ZA825513B - New derivatives of pyridazine active on the central nervous system - Google Patents

New derivatives of pyridazine active on the central nervous system

Info

Publication number: ZA825513B
Authority: ZA; South Africa
Prior art keywords: pyridazine; active; nervous system; central nervous; new derivatives
Prior art date: 1981-08-07

Application number

ZA825513A

Other languages

English (en)

Inventor

Jean-Paul Kan

Kathleen Biziere

Camille Georges Wermuth

Original Assignee

Sanofi Sa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1981-08-07

Filing date

1982-07-30

Publication date

1983-06-29

1982-07-30 Application filed by Sanofi Sa filed Critical Sanofi Sa

1983-06-29 Publication of ZA825513B publication Critical patent/ZA825513B/xx

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
- C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D237/20—Nitrogen atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, ***e

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Psychiatry (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Biomedical Technology (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pain & Pain Management (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

ZA825513A 1981-08-07 1982-07-30 New derivatives of pyridazine active on the central nervous system ZA825513B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
FR8115380A FR2510998B1 (fr)	1981-08-07	1981-08-07	Nouveaux derives amines de la pyridazine, leur procede de preparation et les medicaments, a action desinhibitrice, qui en comportent

Publications (1)

Publication Number	Publication Date
ZA825513B true ZA825513B (en)	1983-06-29

Family

ID=9261294

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
ZA825513A ZA825513B (en)	1981-08-07	1982-07-30	New derivatives of pyridazine active on the central nervous system
ZA825512A ZA825512B (en)	1981-08-07	1982-07-30	New amino compounds derived from pyridazine,active on the central nervous system

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
ZA825512A ZA825512B (en)	1981-08-07	1982-07-30	New amino compounds derived from pyridazine,active on the central nervous system

Country Status (30)

Country	Link
US (1)	US4508720A (xx)
EP (2)	EP0072726B1 (xx)
JP (2)	JPS5877868A (xx)
KR (2)	KR880001624B1 (xx)
AR (2)	AR231441A1 (xx)
AT (2)	ATE12227T1 (xx)
AU (2)	AU548931B2 (xx)
CA (2)	CA1179346A (xx)
CS (2)	CS229941B2 (xx)
DD (2)	DD202715A5 (xx)
DE (2)	DE3262671D1 (xx)
DK (2)	DK148795C (xx)
EG (2)	EG15788A (xx)
ES (2)	ES8305737A1 (xx)
FI (2)	FI72968C (xx)
FR (1)	FR2510998B1 (xx)
GR (2)	GR76430B (xx)
HU (2)	HU190028B (xx)
IE (2)	IE53387B1 (xx)
IL (2)	IL66408A (xx)
MA (2)	MA19560A1 (xx)
NO (2)	NO157861C (xx)
NZ (2)	NZ201518A (xx)
OA (2)	OA07175A (xx)
PH (1)	PH18545A (xx)
PL (2)	PL137199B1 (xx)
PT (2)	PT75351B (xx)
SU (2)	SU1138024A3 (xx)
YU (2)	YU172082A (xx)
