ZA862929B - Process for preparing(z)-1-phenyl-1-diethylaminocarbonyl-2-aminomethyl-cyclopropane hydrochloride - Google Patents

Process for preparing(z)-1-phenyl-1-diethylaminocarbonyl-2-aminomethyl-cyclopropane hydrochloride

Info

Publication number: ZA862929B
Authority: ZA; South Africa
Prior art keywords: diethylaminocarbonyl; aminomethyl; phenyl; preparing; cyclopropane hydrochloride
Prior art date: 1985-04-25

Application number

ZA862929A

Inventor

Bernard Bonnaud

Henri Cousse

Gilbert Mouzin

Jean-Francois Patoiseau

Original Assignee

Pf Medicament

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1985-04-25

Filing date

1986-04-18

Publication date

1986-12-30

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9318686&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ZA862929(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1986-04-18 Application filed by Pf Medicament filed Critical Pf Medicament

1986-12-30 Publication of ZA862929B publication Critical patent/ZA862929B/en

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/12—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by halogen atoms or by nitro or nitroso groups
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/24—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a ring other than a six-membered aromatic ring of the carbon skeleton

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Indole Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Furan Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

ZA862929A 1985-04-25 1986-04-18 Process for preparing(z)-1-phenyl-1-diethylaminocarbonyl-2-aminomethyl-cyclopropane hydrochloride ZA862929B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
FR8506335A FR2581059B1 (en)	1985-04-25	1985-04-25	PROCESS FOR THE PREPARATION OF PHENYL-1 HYDROCHLORIDE DIETHYL AMINO CARBONYL-1 AMINOMETHYL-2 CYCLOPROPANE (Z)

Publications (1)

Publication Number	Publication Date
ZA862929B true ZA862929B (en)	1986-12-30

Family

ID=9318686

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA862929A ZA862929B (en)	1985-04-25	1986-04-18	Process for preparing(z)-1-phenyl-1-diethylaminocarbonyl-2-aminomethyl-cyclopropane hydrochloride

Country Status (23)

Country	Link
EP (1)	EP0200638B1 (en)
JP (1)	JPS61251650A (en)
KR (1)	KR940006764B1 (en)
AR (1)	AR240695A1 (en)
AT (1)	ATE42273T1 (en)
AU (1)	AU587613B2 (en)
CA (1)	CA1266486A (en)
DE (1)	DE3662877D1 (en)
DK (1)	DK170888B1 (en)
ES (1)	ES8704449A1 (en)
FI (1)	FI87196C (en)
FR (1)	FR2581059B1 (en)
GE (1)	GEP19970789B (en)
GR (1)	GR860980B (en)
HU (1)	HU195182B (en)
IE (1)	IE59015B1 (en)
MX (1)	MX162896B (en)
NO (1)	NO165143C (en)
OA (1)	OA08241A (en)
PT (1)	PT82461B (en)
SU (1)	SU1443797A3 (en)
YU (1)	YU44915B (en)
ZA (1)	ZA862929B (en)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2640972B1 (en) *	1988-12-28	1991-04-19	Pf Medicament
US5621142A (en) *	1994-02-22	1997-04-15	Asahi Kasei Kogyo Kabushiki Kaisha	Aminoalkylcyclopropane derivatives
FR2752732B1 (en) *	1996-08-28	1998-11-20	Pf Medicament	EXTENDED RELEASE GALENIC FORM OF MILNACIPRAN
JP4418717B2 (en)	2004-06-24	2010-02-24	住友化学株式会社	Process for producing (Z) -1-phenyl-1-diethylaminocarbonyl-2-aminomethylcyclopropane hydrochloride
JP4828863B2 (en)	2005-01-28	2011-11-30	住友化学株式会社	Process for producing (Z) -1-phenyl-1- (N, N-diethylaminocarbonyl) -2-phthalimidomethylcyclopropane
US8309128B2 (en)	2005-06-10	2012-11-13	Pierre Fabre Medicament	Stabilized milnacipran formulation
KR100772244B1 (en) *	2005-07-20	2007-11-01	안국약품 주식회사	Method for the preparation of milnacipran hydrogen chloride salt
JP5338035B2 (en) *	2006-04-17	2013-11-13	住友化学株式会社	Process for producing polycyclic lactams
US20090118519A1 (en) *	2006-04-17	2009-05-07	Sumitomo Chemical Company, Limited	Production Method of Polycyclic Lactams
EP2114868A2 (en) *	2007-02-28	2009-11-11	Ranbaxy Laboratories Limited	Novel polymorphic forms of milnacipran hydrochloride
FR2941454B1 (en)	2009-01-29	2011-04-01	Pf Medicament	PROCESS FOR THE SYNTHESIS OF (1S, 2R) -MILNACIPRAN
US20100274050A1 (en) *	2009-04-23	2010-10-28	Glenmark Generics Limited	Solid milnacipran and process for the preparation of the same
WO2012145234A2 (en)	2011-04-21	2012-10-26	Emory University	Cyclopropyl derivatives and methods of use
CN103242289B (en) *	2012-02-03	2015-01-07	暨明医药科技（苏州）有限公司	Preparation method of N,N-diallyl-(1R,2R)-2-aminomethyl-1-(2-thienyl)cyclopropanecarboxamide hydrochloride
WO2014009767A1 (en)	2012-07-07	2014-01-16	Micro Labs Limited	An improved process for the preparation of 1-aryl 2-aminomethyl cyclopropane carboxyamide (z) derivatives, their isomers and salts
JP2015534464A (en)	2012-10-09	2015-12-03	カリフォルニアインスティチュートオブテクノロジー	In vivo and in vitro olefin cyclopropanation catalyzed by heme enzymes
FR2998892B1 (en) *	2012-12-04	2015-01-02	Pf Medicament	AMINOCYCLOBUTANE DERIVATIVES, PROCESS FOR PREPARING THEM AND THEIR USE AS MEDICAMENTS
CN103613513B (en) *	2013-12-09	2016-01-20	上海现代制药股份有限公司	Milnacipran hydrochloride intermediate and its preparation method and application
US9399762B2 (en)	2014-02-18	2016-07-26	California Institute Of Technology	Methods and systems for sulfimidation or sulfoximidation of organic molecules
CN104058992A (en) *	2014-06-13	2014-09-24	上海现代制药股份有限公司	Crystal form of levomilnacipran hydrochloride
CA2966437A1 (en)	2014-11-04	2016-05-12	Quimica Sintetica, S.A.	Process for the preparation of (1s,2r)-milnacipran

