ZA854506B - Heparin derivatives - Google Patents

Heparin derivatives

Info

Publication number
ZA854506B
ZA854506B ZA854506A ZA854506A ZA854506B ZA 854506 B ZA854506 B ZA 854506B ZA 854506 A ZA854506 A ZA 854506A ZA 854506 A ZA854506 A ZA 854506A ZA 854506 B ZA854506 B ZA 854506B
Authority
ZA
South Africa
Prior art keywords
heparin derivatives
heparin
derivatives
Prior art date
Application number
ZA854506A
Other languages
English (en)
Inventor
Wolfgang Feller
Rainer Stoermer
Annemarie Mueller
Original Assignee
Intermedicat Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Intermedicat Gmbh filed Critical Intermedicat Gmbh
Publication of ZA854506B publication Critical patent/ZA854506B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0075—Heparin; Heparan sulfate; Derivatives thereof, e.g. heparosan; Purification or extraction methods thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Polymers & Plastics (AREA)
  • Materials Engineering (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
ZA854506A 1984-06-16 1985-06-14 Heparin derivatives ZA854506B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19843422518 DE3422518A1 (de) 1984-06-16 1984-06-16 Heparin-derivate, verfahren zu ihrer herstellung, diese enthaltende arzneimittel und ihre verwendung bei der behandlung von fettstoffwechselstoerungen

Publications (1)

Publication Number Publication Date
ZA854506B true ZA854506B (en) 1986-07-30

Family

ID=6238594

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA854506A ZA854506B (en) 1984-06-16 1985-06-14 Heparin derivatives

Country Status (6)

Country Link
US (1) US4816446A (xx)
EP (1) EP0165569A3 (xx)
JP (1) JPS6169802A (xx)
DE (1) DE3422518A1 (xx)
ES (1) ES8608543A1 (xx)
ZA (1) ZA854506B (xx)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR243204A1 (es) * 1986-11-21 1993-07-30 Ajorca Sa Un metodo para la depolimerizacion quimica de polisacaridos.
US5541166A (en) * 1987-01-23 1996-07-30 The Australian National University Sulphated polysaccharides having anti-metastatic and/or anti-inflammatory activity
IL85145A (en) * 1987-01-23 1994-08-26 Univ Australian Anti-metastatic pharmacological or veterinary preparations containing modified herpin with reduced anticoagulant activity
AU3434889A (en) * 1988-03-15 1989-10-05 Jewish Hospital Of St. Louis, The Inhibition of intestinal cholesterol and fatty acid absorption
IT1234508B (it) * 1988-06-10 1992-05-19 Alfa Wassermann Spa Derivati eparinici e procedimento per la loro preparazione
DE68904264T2 (de) * 1988-08-24 1993-05-27 Akzo Nv Fragmente und fraktionen von heparin mit wirkung gegen hiv.
FR2637804B1 (fr) * 1988-10-17 1993-04-09 Sanofi Sa Compositions pharmaceutiques contenant un derive d'heparine partiellement n-desulfate a activite antithrombotique
IT1234826B (it) * 1989-01-30 1992-05-29 Alfa Wassermann Spa Derivati eparinici e procedimento per la loro preparazione
US5340932A (en) * 1989-08-18 1994-08-23 Ajorca S.A. Substances with heparin-like structure and their method of production
AR245455A1 (es) * 1989-08-18 1994-01-31 Ajorca Sa Procedimiento para la obtencion de derivados de heparina,parcial o totalmente n-acetilados en el resto glucosaminico y productos asi obtenidos excluidos sus usos farmaceuticos.
IT1243987B (it) * 1990-10-29 1994-06-28 Derivati Organici Lab Procedimento per la preparazione di epossi-eparidi prodotti ottenuti ecomposizioni farmaceutiche che li contengono
FR2669932B1 (fr) * 1990-12-03 1994-07-01 Sanofi Sa Nouvel heparosane-n,o-sulfate, son procede de preparation et les compositions pharmaceutiques qui le contiennent.
US5250519A (en) * 1991-03-29 1993-10-05 Glycomed Incorporated Non-anticoagulant heparin derivatives
US5668118A (en) * 1992-07-24 1997-09-16 Cavalier Pharmaceuticals Method of synthesis of 2-O-desulfated Heparin and use thereof for inhibition of elastase and Cathepspin G
IT1264709B1 (it) * 1993-07-12 1996-10-04 Italfarmaco Spa Derivati eparinici ad attivita' antimetastatica
AU2560995A (en) * 1994-06-06 1996-01-04 Per Bjorn Ostergaard A pharmaceutical composition comprising oligosaccharides binding to lipoprotein lipase
EP1109919A2 (en) * 1998-08-27 2001-06-27 Massachusetts Institute Of Technology Rationally designed heparinases derived from heparinase i and ii
US6933372B2 (en) * 2003-03-07 2005-08-23 Warner-Lambert Company Method to produce a solid form of heparin
US7608246B2 (en) * 2005-09-02 2009-10-27 The Brigham And Women's Hospital, Inc. Apolipoprotein E as an adjuvant for lipid antigens
WO2013169355A1 (en) 2012-05-09 2013-11-14 Paringenix, Inc. Treatment of myelosuppression
EP2961828A4 (en) 2013-02-28 2016-08-03 Harvard College COMPOSITIONS AND METHOD FOR MOBILIZING STEM CELLS
US10052346B2 (en) 2015-02-17 2018-08-21 Cantex Pharmaceuticals, Inc. Treatment of myelodysplastic syndromes with 2-O and,or 3-O desulfated heparinoids

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3151025A (en) * 1953-10-01 1964-09-29 Philips Roxane Blood lipid clearing composition
DE1201322B (de) * 1958-07-05 1965-09-23 Roussel Uclaf Verfahren zur Herstellung von N-Acylderivaten des N-Desulfoheparins
US3118816A (en) * 1962-04-03 1964-01-21 Abbott Lab N-succinyl heparin and process
CH642669A5 (de) * 1979-12-03 1984-04-30 Meyhall Chemical Ag Wasserloesliches guarprodukt und verfahren zu dessen herstellung.
ATE22899T1 (de) * 1982-06-10 1986-11-15 Kabivitrum Ab Antithrombin-heparin komplex.
IT1169888B (it) * 1983-10-25 1987-06-03 Italfarmaco Spa Glicosaminoglicani modificati dotati di attivita' antitrombotica

Also Published As

Publication number Publication date
ES544162A0 (es) 1986-06-16
EP0165569A2 (en) 1985-12-27
JPS6169802A (ja) 1986-04-10
US4816446A (en) 1989-03-28
DE3422518A1 (de) 1985-12-19
EP0165569A3 (en) 1987-05-13
ES8608543A1 (es) 1986-06-16

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