ZA (2)	ZA825513B (xx)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2540113A1 (fr) *	1983-01-27	1984-08-03	Sanofi Sa	Acides derives de la pyridazine actifs sur le systeme nerveux central
CA1218655A (en) *	1983-01-28	1987-03-03	Kathleen Biziere	Process for the preparation of pyridazine derivatives having a psychotropic action
US4628088A (en) *	1984-07-17	1986-12-09	Eli Lilly And Company	Preparation of substituted pyridazines
DE3664772D1 (en) *	1985-01-14	1989-09-07	Boehringer Ingelheim Kg	12-amino pyridazinoû4',5':3,4¨pyrroloû2,1-a¨isoquinolines, process for their preparation and use
FR2642754B1 (fr) *	1989-02-07	1991-05-24	Sanofi Sa	Nouveaux derives de la pyridazine, procede de preparation et compositions pharmaceutiques en contenant
US5631255A (en) *	1989-02-07	1997-05-20	Sanofi	Pyridazine derivatives
PT93060B (pt)	1989-02-07	1995-12-29	Sanofi Sa	Processo para a obtencao de derivados de piridazina e de composicoes farmaceuticas que os contem
US5461053A (en) *	1989-02-07	1995-10-24	Sanofi	Pyridazine derivatives
FR2665442B1 (fr) *	1990-07-31	1992-12-04	Sanofi Sa	Derives d'alkyl-6 pyridazine, procede de preparation et compositions pharmaceutiques en contenant.
FR2654727B1 (fr) *	1989-11-17	1992-03-27	Sanofi Sa	Derives de la pyridazine, procede de preparation et compositions pharmaceutiques en contenant.
FR2663326B2 (fr) *	1989-11-17	1992-10-16	Sanofi Sa	Derives de la pyridazine, procede de preparation et compositions pharmaceutiques en contenant.
FR2642648B1 (fr) *	1989-02-07	1991-06-21	Sanofi Sa	Utilisation de derives d'alkyl-5 pyridazine comme medicaments actifs sur le systeme cholinergique
FR2676444B1 (fr) *	1991-05-16	1995-03-10	Sanofi Elf	Nouveaux derives d'amino-3 pyridazines actifs sur le systeme nerveux central, procede de preparation et compositions pharmaceutiques en contenant.
US20100210590A1 (en) *	1995-09-27	2010-08-19	Northwestern University	Compositions and treatments for seizure-related disorders
US20030176437A1 (en) *	2001-08-31	2003-09-18	D.M. Watterson	Anti-inflammatory and protein kinase inhibitor compositions and related methods for downregulation of detrimental cellular responses and inhibition of cell death
AU2003246979B8 (en) *	2002-08-13	2009-08-06	Merck Sharp & Dohme Limited	Phenylpyridazine derivatives as ligands for GABA receptors
EP1812007B1 (en) *	2004-11-02	2011-09-07	Northwestern University	Pyridazine compounds and methods
ES2441718T3 (es)	2004-11-02	2014-02-06	Northwestern University	Compuestos de piridazina, composiciones y métodos
US20090325973A1 (en) *	2006-04-28	2009-12-31	Watterson D Martin	Formulations containing pyridazine compounds
EP2015750A2 (en) *	2006-04-28	2009-01-21	Northwestern University	Compositions and treatments using pyridazine compounds and cholinesterase inhibitors
CA2650704A1 (en) *	2006-04-28	2007-11-08	Northwestern University	Salts of pyridazine compounds
RU2555969C1 (ru) *	2014-07-09	2015-07-10	Юлия Алексеевна Щепочкина	Керамическая масса для изготовления облицовочной плитки

