ZA200902278B - Aminomethyl-4-imidazoles - Google Patents

Aminomethyl-4-imidazoles

Info

Publication number: ZA200902278B
Authority: ZA; South Africa
Prior art keywords: imidazoles; aminomethyl
Prior art date: 2006-10-19

Application number

ZA200902278A

Other languages

English (en)

Inventor

Guido Galley

Annick Goergler

Zbinden Katrin Groebke

Roger Norcross

Henri Stalder

Original Assignee

Hoffmann La Roche

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2006-10-19

Filing date

2009-04-01

Publication date

2010-03-31

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=38876376&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ZA200902278(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2009-04-01 Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche

2010-03-31 Publication of ZA200902278B publication Critical patent/ZA200902278B/xx

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives

ZA200902278A 2006-10-19 2009-04-01 Aminomethyl-4-imidazoles ZA200902278B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
EP06122586		2006-10-19

Publications (1)

Publication Number	Publication Date
ZA200902278B true ZA200902278B (en)	2010-03-31

Family

ID=38876376

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA200902278A ZA200902278B (en)	2006-10-19	2009-04-01	Aminomethyl-4-imidazoles

Country Status (20)

Country	Link
US (1)	US8586617B2 (xx)
EP (1)	EP2076497B1 (xx)
JP (2)	JP5335681B2 (xx)
KR (1)	KR101176699B1 (xx)
CN (1)	CN101528710B (xx)
AR (1)	AR063327A1 (xx)
AT (1)	ATE546437T1 (xx)
AU (1)	AU2007312390B2 (xx)
BR (1)	BRPI0717939A2 (xx)
CA (1)	CA2666762C (xx)
CL (1)	CL2007002971A1 (xx)
ES (1)	ES2381589T3 (xx)
IL (1)	IL197877A (xx)
MX (1)	MX2009003801A (xx)
NO (1)	NO20091478L (xx)
PE (1)	PE20080889A1 (xx)
RU (1)	RU2009112496A (xx)
TW (1)	TW200833685A (xx)
WO (1)	WO2008046757A1 (xx)
ZA (1)	ZA200902278B (xx)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
MX2009003939A (es) *	2006-10-19	2009-05-11	Hoffmann La Roche	Derivados de imidazolona e imidazolidinona como inhibidores de la 11-beta-hidroxiesteroide deshidrogenasa de tipo 1 para diabetes.
CA2666762C (en)	2006-10-19	2014-12-30	F. Hoffmann-La Roche Ag	Aminomethyl-4-imidazoles
EP2562162B1 (en) *	2008-01-22	2015-08-19	Dow AgroSciences LLC	N-cyano-4-amino-5-fluoro-pyrimidine derivatives as fungicides
US8242153B2 (en) *	2008-07-24	2012-08-14	Hoffmann-La Roche Inc.	4,5-dihydro-oxazol-2YL derivatives
CN104521977A (zh) *	2008-08-01	2015-04-22	陶氏益农公司	5-氟胞嘧啶作为杀真菌剂的用途
US8933227B2 (en) *	2009-08-14	2015-01-13	Boehringer Ingelheim International Gmbh	Selective synthesis of functionalized pyrimidines
US8729265B2 (en)	2009-08-14	2014-05-20	Boehringer Ingelheim International Gmbh	Regioselective preparation of 2-amino-5-trifluoromethylpyrimidine derivatives
US8354441B2 (en) *	2009-11-11	2013-01-15	Hoffmann-La Roche Inc.	Oxazoline derivatives
US9452980B2 (en)	2009-12-22	2016-09-27	Hoffmann-La Roche Inc.	Substituted benzamides
US8969349B2 (en)	2010-05-26	2015-03-03	Sunovion Pharmaceuticals Inc.	Substituted quinoxalines and quinoxalinones as PDE-10 inhibitors
KR101651208B1 (ko)	2014-02-19	2016-08-26	충북대학교 산학협력단	클로로겐산 유도체 화합물 및 이를 유효성분으로 포함하는 항염증 및 피부미백용 조성물
WO2017001936A2 (en) *	2015-07-01	2017-01-05	Lifesci Pharmaceuticals, Inc.	Therapeutic inhibitory compounds
CN107531613B (zh) *	2016-02-03	2021-02-05	华东理工大学	苯并脂肪环取代烷基胺类化合物及其用途
MY195528A (en)	2016-03-17	2023-01-30	Hoffmann La Roche	5-Ethyl-4-Methyl-Pyrazole-3-Carboxamide Derivative Having Activity as Agonist of Taar
WO2017190050A1 (en) *	2016-04-28	2017-11-02	Cornell University	Inhibitors of soluble adenylyl cyclase
EP3463359A4 (en) *	2016-06-02	2020-08-26	Purdue Pharma LP	SPURENAMINE-ASSOCIATED RECEPTOR-1 AGONISTS AND PARTIAL AGONISTS FOR PAIN MANAGEMENT
WO2023033680A1 (en)	2021-09-01	2023-03-09	Limited Liability Company «Excellena Research And Development» (Llc «Excellena»)	Substituted 2,3,4,5-tetrahydrobenzo[ f][1,4]oxazepines as modulators of trace amine-associated receptor 1 (taar1)
WO2023033681A1 (en)	2021-09-01	2023-03-09	Limited Liability Company «Excellena Research And Development» (Llc «Excellena»)	Substituted 2-(5-aryl-4 h-1,2,4-triazol-3-yl)ethanamines as modulators of trace amine-associated receptor 1 (taar1)
WO2023033679A1 (en)	2021-09-01	2023-03-09	Limited Liability Company «Excellena Research And Development» (Llc «Excellena»)	(azacycloalkyl)methoxy-substituted benzamides as modulators of trace amine-associated receptor 1 (taar1)

