ZA962342B - Process for preparing olanzapine. - Google Patents

Process for preparing olanzapine.

Info

Publication number
ZA962342B
ZA962342B ZA9602342A ZA962342A ZA962342B ZA 962342 B ZA962342 B ZA 962342B ZA 9602342 A ZA9602342 A ZA 9602342A ZA 962342 A ZA962342 A ZA 962342A ZA 962342 B ZA962342 B ZA 962342B
Authority
ZA
South Africa
Prior art keywords
preparing olanzapine
olanzapine
preparing
Prior art date
Application number
ZA9602342A
Inventor
Charles Arthur Bunnell
Barry Arnold Hendriksen
Samuel Dean Larsen
Terrence Michael Hotten
David Edward Tupper
Original Assignee
Lilly Co Eli
Lilly Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23621056&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ZA962342(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lilly Co Eli, Lilly Industries Ltd filed Critical Lilly Co Eli
Publication of ZA962342B publication Critical patent/ZA962342B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Epidemiology (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Medicinal Preparation (AREA)
ZA9602342A 1995-03-24 1996-03-22 Process for preparing olanzapine. ZA962342B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US40956695A 1995-03-24 1995-03-24

Publications (1)

Publication Number Publication Date
ZA962342B true ZA962342B (en) 1997-09-22

Family

ID=23621056

Family Applications (2)

Application Number Title Priority Date Filing Date
ZA9602342A ZA962342B (en) 1995-03-24 1996-03-22 Process for preparing olanzapine.
ZA9602344A ZA962344B (en) 1995-03-24 1996-03-22 Process and crystal forms of 2-methyl-thieno-benzodiazepine.

Family Applications After (1)

Application Number Title Priority Date Filing Date
ZA9602344A ZA962344B (en) 1995-03-24 1996-03-22 Process and crystal forms of 2-methyl-thieno-benzodiazepine.

Country Status (49)

Country Link
US (1) US5736541A (en)
EP (3) EP1445259B1 (en)
JP (1) JPH11502535A (en)
KR (1) KR100399688B1 (en)
CN (1) CN1065536C (en)
AP (1) AP828A (en)
AR (2) AR010448A1 (en)
AT (4) AT406771B (en)
AU (1) AU706471B2 (en)
BG (1) BG62619B1 (en)
BR (1) BR9607790A (en)
CA (1) CA2214005C (en)
CH (1) CH690579A5 (en)
CO (1) CO4650278A1 (en)
CZ (1) CZ292688B6 (en)
DE (4) DE69614426T2 (en)
DK (4) DK0733635T3 (en)
EA (1) EA000149B1 (en)
EE (1) EE03489B1 (en)
EG (1) EG23659A (en)
ES (3) ES2159346T3 (en)
FI (1) FI973750A0 (en)
GB (1) GB2313835B (en)
HK (1) HK1013988A1 (en)
HU (1) HU224989B1 (en)
IL (1) IL117610A (en)
IS (1) IS1896B (en)
LT (1) LT4349B (en)
LU (1) LU90096B1 (en)
LV (1) LV12018B (en)
MY (1) MY114701A (en)
NO (1) NO314663B1 (en)
NZ (1) NZ306110A (en)
OA (1) OA10510A (en)
PA (1) PA8353701A1 (en)
PE (1) PE44897A1 (en)
PL (1) PL183723B1 (en)
PT (3) PT1095941E (en)
RO (1) RO118872B1 (en)
SE (1) SE9703205D0 (en)
SI (4) SI1445259T1 (en)
SK (1) SK284143B6 (en)
SV (1) SV1996000031A (en)
TR (1) TR199701017T1 (en)
TW (2) TW442488B (en)
UA (1) UA44765C2 (en)
WO (1) WO1996030375A1 (en)
YU (1) YU49478B (en)
ZA (2) ZA962342B (en)

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EG23659A (en) * 1995-03-24 2007-03-26 Lilly Co Eli Process and crystal forms of methyl-thieno-benzodiazepine
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UA57727C2 (en) * 1996-03-11 2003-07-15 Елі Ліллі Енд Компані Method for treating excessive aggression
AU721338B2 (en) * 1996-03-25 2000-06-29 Eli Lilly And Company Method for treating pain
BR9708254A (en) * 1996-03-25 1999-08-03 Lilly Co Eli Method for treating pain
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RS49597B (en) * 1996-09-23 2007-06-04 Eli Lilly And Company, Olanzapine dihydrate d
ZA978515B (en) * 1996-09-23 1999-03-23 Lilly Co Eli Intermediates and process for preparing olanzapine
DK1155696T3 (en) * 1997-04-15 2004-07-12 Lilly Co Eli Use of olanzapine in the manufacture of a drug for neuroprotection
US20030022889A1 (en) * 1997-04-15 2003-01-30 Bymaster Franklin P. Method for providing neuro-protective effects
WO1998046596A1 (en) * 1997-04-15 1998-10-22 Eli Lilly And Company Method for providing neuro-protective effects
ZA982917B (en) * 1997-04-15 1999-10-06 Lilly Co Eli Method for treating cerebral focal stroke.
USRE43932E1 (en) 1997-07-18 2013-01-15 Novartis Ag Crystal modification of a N-phenyl-2-pyrimidineamine derivative, processes for its manufacture and its use
US6617321B2 (en) 1997-09-30 2003-09-09 Eli Lilly And Company 2-methyl-thieno-benzodiazepine formulation
EA002580B1 (en) * 1998-09-30 2002-06-27 Эли Лилли Энд Компани 2-methyl-thieno-benzodiazepine formulation
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US20050025791A1 (en) * 2002-06-21 2005-02-03 Julius Remenar Pharmaceutical compositions with improved dissolution
US7927613B2 (en) * 2002-02-15 2011-04-19 University Of South Florida Pharmaceutical co-crystal compositions
US7790905B2 (en) * 2002-02-15 2010-09-07 Mcneil-Ppc, Inc. Pharmaceutical propylene glycol solvate compositions
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US7829700B2 (en) 2004-09-06 2010-11-09 Shasun Chemicals And Drugs Limited Process for preparation of a pharmaceutically pure polymorphic form I of Olanzapine
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Also Published As

