ZA735453B - Improvements in or relating to the preparation of 17 x-esters of 17d,21-dihydroxy-20-oxo-steroids - Google Patents

Improvements in or relating to the preparation of 17 x-esters of 17d,21-dihydroxy-20-oxo-steroids

Info

Publication number
ZA735453B
ZA735453B ZA735453A ZA735453A ZA735453B ZA 735453 B ZA735453 B ZA 735453B ZA 735453 A ZA735453 A ZA 735453A ZA 735453 A ZA735453 A ZA 735453A ZA 735453 B ZA735453 B ZA 735453B
Authority
ZA
South Africa
Prior art keywords
steroids
dihydroxy
oxo
esters
relating
Prior art date
Application number
ZA735453A
Other languages
English (en)
Inventor
G Durrant
G Phillipps
G Bain
Original Assignee
Glaxo Lab Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Lab Ltd filed Critical Glaxo Lab Ltd
Publication of ZA735453B publication Critical patent/ZA735453B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F1/00Compounds containing elements of Groups 1 or 11 of the Periodic Table
    • C07F1/005Compounds containing elements of Groups 1 or 11 of the Periodic Table without C-Metal linkages
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F1/00Compounds containing elements of Groups 1 or 11 of the Periodic Table
    • C07F1/08Copper compounds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/06Phosphorus compounds without P—C bonds
    • C07F9/08Esters of oxyacids of phosphorus

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Steroid Compounds (AREA)
ZA735453A 1972-08-11 1973-08-10 Improvements in or relating to the preparation of 17 x-esters of 17d,21-dihydroxy-20-oxo-steroids ZA735453B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB3765572A GB1440063A (en) 1972-08-11 1972-08-11 17alpha-esters of 17alpha,21-dihydroxy-20-oxo-steroids

Publications (1)

Publication Number Publication Date
ZA735453B true ZA735453B (en) 1974-10-30

Family

ID=10398029

Family Applications (2)

Application Number Title Priority Date Filing Date
ZA735452A ZA735452B (en) 1972-08-11 1973-08-10 Improvemnts in or relating to steroid compounds
ZA735453A ZA735453B (en) 1972-08-11 1973-08-10 Improvements in or relating to the preparation of 17 x-esters of 17d,21-dihydroxy-20-oxo-steroids

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ZA735452A ZA735452B (en) 1972-08-11 1973-08-10 Improvemnts in or relating to steroid compounds

Country Status (16)

