ZA201104349B - Pharmaceutical preparation comprising supernatant of blood mononuclear cell culture - Google Patents

Pharmaceutical preparation comprising supernatant of blood mononuclear cell culture

Info

Publication number
ZA201104349B
ZA201104349B ZA2011/04349A ZA201104349A ZA201104349B ZA 201104349 B ZA201104349 B ZA 201104349B ZA 2011/04349 A ZA2011/04349 A ZA 2011/04349A ZA 201104349 A ZA201104349 A ZA 201104349A ZA 201104349 B ZA201104349 B ZA 201104349B
Authority
ZA
South Africa
Prior art keywords
supernatant
cell culture
pharmaceutical preparation
blood mononuclear
mononuclear cell
Prior art date
Application number
ZA2011/04349A
Inventor
Hendrik Jan Ankersmit
Original Assignee
Aposcience Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aposcience Ag filed Critical Aposcience Ag
Publication of ZA201104349B publication Critical patent/ZA201104349B/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/16—Blood plasma; Blood serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/17—Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/46—Cellular immunotherapy
    • A61K39/461—Cellular immunotherapy characterised by the cell type used
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/46—Cellular immunotherapy
    • A61K39/462—Cellular immunotherapy characterized by the effect or the function of the cells
    • A61K39/4621—Cellular immunotherapy characterized by the effect or the function of the cells immunosuppressive or immunotolerising
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/46—Cellular immunotherapy
    • A61K39/464—Cellular immunotherapy characterised by the antigen targeted or presented
    • A61K39/4643—Vertebrate antigens
    • A61K39/46433—Antigens related to auto-immune diseases; Preparations to induce self-tolerance
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Cell Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Virology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Dermatology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Surgery (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
ZA2011/04349A 2008-12-18 2011-06-10 Pharmaceutical preparation comprising supernatant of blood mononuclear cell culture ZA201104349B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP08450198A EP2198873A1 (en) 2008-12-18 2008-12-18 Pharmaceutical preparation comprising supernatant of blood mononuclear cell culture
PCT/EP2009/067534 WO2010079086A1 (en) 2008-12-18 2009-12-18 Pharmaceutical preparation comprising supernatant of blood mononuclear cell culture

Publications (1)

Publication Number Publication Date
ZA201104349B true ZA201104349B (en) 2012-02-29

Family

ID=40478351

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA2011/04349A ZA201104349B (en) 2008-12-18 2011-06-10 Pharmaceutical preparation comprising supernatant of blood mononuclear cell culture

Country Status (13)

