ZA878083B - Process for 2-(1-pentyl-3-guanidino)-4-(2-methyl-4-imidazolyl)thiazole and the crystalline dihydrochloride trihydrate thereof - Google Patents
Process for 2-(1-pentyl-3-guanidino)-4-(2-methyl-4-imidazolyl)thiazole and the crystalline dihydrochloride trihydrate thereofInfo
- Publication number
- ZA878083B ZA878083B ZA878083A ZA878083A ZA878083B ZA 878083 B ZA878083 B ZA 878083B ZA 878083 A ZA878083 A ZA 878083A ZA 878083 A ZA878083 A ZA 878083A ZA 878083 B ZA878083 B ZA 878083B
- Authority
- ZA
- South Africa
- Prior art keywords
- guanidino
- thiazole
- imidazolyl
- pentyl
- methyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C335/00—Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C335/04—Derivatives of thiourea
- C07C335/24—Derivatives of thiourea containing any of the groups, X being a hetero atom, Y being any atom
- C07C335/28—Y being a hetero atom, e.g. thiobiuret
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/US1986/002307 WO1988003140A1 (en) | 1986-10-29 | 1986-10-29 | Crystalline 2-(1-pentyl-3-guanidino)-4-(2-methyl-4-imidazolyl)thiazole dihydrochloride trihydrate |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA878083B true ZA878083B (en) | 1989-06-28 |
Family
ID=22195693
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA878083A ZA878083B (en) | 1986-10-29 | 1987-10-28 | Process for 2-(1-pentyl-3-guanidino)-4-(2-methyl-4-imidazolyl)thiazole and the crystalline dihydrochloride trihydrate thereof |
Country Status (11)
Country | Link |
---|---|
US (1) | US4997949A (no) |
JP (1) | JPS63122680A (no) |
AU (1) | AU579775B2 (no) |
CA (1) | CA1313378C (no) |
DD (2) | DD272851A5 (no) |
FI (1) | FI89918C (no) |
NO (1) | NO170417C (no) |
PH (1) | PH23922A (no) |
RU (1) | RU1779252C (no) |
WO (1) | WO1988003140A1 (no) |
ZA (1) | ZA878083B (no) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5387597A (en) * | 1991-02-25 | 1995-02-07 | Pfizer Inc. | Hemiphosphate hemihydrate of 2-(1-pentyl-3-guanidino)-4-(2-methyl-4-imidazolyl)thiazole |
NO329085B1 (no) * | 2008-01-31 | 2010-08-16 | Sorbwater Technology As | Fremgangsmate og apparat for separasjon av fluidfaser, samt anvendelser derav |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IN163170B (no) * | 1980-10-14 | 1988-08-20 | Pfizer | |
US4560690A (en) * | 1984-04-30 | 1985-12-24 | Pfizer Inc. | 2-(N-substituted guanidino)-4-hetero-arylthiazole antiulcer agents |
US4632993A (en) * | 1984-10-11 | 1986-12-30 | Pfizer Inc. | Process for making 2-guanidino-4-(2-methyl-4-imidazolyl) thiazole dihydrobromide |
JPS6191122A (ja) * | 1984-10-11 | 1986-05-09 | フアイザー・インコーポレーテツド | 2―グアニジノ―4―(2―メチル―4―イミダゾリル)チアゾール類からなる慢性関節リウマチ治療用組成物 |
-
1986
- 1986-10-29 US US07/365,155 patent/US4997949A/en not_active Expired - Lifetime
- 1986-10-29 WO PCT/US1986/002307 patent/WO1988003140A1/en active IP Right Grant
-
1987
- 1987-10-27 CA CA000550298A patent/CA1313378C/en not_active Expired - Fee Related
- 1987-10-27 PH PH35990A patent/PH23922A/en unknown
- 1987-10-27 DD DD87318777A patent/DD272851A5/de not_active IP Right Cessation
- 1987-10-27 DD DD87308315A patent/DD262659A5/de not_active IP Right Cessation
- 1987-10-28 ZA ZA878083A patent/ZA878083B/xx unknown
- 1987-10-28 AU AU80428/87A patent/AU579775B2/en not_active Ceased
- 1987-10-29 JP JP62274631A patent/JPS63122680A/ja active Granted
-
1988
- 1988-06-28 NO NO88882861A patent/NO170417C/no unknown
-
1989
- 1989-04-24 RU SU894613898A patent/RU1779252C/ru active
- 1989-04-28 FI FI892034A patent/FI89918C/fi not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
DD272851A5 (de) | 1989-10-25 |
NO170417B (no) | 1992-07-06 |
DD262659A5 (de) | 1988-12-07 |
AU8042887A (en) | 1988-05-05 |
JPS63122680A (ja) | 1988-05-26 |
AU579775B2 (en) | 1988-12-08 |
FI89918C (fi) | 1993-12-10 |
FI892034A (fi) | 1989-04-28 |
NO882861D0 (no) | 1988-06-28 |
JPH0513952B2 (no) | 1993-02-23 |
PH23922A (en) | 1990-01-23 |
WO1988003140A1 (en) | 1988-05-05 |
NO170417C (no) | 1992-10-14 |
FI892034A0 (fi) | 1989-04-28 |
FI89918B (fi) | 1993-08-31 |
US4997949A (en) | 1991-03-05 |
NO882861L (no) | 1988-06-28 |
RU1779252C (ru) | 1992-11-30 |
CA1313378C (en) | 1993-02-02 |
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