ZA844402B - Hexahydropyrrolo(2,1-a)isoquinoline derivatives - Google Patents
Hexahydropyrrolo(2,1-a)isoquinoline derivativesInfo
- Publication number
- ZA844402B ZA844402B ZA844402A ZA844402A ZA844402B ZA 844402 B ZA844402 B ZA 844402B ZA 844402 A ZA844402 A ZA 844402A ZA 844402 A ZA844402 A ZA 844402A ZA 844402 B ZA844402 B ZA 844402B
- Authority
- ZA
- South Africa
- Prior art keywords
- hexahydropyrrolo
- isoquinoline derivatives
- derivatives
- isoquinolines
- depression
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
- C07D207/273—2-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, ***e
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/06—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with radicals, containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/36—Oxygen or sulfur atoms
- C07D207/40—2,5-Pyrrolidine-diones
- C07D207/404—2,5-Pyrrolidine-diones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms, e.g. succinimide
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Psychiatry (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pain & Pain Management (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Fats And Perfumes (AREA)
- Detergent Compositions (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US50725083A | 1983-06-23 | 1983-06-23 |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA844402B true ZA844402B (en) | 1986-01-29 |
Family
ID=24017860
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA844402A ZA844402B (en) | 1983-06-23 | 1984-06-11 | Hexahydropyrrolo(2,1-a)isoquinoline derivatives |
Country Status (16)
Country | Link |
---|---|
EP (1) | EP0130069B1 (da) |
JP (1) | JPS6069082A (da) |
KR (1) | KR910002564B1 (da) |
AT (1) | ATE59041T1 (da) |
AU (1) | AU563990B2 (da) |
CA (1) | CA1253155A (da) |
DE (1) | DE3483735D1 (da) |
DK (1) | DK305184A (da) |
ES (1) | ES8602676A1 (da) |
FI (1) | FI76798C (da) |
HK (1) | HK54891A (da) |
HU (1) | HU193937B (da) |
NO (1) | NO164474C (da) |
NZ (1) | NZ208480A (da) |
SG (1) | SG44391G (da) |
ZA (1) | ZA844402B (da) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4572911A (en) * | 1984-08-02 | 1986-02-25 | Mcneilab, Inc. | Hexahydroindolinzine compounds, pharmaceutical compositions and methods and intermediates |
DE3717395A1 (de) * | 1987-05-23 | 1988-12-08 | Basf Ag | 5-phenyl-1,2,3a,4,5,9b-hexahydro-3h-benz(e) indole, ihre herstellung und verwendung als arzneimittel |
GB8718980D0 (en) * | 1987-08-11 | 1987-09-16 | May & Baker Ltd | Compositions of matter |
GB9326699D0 (en) * | 1993-12-22 | 1994-03-02 | Celltech Ltd | Chemical compounds |
WO2006138604A1 (en) | 2005-06-17 | 2006-12-28 | Janssen Pharmaceutica N.V. | Hexahydro-pyrrolo-isoquinoline compounds for the treatment of cns disorders |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BE690792A (da) * | 1966-12-07 | 1967-05-16 | ||
CH527194A (de) * | 1970-01-06 | 1972-08-31 | Hoffmann La Roche | Verfahren zur Herstellung von Isochinolin-Derivaten |
-
1984
- 1984-06-11 ZA ZA844402A patent/ZA844402B/xx unknown
- 1984-06-12 NZ NZ208480A patent/NZ208480A/en unknown
- 1984-06-12 NO NO842345A patent/NO164474C/no unknown
- 1984-06-14 CA CA000456578A patent/CA1253155A/en not_active Expired
- 1984-06-21 FI FI842533A patent/FI76798C/fi not_active IP Right Cessation
- 1984-06-22 EP EP84304247A patent/EP0130069B1/en not_active Expired - Lifetime
- 1984-06-22 HU HU842443A patent/HU193937B/hu not_active IP Right Cessation
- 1984-06-22 DK DK305184A patent/DK305184A/da unknown
- 1984-06-22 AU AU29777/84A patent/AU563990B2/en not_active Ceased
- 1984-06-22 DE DE8484304247T patent/DE3483735D1/de not_active Expired - Fee Related
- 1984-06-22 ES ES533657A patent/ES8602676A1/es not_active Expired
- 1984-06-22 AT AT84304247T patent/ATE59041T1/de not_active IP Right Cessation
- 1984-06-23 JP JP59129917A patent/JPS6069082A/ja active Pending
- 1984-06-23 KR KR1019840003577A patent/KR910002564B1/ko not_active IP Right Cessation
-
1991
- 1991-06-14 SG SG44391A patent/SG44391G/en unknown
- 1991-07-18 HK HK548/91A patent/HK54891A/xx unknown
Also Published As
Publication number | Publication date |
---|---|
AU563990B2 (en) | 1987-07-30 |
FI842533A0 (fi) | 1984-06-21 |
JPS6069082A (ja) | 1985-04-19 |
NO164474B (no) | 1990-07-02 |
FI76798C (fi) | 1988-12-12 |
ES533657A0 (es) | 1985-10-01 |
AU2977784A (en) | 1985-01-03 |
HK54891A (en) | 1991-07-26 |
FI842533A (fi) | 1984-12-24 |
CA1253155A (en) | 1989-04-25 |
HUT34478A (en) | 1985-03-28 |
SG44391G (en) | 1991-07-26 |
KR850000440A (ko) | 1985-02-27 |
DK305184D0 (da) | 1984-06-22 |
EP0130069B1 (en) | 1990-12-12 |
NZ208480A (en) | 1986-08-08 |
KR910002564B1 (ko) | 1991-04-26 |
NO842345L (no) | 1984-12-27 |
NO164474C (no) | 1990-10-10 |
EP0130069A2 (en) | 1985-01-02 |
ES8602676A1 (es) | 1985-10-01 |
DK305184A (da) | 1984-12-24 |
EP0130069A3 (en) | 1985-09-11 |
DE3483735D1 (en) | 1991-01-24 |
FI76798B (fi) | 1988-08-31 |
ATE59041T1 (de) | 1990-12-15 |
HU193937B (en) | 1987-12-28 |
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