Country Link
US (1) US11235003B2 (en)
EP (2) EP2198873A1 (en)
JP (1) JP5869343B2 (en)
CN (1) CN102256608B (en)
AU (1) AU2009336668B2 (en)
BR (1) BRPI0922174A2 (en)
CA (1) CA2746862C (en)
ES (1) ES2429518T3 (en)
NZ (1) NZ593364A (en)
PL (1) PL2379085T3 (en)
RU (1) RU2533253C2 (en)
WO (1) WO2010079086A1 (en)
ZA (1) ZA201104349B (en)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2011009277A (en) * 2009-03-05 2011-12-16 Macrocure Ltd Activated leukocyte composition.
WO2015046627A1 (en) * 2013-09-30 2015-04-02 国立大学法人九州大学 Wound healing promoter
KR102215667B1 (en) * 2016-05-30 2021-02-16 주식회사 젬백스앤카엘 Composition for skin regeneration and anti-aging comprising peripheral blood-derived mononuclear cells and platelet-rich plasma, and skin regeneration method using the same
TWI732787B (en) * 2016-10-04 2021-07-11 訊聯生物科技股份有限公司 Preparation method of multi-peptide composition stimulated by temperature regulation
EP3305306A1 (en) * 2016-10-04 2018-04-11 Dr. Sarah Prinzessin von Isenburg Compositions comprising adjustable concentrations of growth factors derived from blood serum and clot hypoxia-conditioned medium and methods of their production
CN106265738A (en) * 2016-11-11 2017-01-04 上海鸣大生物科技有限公司 A kind of external used medicine for treating pathogenic infection dermatoses and its preparation method and application
CN106344612A (en) * 2016-11-11 2017-01-25 上海鸣大生物科技有限公司 External medicine for treating autoimmune dermatosis and preparation method and application thereof
CN106491645A (en) * 2016-11-11 2017-03-15 上海鸣大生物科技有限公司 One kind is used for treating physical property dermatosiss and the dermopathic external used medicine of animality and its preparation method and application
CN106344613A (en) * 2016-11-11 2017-01-25 上海鸣大生物科技有限公司 Application of NK cell stock solution in preparation of medicine for treating skin diseases
CN106265737A (en) * 2016-11-11 2017-01-04 上海鸣大生物科技有限公司 A kind of external used medicine for treating skin appendages and itching skin disease and its preparation method and application
CN106389467A (en) * 2016-11-11 2017-02-15 上海鸣大生物科技有限公司 External use medicine for treating dermatitis and eczema type skin diseases, and preparation method and application thereof
KR102311057B1 (en) * 2017-12-14 2021-10-08 (주)녹십자웰빙 Cosmetic composition and pharmaceutical composition for improving atopic dermatis, alopetic, wound, or skin wrinkle
KR102014467B1 (en) * 2017-12-14 2019-08-26 (주)녹십자웰빙 Cosmetic composition and pharmaceutical composition for improving atopic dermatis, alopetic, wound, or skin wrinkle
CN108042567A (en) * 2017-12-15 2018-05-18 广州金塞迩中西医结合医院有限公司 For the life assemblage preparation of repair of cartilage and its application
EP3502692A1 (en) * 2017-12-20 2019-06-26 Aposcience AG Potency assay for secretomes
KR102216710B1 (en) * 2019-03-27 2021-02-17 신지섭 NK cell culture medium, NK cell culture method using the above-mentioned additive composition, and cosmetic composition for skin trouble improvement obtained by the above culture method
EP3962493A2 (en) 2019-05-03 2022-03-09 Flagship Pioneering Innovations V, Inc. Methods of modulating immune activity/level of irf or sting or of treating cancer, comprising the administration of a sting modulator and/or purinergic receptor modulator or postcellular signaling factor
EP3842064A1 (en) 2019-12-23 2021-06-30 Aposcience AG Composition for treating or preventing an allergy or allergic reaction
CN111334472A (en) * 2020-03-27 2020-06-26 郑州鲲鹏健康科技有限公司 PBMC (peripheral vascular endothelial cell) in-vitro 3D collagen hydrogel culture medium and preparation method thereof
CN111773249A (en) * 2020-07-31 2020-10-16 上海鸣大生物科技有限公司 Composition and preparation method thereof
WO2022140457A1 (en) 2020-12-21 2022-06-30 Flagship Pioneering Innovations V, Inc. Use of cell turnover factors for increasing tissue regeneration
EP4074320A1 (en) 2021-04-13 2022-10-19 Aposcience AG Treatment of skin scars
EP4197547A1 (en) * 2021-12-20 2023-06-21 Aposcience AG Composition for treating or preventing vasculitis and diseases associated with vasculitis

