ZA892325B - Protease-deficient gram-positive bacteria and their use as host organisms for the production of recombinant products - Google Patents
Protease-deficient gram-positive bacteria and their use as host organisms for the production of recombinant productsInfo
- Publication number
- ZA892325B ZA892325B ZA892325A ZA892325A ZA892325B ZA 892325 B ZA892325 B ZA 892325B ZA 892325 A ZA892325 A ZA 892325A ZA 892325 A ZA892325 A ZA 892325A ZA 892325 B ZA892325 B ZA 892325B
- Authority
- ZA
- South Africa
- Prior art keywords
- deficient
- protease
- gram
- production
- positive bacteria
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/52—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
- C12N9/54—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea bacteria being Bacillus
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
- C12N15/75—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Bacillus
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
- C12Q1/37—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving peptidase or proteinase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
- C12Q1/689—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/195—Assays involving biological materials from specific organisms or of a specific nature from bacteria
- G01N2333/32—Assays involving biological materials from specific organisms or of a specific nature from bacteria from Bacillus (G)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/914—Hydrolases (3)
- G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
- G01N2333/95—Proteinases, i.e. endopeptidases (3.4.21-3.4.99)
- G01N2333/964—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue
- G01N2333/96425—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals
- G01N2333/96427—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general
- G01N2333/9643—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general with EC number
- G01N2333/96466—Cysteine endopeptidases (3.4.22)
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Biomedical Technology (AREA)
- Biophysics (AREA)
- Immunology (AREA)
- Plant Pathology (AREA)
- Medicinal Chemistry (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US19048388A | 1988-05-05 | 1988-05-05 |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA892325B true ZA892325B (en) | 1990-03-28 |
Family
ID=22701537
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA892325A ZA892325B (en) | 1988-05-05 | 1989-03-29 | Protease-deficient gram-positive bacteria and their use as host organisms for the production of recombinant products |
Country Status (11)
Country | Link |
---|---|
EP (1) | EP0370103A4 (en) |
JP (1) | JPH03500606A (en) |
AU (1) | AU622916B2 (en) |
DK (1) | DK1590A (en) |
FI (1) | FI900045A0 (en) |
HU (1) | HUT53154A (en) |
IL (1) | IL89767A0 (en) |
NZ (1) | NZ228424A (en) |
PT (1) | PT90463A (en) |
WO (1) | WO1989010976A1 (en) |
ZA (1) | ZA892325B (en) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5143846A (en) * | 1988-03-17 | 1992-09-01 | The General Hospital Corporation | Protease deficient bacterial hosts |
US5294542A (en) * | 1991-03-19 | 1994-03-15 | Omnigene, Inc. | Residual protease-III |
IL102259A0 (en) * | 1991-07-01 | 1993-01-14 | Amgen Inc | Isolation and characterization of a protease from streptomyces lividans |
US5288931A (en) * | 1991-12-06 | 1994-02-22 | Genentech, Inc. | Method for refolding insoluble, misfolded insulin-like growth factor-I into an active conformation |
AU7788194A (en) | 1993-10-05 | 1995-05-01 | Medeva Holdings B.V. | Vaccine compositions |
GB9324529D0 (en) * | 1993-11-30 | 1994-01-19 | Univ Singapore | Biological control agents |
DE4425645A1 (en) * | 1994-07-20 | 1996-02-22 | Mueller Karl & Co Kg | New lysostaphin gene with deletion in pro-segment repeat region |
CA2296708A1 (en) * | 1997-07-15 | 1999-01-28 | Genencor International, Inc. | Proteases from gram-positive organisms |
US6762039B2 (en) * | 1997-07-15 | 2004-07-13 | Genencor International, Inc. | Bacillus subtillis with an inactivated cysteine protease-1 |
