ZA946125B - Novel macrolides and the use thereof - Google Patents
Novel macrolides and the use thereofInfo
- Publication number
- ZA946125B ZA946125B ZA946125A ZA946125A ZA946125B ZA 946125 B ZA946125 B ZA 946125B ZA 946125 A ZA946125 A ZA 946125A ZA 946125 A ZA946125 A ZA 946125A ZA 946125 B ZA946125 B ZA 946125B
- Authority
- ZA
- South Africa
- Prior art keywords
- novel macrolides
- macrolides
- novel
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/351—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom not condensed with another ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
- C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/02—Oxygen as only ring hetero atoms
- C12P17/08—Oxygen as only ring hetero atoms containing a hetero ring of at least seven ring members, e.g. zearalenone, macrolide aglycons
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/44—Preparation of O-glycosides, e.g. glucosides
- C12P19/58—Preparation of O-glycosides, e.g. glucosides having an oxygen atom of the saccharide radical directly bound through only acyclic carbon atoms to a non-saccharide heterocyclic ring, e.g. bleomycin, phleomycin
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Microbiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- General Engineering & Computer Science (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Diabetes (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH243593 | 1993-08-16 |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA946125B true ZA946125B (en) | 1995-02-16 |
Family
ID=4233741
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA946125A ZA946125B (en) | 1993-08-16 | 1994-08-15 | Novel macrolides and the use thereof |
Country Status (13)
Country | Link |
---|---|
US (1) | US5610178A (xx) |
EP (1) | EP0639644A1 (xx) |
JP (1) | JPH07157433A (xx) |
KR (1) | KR950005306A (xx) |
CN (1) | CN1106401A (xx) |
AU (1) | AU683067B2 (xx) |
CA (1) | CA2130044A1 (xx) |
FI (1) | FI943734A (xx) |
HU (1) | HUT70524A (xx) |
IL (1) | IL110659A0 (xx) |
NZ (1) | NZ264219A (xx) |
SG (1) | SG49853A1 (xx) |
ZA (1) | ZA946125B (xx) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2152765A1 (en) * | 1994-06-30 | 1995-12-31 | Jeroen Elisabeth-Joseph Knops | Methods for treating a physiological disorder associated with beta amyloid peptide |
US6605599B1 (en) * | 1997-07-08 | 2003-08-12 | Bristol-Myers Squibb Company | Epothilone derivatives |
US6852739B1 (en) | 1999-02-26 | 2005-02-08 | Nitromed Inc. | Methods using proton pump inhibitors and nitric oxide donors |
JP2002537336A (ja) * | 1999-02-26 | 2002-11-05 | ニトロメド インコーポレーテッド | ニトロソ化およびニトロシル化されたプロトンポンプ阻害剤、組成物および使用方法 |
AU4682700A (en) * | 1999-04-30 | 2000-11-17 | Research Corporation Technologies, Inc. | Bone targeting agents for osteoporosis |
DE10040052A1 (de) * | 2000-08-11 | 2002-03-07 | Univ Eberhard Karls | Verwendung von Protonenpumpen-Hemmern zur Behandlung von Entzündungen, insbesondere von Erkrankungen des Bewegungsapparates |
DE60330651D1 (en) | 2002-03-12 | 2010-02-04 | Bristol Myers Squibb Co | C3-cyanoepothilonderivate |
KR101285695B1 (ko) * | 2002-07-31 | 2013-07-12 | 에자이 알앤드디 매니지먼트 가부시키가이샤 | 신규한 생리 활성 물질 |
AU2003254282A1 (en) * | 2002-08-01 | 2004-02-23 | Nitromed, Inc. | Nitrosated proton pump inhibitors, compositions and methods of use |
US8463852B2 (en) * | 2006-10-06 | 2013-06-11 | Oracle International Corporation | Groupware portlets for integrating a portal with groupware systems |
MX2010008751A (es) * | 2008-02-08 | 2010-08-31 | Basilea Pharmaceutica Ag | Macrolidos para tratamiento de enfermedades mediadas a traves de inhibicion de pde. |
US20120225889A1 (en) * | 2009-11-17 | 2012-09-06 | Piramal Life Sciences Limited | Use of macrocyclic lactone derivatives for the treatment of inflammatory disorders |
EP4263516A1 (en) * | 2020-12-16 | 2023-10-25 | The Regents of The University of Michigan | Inhibitors of nef downmodulation |
WO2024073129A1 (en) * | 2022-09-30 | 2024-04-04 | Sherman David H | Novel plecomacrolide derivatives for mhc-i nef downmodulation |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE8903529D0 (sv) * | 1989-10-24 | 1989-10-24 | M Hersloef | Medical use |
JPH0559046A (ja) * | 1991-06-26 | 1993-03-09 | Ajinomoto Co Inc | 免疫調節剤 |
US5273979A (en) * | 1991-08-01 | 1993-12-28 | Merck & Co., Inc. | C-31 desmethyl FR-900520 cyclic hemiketal immunosuppressant agent |
-
1994
- 1994-08-08 SG SG9607607A patent/SG49853A1/en unknown
- 1994-08-08 EP EP94810460A patent/EP0639644A1/de not_active Withdrawn
- 1994-08-09 AU AU68999/94A patent/AU683067B2/en not_active Ceased
- 1994-08-09 US US08/287,984 patent/US5610178A/en not_active Expired - Fee Related
- 1994-08-11 NZ NZ264219A patent/NZ264219A/en unknown
- 1994-08-12 CA CA002130044A patent/CA2130044A1/en not_active Abandoned
- 1994-08-12 FI FI943734A patent/FI943734A/fi unknown
- 1994-08-13 KR KR1019940020017A patent/KR950005306A/ko not_active Application Discontinuation
- 1994-08-15 CN CN94108569A patent/CN1106401A/zh active Pending
- 1994-08-15 IL IL11065994A patent/IL110659A0/xx unknown
- 1994-08-15 HU HU9402361A patent/HUT70524A/hu unknown
- 1994-08-15 ZA ZA946125A patent/ZA946125B/xx unknown
- 1994-08-16 JP JP6192375A patent/JPH07157433A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
IL110659A0 (en) | 1994-11-11 |
CN1106401A (zh) | 1995-08-09 |
US5610178A (en) | 1997-03-11 |
KR950005306A (ko) | 1995-03-20 |
AU6899994A (en) | 1995-02-23 |
FI943734A (fi) | 1995-02-17 |
NZ264219A (en) | 1995-03-28 |
SG49853A1 (en) | 2001-07-24 |
HU9402361D0 (en) | 1994-10-28 |
FI943734A0 (fi) | 1994-08-12 |
AU683067B2 (en) | 1997-10-30 |
HUT70524A (en) | 1995-10-30 |
EP0639644A1 (de) | 1995-02-22 |
JPH07157433A (ja) | 1995-06-20 |
CA2130044A1 (en) | 1995-02-17 |
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