ZA928730B - Therapeutic and diagnostic methods based on tissue-specific NT-3 expression and receptor binding. - Google Patents

Therapeutic and diagnostic methods based on tissue-specific NT-3 expression and receptor binding.

Info

Publication number
ZA928730B
ZA928730B ZA928730A ZA928730A ZA928730B ZA 928730 B ZA928730 B ZA 928730B ZA 928730 A ZA928730 A ZA 928730A ZA 928730 A ZA928730 A ZA 928730A ZA 928730 B ZA928730 B ZA 928730B
Authority
ZA
South Africa
Prior art keywords
therapeutic
tissue
expression
specific
receptor binding
Prior art date
Application number
ZA928730A
Other languages
English (en)
Inventor
C Anthony Altar
Peter Distefano
Stanley Wiegand
Nancy Ip
Carolyn Hyman
Roseann Ventimiglia
Ronald Lindsay
Original Assignee
Regeneron Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Regeneron Pharma filed Critical Regeneron Pharma
Publication of ZA928730B publication Critical patent/ZA928730B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/185—Nerve growth factor [NGF]; Brain derived neurotrophic factor [BDNF]; Ciliary neurotrophic factor [CNTF]; Glial derived neurotrophic factor [GDNF]; Neurotrophins, e.g. NT-3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Toxicology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
ZA928730A 1991-11-12 1992-11-12 Therapeutic and diagnostic methods based on tissue-specific NT-3 expression and receptor binding. ZA928730B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US79085791A 1991-11-12 1991-11-12

Publications (1)

Publication Number Publication Date
ZA928730B true ZA928730B (en) 1993-05-10

Family

ID=25151941

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA928730A ZA928730B (en) 1991-11-12 1992-11-12 Therapeutic and diagnostic methods based on tissue-specific NT-3 expression and receptor binding.

Country Status (6)

Country Link
CN (1) CN1073264A (xx)
AU (1) AU3130493A (xx)
IL (1) IL103730A0 (xx)
PT (1) PT101051A (xx)
WO (1) WO1993009798A1 (xx)
ZA (1) ZA928730B (xx)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2269075A1 (en) * 1996-10-16 1998-04-23 Regeneron Pharmaceuticals, Inc. Method of enhancing the delivery of growth factors
WO1998021245A1 (de) * 1996-11-08 1998-05-22 Roche Diagnostics Gmbh eOCHAFFINE ANTIKÖRPER GEGEN HUMAN-BDNF, VERFAHREN ZU IHRER HERSTELLUNG UND VERWENDUNG
EP1173768B1 (en) * 1999-05-03 2006-10-25 Evotec AG Methods of diagnosing, prognosing, monitoring the progression or evaluating of a treatment of depression on basis of increased cerebrospinal fluid levels of neurotrophin 3
EP1050758A1 (en) * 1999-05-03 2000-11-08 Evotec BioSystems AG Methods of diagnosing or treating neuropsychiatric diseases on basis of increased cerebrospinal fluid levels of neurotrophin 3
US6548062B2 (en) * 2000-02-29 2003-04-15 Cephalon, Inc. Method of treating cancer with anti-neurotrophin agents
CN110812532A (zh) * 2019-08-20 2020-02-21 中山大学 一种靶向促进皮质脊髓束连接以修复脊髓损伤的组织工程支架的构建方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4868107A (en) * 1986-11-18 1989-09-19 The United States Of America As Represented By The Department Of Health And Human Services Method for detecting antibodies against neuropeptides and drugs in human body fluid

Also Published As

Publication number Publication date
IL103730A0 (en) 1993-04-04
WO1993009798A1 (en) 1993-05-27
AU3130493A (en) 1993-06-15
PT101051A (pt) 1994-02-28
CN1073264A (zh) 1993-06-16

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