ZA914536B - 8-lower alkyl-5-cycloalkyl or 5-cycloakenyl substituted benzazepines and pharmaceutical compositions containing them - Google Patents

8-lower alkyl-5-cycloalkyl or 5-cycloakenyl substituted benzazepines and pharmaceutical compositions containing them

Info

Publication number
ZA914536B
ZA914536B ZA914536A ZA914536A ZA914536B ZA 914536 B ZA914536 B ZA 914536B ZA 914536 A ZA914536 A ZA 914536A ZA 914536 A ZA914536 A ZA 914536A ZA 914536 B ZA914536 B ZA 914536B
Authority
ZA
South Africa
Prior art keywords
cycloakenyl
cycloalkyl
lower alkyl
pharmaceutical compositions
compositions containing
Prior art date
Application number
ZA914536A
Inventor
Wei Kong Chang
Kong Chang Wei
Joseph A Kozlowski
A Kozlowski Joseph
Derek B Lowe
B Lowe Derek
Joel Gilbert Berger
Gilbert Berger Joel
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Publication of ZA914536B publication Critical patent/ZA914536B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/16—Benzazepines; Hydrogenated benzazepines
ZA914536A 1990-06-15 1991-06-13 8-lower alkyl-5-cycloalkyl or 5-cycloakenyl substituted benzazepines and pharmaceutical compositions containing them ZA914536B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US53896590A 1990-06-15 1990-06-15

Publications (1)

Publication Number Publication Date
ZA914536B true ZA914536B (en) 1992-03-25

Family

ID=24149189

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA914536A ZA914536B (en) 1990-06-15 1991-06-13 8-lower alkyl-5-cycloalkyl or 5-cycloakenyl substituted benzazepines and pharmaceutical compositions containing them

Country Status (6)

Country Link
AU (1) AU8201591A (en)
IE (1) IE912031A1 (en)
IL (1) IL98487A0 (en)
PT (1) PT97984A (en)
WO (1) WO1991019698A1 (en)
ZA (1) ZA914536B (en)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5241065A (en) * 1992-02-25 1993-08-31 Schering Corporation 2,3,4,5-tetrahydro-1h-3-benzazepines having anti-psychotic activity
US6953787B2 (en) 2002-04-12 2005-10-11 Arena Pharmaceuticals, Inc. 5HT2C receptor modulators
NZ540148A (en) 2002-12-20 2007-11-30 Glaxo Group Ltd Benzazepine derivatives for the treatment of neurological disorders
EA016558B1 (en) 2003-06-17 2012-05-30 Арена Фармасьютикалз, Инк. Benzazepine derivatives useful for the treatment of 5htreceptor associated diseases
HUE028976T2 (en) 2003-06-17 2017-02-28 Arena Pharm Inc 8-Chloro-1 -methyl-2,3,4,5-tetrahydro-1 H-3benzazapine Hydrochloride
US20080009478A1 (en) * 2003-10-22 2008-01-10 Arena Pharmaceuticals, Inc. Benzazepine Derivatives and Methods of Prophylaxis or Treatment of 5Ht2c Receptor Associated Diseases
JP5270167B2 (en) 2004-12-21 2013-08-21 アリーナ ファーマシューティカルズ， インコーポレイテッド Crystalline form of (R) -8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrochloride
CN102631349A (en) 2004-12-23 2012-08-15 艾尼纳制药公司 5ht2c receptor modulator compositions and methods of use
JP5199997B2 (en) 2006-04-03 2013-05-15 アリーナ ファーマシューティカルズ， インコーポレイテッド Process for preparing 8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine and related intermediates
CN101547892B (en) 2006-12-05 2014-08-20 艾尼纳制药公司 Processes for preparing (r)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine and intermediates thereof
JP5491421B2 (en) 2008-03-04 2014-05-14 アリーナ ファーマシューティカルズ， インコーポレイテッド Process for the preparation of intermediates related to the 5-HT2C agonist (R) -8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine
WO2010148207A2 (en) 2009-06-18 2010-12-23 Arena Pharmaceuticals, Inc. Processes for the preparation of 5-ht2c receptor agonists
WO2011153206A1 (en) 2010-06-02 2011-12-08 Arena Pharmaceuticals, Inc. Processes for the preparation of 5-ht2c receptor agonists
EP2611433A2 (en) 2010-09-01 2013-07-10 Arena Pharmaceuticals, Inc. Non-hygroscopic salts of 5-ht2c agonists
SG188362A1 (en) 2010-09-01 2013-04-30 Arena Pharm Inc Modified-release dosage forms of 5-ht2c agonists useful for weight management
US8999970B2 (en) 2010-09-01 2015-04-07 Arena Pharmaceuticals, Inc. Administration of an anti-obesity compound to individuals with renal impairment
SG10201506870PA (en) 2010-09-01 2015-10-29 Arena Pharm Inc Salts of lorcaserin with optically active acids
KR20150070249A (en) 2012-10-09 2015-06-24 아레나 파마슈티칼스, 인크. Method of weight management

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA882080B (en) * 1987-03-27 1989-04-26 Schering Corp Substituted benzazepines,their preparation and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
PT97984A (en) 1992-03-31
IL98487A0 (en) 1992-07-15
WO1991019698A1 (en) 1991-12-26
AU8201591A (en) 1992-01-07
IE912031A1 (en) 1991-12-18

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