ZA868234B - Dopamine-beta-hydroxylase inhibitors - Google Patents

Dopamine-beta-hydroxylase inhibitors

Info

Publication number
ZA868234B
ZA868234B ZA868234A ZA868234A ZA868234B ZA 868234 B ZA868234 B ZA 868234B ZA 868234 A ZA868234 A ZA 868234A ZA 868234 A ZA868234 A ZA 868234A ZA 868234 B ZA868234 B ZA 868234B
Authority
ZA
South Africa
Prior art keywords
dopamine
beta
hydroxylase inhibitors
hydroxylase
inhibitors
Prior art date
Application number
ZA868234A
Other languages
English (en)
Inventor
Joseph Alan Finkelstein
Carl Kaiser
Lawrence Ivan Kruse
Original Assignee
Smithkline Beckman Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beckman Corp filed Critical Smithkline Beckman Corp
Publication of ZA868234B publication Critical patent/ZA868234B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C07D249/10—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D249/12—Oxygen or sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
ZA868234A 1985-10-31 1986-10-29 Dopamine-beta-hydroxylase inhibitors ZA868234B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/793,513 US4628059A (en) 1985-10-31 1985-10-31 Dopamine-β-hydroxylase inhibitors

Publications (1)

Publication Number Publication Date
ZA868234B true ZA868234B (en) 1987-12-30

Family

ID=25160085

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA868234A ZA868234B (en) 1985-10-31 1986-10-29 Dopamine-beta-hydroxylase inhibitors

Country Status (7)

Country Link
US (1) US4628059A (ja)
EP (1) EP0225718A3 (ja)
JP (1) JPS62108869A (ja)
AU (1) AU597600B2 (ja)
DK (1) DK515686A (ja)
PT (1) PT83626B (ja)
ZA (1) ZA868234B (ja)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PH23506A (en) * 1986-05-23 1989-08-16 Smithkline Beckman Corp 1-aralkyl-substituted-1,2,4,-triazole-5-thiols as dopamine- -hydroxylase inhibitors
US4761415A (en) * 1986-08-28 1988-08-02 Smithkline Beckman Corporation Dopamine-β-hydroxylase inhibitors
AU2948189A (en) * 1987-12-31 1989-08-01 Smithkline Beckman Corporation 4-aralkyl-5-substituted-1,2,4-triazole-5-thiols
MX2020005864A (es) 2017-12-04 2020-09-09 BIAL PORTELA & Cª S A Inhibidores de dopamina-b-hidroxilasa.

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4271308A (en) * 1968-09-04 1981-06-02 Rohm And Haas Company 4-alkyl-1,2,4-4H-triazole derivatives
US4120864A (en) * 1970-08-26 1978-10-17 Rohm And Haas Company 1,2,4-4H-triazole derivatives
US4082762A (en) * 1975-08-25 1978-04-04 Eli Lilly And Company 4-(2-halophenyl)-1,2,4-triazole-3-thiol compounds
PH23506A (en) * 1986-05-23 1989-08-16 Smithkline Beckman Corp 1-aralkyl-substituted-1,2,4,-triazole-5-thiols as dopamine- -hydroxylase inhibitors
US4761415A (en) * 1986-08-28 1988-08-02 Smithkline Beckman Corporation Dopamine-β-hydroxylase inhibitors

Also Published As

Publication number Publication date
JPS62108869A (ja) 1987-05-20
US4628059A (en) 1986-12-09
AU597600B2 (en) 1990-06-07
EP0225718A2 (en) 1987-06-16
PT83626B (en) 1988-11-21
DK515686A (da) 1987-05-01
EP0225718A3 (en) 1988-03-30
PT83626A (en) 1986-11-01
DK515686D0 (da) 1986-10-28
AU6463886A (en) 1987-05-07

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