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2320491A1 (en) * 1998-03-30 1999-10-07 I.D.M. Immuno-Designed Molecules Stimulated monocyte derived cells, their preparation and uses
US6372494B1 (en) * 1999-05-14 2002-04-16 Advanced Tissue Sciences, Inc. Methods of making conditioned cell culture medium compositions
AU2003230321B8 (en) * 2002-05-09 2009-07-30 Medigenes A pharmaceutical composition for treatment of wounds containing blood plasma or serum
US20070110737A1 (en) * 2003-12-29 2007-05-17 Allan Mishra Compositions and method for decreasing the appearance of skin wrinkles
WO2005085424A2 (en) * 2004-03-09 2005-09-15 Absorber Ab Endothelial progenitor cells and methods of use thereof
US20060004189A1 (en) * 2004-07-02 2006-01-05 James Gandy Compositions for treating wounds and processes for their preparation
CA2613193A1 (en) * 2005-06-24 2007-01-04 Ramtin Agah Thrombospondin-1 derived peptides and treatment methods
RU2295963C1 (en) * 2005-10-18 2007-03-27 Закрытое акционерное общество Научно-производственное предприятие "Тринита" Method for producing immunostimulator
EP2019590A4 (en) * 2006-05-03 2011-08-03 Therakos Inc Methods for treating diseases involving stress-related diseases and conditions
BRPI0919804A8 (en) * 2008-10-05 2016-10-11 Friedlander Hymie METHODS AND COMPOSITION FOR THE TREATMENT OF DERMATOLOGICAL PROBLEMS AND/OR HAIR CONDITIONS
EP2201954A1 (en) * 2008-12-18 2010-06-30 Aposcience AG Pharmaceutical preparation

Also Published As

Publication number Publication date
CA2746862C (en) 2017-08-29
NZ593364A (en) 2012-11-30
CA2746862A1 (en) 2010-07-15
BRPI0922174A2 (en) 2015-12-29
US11235003B2 (en) 2022-02-01
EP2198873A1 (en) 2010-06-23
WO2010079086A1 (en) 2010-07-15
CN102256608B (en) 2013-12-04
AU2009336668B2 (en) 2014-05-08
RU2011129676A (en) 2013-01-27
EP2379085A1 (en) 2011-10-26
EP2379085B1 (en) 2013-07-10
RU2533253C2 (en) 2014-11-20
ES2429518T3 (en) 2013-11-15
JP5869343B2 (en) 2016-02-24
PL2379085T3 (en) 2014-01-31
US20120045418A1 (en) 2012-02-23
CN102256608A (en) 2011-11-23
JP2012512842A (en) 2012-06-07
AU2009336668A1 (en) 2011-07-07

Similar Documents

Publication Publication Date Title
ZA201104349B (en) Pharmaceutical preparation comprising supernatant of blood mononuclear cell culture
HK1250313A1 (en) Stable pharmaceutical composition and methods of using same
ZA201008392B (en) Treatment of pluripotent cells
PT2257155T (en) Cryopreservation of biological cells and tissues
IL215643A0 (en) Stable high protein concentration formulations of human anti-tnf-alpha-antibodies
GB0622394D0 (en) Differentiation of pluripotent cells
PL2643010T3 (en) Biologically active complex and its preparation
EP2227540A4 (en) De-differentiation of human cells
HUE056843T2 (en) Infusion of drugs
HK1221748A1 (en) Bifidobacterium having activity of reducing amount of intestinal putrefacted substance
IL219901A0 (en) Pharmaceutical composiitons for the stimulation of stem cells
EP2606916A4 (en) Biological implant
GB0911042D0 (en) Treatment of tumorigenic cells in solid tumours
EP2185720A4 (en) Biological encoding of large numbers of cells
GB0808413D0 (en) Stabilisation of blood cell conjugates
EP2619571A4 (en) Human b1 cells and uses thereof
HK1131039A1 (en) Pharmaceutical use of sophoricoside
EP2636415A4 (en) Cell adhesive material for biological tissue
HUP1000407A2 (en) Ph dependent pulsatile and sustained release pharmaceutical composition
HK1157387A1 (en) Use of hsa-producing cells
EP2171069A4 (en) Delivery of nucleic acids into genomes of human stem cells using in vitro assembled mu transposition complexes
EP2651430A4 (en) Biological activity of placental protein 13
GB201019937D0 (en) Biologically active complex and its preparation
AU2009904390A0 (en) Provision of animal healthcare
GB0808280D0 (en) Methods of preparing cell populations