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2508035A1 (en) *	1981-06-23	1982-12-24	Fabre Sa Pierre	ARYL-1-AMINOMETHYL-2 CYCLOPROPANES CARBOXAMIDE (Z) DERIVATIVES, THEIR PREPARATION AND THEIR USE AS MEDICAMENTS USEFUL IN THE TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS

1985
- 1985-04-25 FR FR8506335A patent/FR2581059B1/en not_active Expired
1986
- 1986-04-14 GR GR860980A patent/GR860980B/en unknown
- 1986-04-17 AU AU56343/86A patent/AU587613B2/en not_active Expired
- 1986-04-18 ZA ZA862929A patent/ZA862929B/en unknown
- 1986-04-21 IE IE105786A patent/IE59015B1/en not_active IP Right Cessation
- 1986-04-22 NO NO861573A patent/NO165143C/en unknown
- 1986-04-22 EP EP86400873A patent/EP0200638B1/en not_active Expired
- 1986-04-22 DE DE8686400873T patent/DE3662877D1/en not_active Expired
- 1986-04-22 YU YU655/86A patent/YU44915B/en unknown
- 1986-04-22 AT AT86400873T patent/ATE42273T1/en not_active IP Right Cessation
- 1986-04-23 CA CA000507320A patent/CA1266486A/en not_active Expired - Lifetime
- 1986-04-23 KR KR1019860003133A patent/KR940006764B1/en not_active IP Right Cessation
- 1986-04-24 SU SU864027356A patent/SU1443797A3/en active
- 1986-04-24 HU HU861711A patent/HU195182B/en unknown
- 1986-04-24 JP JP61095850A patent/JPS61251650A/en active Granted
- 1986-04-24 ES ES554321A patent/ES8704449A1/en not_active Expired
- 1986-04-24 PT PT82461A patent/PT82461B/en unknown
- 1986-04-24 DK DK191286A patent/DK170888B1/en not_active IP Right Cessation
- 1986-04-24 MX MX2307A patent/MX162896B/en unknown
- 1986-04-25 FI FI861755A patent/FI87196C/en not_active IP Right Cessation
- 1986-04-25 OA OA58846A patent/OA08241A/en unknown
- 1986-04-25 AR AR30375986A patent/AR240695A1/en active
1993
- 1993-03-04 GE GEAP1993566A patent/GEP19970789B/en unknown