Family Cites Families (69)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US2731471A (en)		1956-01-17		Nxg hi
FR6551E (fr)	1905-07-27	1906-12-17	Carlo Chiesa	Séchoir à tambour rotatif, démontable et transportable, et fonctionnant à ciel ouvert, pour cocons, céréales, etc.
US2161938A (en)	1934-07-31	1939-06-13	Soc Of Chemical Ind	Imidazolines
US2457047A (en)	1946-02-13	1948-12-21	Monsanto Chemicals	2-(2'-thenyl)-4, 5-dihydroimidazoles and process for making the same
US2778836A (en)	1954-04-02	1957-01-22	Union Chimique Belge Sa	Substituted 2-methyl-delta2 imidazolines
US2744910A (en)	1955-06-27	1956-05-08	Bristol Lab Inc	2-(ortho-benzylbenzyl)-imidazoline and acid addition salts
US2744909A (en)	1955-06-27	1956-05-08	Bristol Lab Inc	2-(ortho-phenylbenzyl) imidazoline and acid addition salts
US2919274A (en)	1957-09-17	1959-12-29	Sahyun Melville	Amidines
GB877306A (en)	1958-04-21	1961-09-13	Pfizer & Co C	Halogenated derivatives of tetrahydro-1-naphthyl cyclic amidines
DE1121054B (de)	1960-11-23	1962-01-04	Merck Ag E	Verfahren zur Herstellung eines neuen Imidazolinderivates und dessen Saeureadditionssalzen
US3190802A (en)	1961-10-09	1965-06-22	Boehringer Sohn Ingelheim	Shaving composition and method of using same
DE1150180B (de)	1962-04-12	1963-06-12	Merck Ag E	Mittel zur Vorbehandlung der Haut fuer die Rasur
ES323985A1 (es)	1966-02-26	1966-12-16	Blade Pique Juan	Procedimiento para la obtenciën de derivados del imidazol
US3377247A (en)	1967-04-28	1968-04-09	Dow Chemical Co	Antidepressant method
US3586695A (en)	1968-01-26	1971-06-22	Dow Chemical Co	Substituted imidazolinyl indoles
BE754935A (fr)	1969-08-13	1971-02-17	Hoechst Ag	2-(thienyl-3'-amino)-1,3-diazacycloalcenes et leur preparation
US3622579A (en)	1969-08-28	1971-11-23	Boehringer Sohn Ingelheim	Derivatives of 2-anilino-1,3-diazacyclopentene-(2)
US3818094A (en)	1969-08-28	1974-06-18	Boehringer Sohn Ingelheim	Hypotensive pharmaceutical compositions containing certain 2-anilino-1,3-diazacyclopentenes-(2)
US3660423A (en)	1970-02-13	1972-05-02	Dow Chemical Co	2-(substituted benzyl)methyl-2-imidazolines
GB1333471A (en)	1971-01-27	1973-10-10	Labaz	Imidazoline derivatives and process for preparing the same
US4125620A (en)	1974-10-01	1978-11-14	Boehringer Ingelheim Gmbh	2-[(2',6'-Disubstituted-phenyl)-imino]-imidazolidines and salts thereof
US3992403A (en)	1975-05-30	1976-11-16	Schering Corporation	2-Imidazolines and their use as hypoglycemic agents
GB1538097A (en)	1976-01-26	1979-01-10	Lafon Labor	Substituted phenyl-amidines
US4323570A (en)	1978-11-15	1982-04-06	Beiersdorf Aktiengesellschaft	Substituted aminopyrimidines
AU518569B2 (en)	1979-08-07	1981-10-08	Farmos-Yhtyma Oy	4-benzyl- and 4-benzoyl imidazole derivatives
GB2110663B (en) *	1981-12-04	1985-08-07	Farmos Group Ltd	Imidazole derivatives
US4505918A (en) *	1982-11-08	1985-03-19	Merck & Co., Inc.	4-[2-Pyridinylthio(oxy or amino)methyl]-1H-imidazoles and derivatives
US4540705A (en)	1983-03-14	1985-09-10	Sterling Drug Inc.	Antidepressant imidazolines and related compounds
DE3583900D1 (de)	1984-06-06	1991-10-02	Abbott Lab	Adrenergische verbindungen.
US4665095A (en)	1985-12-11	1987-05-12	Abbott Laboratories	Use of 2-[(3,5-dihalo-4-aminobenzyl)]imidazolines to stimulate alpha-1 adrenergic receptors and to treat nasal congestion
JPH0774205B2 (ja) *	1986-12-04	1995-08-09	三井石油化学工業株式会社	新規イミダゾ−ル誘導体
GB2215206B (en)	1988-02-29	1991-07-03	Farmos Oy	4-substituted imidazole derivatives useful in perioperative care
FI894911A0 (fi)	1989-10-17	1989-10-17	Farmos Oy	En terapeutiskt vaerdefull foerening.
FR2692893B1 (fr) *	1992-06-24	1994-09-02	Sanofi Elf	Dérivés alkylamino ramifiés du thiazole, leurs procédés de préparation et les compositions pharmaceutiques qui les contiennent.
CA2211325C (en)	1993-10-13	2006-08-15	H. Joseph Horacek	Extended release clonidine formulation
GB9425211D0 (en)	1994-12-14	1995-02-15	Ucb Sa	Substituted 1H-imidazoles
US5610174A (en)	1995-06-02	1997-03-11	Synaptic Pharmaceutical Corporation	Use of α1A -selective adrenoceptor agonists for the treatment of urinary incontinence