US6599731B1 (en) | 1997-12-30 | 2003-07-29 | Genencor International, Inc. | Proteases from gram positive organisms |
GB9727470D0 (en) | 1997-12-30 | 1998-02-25 | Genencor Int Bv | Proteases from gram positive organisms |
US6465186B1 (en) | 1997-12-30 | 2002-10-15 | Genecor International, Inc. | Proteases from gram positive organisms |
US6528255B1 (en) | 1997-12-30 | 2003-03-04 | Genencor International, Inc. | Proteases from gram positive organisms |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4931390A (en) * | 1986-04-16 | 1990-06-05 | Public Health Research Institute Of The City Of New York, Inc. | Expression of the cloned lysostaphin gene |
JP3026567B2 (en) * | 1987-02-27 | 2000-03-27 | ジェネンコー インターナショナル インコーポレイテッド | Molecular cloning and expression of genes encoding proteolytic enzymes |
-
1989
- 1989-03-14 WO PCT/US1989/001056 patent/WO1989010976A1/en not_active Application Discontinuation
- 1989-03-14 HU HU894054A patent/HUT53154A/en unknown
- 1989-03-14 EP EP19890906977 patent/EP0370103A4/en not_active Withdrawn
- 1989-03-14 JP JP1506242A patent/JPH03500606A/en active Pending
- 1989-03-14 AU AU37651/89A patent/AU622916B2/en not_active Ceased
- 1989-03-21 NZ NZ228424A patent/NZ228424A/en unknown
- 1989-03-28 IL IL89767A patent/IL89767A0/en unknown
- 1989-03-29 ZA ZA892325A patent/ZA892325B/en unknown
- 1989-05-04 PT PT90463A patent/PT90463A/en not_active Application Discontinuation
-
1990
- 1990-01-04 DK DK001590A patent/DK1590A/en not_active Application Discontinuation
- 1990-01-04 FI FI900045A patent/FI900045A0/en not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
NZ228424A (en) | 1992-06-25 |
HU894054D0 (en) | 1990-07-28 |
FI900045A (en) | 1990-01-04 |
PT90463A (en) | 1989-11-30 |
DK1590A (en) | 1990-02-05 |
FI900045A0 (en) | 1990-01-04 |
WO1989010976A1 (en) | 1989-11-16 |
IL89767A0 (en) | 1989-09-28 |
EP0370103A4 (en) | 1991-11-27 |
HUT53154A (en) | 1990-09-28 |
DK1590D0 (en) | 1990-01-04 |
EP0370103A1 (en) | 1990-05-30 |
AU622916B2 (en) | 1992-04-30 |
JPH03500606A (en) | 1991-02-14 |
AU3765189A (en) | 1989-11-29 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
HUT64764A (en) | Carbapenem-derivatives with antibiotic effect and medical preparatives containing them and process for the production thereof | |
AU2365388A (en) | Abrasive products | |
AU1145688A (en) | Abrasive product | |
AU616702B2 (en) | Disposable products | |
AU8267787A (en) | Protein product | |
HU912263D0 (en) | Process for the production of 5-alkyl-kynolone -carbonic acids, and antibacterial substances and fodder additives containing them | |
AU2094588A (en) | Fitted bed sheets | |
AU7687987A (en) | Starch-free yoghurt product | |
ZA892325B (en) | Protease-deficient gram-positive bacteria and their use as host organisms for the production of recombinant products | |
AU1853688A (en) | Control of bacteria | |
GB8700354D0 (en) | Culture of micro-organisms | |
AU1092288A (en) | Device permitting the prolonged storage of nutrient products | |
AU1171692A (en) | Method and container for the conservation of animal organism | |
AU3300789A (en) | Floor treatment product | |
AU6003886A (en) | Fitted bedding article | |
EP0292808A3 (en) | Substituted vinyl cephalosporins, process for their preparation and their use as medicines | |
AU7897087A (en) | Genetic transformation of gram-positive lactic acid-producing bacteria | |
AU1570588A (en) | New intermediate products and process | |
ZA882517B (en) | Organic compounds and their use as pharmaceuticals | |
AU5381890A (en) | Interferon for the use in the prevention or treatment of swine pneumonia or related bacterial diseases | |
HUT65566A (en) | Antibiotic ab-041 and the process for its production | |
EP0211490A3 (en) | Antibiotics of the vancomycin-class | |
GB2183665B (en) | Bacterial process for the production of dispersants | |
AP9000186A0 (en) | Bacterial strains and their application for the protection of cultures | |
GB8627774D0 (en) | Differentiation of lactobacillus from streptococcos organisms |