Also Published As

Publication number	Publication date
SU1443797A3 (en)	1988-12-07
JPH0567136B2 (en)	1993-09-24
HU195182B (en)	1988-04-28
EP0200638B1 (en)	1989-04-19
KR940006764B1 (en)	1994-07-27
ES8704449A1 (en)	1987-04-01
DK170888B1 (en)	1996-03-04
AU5634386A (en)	1986-10-30
FI861755A (en)	1986-10-26
IE59015B1 (en)	1993-12-15
GEP19970789B (en)	1997-01-28
DK191286A (en)	1986-10-26
DK191286D0 (en)	1986-04-24
YU44915B (en)	1991-04-30
JPS61251650A (en)	1986-11-08
FI87196C (en)	1992-12-10
YU65586A (en)	1987-12-31
OA08241A (en)	1987-10-30
FR2581059A1 (en)	1986-10-31
FI861755A0 (en)	1986-04-25
AR240695A1 (en)	1990-09-28
AU587613B2 (en)	1989-08-24
ATE42273T1 (en)	1989-05-15
NO165143C (en)	1991-01-09
CA1266486A (en)	1990-03-06
IE861057L (en)	1986-10-25
EP0200638A1 (en)	1986-11-05
MX162896B (en)	1991-07-08
FR2581059B1 (en)	1988-04-22
GR860980B (en)	1986-08-25
ES554321A0 (en)	1987-04-01
HUT40618A (en)	1987-01-28
NO861573L (en)	1986-10-27
KR860008126A (en)	1986-11-12
FI87196B (en)	1992-08-31
PT82461A (en)	1986-05-01
DE3662877D1 (en)	1989-05-24
PT82461B (en)	1988-10-14
NO165143B (en)	1990-09-24

Publication	Publication Date	Title
EP0215379A3 (en)	1988-08-31	Process for preparing polyvinylpyrrolidone
ZA862929B (en)	1986-12-30	Process for preparing(z)-1-phenyl-1-diethylaminocarbonyl-2-aminomethyl-cyclopropane hydrochloride
PT82062A (en)	1986-03-01	Process for preparing pyridinylimidazolidinone compounds
HUT42441A (en)	1987-07-28	Process for preparing indolyl- and indazolyl-carboxamide derivatives
EP0199997A3 (en)	1988-01-13	Process for preparing diaryl-pentaerythritol
PT82445A (en)	1986-05-01	Process for preparing novel glycopeptide derivatives
HUT42500A (en)	1987-07-28	New process for preparing sphyngosine derivatives
GR861004B (en)	1986-08-12	Process for preparing fluorized benzyltriazol compounds
PT83293B (en)	1988-10-06	Process for preparing dihidropyridine-2-hydroxyamines useful asmedicaments
PT83154A (en)	1986-09-01	Process for preparing quinolizinesulphonamides
ZA863454B (en)	1986-12-30	Process for preparing benzothiazolesulphenamides
HUT42766A (en)	1987-08-28	Process for preparing n-sulfamyl-3-(2-guanidino-thiazolyl-4-methyl-thio)-propionamidine
PT81988A (en)	1986-03-01	Process for preparing novel alkylamino-furanone derivatives
YU218086A (en)	1988-06-30	Process for preparing herbicidically effective imidazolynones
GB8800425D0 (en)	1988-02-10	Process for preparing 4 4-dialkyl-2-azetidinones
CS435886A2 (en)	1988-08-16	Process for preparing 2-brom-alfa-ergokryptine
HUT43022A (en)	1987-09-28	Process for preparing monochloro-pinacolone
HUT42432A (en)	1987-07-28	Process for preparing substituted phenyl-carbamide derivatives
HUT43039A (en)	1987-09-28	Process for preparing 4-hydroxy-2-oxo-pyrrolidin-1-yl-acetamide
HUT42769A (en)	1987-08-28	Process for preparing pyridazodiazepines
PT82643A (en)	1986-06-01	Process for preparing substituted hexanydro arylquinolizines
HUT42438A (en)	1987-07-28	Process for preparing novel 4-alkoxy-2-oxo-pyrrolidin-1-yl-acetic acid-alkylesters
HUT40795A (en)	1987-02-27	Process for preparing fluoro-alkane compounds
PT83959A (en)	1987-01-01	Process for preparing novel substituted arylfluorazolylalkanols
GB2171096B (en)	1988-12-21	Process for preparing pyrone-3-carboxamide compounds