GB9520150D0 (en)	1995-10-03	1995-12-06	Orion Yhtymae Oy	New imidazole derivatives
DE19607487C2 (de)	1996-02-28	1998-09-10	Byk Gulden Lomberg Chem Fab	Verwendung von alpha1-Adrenoceptor-Antagonisten
US5969137A (en)	1996-09-19	1999-10-19	Virginia Commonwealth University	Benzylamidine derivatives with serotonin receptor binding activity
IL123232A0 (en)	1997-02-11	1999-11-30	Lilly Co Eli	Medicament for inhibiting glucose metabolism deterioration
US5866579A (en)	1997-04-11	1999-02-02	Synaptic Pharmaceutical Corporation	Imidazole and imidazoline derivatives and uses thereof
US6841684B2 (en)	1997-12-04	2005-01-11	Allergan, Inc.	Imidiazoles having reduced side effects
IL136388A0 (en)	1997-12-04	2001-06-14	Allergan Sales Inc	Substituted imidazole derivatives having agonist-like activity at alpha 2b or 2b/2c adrenergic receptors
WO1999032482A1 (en)	1997-12-19	1999-07-01	Eli Lilly And Company	Hypoglycemic imidazoline compounds
ATE293102T1 (de)	1998-04-23	2005-04-15	Takeda Pharmaceutical	Naphthalene derivate ,ihre herstellung und verwendung
ES2150378B1 (es)	1998-08-07	2001-07-01	Esteve Labor Dr	Empleo de derivados de aril(o heteroaril)azolilcarbinoles en la elaboracion de un medicamento para el tratamiento de los trastornos mediados por un exceso de substancia p.
CA2246027A1 (en)	1998-08-27	2000-02-27	Virginia Commonwealth University	Benzylamidine derivatives with serotonin receptor binding activity
PE20010781A1 (es)	1999-10-22	2001-08-08	Takeda Chemical Industries Ltd	Compuestos 1-(1h-imidazol-4-il)-1-(naftil-2-sustituido)etanol, su produccion y utilizacion
FI20000073A0 (fi)	2000-01-14	2000-01-14	Orion Yhtymae Oy	Uusia imidatsolijohdannaisia
JP2001302643A (ja)	2000-04-21	2001-10-31	Suntory Ltd	環状アミジン化合物
EP1319070A2 (en)	2000-09-12	2003-06-18	Oregon Health & Science University	Mammalian receptor genes and uses
PL362549A1 (en)	2000-11-14	2004-11-02	F.Hoffmann-La Roche Ag	Substituted 2-phenylaminoimidazoline phenyl ketone derivatives as ip antagonists
IL147921A0 (en)	2002-01-31	2002-08-14	Abdulrazik Mohammad	A method for treating central nervous system disorders by ocular dosing
TW200306783A (en)	2002-04-29	2003-12-01	Fmc Corp	Pesticidal heterocycles
KR100492252B1 (ko)	2002-08-09	2005-05-30	한국화학연구원	이미다졸을 포함하는 이차아민으로 치환된 벤조피란유도체 및 그의 제조방법
AU2003288899B2 (en) *	2002-08-23	2009-09-03	Novartis Vaccines And Diagnostics, Inc.	Benzimidazole quinolinones and uses thereof
KR101088922B1 (ko) *	2002-09-04	2011-12-01	파마코페이아, 엘엘씨.	사이클린 의존성 키나제 억제제로서의 피라졸로피리미딘
NZ539193A (en)	2002-09-05	2008-04-30	Aventis Pharma Sa	Novel aminoindazole derivatives as medicines and pharmaceutical compositions containing same
KR20080009144A (ko) *	2005-05-03	2008-01-24	바이엘 크롭사이언스 아게	살충성을 가지는 치환된 아미노알킬 헤테로사이클릭 및헤테로아릴 유도체
US20090170907A1 (en) *	2005-06-06	2009-07-02	Smithkline Beecham Corporation	Chemical Compounds
BRPI0615307A2 (pt)	2005-08-25	2009-08-04	Schering Corp	agonistas de adrenorreceptor alfa2c
EP2130822A1 (en)	2005-12-01	2009-12-09	F. Hoffmann-La Roche AG	2,4,5-triphenyl imidazoline derivatives as inhibitors of the interaction between p53 and mdm2 proteins for use as anticancer agents
UY30097A1 (es)	2006-01-20	2007-08-31	Atugen Ag	Usos terapeuticos de inhibidores de rtp801
AU2007209380B2 (en) *	2006-01-27	2011-12-08	F. Hoffmann-La Roche Ag	Use of 4-imidazole derivatives for CNS disorders
MX2009003939A (es)	2006-10-19	2009-05-11	Hoffmann La Roche	Derivados de imidazolona e imidazolidinona como inhibidores de la 11-beta-hidroxiesteroide deshidrogenasa de tipo 1 para diabetes.
CA2666762C (en)	2006-10-19	2014-12-30	F. Hoffmann-La Roche Ag	Aminomethyl-4-imidazoles
EP2076496B1 (en)	2006-10-19	2010-03-31	F. Hoffmann-Roche AG	Aminomethyl-2-imidazoles with affinity with the trace amine associated receptors
CL2007002994A1 (es)	2006-10-19	2008-02-08	Wyeth Corp	Compuestos derivados heterociclicos que contienen sulfamoilo, inhibidores de hsp90; composicion farmaceutica; y uso para el tratamiento del cancer, tal como cancer de mama, de colon y prostata, entre otros.

