ZA911538B - New benzimidazole derivatives,process for their production and their pharmaceutical use - Google Patents

New benzimidazole derivatives,process for their production and their pharmaceutical use

Info

Publication number
ZA911538B
ZA911538B ZA911538A ZA911538A ZA911538B ZA 911538 B ZA911538 B ZA 911538B ZA 911538 A ZA911538 A ZA 911538A ZA 911538 A ZA911538 A ZA 911538A ZA 911538 B ZA911538 B ZA 911538B
Authority
ZA
South Africa
Prior art keywords
production
pharmaceutical use
benzimidazole derivatives
new benzimidazole
new
Prior art date
Application number
ZA911538A
Inventor
Rudolf Albrecht
Albrecht Rudolf
Manfred Lehmann
Lehmann Manfred
Klaus Schollkopf
Schollkopf Klaus
Rolf Beckmann
Beckmann Rolf
Hermann Graf
Graf Hermann
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of ZA911538B publication Critical patent/ZA911538B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • C07D235/08—Radicals containing only hydrogen and carbon atoms
ZA911538A 1990-03-01 1991-03-01 New benzimidazole derivatives,process for their production and their pharmaceutical use ZA911538B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4006693A DE4006693A1 (en) 1990-03-01 1990-03-01 NEW BENZIMIDAZOLE DERIVATIVES, METHOD FOR THEIR PRODUCTION AND THEIR PHARMACEUTICAL USE

Publications (1)

Publication Number Publication Date
ZA911538B true ZA911538B (en) 1992-02-26

Family

ID=6401349

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA911538A ZA911538B (en) 1990-03-01 1991-03-01 New benzimidazole derivatives,process for their production and their pharmaceutical use

Country Status (6)

Country Link
AU (1) AU7257891A (en)
DE (1) DE4006693A1 (en)
IE (1) IE910686A1 (en)
PT (1) PT96922A (en)
WO (1) WO1991013063A1 (en)
ZA (1) ZA911538B (en)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU653524B2 (en) * 1990-06-08 1994-10-06 Roussel-Uclaf New imidazole derivatives, their preparation process, the new intermediates obtained, their use as medicaments and the pharmaceutical compositions containing them
US5317023A (en) * 1991-05-16 1994-05-31 Glaxo Group Limited Benzofuran derivatives
GB9218449D0 (en) 1992-08-29 1992-10-14 Boots Co Plc Therapeutic agents
SE9903028D0 (en) 1999-08-27 1999-08-27 Astra Ab New use
US8969514B2 (en) 2007-06-04 2015-03-03 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
US7879802B2 (en) 2007-06-04 2011-02-01 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
EP3239170B1 (en) 2008-06-04 2019-03-20 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
US9616097B2 (en) 2010-09-15 2017-04-11 Synergy Pharmaceuticals, Inc. Formulations of guanylate cyclase C agonists and methods of use
US9708367B2 (en) 2013-03-15 2017-07-18 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase and their uses
CA2905435A1 (en) 2013-03-15 2014-09-25 Synergy Pharmaceuticals Inc. Compositions useful for the treatment of gastrointestinal disorders
JP6606491B2 (en) 2013-06-05 2019-11-13 シナジー ファーマシューティカルズ インコーポレイテッド Ultra high purity agonist of guanylate cyclase C, method for producing and using the same
US9828348B2 (en) 2013-11-08 2017-11-28 Purdue Pharma L.P. Benzimidazole derivatives and use thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4880804A (en) * 1988-01-07 1989-11-14 E. I. Du Pont De Nemours And Company Angiotensin II receptor blocking benzimidazoles
DE3928177A1 (en) * 1989-04-08 1991-02-28 Thomae Gmbh Dr K BENZIMIDAZOLE, MEDICAMENTS CONTAINING THESE COMPOUNDS AND METHOD FOR THE PRODUCTION THEREOF
CA2016710A1 (en) * 1989-05-15 1990-11-15 Prasun K. Chakravarty Substituted benzimidazoles as angiotensin ii antagonists
GB8911854D0 (en) * 1989-05-23 1989-07-12 Ici Plc Heterocyclic compounds
IE70593B1 (en) * 1989-09-29 1996-12-11 Eisai Co Ltd Biphenylmethane derivative the use of it and pharmacological compositions containing same

Also Published As

Publication number Publication date
AU7257891A (en) 1991-09-18
PT96922A (en) 1991-10-31
DE4006693A1 (en) 1991-09-05
WO1991013063A1 (en) 1991-09-05
IE910686A1 (en) 1991-09-11

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