ZA941426B - Recombinant viruses and their use in gene therapy - Google Patents

Recombinant viruses and their use in gene therapy

Info

Publication number
ZA941426B
ZA941426B ZA941426A ZA941426A ZA941426B ZA 941426 B ZA941426 B ZA 941426B ZA 941426 A ZA941426 A ZA 941426A ZA 941426 A ZA941426 A ZA 941426A ZA 941426 B ZA941426 B ZA 941426B
Authority
ZA
South Africa
Prior art keywords
gene therapy
recombinant viruses
preparing
disclosed
eye diseases
Prior art date
Application number
ZA941426A
Inventor
Pascale Briand
Michel Perricaudet
Original Assignee
Rhone Poulenc Rorer Sa
Inst Nat Sante Rech Med
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Rorer Sa, Inst Nat Sante Rech Med filed Critical Rhone Poulenc Rorer Sa
Publication of ZA941426B publication Critical patent/ZA941426B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/10011—Adenoviridae
    • C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10341—Use of virus, viral particle or viral elements as a vector
    • C12N2710/10343—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Virology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

The use of defective recombinant adenoviruses containing an inserted gene for preparing a pharmaceutical useful for treating eye diseases is disclosed.
ZA941426A 1993-03-03 1994-03-01 Recombinant viruses and their use in gene therapy ZA941426B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9302438A FR2702152B1 (en) 1993-03-03 1993-03-03 Recombinant viruses and their use in gene therapy.

Publications (1)

Publication Number Publication Date
ZA941426B true ZA941426B (en) 1994-10-04

Family

ID=9444602

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA941426A ZA941426B (en) 1993-03-03 1994-03-01 Recombinant viruses and their use in gene therapy

Country Status (15)

Country Link
EP (1) EP0687184B1 (en)
JP (1) JP3835809B2 (en)
AT (1) ATE220923T1 (en)
AU (1) AU693782B2 (en)
CA (1) CA2154355A1 (en)
DE (1) DE69431046T2 (en)
DK (1) DK0687184T3 (en)
ES (1) ES2181710T3 (en)
FR (1) FR2702152B1 (en)
HU (1) HU218900B (en)
NO (1) NO319571B1 (en)
NZ (1) NZ262135A (en)
PT (1) PT687184E (en)
WO (1) WO1994020146A1 (en)
ZA (1) ZA941426B (en)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5792751A (en) * 1992-04-13 1998-08-11 Baylor College Of Medicine Tranformation of cells associated with fluid spaces
FR2717823B1 (en) * 1994-03-23 1996-04-26 Rhone Poulenc Rorer Sa Recombinant viruses, preparation and use in gene therapy.
FR2726575B1 (en) * 1994-11-09 1996-12-20 Rhone Poulenc Rorer Sa RECOMBINANT VIRUSES, PREPARATION AND USE IN GENE THERAPY
IL113052A0 (en) * 1994-03-23 1995-06-29 Rhone Poulenc Rorer Sa Recombinant viruses, their preparation and their use in gene therapy
FR2717824B1 (en) 1994-03-25 1996-04-26 Rhone Poulenc Rorer Sa Recombinant viruses, preparation and use in gene therapy.
FR2718150B1 (en) * 1994-03-29 1996-04-26 Rhone Poulenc Rorer Sa Recombinant viruses, preparation and use in gene therapy.
US5827702A (en) 1994-10-31 1998-10-27 Genentech, Inc. Ocular gene therapy
US6107027A (en) * 1994-12-14 2000-08-22 University Of Washington Ribozymes for treating hepatitis C
US6696423B1 (en) 1997-08-29 2004-02-24 Biogen, Inc. Methods and compositions for therapies using genes encoding secreted proteins such as interferon-beta
US6489305B1 (en) 1998-05-08 2002-12-03 Canji, Inc. Methods and compositions for the treatment of ocular diseases
ATE303820T1 (en) * 1999-12-30 2005-09-15 Aventis Pharma Sa USE OF A VECTOR ENCODING AN ANTI-ANGIogenic FACTOR FOR THE TREATMENT OF CORNEA VASCULARIZATION
FR2803207B1 (en) * 1999-12-30 2004-04-30 Aventis Pharma Sa USE OF A VECTOR COMPRISING A NUCLEIC ACID ENCODING AN ANTI-ANGIOGENIC FACTOR FOR THE TREATMENT OF CORNEAL NEOVASCULARIZATIONS
US6821775B1 (en) 2000-02-11 2004-11-23 Genvec, Inc. Viral vector encoding pigment epithelium-derived factor
US20030158112A1 (en) 2002-02-15 2003-08-21 Johns Hopkins University School Of Medicine Selective induction of apoptosis to treat ocular disease
BRPI0416920A (en) 2003-11-24 2007-01-23 Canji Inc dermal scar reduction
ES2407859T3 (en) 2004-09-13 2013-06-14 Genzyme Corporation Multimeric constructions.
HUE035554T2 (en) 2010-08-06 2018-05-02 Genzyme Corp Vegf antagonist compositions and uses thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1336678C (en) * 1988-09-13 1995-08-15 David L. Berliner Prophylaxis and treatment of nervous system diseases with melanin
EP0578776A4 (en) * 1991-04-05 1995-04-12 Edison Animal Biotech Center Retrovirus inhibition with antisense nucleic acids complementary to packaging sequences.

Also Published As

Publication number Publication date
AU6144494A (en) 1994-09-26
HU218900B (en) 2000-12-28
FR2702152B1 (en) 1995-05-24
ES2181710T3 (en) 2003-03-01
NO319571B1 (en) 2005-08-29
DE69431046T2 (en) 2003-02-13
FR2702152A1 (en) 1994-09-09
EP0687184A1 (en) 1995-12-20
CA2154355A1 (en) 1994-09-15
JPH08509208A (en) 1996-10-01
NO953329D0 (en) 1995-08-24
WO1994020146A1 (en) 1994-09-15
JP3835809B2 (en) 2006-10-18
DE69431046D1 (en) 2002-08-29
DK0687184T3 (en) 2002-10-28
AU693782B2 (en) 1998-07-09
PT687184E (en) 2002-12-31
HU9502573D0 (en) 1995-10-30
NZ262135A (en) 2000-12-22
HUT73215A (en) 1996-06-28
EP0687184B1 (en) 2002-07-24
ATE220923T1 (en) 2002-08-15
NO953329L (en) 1995-08-24

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