2007
- 2007-10-09 CA CA2666762A patent/CA2666762C/en not_active Expired - Fee Related
- 2007-10-09 AU AU2007312390A patent/AU2007312390B2/en not_active Ceased
- 2007-10-09 MX MX2009003801A patent/MX2009003801A/es active IP Right Grant
- 2007-10-09 JP JP2009532767A patent/JP5335681B2/ja not_active Expired - Fee Related
- 2007-10-09 KR KR1020097007948A patent/KR101176699B1/ko not_active IP Right Cessation
- 2007-10-09 RU RU2009112496/04A patent/RU2009112496A/ru not_active Application Discontinuation
- 2007-10-09 WO PCT/EP2007/060666 patent/WO2008046757A1/en active Application Filing
- 2007-10-09 AT AT07821039T patent/ATE546437T1/de active
- 2007-10-09 CN CN2007800388091A patent/CN101528710B/zh not_active Expired - Fee Related
- 2007-10-09 EP EP07821039A patent/EP2076497B1/en not_active Not-in-force
- 2007-10-09 ES ES07821039T patent/ES2381589T3/es active Active
- 2007-10-09 BR BRPI0717939-1A2A patent/BRPI0717939A2/pt not_active IP Right Cessation
- 2007-10-15 US US11/872,203 patent/US8586617B2/en not_active Expired - Fee Related
- 2007-10-17 CL CL200702971A patent/CL2007002971A1/es unknown
- 2007-10-17 AR ARP070104590A patent/AR063327A1/es unknown
- 2007-10-17 TW TW096138932A patent/TW200833685A/zh unknown
- 2007-10-17 PE PE2007001403A patent/PE20080889A1/es not_active Application Discontinuation
2009
- 2009-03-26 IL IL197877A patent/IL197877A/en not_active IP Right Cessation
- 2009-04-01 ZA ZA200902278A patent/ZA200902278B/xx unknown
- 2009-04-17 NO NO20091478A patent/NO20091478L/no not_active Application Discontinuation
2013
- 2013-05-02 JP JP2013096834A patent/JP5567177B2/ja not_active Expired - Fee Related

