8)-di(and tri)methylpyrrolo(2,3-B)indoles, compositions and use
US5187165A (en) *	1987-05-15	1993-02-16	Hoechst-Roussel Pharmaceuticals Inc.	Memory enhancing and analgesic 1,2,3a,8,8a-hexahydro-3a,8(and 1,3a,8)-di(and tri)methylpyrrolo[2,3-b]indoles
US4971992A (en) *	1989-03-27	1990-11-20	Hoechst-Roussel Pharmaceuticals Inc.	Carbonate derivatives of eseroline
ES2075102T3 (es) *	1989-09-19	1995-10-01	Hoechst Roussel Pharma	Procedimiento para la resolucion quimica de (+/-)-1,3-dimetiloxiindoliletilaminas 5-alcoxi sustituidas.
US4937341A (en) *	1989-09-28	1990-06-26	Hoechst-Roussel Pharmaceuticals Inc.	Process for preparing N-aminocarbarbamates related to physostigmine
US4914102A (en) *	1989-09-28	1990-04-03	Hoechst Roussel Pharmaceuticals, Inc.	N-aminocarbamates related to physostigmine, pharmacentical compositions and use
US5260452A (en) *	1989-11-03	1993-11-09	Hoechst-Roussel Pharmaceuticals Inc.	4- and 6-carbamates related to physostigmine and intermediates for the preparation thereof
US5177101A (en) *	1989-11-30	1993-01-05	Hoechst-Roussel Pharmaceuticals Incorporated	Memory enhancing and analgesic aminocarbonylcarbamates related to physostigmine
US5077289A (en) *	1989-11-30	1991-12-31	Hoechst Roussel Pharmaceuticals Inc.	Memory enhancing and analgesic aminocarbonylcarbamates related to physostigmine
US5274117A (en) *	1990-01-22	1993-12-28	Hoechst-Roussel Pharmaceuticals, Inc.	Process for the enantioselective synthesis of intermediates used in the preparation of physostigmine
US4983616A (en) *	1990-02-01	1991-01-08	Hoechst-Roussel Pharmaceuticals Inc.	Hexahydropyrrolo(2,3-B)indole carbamates, ureas, amides and related compounds
US5091541A (en) *	1990-02-01	1992-02-25	Hoechst-Roussel Pharmaceuticals Inc.	Hexahydropyrrolo(2,3-B)indole carbamates, ureas, amides and related compounds
US5216017A (en) *	1990-05-11	1993-06-01	Hoechst-Roussel Pharmaceuticals Incorporated	Pyrrolo[2,3-b]indole-ketones and analogs
US5264587A (en) *	1990-05-17	1993-11-23	Hoechst-Roussel Pharmaceuticals Incorporated	Method of preparing α-oxopyrrolo[2,3-b]indole acetic acids and derivatives
US5173497A (en) *	1990-05-17	1992-12-22	Hoechst-Roussel Pharmaceuticals Incorporated	Alpha-oxopyrrolo[2,3-B]indole acetic acids, esters, amides and related analogs
EP0538248B1 (fr) *	1990-06-27	1998-02-11	Hoechst Marion Roussel, Inc.	Tetrahydroisoquinolinylcarbamates de 1,2,3,3a,8,8a-hexahydro-1,3a,8-trimethylpyrrolo [2,3-b] indole
US5231093A (en) *	1991-10-01	1993-07-27	Hoechst-Roussel Pharmaceuticals Incorporated	Carbamate derivatives of 4-amino-3-isoxazolidinones, 3-amino-1-hydroxypyrrolidin-2-ones and 1-amino-1-cyclopropanecarboxylic acid analogs
US5153193A (en) *	1991-10-01	1992-10-06	Hoechst-Roussel Pharmaceuticals Incorporated	Carbamate derivatives of 4-amino-3-isoxazolidinones, 3-amino-1-hydroxypyrrolidin-2-ones and 1-amino-1-cyclopropanecarboxylic acid analogs
US5234941A (en) *	1991-10-01	1993-08-10	Hoechst-Roussel Pharmaceuticals Incorporated	Carbamate derivatives of 4-amino-3-isoxazolidinones, 3-amino-1-hydroxypyrrolidin-2-ones and 1-amino-1-cyclopropanecarboxylic acid analogs
US5302721A (en) *	1992-07-21	1994-04-12	Hoechst-Roussel Pharmaceuticals Incorporated	Method of preparation of physostigmine carbamate derivatives from eseretholes
NZ248180A (en) *	1992-07-21	1995-02-24	Hoechst Roussel Pharma	Process for the preparation of physostigmine carbamate derivatives
US5350762A (en) *	1993-03-08	1994-09-27	Hoechst-Roussel Pharmaceuticals Incorporated	Tetrahydrocyclopent[B]indole methanamines and related compounds

1996
- 1996-12-19 US US08/769,409 patent/US5677457A/en not_active Expired - Fee Related
1997
- 1997-07-21 BR BR9714046-5A patent/BR9714046A/pt not_active IP Right Cessation
- 1997-07-21 CA CA002273180A patent/CA2273180C/fr not_active Expired - Fee Related
- 1997-07-21 HU HU0000046A patent/HUP0000046A3/hu unknown
- 1997-07-21 JP JP52766298A patent/JP2001506259A/ja active Pending
- 1997-07-21 AU AU38008/97A patent/AU715483B2/en not_active Ceased
- 1997-07-21 EP EP97934961A patent/EP0946560A1/fr not_active Withdrawn
- 1997-07-21 IL IL13046097A patent/IL130460A0/xx unknown
- 1997-07-21 KR KR1019997005614A patent/KR20000062263A/ko not_active Application Discontinuation
- 1997-07-21 WO PCT/US1997/012367 patent/WO1998027096A1/fr not_active Application Discontinuation
- 1997-07-28 ZA ZA9706713A patent/ZA976713B/xx unknown
- 1997-08-25 AR ARP970103837A patent/AR009311A1/es unknown
1999
- 1999-06-18 NO NO993011A patent/NO993011L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
NO993011D0 (no)	1999-06-18
HUP0000046A3 (en)	2000-09-28
CA2273180C (fr)	2002-10-29
JP2001506259A (ja)	2001-05-15
CA2273180A1 (fr)	1998-06-25
AU715483B2 (en)	2000-02-03
AU3800897A (en)	1998-07-15
KR20000062263A (ko)	2000-10-25
WO1998027096A1 (fr)	1998-06-25
NO993011L (no)	1999-08-18
HUP0000046A2 (hu)	2000-06-28
US5677457A (en)	1997-10-14
AR009311A1 (es)	2000-04-12
BR9714046A (pt)	2000-05-09
IL130460A0 (en)	2000-06-01
EP0946560A1 (fr)	1999-10-06

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