ZA8410063B - Expression of human alpha-1-antitrypsin in yeast - Google Patents

Expression of human alpha-1-antitrypsin in yeast

Info

Publication number
ZA8410063B
ZA8410063B ZA8410063A ZA8410063A ZA8410063B ZA 8410063 B ZA8410063 B ZA 8410063B ZA 8410063 A ZA8410063 A ZA 8410063A ZA 8410063 A ZA8410063 A ZA 8410063A ZA 8410063 B ZA8410063 B ZA 8410063B
Authority
ZA
South Africa
Prior art keywords
antitrypsin
yeast
expression
human alpha
alpha
Prior art date
Application number
ZA8410063A
Inventor
Teresa Cabezon
Alex Joseph Bollen
Original Assignee
Smith Kline Rit
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smith Kline Rit filed Critical Smith Kline Rit
Publication of ZA8410063B publication Critical patent/ZA8410063B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
    • C07K14/8121—Serpins
    • C07K14/8125—Alpha-1-antitrypsin

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Mycology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
ZA8410063A 1984-01-30 1984-12-27 Expression of human alpha-1-antitrypsin in yeast ZA8410063B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US57512284A 1984-01-30 1984-01-30

Publications (1)

Publication Number Publication Date
ZA8410063B true ZA8410063B (en) 1985-10-30

Family

ID=24299041

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA8410063A ZA8410063B (en) 1984-01-30 1984-12-27 Expression of human alpha-1-antitrypsin in yeast

Country Status (9)

Country Link
EP (1) EP0151102A3 (en)
JP (1) JPS60180593A (en)
AU (1) AU3819085A (en)
DK (1) DK41585A (en)
ES (3) ES8606402A1 (en)
GR (1) GR850236B (en)
IE (1) IE850208L (en)
PT (1) PT79810B (en)
ZA (1) ZA8410063B (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60186290A (en) * 1983-08-10 1985-09-21 チモ−ジエネテイツクス　インコ−ポレ−テツド Development of alpha-1-antitrypsin by bacteria
US4711848A (en) * 1984-03-14 1987-12-08 Zymogenetics, Inc. Site specific mutagenesis in alpha-1-antitrypsin
FR2601033B1 (en) * 1986-07-02 1990-01-19 Transgene Sa VARIANTS OF GLYCOSYLATED HUMAN ALPHA-ANTITRYSPIN AND PROCESS FOR THE PREPARATION
EP0278941A1 (en) * 1987-01-30 1988-08-17 Smithkline Biologicals S.A. Expression of the P. falciparum circumsporozoite protein by yeast
FR2864152B1 (en) 2003-12-23 2007-11-23 Renault Sas MOTOR FOR VEHICLE COMPRISING AT LEAST ONE PISTON DEFINING A COMBUSTION CHAMBER

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU577259B2 (en) * 1982-08-13 1988-09-22 Zymogenetics Inc. Glycolytic promters for regulated protein expression protease inhibitor
BE895961A (en) * 1983-02-21 1983-06-16 Wallone Region PROCESS FOR THE PREPARATION OF A BACTERIAL CLONE PRODUCING HUMAN ALPHA 1-ANTITRYPSIN
AU3145184A (en) * 1983-08-16 1985-02-21 Zymogenetics Inc. High expression of foreign genes in schizosaccharomyces pombe
US4711848A (en) * 1984-03-14 1987-12-08 Zymogenetics, Inc. Site specific mutagenesis in alpha-1-antitrypsin
EP0164719B1 (en) * 1984-06-14 1992-05-06 Chiron Corporation Active site modified protease alpha-1-antitrypsin inhibitors and their production

Also Published As

Publication number Publication date
ES8606402A1 (en) 1986-04-16
ES8606502A1 (en) 1986-04-01
ES8703932A1 (en) 1987-03-01
AU3819085A (en) 1985-08-08
DK41585D0 (en) 1985-01-30
EP0151102A2 (en) 1985-08-07
ES546115A0 (en) 1987-03-01
ES546116A0 (en) 1986-04-01
ES539917A0 (en) 1986-04-16
PT79810A (en) 1985-02-01
JPS60180593A (en) 1985-09-14
GR850236B (en) 1985-05-29
DK41585A (en) 1985-07-31
IE850208L (en) 1985-07-30
PT79810B (en) 1986-10-28
EP0151102A3 (en) 1986-07-09

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