Also Published As

Publication number	Publication date
US20080119535A1 (en)	2008-05-22
CN101528710A (zh)	2009-09-09
ES2381589T3 (es)	2012-05-29
CL2007002971A1 (es)	2008-05-30
TW200833685A (en)	2008-08-16
PE20080889A1 (es)	2008-06-27
JP2010506875A (ja)	2010-03-04
CA2666762C (en)	2014-12-30
AU2007312390A1 (en)	2008-04-24
AU2007312390B2 (en)	2013-03-28
CN101528710B (zh)	2012-11-07
MX2009003801A (es)	2009-04-22
EP2076497A1 (en)	2009-07-08
ATE546437T1 (de)	2012-03-15
AR063327A1 (es)	2009-01-21
JP5335681B2 (ja)	2013-11-06
BRPI0717939A2 (pt)	2013-12-03
NO20091478L (no)	2009-05-05
IL197877A (en)	2015-07-30
EP2076497B1 (en)	2012-02-22
CA2666762A1 (en)	2008-04-24
JP5567177B2 (ja)	2014-08-06
WO2008046757A1 (en)	2008-04-24
JP2013173779A (ja)	2013-09-05
US8586617B2 (en)	2013-11-19
RU2009112496A (ru)	2010-11-27
KR101176699B1 (ko)	2012-08-23
IL197877A0 (en)	2009-12-24
KR20090055035A (ko)	2009-06-01

Publication	Publication Date	Title
DE602007002700D1 (en)	2009-11-19	Interventionsfreies frac-system
EP2078282A4 (en)	2011-09-28	ELECTRONIC COUPONS
EP2033216A4 (en)	2014-12-24	ELEKTROADHÄSION
DE602007008085D1 (en)	2010-09-09	Dihydropyrazolopyrimidinonderivate
DE602007014031D1 (en)	2011-06-01	Luftreifensatz
DE602007002070D1 (en)	2009-10-01	2-pyrazincarboxamidderivate
DE602007003855D1 (en)	2010-01-28	Isothermer reaktor
ZA200902278B (en)	2010-03-31	Aminomethyl-4-imidazoles
EP1983992A4 (en)	2010-08-18	2-IMINO-BENZIMIDAZOLES
DE602007001601D1 (en)	2009-08-27	Glasuntersuchung
DE602007006989D1 (en)	2010-07-15	Spiropiperidinderivate
AP2008004724A0 (en)	2008-12-31	Substituted1-yl)-azolin-2-aryl-1-hetaryl-ethane
DE602007011622D1 (en)	2011-02-10	Penem-prodrugs
EP2084019A4 (en)	2012-06-27	PAINT SCRAPER
EP2024567A4 (en)	2011-08-24	TONTAPETE
EP2007388A4 (en)	2009-11-25	OPIOPATHIEN
DK1989111T3 (en)	2020-02-10	Satellitluftbremseapparat
EP1974618A4 (en)	2013-05-01	UNDERWEAR
DE502007001126D1 (en)	2009-09-03	Eiten
GB0602258D0 (en)	2006-03-15	Privyphone
AU4914P (en)	2014-09-03	CalflatGL Calothamnus quadrifidus
AU3514P (en)	2008-04-30	ARCBENT Arctotis fastuosa
GB0600180D0 (en)	2006-02-15	Infofob
GB0600344D0 (en)	2006-02-15	Cuffclamp
AU312609S (en)	2007-01-29	Jewellery - pendant