ZA941088B - Substituted ketophosphonates the processes for their preparation and pharmaceutical compositions containing them - Google Patents
Substituted ketophosphonates the processes for their preparation and pharmaceutical compositions containing themInfo
- Publication number
- ZA941088B ZA941088B ZA941088A ZA941088A ZA941088B ZA 941088 B ZA941088 B ZA 941088B ZA 941088 A ZA941088 A ZA 941088A ZA 941088 A ZA941088 A ZA 941088A ZA 941088 B ZA941088 B ZA 941088B
- Authority
- ZA
- South Africa
- Prior art keywords
- ketophosphonates
- substituted
- processes
- preparation
- pharmaceutical compositions
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6564—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms
- C07F9/6571—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and oxygen atoms as the only ring hetero atoms
- C07F9/657163—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and oxygen atoms as the only ring hetero atoms the ring phosphorus atom being bound to at least one carbon atom
- C07F9/657181—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and oxygen atoms as the only ring hetero atoms the ring phosphorus atom being bound to at least one carbon atom the ring phosphorus atom and, at least, one ring oxygen atom being part of a (thio)phosphonic acid derivative
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids RP(=O)(OH)2; Thiophosphonic acids, i.e. RP(=X)(XH)2 (X = S, Se)
- C07F9/40—Esters thereof
- C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
- C07F9/4006—Esters of acyclic acids which can have further substituents on alkyl
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids RP(=O)(OH)2; Thiophosphonic acids, i.e. RP(=X)(XH)2 (X = S, Se)
- C07F9/40—Esters thereof
- C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
- C07F9/4015—Esters of acyclic unsaturated acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids RP(=O)(OH)2; Thiophosphonic acids, i.e. RP(=X)(XH)2 (X = S, Se)
- C07F9/40—Esters thereof
- C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
- C07F9/4056—Esters of arylalkanephosphonic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids RP(=O)(OH)2; Thiophosphonic acids, i.e. RP(=X)(XH)2 (X = S, Se)
- C07F9/40—Esters thereof
- C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
- C07F9/4056—Esters of arylalkanephosphonic acids
- C07F9/4059—Compounds containing the structure (RY)2P(=X)-(CH2)n-C(=O)-(CH2)m-Ar, (X, Y = O, S, Se; n>=1, m>=0)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids RP(=O)(OH)2; Thiophosphonic acids, i.e. RP(=X)(XH)2 (X = S, Se)
- C07F9/44—Amides thereof
- C07F9/4403—Amides thereof the acid moiety containing a substituent or a structure which is considered as characteristic
- C07F9/4411—Amides of acyclic unsaturated acids
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH52193 | 1993-02-19 |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA941088B true ZA941088B (en) | 1995-09-27 |
Family
ID=4188911
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA941088A ZA941088B (en) | 1993-02-19 | 1994-02-17 | Substituted ketophosphonates the processes for their preparation and pharmaceutical compositions containing them |
Country Status (8)
Country | Link |
---|---|
EP (1) | EP0638084A1 (en) |
JP (1) | JPH07506121A (en) |
CN (1) | CN1106611A (en) |
AU (1) | AU6205294A (en) |
CA (1) | CA2118409A1 (en) |
MX (1) | MX9401295A (en) |
WO (1) | WO1994019358A1 (en) |
ZA (1) | ZA941088B (en) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE4433244A1 (en) * | 1994-09-19 | 1996-03-28 | Hoechst Ag | Aminomethylphosphonic and aminomethylphosphinic acid derivatives and their use for the treatment of degenerative joint diseases |
DE19502209A1 (en) * | 1995-01-25 | 1996-08-01 | Hoechst Ag | Phosphonoacetic acid derivatives and their use for the treatment of degenerative joint diseases |
JP3588734B2 (en) * | 1996-07-26 | 2004-11-17 | コニカミノルタホールディングス株式会社 | Electrophotographic photoreceptor |
WO2004026242A2 (en) * | 2002-09-19 | 2004-04-01 | Ilex Oncology Research, Sarl | Substituted ketophosphonate inhibitors of tumor cell proliferation |
WO2004026245A2 (en) * | 2002-09-19 | 2004-04-01 | Ilex Oncology Research, Sarl | Substituted phosphonate compounds having bone anabolic activity |
FR2876104B1 (en) | 2004-10-04 | 2007-02-23 | Centre Nat Rech Scient | FLUOROPHOSPHONOCINNAMIC COMPOUNDS, SYSTEM AND APLICATIONS |
GB0613518D0 (en) * | 2006-07-06 | 2006-08-16 | Phytopharm Plc | Chemical compounds |
BRPI0922089B1 (en) | 2008-11-13 | 2017-05-16 | Basf Se | use of compounds and cosmetic preparation |
EP2270021A1 (en) * | 2009-06-18 | 2011-01-05 | Centre National de la Recherche Scientifique | Phosphonates synthons for the synthesis of phosphonates derivatives showing better bioavailability |
CN109154016B (en) * | 2017-12-29 | 2021-11-16 | 邦泰生物工程(深圳)有限公司 | Method for preparing ursodeoxycholic acid by chemical-enzymatic method |
CN108794559A (en) * | 2018-07-31 | 2018-11-13 | 重庆波克底科技开发有限责任公司 | A method of using hyodesoxycholic acid as Material synthesis lithocholic acid |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2024030A1 (en) * | 1970-05-16 | 1971-12-02 | Deutsche Advance Produktion GmbH, 6141 Lautern | 2,6-dialkyl phenols |
JPS5921889B2 (en) * | 1975-06-02 | 1984-05-23 | 帝人株式会社 | Polyester manufacturing method |
JPS5782828A (en) * | 1980-11-11 | 1982-05-24 | Canon Inc | Heat developing photosensitive material |
EP0106799B1 (en) * | 1982-10-07 | 1986-03-19 | Ciba-Geigy Ag | Phenols and their preparation |
CH675422A5 (en) * | 1988-03-31 | 1990-09-28 | Symphar Sa | |
JPH0377894A (en) * | 1989-08-18 | 1991-04-03 | Toray Ind Inc | Methylene diphosphonic acid compound |
US5300687A (en) * | 1991-07-18 | 1994-04-05 | Ortho Pharmaceutical Corporation | Trifluoromethylbenzylphosphonates useful in treating osteoporosis |
-
1994
- 1994-02-17 ZA ZA941088A patent/ZA941088B/en unknown
- 1994-02-18 MX MX9401295A patent/MX9401295A/en unknown
- 1994-02-21 WO PCT/EP1994/000520 patent/WO1994019358A1/en not_active Application Discontinuation
- 1994-02-21 AU AU62052/94A patent/AU6205294A/en not_active Abandoned
- 1994-02-21 CN CN94190122A patent/CN1106611A/en active Pending
- 1994-02-21 JP JP6518667A patent/JPH07506121A/en active Pending
- 1994-02-21 EP EP94909033A patent/EP0638084A1/en not_active Withdrawn
- 1994-02-21 CA CA002118409A patent/CA2118409A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
CN1106611A (en) | 1995-08-09 |
WO1994019358A1 (en) | 1994-09-01 |
EP0638084A1 (en) | 1995-02-15 |
CA2118409A1 (en) | 1994-09-01 |
AU6205294A (en) | 1994-09-14 |
JPH07506121A (en) | 1995-07-06 |
MX9401295A (en) | 1994-08-31 |
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