Country Link
US (1) US3891631A (de)
JP (1) JPS5752359B2 (de)
BE (1) BE803461A (de)
CA (1) CA1027109A (de)
CH (1) CH590884A5 (de)
DE (1) DE2340591A1 (de)
DK (1) DK135998B (de)
ES (1) ES417738A1 (de)
FR (1) FR2205508B1 (de)
GB (1) GB1440063A (de)
IE (1) IE38312B1 (de)
IL (1) IL42942A (de)
LU (1) LU68212A1 (de)
NL (1) NL7311072A (de)
SE (1) SE387951B (de)
ZA (2) ZA735452B (de)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1516095A (en) * 1974-07-31 1978-06-28 Glaxo Lab Ltd 17,21-diesters of 17alpha,21-dihydroxy-steroids of the pregnane series
GB1593978A (en) * 1976-12-31 1981-07-22 Lark Spa Anti-inflammatory steroids
US4086254A (en) * 1977-04-13 1978-04-25 The Upjohn Company Photocleavable steroids
DE2735110A1 (de) * 1977-08-04 1979-02-15 Hoechst Ag Corticoid-17-alkylcarbonate und verfahren zu ihrer herstellung
DE2759135A1 (de) * 1977-12-30 1979-07-19 Lark Spa Neue steroidverbindungen und deren herstellung und verwendung
DE2817988A1 (de) * 1978-04-25 1979-11-08 Hoechst Ag Corticoid 17-alkylcarbonate und verfahren zu deren herstellung
JPS58161340A (ja) * 1982-03-19 1983-09-24 Hitachi Ltd 製品移送装置
AU558725B2 (en) * 1983-09-07 1987-02-05 Mitsubishi Kasei Corporation Corticoid derivatives
JPH0527014Y2 (de) * 1985-10-31 1993-07-08
DE3637806A1 (de) * 1986-11-06 1988-05-19 Hoechst Ag Verfahren zur herstellung von prednisolon-17-ethylcarbonat durch umlagerung von prednisolon-21-ethylcarbonat
FR2683530B1 (fr) * 1991-11-08 1994-01-21 Roussel Uclaf Nouveau procede de preparation de derives 20-oxo 17 alpha, 21-dihydroxyles du pregnane et nouveaux intermediaires.
AR032471A1 (es) * 2000-08-05 2003-11-12 Glaxo Group Ltd Derivado de androstano y solvatos del mismo, su uso para la fabricacion de medicamentos, composiciones farmaceuticas que los comprenden, procesos para preparar tales derivados, intermediarios utiles en la preparacion de tales derivados, procesos para preparar tales intermediarios, y compuestos inter
US6759398B2 (en) * 2000-08-05 2004-07-06 Smithkline Beecham Corporation Anti-inflammatory androstane derivative
GB0019172D0 (en) * 2000-08-05 2000-09-27 Glaxo Group Ltd Novel compounds
US6858596B2 (en) * 2000-08-05 2005-02-22 Smithkline Beecham Corporation Formulation containing anti-inflammatory androstane derivative
US6777399B2 (en) * 2000-08-05 2004-08-17 Smithkline Beecham Corporation Anti-inflammatory androstane derivative compositions
CA2445839A1 (en) * 2001-04-30 2002-11-07 Glaxo Group Limited Anti-inflammatory 17.beta.-carbothioate ester derivatives of androstane with a cyclic ester group in position 17.alpha
AU2002356759A1 (en) * 2001-12-01 2003-06-17 Glaxo Group Limited 17.alpha. -cyclic esters of 16-methylpregnan-3,20-dione as anti-inflammatory agents
US20050175545A1 (en) * 2002-02-04 2005-08-11 Keith Biggadike Formulation for inhalation comprising a glucocorticoid and a beta 2-adrenoreceptor agonist
GB0202635D0 (en) * 2002-02-05 2002-03-20 Glaxo Wellcome Mfg Pte Ltd Formulation containing novel anti-inflammatory androstane derivative
GB2389530B (en) * 2002-06-14 2007-01-10 Cipla Ltd Pharmaceutical compositions
GB0507165D0 (en) * 2005-04-08 2005-05-18 Glaxo Group Ltd Novel crystalline pharmaceutical product
GB0615108D0 (en) * 2006-07-28 2006-09-06 Glaxo Group Ltd Novel formulations
HUE046243T2 (hu) 2008-05-28 2020-02-28 Reveragen Biopharma Inc Nem-hormonális NF-KB szteroid modulátorok betegség kezelésére
EP2556083A4 (de) 2010-04-05 2013-12-04 Validus Biopharma Inc Nichthormonale steroide modulatoren von nf-kappa-b zur krankheitsbehandlung
WO2017004205A1 (en) 2015-06-29 2017-01-05 Reveragen Biopharma, Inc. NON-HORMONAL STEROID MODULATORS OF NF-κB FOR TREATMENT OF DISEASE
US11382922B2 (en) 2019-03-07 2022-07-12 Reveragen Biopharma, Inc. Aqueous oral pharmaceutical suspension compositions

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3255218A (en) * 1962-03-28 1966-06-07 Schering Corp 17(20)-enol-21-aldehydes of the pregnane series
US3780177A (en) * 1967-06-16 1973-12-18 Warner Lambert Co 17-butyrate,21-ester derivatives of 6alpha,9alpha-difluoroprednisolone,compositions and use
IT1034011B (it) * 1969-06-26 1979-09-10 Vister Vismara Terapeutici S P Processo per la prapratzione di 17 monoesteri di 17 a 21 diossisteroidi per idrolisi die corpispondenti 17 21 ortoesteri ciclici a ph control lato

Also Published As

Publication number Publication date
NL7311072A (de) 1974-02-13
CA1027109A (en) 1978-02-28
FR2205508B1 (de) 1978-09-15
ZA735452B (en) 1974-07-31
IL42942A0 (en) 1973-11-28
IE38312L (en) 1974-02-11
ES417738A1 (es) 1976-06-16
IE38312B1 (en) 1978-02-15
BE803461A (fr) 1974-02-11
AU5914373A (en) 1975-02-13
CH590884A5 (de) 1977-08-31
DK135998C (de) 1977-12-27
US3891631A (en) 1975-06-24
FR2205508A1 (de) 1974-05-31
IL42942A (en) 1977-05-31
DE2340591A1 (de) 1974-03-07
JPS5752359B2 (de) 1982-11-06
LU68212A1 (de) 1973-10-16
DK135998B (da) 1977-07-25
GB1440063A (en) 1976-06-23
JPS4985062A (de) 1974-08-15
SE387951B (sv) 1976-09-20

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