ZA896150B - The use of alpha-amino boronic acid derivatives for the prophylaxis and treatment of virus diseases - Google Patents

The use of alpha-amino boronic acid derivatives for the prophylaxis and treatment of virus diseases

Info

Publication number
ZA896150B
ZA896150B ZA896150A ZA896150A ZA896150B ZA 896150 B ZA896150 B ZA 896150B ZA 896150 A ZA896150 A ZA 896150A ZA 896150 A ZA896150 A ZA 896150A ZA 896150 B ZA896150 B ZA 896150B
Authority
ZA
South Africa
Prior art keywords
prophylaxis
alpha
treatment
acid derivatives
boronic acid
Prior art date
Application number
ZA896150A
Inventor
Karin Molling
Molling Karin
Heinz-Werner Kleemann
Kleemann Heinz-Werner
Hansjorg Urbach
Urbach Hansjorg
Wolfgang Konig
Konig Wolfgang
Dieter Ruppert
Ruppert Dieter
Irvin Winkler
Winkler Irvin
Arnold Paessens
Paessens Arnold
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of ZA896150B publication Critical patent/ZA896150B/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55—Protease inhibitors
    • A61K38/553—Renin inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/69—Boron compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Virology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
ZA896150A 1988-08-12 1989-08-11 The use of alpha-amino boronic acid derivatives for the prophylaxis and treatment of virus diseases ZA896150B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3827340A DE3827340A1 (en) 1988-08-12 1988-08-12 USE OF (ALPHA) -AMINOBORONIC ACID DERIVATIVES FOR THE PROPHYLAXIS AND TREATMENT OF VIRUS DISEASES

Publications (1)

Publication Number Publication Date
ZA896150B true ZA896150B (en) 1991-01-30

Family

ID=6360676

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA896150A ZA896150B (en) 1988-08-12 1989-08-11 The use of alpha-amino boronic acid derivatives for the prophylaxis and treatment of virus diseases

Country Status (10)

Country Link
EP (1) EP0354522A1 (en)
JP (1) JPH0291023A (en)
KR (1) KR900002766A (en)
AU (1) AU3951389A (en)
DE (1) DE3827340A1 (en)
DK (1) DK395789A (en)
IL (1) IL91276A0 (en)
NO (1) NO893240L (en)
PT (1) PT91426A (en)
ZA (1) ZA896150B (en)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5142056A (en) * 1989-05-23 1992-08-25 Abbott Laboratories Retroviral protease inhibiting compounds
EP0315574A3 (en) * 1987-11-05 1990-08-22 Hoechst Aktiengesellschaft Renin inhibitors
US4983589A (en) * 1989-12-14 1991-01-08 Chevron Research And Technology Company Fungicidal imidazole diphenylaliphaticboranes and derivatives thereof
GB9017694D0 (en) * 1990-08-13 1990-09-26 Sandoz Ltd Improvements in or relating to organic chemistry
GB9024775D0 (en) * 1990-11-14 1991-01-02 Axis Research Chemical compounds
US5554728A (en) * 1991-07-23 1996-09-10 Nexstar Pharmaceuticals, Inc. Lipid conjugates of therapeutic peptides and protease inhibitors
DE4126485A1 (en) * 1991-08-10 1993-02-11 Bayer Ag TRIFLUOROMETHYL-CONTAINING PSEUDOPEPTIDE
US5693617A (en) * 1994-03-15 1997-12-02 Proscript, Inc. Inhibitors of the 26s proteolytic complex and the 20s proteasome contained therein
US6083903A (en) 1994-10-28 2000-07-04 Leukosite, Inc. Boronic ester and acid compounds, synthesis and uses
DE4441483C1 (en) * 1994-11-22 1996-04-04 Gsf Forschungszentrum Umwelt Use of bio-assimilated boron cpds.
US7223745B2 (en) 2003-08-14 2007-05-29 Cephalon, Inc. Proteasome inhibitors and methods of using the same
US7576206B2 (en) 2003-08-14 2009-08-18 Cephalon, Inc. Proteasome inhibitors and methods of using the same
US7468383B2 (en) 2005-02-11 2008-12-23 Cephalon, Inc. Proteasome inhibitors and methods of using the same
US7442830B1 (en) 2007-08-06 2008-10-28 Millenium Pharmaceuticals, Inc. Proteasome inhibitors
US7838673B2 (en) 2007-10-16 2010-11-23 Millennium Pharmaceuticals, Inc. Proteasome inhibitors
EA201500431A1 (en) 2008-06-17 2015-11-30 Милленниум Фармасьютикалз, Инк. COMPOUNDS OF BONONATE AIR AND ITS PHARMACEUTICAL COMPOSITIONS
AR075090A1 (en) 2008-09-29 2011-03-09 Millennium Pharm Inc ACID DERIVATIVES 1-AMINO-2-CYCLLOBUTILETILBORONICO PROTEOSOMA INHIBITORS, USEFUL AS ANTI-BANKER AGENTS, AND PHARMACEUTICAL COMPOSITIONS THAT UNDERSTAND THEM.
JP5783659B2 (en) 2009-12-22 2015-09-24 セファロン、インク． Proteasome inhibitors and methods for their preparation, purification and use
JP6042724B2 (en) * 2010-03-01 2016-12-14 オニキス セラピューティクス， インク．Ｏｎｙｘ Ｔｈｅｒａｐｅｕｔｉｃｓ， Ｉｎｃ． Compounds for immunoproteasome inhibition
NZ602622A (en) 2010-03-31 2015-01-30 Millennium Pharm Inc Derivatives of 1-amino-2-cyclopropylethylboronic acid
CN103483363B (en) * 2012-06-13 2016-12-21 上海赛迦化工产品有限公司 Multifarious chiral aminoboronic acid and its preparation method and application
CN103408572B (en) * 2013-07-12 2015-12-02 上海工程技术大学 Chiral aminoboronic acid derivative and its preparation method and application
CN105418663B (en) * 2013-07-12 2017-12-22 上海工程技术大学 A kind of chiral boronic acid derivatives and its preparation method and application
US20150335668A1 (en) 2014-05-20 2015-11-26 Millennium Pharmaceuticals, Inc. Method for cancer therapy
EA201990069A1 (en) 2016-06-21 2019-06-28 ОРИОН ОФТАЛМОЛОДЖИ ЭлЭлСи DERIVATIVES OF HETEROCYCLIC PROLINAMIDE
US10526315B2 (en) 2016-06-21 2020-01-07 Orion Ophthalmology LLC Carbocyclic prolinamide derivatives

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4499082A (en) * 1983-12-05 1985-02-12 E. I. Du Pont De Nemours And Company α-Aminoboronic acid peptides
US4537773A (en) * 1983-12-05 1985-08-27 E. I. Du Pont De Nemours And Company α-Aminoboronic acid derivatives
US5187157A (en) * 1987-06-05 1993-02-16 Du Pont Merck Pharmaceutical Company Peptide boronic acid inhibitors of trypsin-like proteases
EP0315574A3 (en) * 1987-11-05 1990-08-22 Hoechst Aktiengesellschaft Renin inhibitors

Also Published As

Publication number Publication date
NO893240D0 (en) 1989-08-11
PT91426A (en) 1990-03-08
DK395789D0 (en) 1989-08-11
KR900002766A (en) 1990-03-31
AU3951389A (en) 1990-03-29
JPH0291023A (en) 1990-03-30
DK395789A (en) 1990-02-13
IL91276A0 (en) 1990-03-19
DE3827340A1 (en) 1990-02-15
EP0354522A1 (en) 1990-02-14
NO893240L (en) 1990-03-27

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