Publication number Publication date
SV1996000031A (en) 1998-03-27
KR19980703188A (en) 1998-10-15
DE69614426T2 (en) 2002-05-23
GB2313835A (en) 1997-12-10
AU5427996A (en) 1996-10-16
EA000149B1 (en) 1998-10-29
DE69614426D1 (en) 2001-09-20
YU17796A (en) 1999-03-04
KR100399688B1 (en) 2004-02-18
SI9620040A (en) 1998-06-30
CZ300097A3 (en) 1997-12-17
HUP9802824A2 (en) 1999-06-28
ATA902196A (en) 2000-01-15
LV12018B (en) 1998-09-20
BR9607790A (en) 1998-07-07
CZ292688B6 (en) 2003-11-12
LV12018A (en) 1998-04-20
DK1095941T3 (en) 2004-02-16
UA44765C2 (en) 2002-03-15
EE03489B1 (en) 2001-08-15
SK121897A3 (en) 1998-03-04
BG101900A (en) 1999-03-31
AU706471B2 (en) 1999-06-17
HK1013988A1 (en) 1999-09-17
CH690579A5 (en) 2000-10-31
ATE251627T1 (en) 2003-10-15
EE9700232A (en) 1998-04-15
GB9719819D0 (en) 1997-11-19
DE19681286T1 (en) 1998-04-02
LT97148A (en) 1998-01-26
ATE331719T1 (en) 2006-07-15
DK1445259T3 (en) 2006-10-16
IS1896B (en) 2003-10-20
SI9620040B (en) 2002-02-28
DE69630324T2 (en) 2004-07-29
GB2313835B (en) 1998-09-16
TW442488B (en) 2001-06-23
PL183723B1 (en) 2002-07-31
MX9707183A (en) 1997-11-29
IS4564A (en) 1997-09-22
HUP9802824A3 (en) 2000-01-28
AT406771B (en) 2000-08-25
RO118872B1 (en) 2003-12-30
EP1445259B1 (en) 2006-06-28
HU224989B1 (en) 2006-05-29
SI1095941T1 (en) 2003-12-31
FI973750A (en) 1997-09-22
TW513432B (en) 2002-12-11
DK108997A (en) 1997-11-12
PT1095941E (en) 2004-02-27
US5736541A (en) 1998-04-07
DE69630324D1 (en) 2003-11-13
AR002719A1 (en) 1998-04-29
IL117610A0 (en) 1996-07-23
IL117610A (en) 2001-08-26
NO974365L (en) 1997-09-22
SE9703205L (en) 1997-09-05
PA8353701A1 (en) 1998-09-18
PT1445259E (en) 2006-10-31
ES2208220T3 (en) 2004-06-16
NO974365D0 (en) 1997-09-22
WO1996030375A1 (en) 1996-10-03
NZ306110A (en) 1998-09-24
CN1065536C (en) 2001-05-09
ZA962344B (en) 1997-09-22
CA2214005C (en) 2001-07-03
JPH11502535A (en) 1999-03-02
EP1095941A1 (en) 2001-05-02
EP0733635B1 (en) 2001-08-16
EG23659A (en) 2007-03-26
ATE204280T1 (en) 2001-09-15
ES2159346T3 (en) 2001-10-01
EP1095941B1 (en) 2003-10-08
CN1179160A (en) 1998-04-15
DK0733635T3 (en) 2001-10-08
PL322501A1 (en) 1998-02-02
CA2214005A1 (en) 1996-10-03
FI973750A0 (en) 1997-09-22
TR199701017T1 (en) 1998-01-21
DE69636313T2 (en) 2007-05-31
YU49478B (en) 2006-05-25
AP9701065A0 (en) 1997-10-31
AR010448A1 (en) 2000-06-28
SI1445259T1 (en) 2006-10-31
EP0733635A1 (en) 1996-09-25
PT733635E (en) 2001-12-28
EA199700262A1 (en) 1998-02-26
MY114701A (en) 2002-12-31
BG62619B1 (en) 2000-03-31
SI0733635T1 (en) 2002-06-30
AP828A (en) 2000-04-28
SK284143B6 (en) 2004-10-05
SE9703205D0 (en) 1997-09-05
LU90096B1 (en) 1997-07-22
CO4650278A1 (en) 1998-09-03
NO314663B1 (en) 2003-04-28
OA10510A (en) 2002-04-24
EP1445259A1 (en) 2004-08-11
LT4349B (en) 1998-05-25
ES2266719T3 (en) 2007-03-01
DE69636313D1 (en) 2006-08-10
PE44897A1 (en) 1997-10-22

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