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1345880A (en) *	1971-06-18	1974-02-06	Cepbepe	Pyridazine derivatives

1981
- 1981-08-07 FR FR8115380A patent/FR2510998B1/fr not_active Expired
1982
- 1982-07-21 NO NO822509A patent/NO157861C/no unknown
- 1982-07-21 NO NO822510A patent/NO157102C/no unknown
- 1982-07-23 IE IE1778/82A patent/IE53387B1/en not_active IP Right Cessation
- 1982-07-23 IE IE1779/82A patent/IE53388B1/en not_active IP Right Cessation
- 1982-07-26 GR GR68873A patent/GR76430B/el unknown
- 1982-07-26 GR GR68868A patent/GR76429B/el unknown
- 1982-07-27 IL IL66408A patent/IL66408A/xx unknown
- 1982-07-27 IL IL66409A patent/IL66409A/xx unknown
- 1982-07-29 US US06/402,906 patent/US4508720A/en not_active Expired - Fee Related
- 1982-07-29 AU AU86554/82A patent/AU548931B2/en not_active Ceased
- 1982-07-29 AU AU86553/82A patent/AU548930B2/en not_active Ceased
- 1982-07-30 AT AT82401425T patent/ATE12227T1/de not_active IP Right Cessation
- 1982-07-30 ZA ZA825513A patent/ZA825513B/xx unknown
- 1982-07-30 EP EP82401425A patent/EP0072726B1/fr not_active Expired
- 1982-07-30 ZA ZA825512A patent/ZA825512B/xx unknown
- 1982-07-30 EP EP82401424A patent/EP0074863B1/fr not_active Expired
- 1982-07-30 PT PT75351A patent/PT75351B/pt not_active IP Right Cessation
- 1982-07-30 DE DE8282401425T patent/DE3262671D1/de not_active Expired
- 1982-07-30 AT AT82401424T patent/ATE18216T1/de not_active IP Right Cessation
- 1982-07-30 DE DE8282401424T patent/DE3269383D1/de not_active Expired
- 1982-07-30 PT PT75350A patent/PT75350B/pt not_active IP Right Cessation
- 1982-08-02 MA MA19771A patent/MA19560A1/fr unknown
- 1982-08-02 MA MA19773A patent/MA19562A1/fr unknown
- 1982-08-03 CS CS825800A patent/CS229941B2/cs unknown
- 1982-08-03 CS CS825799A patent/CS229940B2/cs unknown
- 1982-08-04 EG EG473/82A patent/EG15788A/xx active
- 1982-08-04 EG EG82474A patent/EG15747A/xx active
- 1982-08-06 FI FI822747A patent/FI72968C/fi not_active IP Right Cessation
- 1982-08-06 JP JP57137833A patent/JPS5877868A/ja active Pending
- 1982-08-06 PH PH27679A patent/PH18545A/en unknown
- 1982-08-06 DK DK354482A patent/DK148795C/da not_active IP Right Cessation
- 1982-08-06 PL PL1982237808A patent/PL137199B1/pl unknown
- 1982-08-06 CA CA000408844A patent/CA1179346A/en not_active Expired
- 1982-08-06 OA OA57767A patent/OA07175A/xx unknown
- 1982-08-06 YU YU01720/82A patent/YU172082A/xx unknown
- 1982-08-06 JP JP57137832A patent/JPS5877867A/ja active Granted
- 1982-08-06 NZ NZ201518A patent/NZ201518A/en unknown
- 1982-08-06 ES ES514794A patent/ES8305737A1/es not_active Expired
- 1982-08-06 AR AR290242A patent/AR231441A1/es active
- 1982-08-06 ES ES514795A patent/ES514795A0/es active Granted
- 1982-08-06 SU SU823475704A patent/SU1138024A3/ru active
- 1982-08-06 OA OA57768A patent/OA07176A/xx unknown
- 1982-08-06 NZ NZ201520A patent/NZ201520A/xx unknown
- 1982-08-06 HU HU822545A patent/HU190028B/hu not_active IP Right Cessation
- 1982-08-06 HU HU822542A patent/HU189166B/hu not_active IP Right Cessation
- 1982-08-06 YU YU01718/82A patent/YU171882A/xx unknown
- 1982-08-06 CA CA000408843A patent/CA1174240A/en not_active Expired
- 1982-08-06 DK DK354382A patent/DK148537C/da not_active IP Right Cessation
- 1982-08-06 AR AR290243A patent/AR231637A1/es active
- 1982-08-06 SU SU823476698A patent/SU1140685A3/ru active
- 1982-08-06 PL PL1982237809A patent/PL130647B1/pl unknown
- 1982-08-06 FI FI822748A patent/FI72969C/fi not_active IP Right Cessation
- 1982-08-07 KR KR8203558A patent/KR880001624B1/ko active
- 1982-08-07 KR KR8203557A patent/KR890001569B1/ko active
- 1982-08-09 DD DD82242356A patent/DD202715A5/de unknown
- 1982-08-09 DD DD82242359A patent/DD202549A5/de unknown

