ZA773055B - 12-azaprostanoic acids - Google Patents

12-azaprostanoic acids

Info

Publication number
ZA773055B
ZA773055B ZA00773055A ZA773055A ZA773055B ZA 773055 B ZA773055 B ZA 773055B ZA 00773055 A ZA00773055 A ZA 00773055A ZA 773055 A ZA773055 A ZA 773055A ZA 773055 B ZA773055 B ZA 773055B
Authority
ZA
South Africa
Prior art keywords
azaprostanoic
acids
azaprostanoic acids
Prior art date
Application number
ZA00773055A
Other languages
English (en)
Inventor
T Lee
R Smith
E Cragoe
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of ZA773055B publication Critical patent/ZA773055B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D309/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/10Oxygen atoms
    • C07D309/12Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00Ethers; Compounds having groups, groups or groups
    • C07C43/02Ethers
    • C07C43/03Ethers having all ether-oxygen atoms bound to acyclic carbon atoms
    • C07C43/14Unsaturated ethers
    • C07C43/178Unsaturated ethers containing hydroxy or O-metal groups
    • C07C43/1782Unsaturated ethers containing hydroxy or O-metal groups containing six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/27Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation
    • C07C45/29Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation of hydroxy groups
    • C07C45/292Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation of hydroxy groups with chromium derivatives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/51Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition
    • C07C45/511Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition involving transformation of singly bound oxygen functional groups to >C = O groups
    • C07C45/515Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition involving transformation of singly bound oxygen functional groups to >C = O groups the singly bound functional group being an acetalised, ketalised hemi-acetalised, or hemi-ketalised hydroxyl group
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C47/00Compounds having —CHO groups
    • C07C47/20Unsaturated compounds having —CHO groups bound to acyclic carbon atoms
    • C07C47/277Unsaturated compounds having —CHO groups bound to acyclic carbon atoms containing ether groups, groups, groups, or groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/08Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D277/12Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/14Oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
ZA00773055A 1976-05-24 1977-05-23 12-azaprostanoic acids ZA773055B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/689,318 US4022794A (en) 1976-05-24 1976-05-24 Novel analogs of prostaglandins with 4-oxo-thiazolidinyl nucleus and method of preparation thereof

Publications (1)

Publication Number Publication Date
ZA773055B true ZA773055B (en) 1979-01-31

Family

ID=24767935

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA00773055A ZA773055B (en) 1976-05-24 1977-05-23 12-azaprostanoic acids

Country Status (13)

Country Link
US (1) US4022794A (xx)
JP (1) JPS52144669A (xx)
AU (1) AU511569B2 (xx)
BE (1) BE854925A (xx)
DE (1) DE2723237A1 (xx)
DK (1) DK206677A (xx)
ES (1) ES459050A1 (xx)
FR (1) FR2352808A1 (xx)
GB (1) GB1548820A (xx)
HU (1) HU178639B (xx)
NL (1) NL7705224A (xx)
SE (1) SE7705370L (xx)
ZA (1) ZA773055B (xx)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4087435A (en) * 1977-02-17 1978-05-02 Merck & Co., Inc. 8-Aza-9-dioxothiaprostanoic acids
US4130566A (en) * 1977-10-27 1978-12-19 Sumitomo Chemical Company, Limited Process for producing 5-carboxy-2-acetylthiophene
US4402969A (en) * 1981-03-23 1983-09-06 Merck & Co., Inc. Antihypertensive proline derivatives
US4532138A (en) * 1981-11-20 1985-07-30 Syntex (U.S.A.) Inc. Thiazolidin-2-one analogs
US4866087A (en) * 1982-01-21 1989-09-12 Merck & Co., Inc. Carboxyalkyl urea compounds and derivatives thereof useful as angiotensin converting enzyme inhibitors and as antihypertensives
US4639460A (en) * 1985-08-05 1987-01-27 Chevron Research Company Fungicidal substituted N-(1-iodopropargyl)thiazolidinones
GB0014356D0 (en) * 2000-06-12 2000-08-02 Colover Jack Treatment of multiple sclerosis
US6858615B2 (en) 2002-02-19 2005-02-22 Parion Sciences, Inc. Phenyl guanidine sodium channel blockers
US6903105B2 (en) * 2003-02-19 2005-06-07 Parion Sciences, Inc. Sodium channel blockers
US20050090505A1 (en) * 2003-08-18 2005-04-28 Johnson Michael R. Methods of reducing risk of infection from pathogens
US7745442B2 (en) * 2003-08-20 2010-06-29 Parion Sciences, Inc. Methods of reducing risk of infection from pathogens
JP2011520811A (ja) * 2008-05-09 2011-07-21 アラーガン インコーポレイテッド 治療用の置換チアゾリジノン類、オキサゾリジノン類および関連化合物
JP2012184201A (ja) * 2011-03-07 2012-09-27 Nippon Zeon Co Ltd 環状エーテル化合物、非水系電池電極用バインダー組成物、非水系電池電極用スラリー組成物、非水系電池用電極及び非水系電池
AR086745A1 (es) 2011-06-27 2014-01-22 Parion Sciences Inc 3,5-diamino-6-cloro-n-(n-(4-(4-(2-(hexil(2,3,4,5,6-pentahidroxihexil)amino)etoxi)fenil)butil)carbamimidoil)pirazina-2-carboxamida
BR112015014178A2 (pt) 2012-12-17 2017-07-11 Parion Sciences Inc compostos de 3,5-diamino-6-cloro-n-(n-(4-fenilbutil)carbamimidoil) pirazina-2- carboxamida
BR112015014349A2 (pt) 2012-12-17 2017-07-11 Parion Sciences Inc derivados de cloro-pirazina carboxamida úteis para o tratamento de doenças favorecidas por hidratação mucosa insuficiente
US9102633B2 (en) 2013-12-13 2015-08-11 Parion Sciences, Inc. Arylalkyl- and aryloxyalkyl-substituted epithelial sodium channel blocking compounds

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU169072B (xx) * 1974-05-14 1976-09-28

Also Published As

Publication number Publication date
AU511569B2 (en) 1980-08-28
US4022794A (en) 1977-05-10
DE2723237A1 (de) 1977-12-15
GB1548820A (en) 1979-07-18
AU2524177A (en) 1978-11-23
JPS52144669A (en) 1977-12-02
FR2352808A1 (fr) 1977-12-23
ES459050A1 (es) 1978-11-01
SE7705370L (sv) 1977-11-25
NL7705224A (nl) 1977-11-28
DK206677A (da) 1977-11-25
FR2352808B1 (xx) 1981-04-30
BE854925A (fr) 1977-11-23
HU178639B (en) 1982-06-28

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