Also Published As

Publication number	Publication date
EP0072726A1 (fr)	1983-02-23
IE53387B1 (en)	1988-10-26
FR2510998A1 (fr)	1983-02-11
AR231637A1 (es)	1985-01-31
JPS5877867A (ja)	1983-05-11
FI822748A0 (fi)	1982-08-06
PL237809A1 (en)	1983-02-28
FI822747L (fi)	1983-02-08
EP0072726B1 (fr)	1985-03-20
DK148795B (da)	1985-09-30
ES514794A0 (es)	1983-04-16
GR76429B (xx)	1984-08-10
MA19562A1 (fr)	1983-04-01
AR231441A1 (es)	1984-11-30
OA07176A (fr)	1984-04-30
ES8305737A1 (es)	1983-04-16
AU8655482A (en)	1983-02-10
NZ201518A (en)	1985-04-30
EG15747A (en)	1986-06-30
CA1174240A (en)	1984-09-11
DK354482A (da)	1983-02-08
FR2510998B1 (fr)	1986-01-10
AU548931B2 (en)	1986-01-09
KR840001159A (ko)	1984-03-28
ES8305738A1 (es)	1983-04-16
DK148795C (da)	1986-03-10
HU190028B (en)	1986-08-28
DK354382A (da)	1983-02-08
NO157861B (no)	1988-02-22
OA07175A (fr)	1984-04-30
IL66409A0 (en)	1982-11-30
DK148537B (da)	1985-07-29
ES514795A0 (es)	1983-04-16
FI72968B (fi)	1987-04-30
IL66408A (en)	1985-12-31
IE821778L (en)	1983-02-07
NO157102C (no)	1988-01-20
YU171882A (en)	1985-03-20
NO157861C (no)	1988-06-01
DE3262671D1 (en)	1985-04-25
CA1179346A (en)	1984-12-11
CS229941B2 (en)	1984-07-16
ATE12227T1 (de)	1985-04-15
PT75350A (fr)	1982-08-01
ATE18216T1 (de)	1986-03-15
FI72969C (fi)	1987-08-10
JPS5877868A (ja)	1983-05-11
FI822747A0 (fi)	1982-08-06
FI72968C (fi)	1987-08-10
DK148537C (da)	1986-01-13
PH18545A (en)	1985-08-09
SU1138024A3 (ru)	1985-01-30
GR76430B (xx)	1984-08-10
KR840001145A (ko)	1984-03-28
EP0074863A1 (fr)	1983-03-23
PT75351B (fr)	1984-08-01
KR880001624B1 (ko)	1988-09-02
PL237808A1 (en)	1983-02-28
HU189166B (en)	1986-06-30
FI822748L (fi)	1983-02-08
PT75350B (fr)	1984-08-01
US4508720A (en)	1985-04-02
NZ201520A (en)	1985-04-30
SU1140685A3 (ru)	1985-02-15
PT75351A (fr)	1982-08-01
IL66409A (en)	1985-09-29
MA19560A1 (fr)	1983-04-01
IE53388B1 (en)	1988-10-26
DE3269383D1 (en)	1986-04-03
EG15788A (en)	1986-09-30
KR890001569B1 (ko)	1989-05-08
NO822510L (no)	1983-02-08
AU548930B2 (en)	1986-01-09
FI72969B (fi)	1987-04-30
ZA825512B (en)	1983-06-29
DD202715A5 (de)	1983-09-28
IE821779L (en)	1983-02-07
DD202549A5 (de)	1983-09-21
IL66408A0 (en)	1982-11-30
YU172082A (en)	1985-03-20
NO822509L (no)	1983-02-08
AU8655382A (en)	1983-02-10
JPH0459312B2 (xx)	1992-09-21
EP0074863B1 (fr)	1986-02-26
PL137199B1 (en)	1986-05-31
NO157102B (no)	1987-10-12
CS229940B2 (en)	1984-07-16
PL130647B1 (en)	1984-08-31

Publication	Publication Date	Title
ZA825513B (en)	1983-06-29	New derivatives of pyridazine active on the central nervous system
GB2170400B (en)	1988-10-26	Caster
SG93690G (en)	1991-01-18	Pyridazine derivatives active on the central nervous system,preparation process and medicines containing them
ZA825515B (en)	1983-06-29	New derivatives of pyridazine active on the central nervous system
ZA868842B (en)	1988-07-27	The selective hydrogenation of acetylene
DE3565933D1 (en)	1988-12-08	Anus-praeter supply system
DE3467894D1 (en)	1988-01-14	Dihydroxybenzamide derivatives having anti-inflammatory activity
JPS57148908A (en)	1982-09-14	Attachable type infant chair
GB2111558B (en)	1985-10-02	Puk-holder assemblies
GB8500391D0 (en)	1985-02-13	Central locking system
EP0174446A3 (en)	1988-01-07	Distributed multiprocessing system
AU9057982A (en)	1983-05-18	Locking assemblies
GB2098423B (en)	1985-07-03	Active equalizer
GB2116544B (en)	1985-06-19	Cyclohexanone derivatives
GB2093732B (en)	1985-06-12	Spraying system
GB2110851B (en)	1985-04-24	Radiopaging systems
JPS57130198A (en)	1982-08-12	Tracking system
EP0162079A4 (en)	1989-01-19	USE OF ARG-PHE-AMIDE DERIVATIVES.
GB8432702D0 (en)	1985-02-06	Maintaining alertness
GB2098878B (en)	1985-06-26	Selective oxidizing system for the preparation of ortho-dihydroxylated or ortho-dialkoxylated aromatic derivatives
AU8843582A (en)	1983-03-24	Activity chair
IE852679L (en)	1986-05-01	Pyridazines.
GB2112261B (en)	1985-07-17	Hinge-type offset wheel harrow
GB8411707D0 (en)	1984-06-13	Combined alarm system
GB8425416D0 (en)	1984-11-14	Ring electrode retaining system